Abstract: An autonomous driving computing system may include an on-board computing system that is configured to perform first operations that include obtaining sensor data relating to an autonomous vehicle (AV). The first operations may include sending the obtained sensor data to an off-board cloud computing system. The autonomous driving computing system may include the off-board cloud computing system, which may be configured to perform second operations that include receiving the sensor data and performing computations relating to the driving operation of the AV based on the obtained sensor data. The second operations may include determining a control signal corresponding to a driving operation and sending the control signal to the on-board computing system. The first operations may involve the on-board computing system receiving, from the off-board cloud computing system, the control signal corresponding to the driving operation of the AV and performing the driving operation by implementing the control signal.

Abstract: A method may include obtaining input information representative of an autonomous vehicle. The input information may include a plurality of data types. Each data type of the plurality of data types may be asynchronous. The method may also include aligning the input information to a point in time. In addition, the method may include determining odometry information indicating a state of the autonomous vehicle at the point in time based on the aligned input information. Further, the method may include sending the odometry information to a downstream system.

Abstract: The invention relates to a method of determining the T cell receptor ? chain (TRBC) gene type of a cell, the method comprising (a) determining the J gene type expressed in said cell, and (b) inferring from (a) the TRBC gene type expressed in said cell. The invention further relates to use of a CAR T cell targeted to a T cell receptor ? chain (TRBC) type 1, or a CAR T cell targeted to a T cell receptor ? chain (TRBC) type 2. The invention further relates to a method of medical treatment, and to nucleic acid probes.

Abstract: The present invention provides a chimeric antigen receptor (CAR) which binds a target antigen having a bulky extra-cellular domain, wherein the CAR comprises a Fab antigen binding domain. The present invention also provides nucleic acid sequences and constructs encoding such a CAR, cells expressing such a CAR and their therapeutic uses.

Abstract: A non-transitory computer readable medium stores instructions that, when executed by a processor, cause the processor to receive, from one or more processing nodes, data representative of usage and inventory of one or more software assets by one or more industrial automation devices of an industrial automation system that are communicatively coupled to the one or more processing nodes, determining a data delta for the industrial automation system that represents differences between the software asset data and a previous iteration of the software asset data, encrypt the data delta for the industrial automation system, and transmit the encrypted data delta for the industrial automation system to a remote server.

Abstract: A method may include obtaining sensor data about a total measurable world around an autonomous vehicle. The sensor data may be captured by sensor units co-located with the autonomous vehicle. The method may include generating a mapping dataset including the obtained sensor data and identifying data elements that each represents a point in the mapping dataset. The method may include sorting the data elements according to a structural data categorization that is a template for a high-definition map of the total measurable world and determining a mapping trajectory of the autonomous vehicle. The mapping trajectory may describe a localization and a path of motion of the autonomous vehicle. The method may include generating the high-definition map based on the structural data categorization and relative to the mapping trajectory of the autonomous vehicle, and the high-definition map may be updated based on the path of motion of the autonomous vehicle.

Abstract: A polyclonal antiserum composition including a repertoire of antigen-specific artificial immunoglobulins, each antigen-specific artificial immunoglobulin including: one or more human heavy chain VH segment(s); one or more D segment(s); one or more J segment(s); and one or more constant region segment(s).

Abstract: Systems and methods for software compatibility prediction and remediation for industrial systems. One system includes an electronic processor configured to receive a software inventory for an industrial system and compatibility data associated with each piece of software included in the software inventory. The electronic processor is also configured to generate, via a compatibility engine, a compatibility mapping based on the software inventory and the compatibility data. The electronic processor is also configured to determine, based on the compatibility mapping, a set of compatibility statuses associated with the industrial system. The electronic processor is also configured to generate a graphical user interface (GUI) for display, the GUI including the software inventory, the set of compatibility statuses, and an interactive graphical representation of the compatibility mapping, and, in response to receiving a user interaction with the GUI, dynamically update the GUI based on the user interaction.

Abstract: The present invention provides a chimeric antigen receptor (CAR) which binds a low density target antigen, which comprises a Fab antigen binding domain. The invention also relates to cells expressing such a CAR and their use in the treatment of disease.

Abstract: A method may include obtaining input information relating to an environment in which an autonomous vehicle (AV) operates, the input information describing at least one of: a state of the AV, an operation of the AV within the environment, a property of the environment, or an object included in the environment. The method may include identifying a first object in the vicinity of the AV based on the obtained input information. The method may include determining a first object rule corresponding to the first object, the first object rule indicating suggested driving behavior for interacting with the first object. The method may include determining a first decision that follows the first object rule and sending an instruction to a control system of the AV, the instruction describing a given operation of the AV responsive to the first object rule according to the first decision.

Abstract: A method may include obtaining sensor data describing a total measurable world around a motion sensor. The method may include processing the sensor data to generate a pre-compensation scan of the total measurable world around the motion sensor based on the sensor data. The method may include determining a delay between the obtaining the sensor data and the generation of the pre-compensation scan. The method may include obtaining motion data corresponding to motion of the motion sensor and generating a motion model of the motion sensor based on the motion data. The method may include generating an after-compensation scan of the motion sensor using the delay and the motion model to compensate for continued motion during the delay.

Abstract: The invention relates to transgenic animals useful for optimal production of functional immunoglobulins with human idiotypes.

Abstract: A waterborne polyurethane dispersion is provided. The waterborne polyurethane dispersion is prepared by using a tri-functionality polyether polyol as part of the polyols for forming the prepolymer and a hydrophilic amino siloxane co-chain extender, and can exhibit superior performance properties such as enhanced color fastness, improved low temperature stability, good anti-stickiness, bally flex resistance, anti-abrasion and mechanical properties. A laminated synthetic leather article prepared with said waterborne polyurethane dispersion as well the method for preparing the synthetic leather article are also provided.

Abstract: The present invention provides a chimeric antigen receptor (CAR) which binds a target antigen having a bulky extracellular domain, wherein the CAR comprises a Fab antigen binding domain. The present invention also provides nucleic acid sequences and constructs encoding such a CAR, cells expressing such a CAR and their therapeutic uses.

Abstract: An internally emulsified polyurethane dispersion, which is prepared by using a combined chain extender system of a hydrophilic amino siloxane compound and a polyetheramine compound, is provided. The internally emulsified polyurethane dispersion can be used to prepare a synthetic leather product having good anti-stickiness, wrinkle resistance, color fastness and superior mechanical properties. A laminated synthetic leather article prepared with said internally emulsified polyurethane dispersion as well a method for preparing the synthetic leather article are also provided.

Abstract: An autonomous driving validation system may include a primary advanced autonomy system located on board an autonomous vehicle (AV) that includes sensors, computing subsystems, and a drive-by-wire system. The primary advanced autonomy system may be configured to process first computations relating to a driving operation of the AV. The autonomous driving validation system may also include an off-board autonomous cloud computing system that includes cloud computing subsystems. The off-board autonomous cloud computing system may be configured to process second computations that are similar to the first computations processed by the primary advanced autonomy system.

Abstract: A method may include obtaining input information relating to an environment in which an autonomous vehicle (AV) operates. The input information may describe a state of the AV, an operation of the AV within the environment, a property of the environment, or an object included in the environment. The method may include setting up a traffic rule profile for the AV that specifies societal traffic practices corresponding to a location of the environment. The method may include identifying a first traffic rule relevant to the AV based on the obtained input information and determining a first decision corresponding to the traffic rule profile and the first traffic rule. The method may include sending an instruction to a control system of the AV, the instruction describing a given operation of the AV responsive to the traffic rule profile and the first traffic rule according to the first decision.

Abstract: A method may include obtaining input information relating to an environment in which an autonomous vehicle (AV) operates in which the input information describes at least one of: a state of the AV, an operation of the AV within the environment, a property of the environment, or an object included in the environment. The method may include identifying a region of interest that represents a section of the environment based on the input information and identifying a portion of the environment based on the identified region of interest. The portion of the environment may include an object that affects operation of the AV. The method may include determining a first decision that relates to the object and sending an instruction to a control system of the AV describing a given operation of the AV responsive to the object according to the first decision.

Abstract: A non-transitory computer readable medium stores instructions that, when executed by a processor, cause the processor to receive, from one or more processing nodes, data representative of usage and inventory of one or more software assets by one or more industrial automation devices of an industrial automation system that are communicatively coupled to the one or more processing nodes, determining a data delta for the industrial automation system that represents differences between the software asset data and a previous iteration of the software asset data, encrypt the data delta for the industrial automation system, and transmit the encrypted data delta for the industrial automation system to a remote server.

Abstract: A method may include identifying computing systems corresponding to an autonomous vehicle (AV) in which each computing system is configured to perform at least one operation relating to driving the AV. The method may include determining whether the computing systems use a first respective real-world parameter as an input to any of the operations or generate a second respective real-world parameter as an output of the operations. A respective operation corresponding to a respective computing system may be designated for accelerated performance based on the determination, and the operations of the computing systems may be performed. A first operation not designated for accelerated performance may include first computations corresponding to the first operation after waiting for a synchronization delay period, and a second operation designated for accelerated performance may include second computations corresponding to the second operation and performed without waiting for the synchronization delay period.