Patents by Inventor Bing Wang

Bing Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEM AND METHOD FOR OPHTHALMIC LASER SURGERY EMPLOYING EYE TRACKING WITHOUT EYE DOCKING
    Publication number: 20140276674
    Abstract: A system and method for performing ophthalmic surgery using an ultra-short pulsed laser is provided. The system includes a laser engine configured to provide an ultra-short pulsed laser beam, optics configured to direct the laser beam to an undocked eye of a patient, an eye tracker configured to measure five degrees of freedom of movement of the undocked eye, an optical coherence tomography module configured to measure depth of the undocked eye, and a controller configured to control laser beam position on the undocked eye toward a desired laser pattern based on depth and the five degrees of freedom of movement of the undocked eye. Adaptive optics are also provided. Also disclosed are a scleral ring including fiducial markings and a compliant contact lens and fluid fillable contact lens configured to facilitate ultra-short pulsed laser surgery while reducing or eliminating eye docking requirements.
    Type: Application
    Filed: March 5, 2014
    Publication date: September 18, 2014
    Inventors: Hon M. Lee, Peter Patrick De Guzman, Victor Kardos, Hong Fu, Robert G. Heitel, John M. Tamkin, Mikhail Levin, Bing Wang
  • ELECTRICAL LINES WITH COUPLING EFFECTS
    Publication number: 20140268977
    Abstract: A circuit includes a first line, a second line, a first sub-circuit, and a second sub-circuit. The first line has a first signal. The second line has a second signal. The first sub-circuit is configured to generate a first output signal. The second sub-circuit is configured to generate a second output signal. The first output signal and the second output signal have coupling effects if the first signal and the second signal have coupling effects based on the first line and the second line. The first output signal and the second output signal do not have coupling effects if the first signal and the second signal do not have coupling effects.
    Type: Application
    Filed: May 13, 2013
    Publication date: September 18, 2014
    Applicant: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.
    Inventors: Bing WANG, Kuoyuan (Peter) HSU
  • MULTIPLE BITCELLS TRACKING SCHEME SEMICONDUCTOR MEMORY ARRAY
    Publication number: 20140247675
    Abstract: A memory array includes a memory segment having at least one memory bank. The at least one memory bank includes an array of memory cells, and wherein at least two first read tracking cells are disposed in a read tracking column of the at least one memory bank. The memory array further includes a read tracking circuit coupled to the at least two first read tracking cells. Outputs of the at least two first read tracking cells are connected to a tracking bit connection line (TBCL). A tracking circuit connected to the TBCL is configured to output a tracking-cells output signal to generate a global tracking result signal to a memory control circuitry. The memory control circuitry is configured to reset a memory clock based on the global tracking result signal.
    Type: Application
    Filed: May 16, 2014
    Publication date: September 4, 2014
    Inventors: Derek C. TAO, Bing WANG, Kuoyuan (Peter) HSU, Jacklyn Victoria CHANG, Young Suk KIM
  • METHODS AND COMPOSITIONS FOR TARGETED POLYNUCLEOTIDE MODIFICATION
    Publication number: 20140237681
    Abstract: A variety of methods and compostions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.
    Type: Application
    Filed: March 17, 2014
    Publication date: August 21, 2014
    Applicant: PIONEER HI BRED INTERNATIONAL INC
    Inventors: William Gordon-Kamm, Keith Lowe, David J. Peterson, Christopher Scelonge, Grace M. St Clair, Bing-Bing Wang
  • CRYSTALLINE (8S,9R)-5-FLUORO-8-(4-FLUOROPHENYL)-9-(1-METHYL-1H-1,2,4-TRIAZOL-5-YL)-8,9-DIHYDRO-2H-PYRIDO[4,3,2-DE]PHTHALAZIN-3(7H)-ONE TOSYLATE SALT
    Publication number: 20140228369
    Abstract: Provided herein are (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt forms, including crystalline forms, and methods of their preparation. Pharmaceutical compositions comprising a (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt are also provided, as are methods of using (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt to treat a disease or condition, such as a cancer.
    Type: Application
    Filed: April 14, 2014
    Publication date: August 14, 2014
    Applicant: BioMarin Pharmaceutical Inc.
    Inventors: Bing Wang, Daniel Chu, Yongbo Liu, Shichun Peng
  • WATER DRAIN ACCELERATING DEVICE
    Publication number: 20140216583
    Abstract: A water drain accelerating device has a base with a discharge port connected to a flush way assembled inside a water tank. An overflow hole is connected to the discharge port. An overflow pipe is plugged to the base. The bottom of the overflow pipe is connected to the overflow hole. A negative pressure pipe is connected to the overflow pipe. Negative pressure generates inside the overflow pipe when the base is draining. Water inside the water tank flows out of the discharge port when water drains. The water level inside the cavity of the negative pressure pipe falls down with the water level inside the water tank. Negative pressure generates inside the overflow pipe, so air inside the overflow pipe can't enter into the discharge port through the overflow hole. An air pipe extends from the overflow hole to the flush way.
    Type: Application
    Filed: April 22, 2013
    Publication date: August 7, 2014
    Applicant: XIAMEN R&T PLUMBING TECHNOLOGY CO., LTD.
    Inventors: Youping JIANG, Rongyu Zhang, Xingdong Wang, Bing Wang
  • Chroman derivatives
    Patent number: 8791155
    Abstract: The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondria) disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: July 29, 2014
    Assignee: Edison Pharmaceuticals, Inc.
    Inventors: Bing Wang, Gail Walkinshaw, Donald R. James
  • ORGANIC MONTMORILLONITE ENHANCED EPOXY RESIN AND PREPARATION METHOD THEREOF
    Publication number: 20140200289
    Abstract: An organic montmorillonite enhanced epoxy resin and a preparation method thereof are provided. The preparation method of the organic montmorillonite enhanced epoxy resin includes adding an organic montmorillonite exfolicated by an organic solvent and a coupling agent to increase the thermal stability and reliability of the epoxy resin.
    Type: Application
    Filed: June 4, 2013
    Publication date: July 17, 2014
    Inventors: Xin WANG, Jin-Chang Wu, Wen-bing Wang
  • Signal tracking in write operations of memory cells
    Patent number: 8780652
    Abstract: In a method, a first edge of a first tracking signal in a first direction of a memory array is generated. A first edge of a second tracking signal in a second direction of the memory array is generated. A first edge of a write-timing control signal is generated based on a slower edge of the first edge the first tracking signal and of the first edge of the second tracking signal. The first edge of the write-timing control signal is used to generate a second edge of the second tracking signal.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: July 15, 2014
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Bing Wang, Kuoyuan (Peter) Hsu, Young Suk Kim
  • Processes of synthesizing dihydropyridophthalazinone derivatives
    Patent number: 8765945
    Abstract: Provided herein are processes for synthesizing dihydropyridophthalazinone derivatives, such as for example, 5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one and its stereoisomers, which are potent poly(ADP-ribose)polymerase (PARP) inhibitors as well as novel synthetic intermediate compounds.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: July 1, 2014
    Assignee: BioMarin Pharmaceutical Inc.
    Inventors: Bing Wang, Daniel Chu, Yongbo Liu, Quan Jiang, Lei Lu
  • Preparation method of Rosuvastatin calcium and its intermediates
    Patent number: 8765947
    Abstract: A preparation method of rosuvastatin calcium (Formula 1), which can be used for the production of medicament lowering the levels of LDL-cholesterol and triglycerides in vivo, is provided. Such preparation method is suitable for industrial production. Furthermore, the intermediate crystallines used in the preparation method are provided.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: July 1, 2014
    Assignee: Changzhou Pharmaceutical Factory
    Inventors: Benshun Chen, Bing Wang, Xiaofeng Jin, Lin Zou
  • Multiple bitcells tracking scheme semiconductor memory array
    Patent number: 8760948
    Abstract: A read tracking system and method for advanced memory devices are provided. The read tracking system and method include tracking multiple tracking bit cells in multiple segments and columns to incorporate device performance variation of bit cells in the memory array. The tracking path mimics the worst-case read path with some built-in margins to sufficiently and efficiently cover the read times of bit cells in a memory array without unnecessarily sacrificing the read speed performance of the memory array. A number of tracking cells may be placed at different segments and both sides of the memory array to cover read time variation across memory array.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: June 24, 2014
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Derek C. Tao, Bing Wang, Kuoyuan (Peter) Hsu, Jacklyn Victoria Chang, Young Suk Kim
  • AKT PROTEIN KINASE INHIBITORS
    Publication number: 20140148436
    Abstract: The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
    Type: Application
    Filed: January 31, 2014
    Publication date: May 29, 2014
    Applicant: Array BioPharma, Inc.
    Inventors: Ian S. Mitchell, Keith L. Spencer, Peter Stengel, Yongxin Han, Nicolas C. Kallan, Mark Munson, Guy P.A. Vigers, James Blake, Anthony Piscopio, John Josey, Scott Miller, Dengming Xiao, Rui Xu, Chang Rao, Bing Wang, April L. Bernacki
  • Crystalline (8,9)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1-1,2,4-triazol-5-yl)-8,9-dihydro-2-pyrido[4,3,2-de]phthalazin-3(7)-one tosylate salt
    Patent number: 8735392
    Abstract: Provided herein are (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt forms, including crystalline forms, and methods of their preparation. Pharmaceutical compositions comprising a (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt are also provided, as are methods of using (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt to treat a disease or condition, such as a cancer.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: May 27, 2014
    Assignee: BioMarin Pharmaceutical Inc.
    Inventors: Bing Wang, Daniel Chu, Yongbo Liu, Shichun Peng
  • SCREW LOCKING DEVICE
    Publication number: 20140137706
    Abstract: A screw locking device includes a feeding mechanism, a conveying mechanism, and a pneumatic screw driver. The conveying mechanism includes a base, a pneumatic driver slidably mounted on the base, a pair of blocking members slidably mounted on the base, a conveying bridge, a flexible tube, and a controller. Each blocking member includes a blocking end positioned below the pneumatic driver. The conveying bridge communicates with the feeding mechanism, and extends to the blocking ends. The flexible tube aligned with a gap between the blocking ends, and communicates with the pneumatic screw driver.
    Type: Application
    Filed: November 14, 2013
    Publication date: May 22, 2014
    Applicants: HON HAI PRECISION INDUSTRY CO., LTD., FU DING ELECTRONICAL TECHNOLOGY (JIASHAN) CO.,LTD.
    Inventors: JIN-HUA LU, DA-ZHUANG XU, XUE-BING WANG
  • LACTOFERRIN AND GUT NEURONAL HEALTH IN ADULTS AND/OR ELDERLY
    Publication number: 20140135262
    Abstract: The present invention relates generally to the field of neuronal health and neuronal protection. One embodiment of the present invention relates to a composition that can be used for the protection of the enteric nervous system from neurodegeneration. Disorders linked to an impaired enteric nervous system can be treated or prevented by the administration of lactoferrin containing compositions according to the present invention.
    Type: Application
    Filed: November 6, 2013
    Publication date: May 15, 2014
    Applicant: NESTEC S.A.
    Inventors: Magali Faure, Bing Wang, Jeroen Schmitt
  • HEIGHT ADJUSTING MECHANISM FOR AN INLET VALVE
    Publication number: 20140124047
    Abstract: A height adjusting mechanism for an inlet valve includes a valve body, and inlet pipe, a retaining member and an actuator. The inlet pipe is sleeved in the valve body and connected to the valve body; the retaining member is assembled in the valve body; and the actuator can drive the retaining member to move to make the valve body fixed to the inlet pipe or moved relatively to the inlet pipe in the axial direction. The actuator drives the retaining member to move in order to let the valve body and the inlet pipe to be fixed or moved relatively to each other in the axial direction. There is no need to rotate the valve body during adjusting process, and the float won't affect the tank wall when the water valve body is rotating.
    Type: Application
    Filed: March 6, 2013
    Publication date: May 8, 2014
    Applicant: XIAMEN R&T PLUMBING TECHNOLOGY CO., LTD.
    Inventors: Guiyang HUANG, Zhijun Zhong, Bing Wang
  • Methods and compositions for targeted polynucleotide modification
    Patent number: 8704041
    Abstract: A variety of methods and compostions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: April 22, 2014
    Assignee: Pioneer Hi Bred International Inc
    Inventors: William J. Gordon-Kamm, Keith S. Lowe, David J. Peterson, Christopher J. Scelonge, Grace M. St. Clair, Bing-Bing Wang
  • Organic compounds
    Patent number: 8703761
    Abstract: The invention relates to compounds of formula (I): where A is an optionally substituted heteroaryl, useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: April 22, 2014
    Assignee: Novartis AG
    Inventors: Cornelia Jutta Forster, Young-Shin Kwak, Katsumasa Nakajima, Bing Wang
  • TWO-PORT SRAM WRITE TRACKING SCHEME
    Publication number: 20140092675
    Abstract: A write tracking control circuit includes an input node, and a first transistor configured to pre-charge a word bit line connected to at least two memory cells. The write tracking control circuit further includes a second transistor configured to pre-charge a read bit line connected to the at least two memory cells. The write tracking control circuit further includes a first delay circuit between the input node and the first transistor, the first delay circuit configured to introduce a first delay time, wherein a gate of the first transistor is connected to the first delay circuit. The write tracking control circuit further includes a second delay circuit between the input node and the second transistor, the second delay circuit configured to introduce a second delay time different from the first delay time, wherein a gate of the second transistor is connected to the second delay circuit.
    Type: Application
    Filed: December 3, 2013
    Publication date: April 3, 2014
    Applicant: TAIWAN SIMICONDUCTOR MANUFACTURING COMPANY, LTD.
    Inventors: Bing WANG, Kuoyuan (Peter) HSU, Derek C. TAO