Abstract: A method of detecting the presence of a prostate cancer field defect in a human subject. The method includes (a) obtaining genomic DNA from the human subject and (b) determining methylation status in at least one target region selected from the group consisting of PLA2G16, CAV1, EVX1, MCF2L, FGF1, NCR2, WNT2, EXT1, and SPAG4, wherein methylation changes indicate the presence of prostate cancer or a prostate cancer field defect, wherein the change is relative to tissue from a second human subject who does not have prostate cancer.

Abstract: An optical element, an optical element monitoring system, and a method, monitor in real time whether an optical element such as a diffractive optical element or a diffuser in an active light emitting module is damaged or falls off, and turn off a laser when the optical element is damaged or falls off.

Abstract: A method of detecting the presence of a prostate cancer field defect in a human subject comprising the step of (a) obtaining genomic DNA from the human subject and (b) quantitating methylation in at least one target region selected from the group consisting of PLA2G16, CAV1, EVX1, MCF2L, FGF1, NCR2 and WNT2 and EXT1 and SPAG4 target, wherein significant methylation changes indicate the presence of prostate cancer or a prostate cancer field defect, wherein the change is relative to tissue from a second human subject who does not have prostate cancer.

Abstract: An isolated anti-SCUBE2 antibody or a binding fragment thereof is disclosed. The anti-SCUBE2 antibody comprises an antigen binding region that specifically binds to a target domain located within SCUBE2 (SEQ ID NO: 66) and exhibits a property of inhibiting VEGF-induced angiogenesis. The target domain is selected from the group consisting of the EGF-like motifs 4 to 6 ranging from a.a. position 175 to 323, or the spacer region ranging from a.a. position 441 to 659, or the first cys-rich motif ranging from a.a. position 668 to 725 of SCUBE2 (SEQ ID NO: 66). The anti-SCUBE2 antibody or binding fragment thereof is for use in treating a disease associated with VEGF-induced angiogenesis, or for use in treating a tumor or inhibiting tumor angiogenesis and cancer cell growth in a subject in need thereof.

Abstract: A network search and configuration method, a registration method, a device, and a system are provided. The network search and configuration method is applied to a server, and comprises: receiving a service request carrying location information sent by a communication terminal; obtaining various optimal parameters in a SIM card to be registered corresponding to the location information according to the service request; dynamically configuring the various parameters in the SIM card to be registered according to various optimal parameters; and sending the dynamically configured SIM card to be registered to the communication terminal in order that the communication terminal searches and registers a network for the SIM card to be registered according to various configured parameters accordingly.

Abstract: An isolated anti-SCL)BE2 (Signal peptide-complement protein Clr/CIs, Uegf: and Bmp 1 (CUB)-epidermal growth factor (EGF) domain-containing protein 2) antibody or a binding fragment thereof is disclosed. The anti-SCUBE2 antibody comprises an antigen binding region that specifically hinds to a target domain located within SCUBE2 (SEQ ID NO: 66) and exhibits a property of inhibiting vascular endothelial growth factor (VEGF)-induced angiogenesis. The target domain is selected from the group consisting of the EGF-like motifs 4 to 6 ranging from a.a. position 175 to 323, or the spacer region ranging from a.a. position 441 to 659, or the first cys-rich motif ranging from a.a. position 668 to 725 of SCUBE2 (SEQ ID NO: 66). The anti-SCUBE2 antibody or binding fragment thereof is for use in treating a disease associated with VEGF-induced angiogenesis, or in treating a tumor or inhibiting tumor angiogenesis and cancer cell growth in a subject in need thereof.

Abstract: A method for fabricating semiconductor device includes the steps of: forming a gate structure on a substrate; forming a first spacer and a second spacer around the gate structure; forming a recess adjacent to two sides of the second spacer; performing a cleaning process to trim the second spacer for forming a void between the first spacer and the substrate; and forming an epitaxial layer in the recess.

Abstract: A semiconductor device and a method for fabricating the semiconductor device are provided, in which the method includes the steps of forming a gate structure on a substrate, forming a spacer on a sidewall of the gate structure, forming two recesses adjacent to two sides of the spacer, performing a cleaning process to trim the spacer for forming a void between the spacer and the substrate, and forming two portions of an epitaxial layer in the two recesses. The semiconductor device preferably includes a cap layer on the two portions of the epitaxial layer as the cap layer includes a planar top surface and an inclined sidewall.

Abstract: A closing control method for a high-voltage DC circuit breaker. The method comprises: closing breaking units of the transfer branch (2) group by group, then closing the main branch (1), and finally open the transfer branch. During the process of closing the breaking units of the transfer branch group by group, determine whether there is a fault in the power transmission system after closing current breaking unit group. if there is no fault, proceed to close the next breaking unit group until all breaking unit groups are closed before proceeding to the next step; if there is a fault, all the breaking units that have been closed are opened and the closing operation is ended. The method can pre-charge the power transmission system during the closing process of the high-voltage DC circuit breaker, and lower the overvoltage and system oscillation caused by the closing operation.

Abstract: The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating virus infection in the respiratory tract and virus transmission through the respiratory tract. In particular, the presently-disclosed subject matter relates to inhibiting and treating virus infection in a subject using compositions and antibodies that trap viruses in mucus of the respiratory tract, thereby inhibiting transport of virus across or through mucus secretions.

Abstract: An audio device includes a casing, a handle frame downwardly extended from a bottom side of the casing, a speaker assembly and a PCB board are received in the casing, and a microphone supported on the casing in a dynamic manner for preventing a vibration of the casing directly transmitted to the microphone. The microphone and the speaker assembly are electrically connected to the PCB board, such that the speaker assembly is adapted for instantly play back a sound signal collected by the microphone. The audio device of the present invention has an advantages of high impedance, good sound quality, and strong omni-directional ability, such that the electro-acoustic conversion effect and overall performance of the audio device is enhanced. At the same time, the audio device has a built-in speaker to instantly play back the sound collected by the microphone so as to fulfill different applications.

Abstract: The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating virus infection in the respiratory tract and virus transmission through the respiratory tract. In particular, the presently-disclosed subject matter relates to inhibiting and treating virus infection in a subject using compositions and antibodies that trap viruses in mucus of the respiratory tract, thereby inhibiting transport of virus across or through mucus secretions.

Abstract: The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating virus infection in the respiratory tract and virus transmission through the respiratory tract. In particular, the presently-disclosed subject matter relates to inhibiting and treating virus infection in a subject using compositions and antibodies that trap viruses in mucus of the respiratory tract, thereby inhibiting transport of virus across or through mucus secretions.

Abstract: A resin composition that allows production of laminated sheets excellent in heat resistance and processability is disclosed. The resin composition comprises: a) a block copolymer, where the block copolymer comprises at least one polymer block comprising polymerized acyclic conjugated diene units, such as butadiene units, and at least one polymer block containing units like a conjugated cyclic diene such as 1,3-cyclohexadiene or monomer units characterized by unit Tg above 100° C.

Abstract: A semiconductor device and a method for fabricating the semiconductor device are provided, in which the method includes the steps of forming a gate structure on a substrate, forming a spacer on a sidewall of the gate structure, forming two recesses adjacent to two sides of the spacer, performing a cleaning process to trim the spacer for forming a void between the spacer and the substrate, and forming two portions of an epitaxial layer in the two recesses. The semiconductor device preferably includes a cap layer on the two portions of the epitaxial layer as the cap layer includes a planar top surface and an inclined sidewall.

Abstract: A nitride-based semiconductor device includes a patterned substrate having an etched surface that is formed with a plurality of protrusions, an aluminum nitride (AlN)-based film disposed on the etched surface, and a nitride-based semiconductor stacked structure disposed on the aluminum nitride-based film. Each of the protrusions has a side face. The AlN-based film includes a plurality of crystal defects formed on the side face of each protrusion. Each of the crystal defects has a width of smaller than 20 nm and/or the number of the crystal defects that are formed on the side face of each protrusion and that have a width of greater than 10 nm is less than 10. A method for preparing the semiconductor device is also disclosed.

Abstract: A method of detecting the presence of a prostate cancer in a human subject comprising the steps of (a) obtaining a histologically normal prostate tissue sample from the patient and (b) quantifying the epithelial thickness or gland lumen roundness of the tissue, wherein an increase in epithelial thickness or a decrease in gland lumen roundness indicates the presence of prostate cancer or a prostate cancer field defect.

Abstract: Aspects provide multi-tier data synchronization based on a concurrent linked monitor list. A computer processor associates each of different data regions of a packed data object with different mutual exclusion monitor nodes of a linked list, the data regions defined by a data offset location within memory data and a length of the data region from the offset. In response to determining that a first data region of the packed data object is on-heap memory, the processor associates the first data region with a container representative of the linked list sorted in ascending order of the respective offset values, and a hash code of the container; and in response to determining that a second data region of the packed data object is off-heap memory, stores container information for the second data region in the linked list and resorts the linked-list nodes of container information in ascending order of offset values.

Abstract: A method for displaying an on-screen keyboard is applied a computing device connected to a physical keyboard and a screen, where the physical keyboard includes a plurality of keycaps capable of responding to a touch on the keycap to output a first key signal and responding to a keystroke on the keycap to output a second key signal to the computing device, and the method for displaying an on-screen keyboard includes: displaying an on-screen keyboard on a topmost layer of a display image of the screen; reading the first key signal output by the physical keyboard corresponding to the touch on the keycap; and displaying, according to the first key signal, a first key mark at a position corresponding to the touched keycap on the on-screen keyboard.

Abstract: A method of detecting the presence of a prostate cancer in a human subject comprising the steps of (a) obtaining a histologically normal prostate tissue sample from the patient and (b) quantifying the epithelial percentage of the tissue, wherein an epithelial percentage greater than 39% indicates the presence of prostate cancer or a prostate cancer field defect.