Abstract: A suspension formulation of an insulinotropic peptide (e.g., glucagon-like peptide-1 (GLP-1) or exenatide) is described. The suspension formulation comprises (i) a non-aqueous, single-phase vehicle, comprising one or more polymer and one or more one solvent, wherein the vehicle exhibits viscous fluid characteristics, and (ii) a particle formulation comprising the insulinotropic peptide, wherein the peptide is dispersed in the vehicle. The particle formulation further includes a stabilizing component comprising one or more stabilizers, for example, carbohydrates, antioxidants, amino acids, and buffers. Devices for delivering the suspension formulations and methods of use are also described.

Abstract: Disclosed are a method and a device for controlling flow of liquid zinc (2) in a zinc pot (1) for hot-dip galvanization. Under the blowing effects of an air knife above the zinc pot (1) for hot-dip galvanization onto strip steel (3), the liquid zinc (2) diffuses and flows outwards to zones (zones I, II, III and IV) comprising the left side, the right side, the front end of the zinc pot, respectively, and a zone between the strip steel (3) and a furnace snout (4), and surface dross rapidly generated on the surface of the liquid zinc (2) is driven to flow outwards to the zones (zones I, II, III and IV). On edge sides of the zones (zones I, II, III and IV), travelling magnetic field generators (71, 72, 73, 74, 75, 76, 77, 78, 712, 756) are arranged in multiple sections above the surface of the liquid zinc (2) in the zinc pot (1), so as to excite a travelling magnetic field to generate an electromagnetic driving force on the liquid zinc (2) to drive the flow of the liquid zinc (2).

Abstract: A display method of an on-screen keyboard, applied to a computing device connected to a physical keyboard, a screen and a sensor, the physical keyboard including a plurality of keys, and the sensor being configured to detect and obtain an operating position image, where the display method of the on-screen keyboard includes: displaying an on-screen keyboard at a topmost layer of a displayed image of the screen; reading the operating position image obtained by the sensor; converting the operating position image into an operating position data, where the operating position data includes relative position data of a key which is touched or is approached; and according to the operating position data, displaying a first key mark at a position corresponding to the key which is touched or is approached on the on-screen keyboard.

Abstract: A bridge-type circuit comprises a H-bridge switch module and a buffering and reclosing module. The H-bridge switch module comprises four power semiconductor switch devices. Every two of the four power semiconductor switch devices are connected in series in the same direction to form a bridge arm, and the two bridge arms are further connected in parallel. Middle points of the two bridge arms respectively serve as an input terminal and an output terminal. The buffering and reclosing module is connected in parallel with the two bridge arms of the full bridge module. Also provided are a direct current breaking device formed by connecting the above bridge-type circuits in cascade and a control method thereof. The direct current breaking device is provided with the buffering and reclosing module, such that line voltage fluctuation generated during a reclosing operation is small.

Abstract: The present invention relates to osmotic delivery devices, formulations, and methods for delivery of two or more beneficial agents. In one aspect, the present invention provides osmotic delivery devices useful for substantially concurrent administration of two or more beneficial agents. In another aspect, the present invention provides beneficial agent formulations for use in the osmotic delivery devices. The formulations include formulations wherein beneficial agents are soluble in the vehicle, suspension formulations comprising particle formulations of one or more beneficial agent, and combinations thereof. Further, methods for treatment of a variety of diseases or conditions using two or more beneficial agents are disclosed, wherein the methods are preferably practiced using the osmotic delivery devices and/or formulations of the invention.

Abstract: A nitride-based semiconductor device includes a patterned substrate having an etched surface that is formed with a plurality of protrusions, an aluminum nitride (AlN)-based film disposed on the etched surface, and a nitride-based semiconductor stacked structure disposed on the aluminum nitride-based film. Each of the protrusions has a side face. The AlN-based film includes a plurality of crystal defects formed on the side face of each protrusion. Each of the crystal defects has a width of smaller than 20 nm and/or the number of the crystal defects that are formed on the side face of each protrusion and that have a width of greater than 10 nm is less than 10. A method for preparing the semiconductor device is also disclosed.

Abstract: A direct current switch-off device comprises an on-state current branch circuit and a current commutating and breaking unit which are connected in parallel. The on-state current branch circuit has a mechanical switch (S) and a current transfer module which are connected in series. The current commutating and breaking unit comprises a bridge-type branch circuit and a current-breaking branch circuit. The current-breaking branch circuit and two bridge arms of the bridge-type branch circuit are connected in parallel. The current-breaking branch circuit comprises a nonlinear resistor (RI) and a valve group consisting of fully-controlled devices connected in series. The nonlinear resistor (RI) and the valve group are connected in parallel. Two ends of each fully-controlled device in the valve group are connected in parallel with a buffering and reclosing circuit.

Abstract: A fast return method for CSFB user equipment, includes: receiving a trigger message sent by a mobile switching center MSC, where the trigger message is used to trigger release of a circuit switched CS service of CSFB user equipment UE, and the UE runs both the CS service and a packet switched PS service; and sending a radio resource control RRC connection release message to the UE according to the trigger message, so as to trigger the UE to release a radio bearer of the CS service, a radio bearer of the PS service, and an RRC connection according to the RRC connection release message and fast return to a Long Term Evolution LTE network. According to embodiments of the present invention, a delay for the CSFB user equipment to return to the LTE network can be reduced, thereby improving user experience.

Abstract: A suspension formulation of an insulinotropic peptide (e.g., glucagon-like peptide-1 (GLP-1) or exenatide) is described. The suspension formulation comprises (i) a non-aqueous, single-phase vehicle, comprising one or more polymer and one or more one solvent, wherein the vehicle exhibits viscous fluid characteristics, and (ii) a particle formulation comprising the insulinotropic peptide, wherein the peptide is dispersed in the vehicle. The particle formulation further includes a stabilizing component comprising one or more stabilizers, for example, carbohydrates, antioxidants, amino acids, and buffers. Devices for delivering the suspension formulations and methods of use are also described.

Abstract: A keyboard gesture instruction generating method includes: loading an instruction condition definition table, where the instruction condition definition table includes a plurality of gesture instructions, and each gesture instruction includes a plurality of instruction conditions, and each instruction condition has a corresponding defined value; reading an operating position image obtained by a sensor; converting the operating position image into an operating position data, where the operating position data includes relative position data of keys which are referenced; recognizing a gesture event according to multiple sets of the successive operating position data; obtaining a plurality of detected values of the gesture event and comparing the detected values with these defined values; if these detected values match with the defined values of all the instruction conditions of one of the gesture instructions, stopping tracking of the gesture event; and executing the matching gesture instruction.

Abstract: A keyboard device includes a base, a plurality of keys, a light source module, a first sensor, a second sensor, and a control module. An ambient luminance of the plurality of keys is detected by using the first sensor. When the ambient luminance is less than an ambient luminance at which the second sensor can capture a required image, the control module turns on the light source module to provide a light source for the plurality of keys to improve the ambient luminance, so that the second sensor to can clearly capture the required image and obtain the required data by means of analysis.

Abstract: A method for generating a touch control instruction, includes: loading an instruction condition definition table, where the instruction condition definition table includes a plurality of touch control instructions, and each touch control instruction includes a plurality of instruction conditions and definition values corresponding to the instruction conditions; reading a first key signal output by a physical keyboard corresponding to a touch on a keycap; recognizing a touch control event according to multiple consecutive first key signals; obtaining a plurality of detection values of the touch control event and comparing the detection values with the definition values; if the detection values match definition values of all instruction conditions of a touch control instruction, stopping tracing of the touch control event; and executing the matched touch control instruction.

Abstract: Implementation manners of the present invention disclose a data processing method and system, a terminal, and a server, where the data processing method includes: acquiring a service processing instruction inputted by a user; generating a service processing request according to the service processing instruction, where the service processing request includes a unique identifier of the terminal; and sending the service processing request to a server, so that the server queries, according to the unique identifier of the terminal in the service processing request, an on-sale data maintenance list for product information corresponding to the unique identifier of the terminal; and processing, according to the product information corresponding to the unique identifier of the terminal, a service requested by the service processing request. The technical solutions disclosed by the present invention require no complex manual operations, thereby decreasing an error rate, improving a service processing speed.

Abstract: A closing control method for a high-voltage DC circuit breaker. The method comprises: closing breaking units of the transfer branch (2) group by group, then closing the main branch (1), and finally open the transfer branch. During the process of closing the breaking units of the transfer branch group by group, determine whether there is a fault in the power transmission system after closing current breaking unit group. if there is no fault, proceed to close the next breaking unit group until all breaking unit groups are closed before proceeding to the next step; if there is a fault, all the breaking units that have been closed are opened and the closing operation is ended. The method can pre-charge the power transmission system during the closing process of the high-voltage DC circuit breaker, and lower the overvoltage and system oscillation caused by the closing operation.

Abstract: A manipulation apparatus includes a body, a connection cable, a connector, and a flexible conduit. The body includes a control element, buttons, and a directional control lever. The control element is in the body and is configured to receive a control signal generated by the buttons and the directional control lever. The buttons are at a first side of the body, and the directional control lever is at a second side of the body. The connection cable is connected to the control element. The connection cable includes a first end and a second end, and the first end is connected to a third side of the body. The connector is connected to the second end of the connection cable. A flexible conduit is outside the connection cable in a sleeve manner, where the flexible conduit extends from the first end of the connection cable to the second end.

Abstract: An isolated anti-SCUBE2 (Signal peptide-complement protein Clr/CIs, Uegf: and Bmp 1 (CUB)-epidermal growth factor (EGF) domain-containing protein 2) antibody or a binding fragment thereof is disclosed. The anti-SCUBE2 antibody comprises an antigen binding region that specifically hinds to a target domain located within SCUBE2 (SEQ ID NO: 66) and exhibits a property of inhibiting vascular endothelial growth factor (VEGF)-induced angiogenesis. The target domain is selected from the group consisting of the EGF-like motifs 4 to 6 ranging from a.a. position 175 to 323, or the spacer region ranging from a.a. position 441 to 659, or the first cys-rich motif ranging from a.a. position 668 to 725 of SCUBE2 (SEQ ID NO: 66). The anti-SCUBE2 antibody or binding fragment thereof is for use in treating a disease associated with VEGF-induced angiogenesis, or in treating a tumor or inhibiting tumor angiogenesis and cancer cell growth in a subject in need thereof.

Abstract: Methods of administering an oligonucleotide of interest into a cell in vitro or in vivo are described. In the methods, a small organic compound active agent is concurrently administered to the cell in an amount effective to increase the delivery of the oligonucleotide into the cell, and/or increase the activity of said oligonucleotide in the cell. Compositions useful for carrying out the method are also described.

Abstract: A bridge-type circuit comprises a H-bridge switch module and a buffering and reclosing module. The H-bridge switch module comprises four power semiconductor switch devices. Every two of the four power semiconductor switch devices are connected in series in the same direction to form a bridge arm, and the two bridge arms are further connected in parallel. Middle points of the two bridge arms respectively serve as an input terminal and an output terminal. The buffering and reclosing module is connected in parallel with the two bridge arms of the full bridge module. Also provided are a direct current breaking device formed by connecting the above bridge-type circuits in cascade and a control method thereof. The direct current breaking device is provided with the buffering and reclosing module, such that line voltage fluctuation generated during a reclosing operation is small.