Abstract: The invention provides a resin-coated optical fiber, including at least: a glass optical fiber composed of a core and a clad for coating the core; a primary layer made of UV-curing resin in contact with the glass optical fiber; and a secondary layer made of the UV-curing resin disposed on an outer periphery of the primary layer, wherein the primary layer has a two-layer structure of an inner layer in contact with a surface of the clad, and an outer layer for coating the inner layer, wherein the UV-curing resin of the inner layer has a Young's modulus of 0.9 MPa or more and 3.0 MPa or less at room temperature in a film state based on JIS standard K7113, and the UV-curing resin of the outer layer has a Young's modulus of 0.1 MPa or more and 0.7 MPa or less at room temperature in a film state based on JIS standard K7113.

Abstract: A multicore fiber includes cores located at vertexes of a polygonal ring and a cladding including sub medium regions and covering the cores. A refractive index of the cladding is lower than a refractive index of the cores and higher than a refractive index of the sub medium regions. The sub medium regions are arranged at positions to reduce a crosstalk between adjacent cores of the cores.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: An optical fiber which, at an optical fiber connecting end having a plurality of voids around the periphery of a core, has a light-permeable substance, such as a resin or glass whose refractive index is lower than that of quartz type substances, filled in the voids adjacent to the connecting end. An optical fiber connecting section where an optical fiber having a plurality of voids in a clad around the periphery of a core is connected to another optical fiber, wherein the optical fiber is connected end-to-end to aforesaid another optical fiber through a refractive index matching agent whose refractive index at the minimum temperature in actual use is lower than that of the core.

Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.

Abstract: A multicore fiber includes cores located at vertexes of a polygonal ring and a cladding including sub medium regions and covering the cores. A refractive index of the cladding is lower than a refractive index of the cores and higher than a refractive index of the sub medium regions. The sub medium regions are arranged at positions to reduce a crosstalk between adjacent cores of the cores.

Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.

Abstract: There is provided a resin coated optical fiber, comprising at least: a glass optical fiber composed of a core and a clad for coating the core; a primary layer made of UV-curing resin in contact with the glass optical fiber; and a secondary layer made of the UV-curing resin disposed on an outer periphery of the primary layer, wherein the primary layer has a two-layer structure of an inner layer in contact with a surface of the clad, and an outer layer for coating the inner layer, wherein the UV-curing resin of the inner layer has Young's modulus of 0.9 MPa or more and 3.0 MPa or less at room temperature in a film state based on JIS standard K7113, and the UV-curing resin of the outer layer has Young's modulus of 0.1 MPa or more and 0.7 MPa or less at room temperature in a film state based on JIS standard K7113.

Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: An optical fiber comprising: a core formed in a center axis area; an inner clad layer, disposed around the core, having a refractive index smaller than that of the core; a pore layer, disposed around the inner clad layer, having a plurality of elongated pores; and an outer clad layer, disposed around the pore layer, having a refractive index equal to or smaller than the refractive index of the core, wherein a length of the elongated pores is not larger than 200 m.

Abstract: An optical fiber laser, according to the present invention, has an optical fiber including a core to which a rare earth element is added and a clad disposed around the core, and also has an excitation light source for emitting excitation light incident on a side of the optical fiber. The optical fiber has a corrugated shape on the outer circumference of the clad along the longitudinal direction thereof; and the optical fiber is wound in a spiral form and is bundled in such a way that adjacent sides of the clad are brought into contact with one another.

Abstract: The optical fiber 1 for an optical fiber laser is provided with a rare earth element doped core 2 doped with a rare earth element, and a cladding 3 formed at an outer periphery of the rare earth element doped core 2. In the optical fiber 1 for an optical fiber laser, the rare earth element doped core 2 is divided into a plurality of core regions 2a, 2b, . . . , 2n?1, 2n along a longitudinal direction of the optical fiber 1 and dopant concentrations of the rare earth element in respective core regions 2a, 2b, . . . , 2n?1, 2n are different from each other, in order to flatten a temperature distribution of the optical fiber 1 along the longitudinal direction.

Abstract: Provided are compounds of Formula V and pharmaceutically acceptable salts thereof which may be useful for the treatment of cancer or other proliferative disorders.

Abstract: To provide a low-cost, high reliability and high-powered operation enabled optical fiber laser, in the optical fiber laser for oscillating a laser light by introducing an excitation light for exciting the rare earth elements into the optical fiber doped partially by the rare earth elements, the optical fiber is wrapped around the base member, and one part of the outer circumferential area of the wrapped optical fiber is processed in order to form a flat surface, and one face of the prism is made contacted to the flat surface, and the excitation light is introduced to another surface of the prism.

Abstract: A semiconductor structure for high voltage/high current MOS circuits is provided, including a deep N-well (NMD), a P-well (PW) disposed within NWD, a plurality of field oxide regions (FOX), a plurality of doping regions, including both N+ regions and P+ regions, disposed within NWD and PW, a gate (G) connected to a doping region, a bulk pad (B) connected to a doping regions, a source pad (S) connected to a doping regions and a drain pad (D) connected to a doping region. The top view of the present invention shows that the regions are of non-specific shapes and overlaid in a radial manner, with doping region connected to B being encompassed by doping region connected to S, which in turn encompassed by G, encompassed by FOX, encompassed by doping region connected to D.