Abstract: The present invention relates to processes of preparing PD-1/PD-L1 inhibitor (R)-1-((7-cyano-2-(3?-(3-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-1,7-naphthyridin-8-ylamino)-2,2?-dimethylbiphenyl-3-yl)benzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid, or salts thereof, related synthetic intermediates, and salts of the intermediates, where the PD-1/PD-L1 inhibitor is useful in the treatment of various diseases including infectious diseases and cancer.

Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.

Abstract: Provided are compositions comprising polynucleotides encoding BG1 polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides, and plants, plant cells, seed, grain comprising a BG1 polypeptide. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for increasing BG1 level in a plant and methods for increasing yield of a plant, nutrient utilization efficiency and/or drought tolerance, are also provided herein.

Abstract: An improved method and system for treating flue gases from a natural gas furnace are provided. The method and system include an acidic gas trap (AGT) adsorber which enables the continuous adsorption and storage of SOx, NOx redox, and formic acid/CO/HC/CH4 oxidation, with a negligible pressure drop. The AGT adsorber includes a catalyst coating having a nanotube structure (e.g., a uniform nanostructure forest coating) or a uniform porous nanostructure of various low-cost oxides through scalable low temperature solution processes, including oxides of Ti, Cu, Ba, Mn, Zr, Zn, Sr, Ca, Li, K, Na, Al, or Ce.

Abstract: Disclosed herein are systems, methods, and devices for detecting traffic lane violations. In one embodiment, a method for detecting a potential traffic violation is disclosed comprising bounding a vehicle detected from one or more video frames of a video in a vehicle bounding box. The vehicle can be detected and bounded using a first convolutional neural network. The method can also comprise bounding, using the one or more processors of the edge device, a plurality of lanes of a roadway detected from the one or more video frames in a plurality of polygons. The plurality of lanes can be detected and bounded using multiple heads of a multi-headed second convolutional neural network. The method can further comprise detecting a potential traffic violation based in part on an overlap of at least part of the vehicle bounding box and at least part of one of the polygons.

Abstract: The present invention relates to processes of preparing PD-1/PD-L1 inhibitor (R)-1-((7-cyano-2-(3?-(3-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-1,7-naphthyridin-8-ylamino)-2,2?-dimethylbiphenyl-3-yl)benzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid, or salts thereof, related synthetic intermediates, and salts of the intermediates, where the PD-1/PD-L1 inhibitor is useful in the treatment of various diseases including infectious diseases and cancer.

Abstract: Disclosed herein are systems and methods for managing traffic rules. In one embodiment, a method of managing traffic rules can comprise generating or updating a semantic map layer based in part on positioning data obtained from one or more edge devices and videos captured by the one or more edge devices. The method can also comprise generating or updating a traffic enforcement layer on top of the semantic map layer. A plurality of traffic rules can be saved as part of the traffic enforcement layer. The method can further comprise generating or updating a traffic insight layer based in part on traffic violations or traffic conditions determined by the one or more edge devices or the server. The traffic insight layer can adjust or provide a suggestion to adjust at least one of the traffic rules based on an impact analysis conducted by the traffic insight layer concerning the traffic rule.

Abstract: Disclosed are systems and methods for detecting traffic violations using one or more mobile detection devices. Videos captured by one or more mobile detection devices can be processed on the mobile detection devices to extract data and information concerning a potential traffic violation involving a vehicle and a restricted road area. The mobile detection devices can transmit such data and information to a server configured to make a determination as to whether a traffic violation has occurred by comparing the data and information received from the mobile detection devices.

Abstract: Disclosed herein are methods and systems for managing traffic violation or enforcement data using a distributed ledger. The distributed ledger provides a transparent chain of custody/evidence related to all digital interactions with traffic violation or enforcement data. The distributed ledger can be audited for data accuracy and integrity by nodes making up the system each time one of the nodes interacts with the traffic violation or enforcement data. For example, a digital evidence package related to a traffic violation event can be generated by a node within the system and a package digest can be logged in the distributed ledger beginning with the creation of the digital evidence package and each time that the digital evidence package is processed, modified, or reviewed by nodes within the system.

Abstract: Disclosed herein are methods and systems for managing traffic violation or enforcement data using a distributed ledger. The distributed ledger provides a transparent chain of custody/evidence related to all digital interactions with traffic violation or enforcement data. The distributed ledger can be audited for data accuracy and integrity by nodes making up the system each time one of the nodes interacts with the traffic violation or enforcement data. For example, a digital evidence package related to a traffic violation event can be generated by a node within the system and a package digest can be logged in the distributed ledger beginning with the creation of the digital evidence package and each time that the digital evidence package is processed, modified, or reviewed by nodes within the system.

Abstract: Disclosed herein are methods and systems for managing traffic violation or enforcement data using a distributed ledger. The distributed ledger provides a transparent chain of custody/evidence related to all digital interactions with traffic violation or enforcement data. The distributed ledger can be audited for data accuracy and integrity by nodes making up the system each time one of the nodes interacts with the traffic violation or enforcement data. For example, a digital evidence package related to a traffic violation event can be generated by a node within the system and a package digest can be logged in the distributed ledger beginning with the creation of the digital evidence package and each time that the digital evidence package is processed, modified, or reviewed by nodes within the system.

Abstract: Soybean plants and soybean seeds comprise increased amounts of essential amino acids such as methionine, tryptophan or lysine. Soybean plants, soybean seeds and soy protein compositions comprising a modified glycinin protein, modified amounts of glycinin and beta-conglycinin, or both have increases in one or more essential amino acids. Protein compositions having increased essential amino acids can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions having increased amounts of essential amino acids are disclosed.

Abstract: Provided are compositions comprising polynucleotides encoding modified MFT polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, and grain comprising the polynucleotides. Additionally, methods using the polynucleotides in plants to increase seed oil and/or protein content are also provided herein.

Abstract: Provided is a method for producing plants having seeds with an increased protein and/or oil content using mutagenesis and non-destructive chemical analysis. Additionally, provided are methods for identifying causative mutations associated with increased protein and/or oil content and methods of generating plants having the causative mutations associated with increased protein and/or oil content.

Abstract: Disclosed herein are systems, methods, and devices for detecting traffic lane violations. In one embodiment, a method for detecting a potential traffic violation is disclosed comprising bounding a vehicle detected from one or more video frames of a video in a vehicle bounding box. The vehicle can be detected and bounded using a first convolutional neural network. The method can also comprise bounding, using the one or more processors of the edge device, a plurality of lanes of a roadway detected from the one or more video frames in a plurality of polygons. The plurality of lanes can be detected and bounded using multiple heads of a multi-headed second convolutional neural network. The method can further comprise detecting a potential traffic violation based in part on an overlap of at least part of the vehicle bounding box and at least part of one of the polygons.

Abstract: Disclosed are systems and methods for detecting traffic violations using one or more mobile detection devices. Videos captured by one or more mobile detection devices can be processed on the mobile detection devices to extract data and information concerning a potential traffic violation involving a vehicle and a restricted road area. The mobile detection devices can transmit such data and information to a server configured to make a determination as to whether a traffic violation has occurred by comparing the data and information received from the mobile detection devices.

Abstract: A method for dynamically managing power consumption, as well as a wake-up method, is disclosed for a wireless weighing platform. The method is initialized by setting both light and deep sleep period, entering a normal operating state, and starting light sleep timing. As long as no weighing operation is detected and the light sleep period has not expired, the method seeks to detect the weighing operation. If the light sleep period expires with no weighing operation, a light sleep state is entered, by turning off a communication function and starting timing for the deep sleep period. If no weighing is when the deep sleep period has expired, the wireless weighing platform enters a deep sleep state, by turning off power supply other than that for an acceleration sensor. If the acceleration sensor detects an effective vibration while in the deep sleep state, the normal operating state is restarted.

Abstract: A computer-implemented method, system and computer program product for accurately identifying an execution time of a performance test. Network latency data is grouped into clustered groups of network latency data. Furthermore, the performance test execution times for the same group of performance tests run in the local and remote cluster environments are obtained. The test execution times impacted by network latency (compensation times) are then determined based on such obtained performance test execution times in the local and remote cluster environments. Such compensation times are then grouped into clustered groups of compensation times. A regression model is built to predict a performance test execution time impacted by network latency (compensation time) using the clustered groups of network latency data and compensation times.

Abstract: Provided are compositions comprising polynucleotides encoding modified diacylglycerol acyltransferase-1 (DGAT1) polypeptides having improved properties, such as increased enzymatic activity and/or increased stability. Plants, plant cells, seed, grain and comprising the polynucleotides are provided which have one or more of increased fatty acid or protein content. Methods of generating the polynucleotides in plant cells include transformation and genetic modification. Methods of employing the polynucleotides in plants, methods for increasing DGAT1 activity in a plant, and methods for increasing fatty acid content or protein content in a plant are provided.

Abstract: Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.