Abstract: A media content distribution service identifies a type of media device sending a request to the service over a network and to dynamically adapt content requested by the media device based on the identification. A request sent by a media device may, for example, identify a media content item a user desires to view at the media device, specify a search query for media content items, or otherwise request interaction with the service. According an embodiment, a media content distribution service may use information known about an identified media device type to dynamically adapt media content or other requested resources for display by the media device. By dynamically adapting media content and other resources based on an identified media device type, the media content distribution service may provide access to the services that is compatible with a wide range of media devices having varying device specifications and capabilities.

Abstract: The present invention relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR4 enzyme and are useful in the treatment of FGFR4-associated diseases such as cancer.

Abstract: The present disclosure relates to bicyclic heterocycles of Formula (I?), and pharmaceutical compositions of the same, that are inhibitors of the FGFR3 and/or FGFR4 enzyme and are useful in the treatment of FGFR-associated diseases.

Abstract: A multimedia content distribution system creates and distributes content files that contain content that may be viewed or displayed using commonly distributed viewer or player programs. A second portion of the content files may be viewed using specialized viewer or player programs.

Abstract: Approaches, techniques, and mechanisms are disclosed for the secure distribution of media content to devices having minimal or no Internet connectivity. Computing devices referred to herein as “local servers” are strategically deployed at various locations, such as stores and other public locations. Packages of media contents are stored on the local servers, and may be updated using various online and/or offline data transfer techniques. Portable devices may directly connect to the local servers via various types of proximity-based connections, such as by wireless local area networks, by wired connections over Universal Serial Bus cables, or by sharing of removable media such as Secure Digital cards. The local servers may copy their media contents to authorized devices when such connections are established. The contents on a device may be automatically be updated the next time the device connects to one of the local servers, so as to include newly selected and/or available content.

Abstract: The present invention is directed to cyclopropylamine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.

Abstract: Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.

Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.

Abstract: A multi-channel power source includes at least one first power conversion unit, at least one second power conversion unit and a heat dissipation device. The first power conversion unit has a plurality of first subsidiary units. The first subsidiary units are electrically connected with each other. Each of the first subsidiary units has at least one first heating element. The second power conversion unit has a plurality of second subsidiary units. The second subsidiary units are electrically connected with each other. Each of the second subsidiary units has at least one second heating element. The heat dissipation device is configured to dissipate a heat generated by the first heating elements and the second heating elements along at least one heat dissipation medium direction. The first subsidiary units and the second subsidiary units are arranged in an at least partially staggered manner along the heat dissipation medium direction.

Abstract: The present invention is directed to cyclopropylamine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.

Abstract: A synchronous rectification module includes a transformer, a first conducting member and a synchronous rectification unit. The transformer includes plural secondary winding assemblies. The outlet ends of the secondary winding assemblies are protruded out from a first lateral region and a second lateral region of the transformer. The first conducting member is located at a third lateral region of the transformer. The synchronous rectification unit includes a first circuit board and a second circuit board. The first circuit board is connected with the first conducting member and located at the first lateral region. The second circuit board is connected with the first conducting member and located at the second lateral region. The outlet ends of the secondary winding assemblies are penetrated through corresponding first insertion holes of the first circuit board and corresponding second insertion holes of the second circuit board.

Abstract: A dryer appliance including an air circulation duct is provided herein. The dryer appliance may also include a cabinet, a drum, an air handler, and a heat exchange section. The air circulation duct may define a recirculation loop with the drum. The air circulation duct may define a drum air inlet upstream from the drum and a drum air outlet downstream from the drum. The air circulation duct may further define a predetermined leakage port in fluid communication between the recirculation loop and the interior volume of the cabinet. The air handler may be disposed along the air circulation duct in fluid communication between the drum air outlet and the drum air inlet. The heat exchange section may be disposed along the air circulation duct in thermal communication with air within the recirculation loop.

Abstract: Disclosed are compounds of Formula (I?), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.

Abstract: The present invention relates to an antimicrobial composition and more particularly an antimicrobial composition for leave-on applications. The present invention discloses an antimicrobial composition comprising; a) 0.01 to 2% by weight of thymol; b) 0.01 to 2% by weight of terpineol; and c) 0.1 to 2% by weight of a cationic phospholipid complex.

Abstract: Approaches, techniques, and mechanisms are disclosed for the collection, distribution, and/or reporting of media content. According to an embodiment, media content items from one or more content providers are ingested into a content distribution system implemented by one or more server computer devices. These items of media content may comprise a variety of constituent elements, such as one or more video data units, one or more audio data units, descriptive metadata, subtitle units, thumbnails, or other information, which may be ingested all at once, or separately over time. Items may be processed using various workflows to refine content item components and/or generate new content items. Various publishing rules may be utilized to determine when the system is ready to publish a content item and distribute the item to client devices. Clients may request content items from various published listings, or search for content items by metadata and/or subtitles.

Abstract: A method for controlling a pipeline-based processor. The method includes determining a change in a workload. The method also includes activating or shutting down, by at least one controller circuit, one or more of the plurality of enhanced pipeline stages based on at least one corresponding enhanced stage priority level of the one or more of the plurality of enhanced pipeline stages and requirements for performance of the workload. The method additionally includes activating or shutting down, by the at least one controller circuit, one or more of the plurality of enhanced modules of the particular pipeline stage based on at least one corresponding priority level of the one or more of the plurality of enhanced modules of the particular pipeline stage and the requirements for the performance of the workload.

Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.

Abstract: The present invention is directed to cyclopropylamine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.

Abstract: Genetic male sterile plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants and methods of use of said plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production.

Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.