Patents by Inventor Boris Mathys

Boris Mathys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridine derivatives
    Patent number: 8178562
    Abstract: The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: May 15, 2012
    Assignee: Actelion Pharmaceuticals, Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Joerg Velker
  • PYRIDIN-4-YL DERIVATIVES
    Publication number: 20120108638
    Abstract: The invention relates to pyridine derivatives of Formula (I), wherein A, R1, R2, R3, and R4 are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: July 15, 2010
    Publication date: May 3, 2012
    Inventors: Martin Bolli, Cyrille Lescop, Boris Mathys, Keith Morrison, Claus Mueller, Oliver Nayler, Beat Steiner
  • Thiophene derivatives as agonists of S1P1/EDG1
    Patent number: 8148410
    Abstract: The invention relates to novel thiophene derivatives (I), their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents. Formula (I).
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: April 3, 2012
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, Cyrille Lescop, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner
  • Thiophene derivatives as S1P1/EDGE1 receptor agonists
    Patent number: 8133910
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: March 13, 2012
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • Phenyl derivatives and their use as immunomodulators
    Patent number: 8044076
    Abstract: The invention relates to phenyl derivatives of formula (I), their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: October 25, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • Hydrogenated benzo (C) thiophene derivatives as immunomodulators
    Patent number: 8039644
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: October 18, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jorg Velker, Thomas Weller
  • PYRIDINE DERIVATIVES AS S1P1/EDG1 RECEPTOR MODULATORS
    Publication number: 20110212998
    Abstract: The invention relates to novel pyridine derivatives of formula (D, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents. Formula (I) wherein A represents and the other substituents are as defined in the claims.
    Type: Application
    Filed: August 14, 2008
    Publication date: September 1, 2011
    Inventors: Martin Bolli, Cyrille Lescop, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • Thiophene derivatives as S1P1/EDG1 receptor agonists
    Patent number: 8003800
    Abstract: The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH?CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the asterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.
    Type: Grant
    Filed: January 10, 2007
    Date of Patent: August 23, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • Thiophene derivatives
    Patent number: 7981924
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: July 19, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • Thiophene derivatives
    Patent number: 7951794
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: June 20, 2006
    Date of Patent: May 31, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Jörg Velker
  • NOVEL PYRIMIDINE-PYRIDINE DERIVATIVES
    Publication number: 20110046170
    Abstract: The invention relates to novel pyrimidine-pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: March 3, 2009
    Publication date: February 24, 2011
    Inventors: Martin Bolli, Gyrille Lescop, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner
  • NOVEL AMINOMETHYL BENZENE DERIVATIVES
    Publication number: 20110028449
    Abstract: The invention relates to novel aminomethyl benzene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: March 3, 2009
    Publication date: February 3, 2011
    Inventors: Martin Bolli, Cyrille Lescop, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner
  • PYRIDINE COMPOUNDS
    Publication number: 20110028448
    Abstract: The invention relates to pyridine compounds, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: March 3, 2009
    Publication date: February 3, 2011
    Inventors: Martin Bolli, Cyrille Lescop, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner
  • Thiazolidin-4-one derivatives
    Patent number: 7875726
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Grant
    Filed: June 3, 2008
    Date of Patent: January 25, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • PYRIDIN-2-YL DERIVATIVES AS IMMUNOMODULATING AGENTS
    Publication number: 20100331372
    Abstract: The invention relates to pyridine derivatives of Formula (I) wherein A, R1, R2, R3, R4, R5, R6 and R7 are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: February 25, 2009
    Publication date: December 30, 2010
    Inventors: Martin Bolli, Cyrille Lescop, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner
  • Thiophene derivatives as spingosine-1-phosphate-1 receptor agonists
    Patent number: 7846964
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: December 7, 2010
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, J{umlaut over ())}{umlaut over (})}org Velker, Thomas Weller
  • THIOPHENE DERIVATIVES AS AGONISTS OF S1P1/EDG1
    Publication number: 20100261702
    Abstract: The invention relates to novel thiophene derivatives (1), their preparation and their use as pharmaceutically active compounds.Said compounds particularly act as immunomodulating agents. Formula (I).
    Type: Application
    Filed: December 9, 2008
    Publication date: October 14, 2010
    Inventors: Martin Bolli, Cyrille Lescop, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner
  • NOVEL THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS
    Publication number: 20100240717
    Abstract: The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH?CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the sterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.
    Type: Application
    Filed: January 10, 2007
    Publication date: September 23, 2010
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Boli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • NOVEL PYRIMIDINE DERIVATIVES
    Publication number: 20100234346
    Abstract: The invention relates to novel pyrimidine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: October 31, 2008
    Publication date: September 16, 2010
    Inventors: Martin Bolli, Cyrille Lescop, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner
  • HYDROGENATED BENZO (C) THIOPHENE DERIVATIVES AS IMMUNOMODULATORS
    Publication number: 20100204198
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: March 29, 2010
    Publication date: August 12, 2010
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jörg Velker, Thomas Weller