Patents by Inventor Boris Mathys

Boris Mathys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinoline derivatives
    Patent number: 7375227
    Abstract: The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: May 20, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jörg Velker, Thomas Weller
  • Novel Thiophene Derivatives
    Publication number: 20080064740
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: July 20, 2005
    Publication date: March 13, 2008
    Applicant: ACTELION PHARMACEUTICALS, LTD.
    Inventors: Martin Bolli, Daniel Bur, Martine Clozel, Walter Fischli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • Novel thiazolidin-4-one derivatives
    Publication number: 20070082933
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Application
    Filed: November 16, 2004
    Publication date: April 12, 2007
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz
  • Novel pyridine derivatives
    Publication number: 20070043081
    Abstract: The invention relates to novel pyridine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: September 21, 2004
    Publication date: February 22, 2007
    Inventors: Daniel Bur, Martine Clozel, Boris Mathys, Claus Mueller, Michael Scherz, Joerg Velker, Thomas Weller
  • Novel piperidine derivatives
    Publication number: 20070010516
    Abstract: The invention relates to novel piperidine derivatives and related compounds of General Formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists, in particular their use as urotensin II antagonists.
    Type: Application
    Filed: May 4, 2004
    Publication date: January 11, 2007
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jorg Velker, Thomas Weller
  • Piperazine-alkyl-ureido derivatives
    Publication number: 20060211707
    Abstract: The invention relates to novel piperazine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: May 4, 2004
    Publication date: September 21, 2006
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jorg Velker, Thomas Weller
  • 1-Pyridin-4-yl-urea derivatives
    Publication number: 20060094716
    Abstract: The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: September 12, 2003
    Publication date: May 4, 2006
    Applicant: Actelion Pharmaceuticals LTD
    Inventors: Hamed Aissaoui, Christoph Binkert, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller, Jorg Welker, Martine Clozel
  • 4-(Piperidyl-and pyrrolidyl-alkyl-ureido)-quinolines as urotensin II receptor antagonists
    Publication number: 20050043535
    Abstract: The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: December 2, 2002
    Publication date: February 24, 2005
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jorg Velker, Thomas Weller
  • 1,2,3,4-tetrahydroisoquinolines derivatives
    Publication number: 20040242564
    Abstract: The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: July 13, 2004
    Publication date: December 2, 2004
    Inventors: Jorg Velker, Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • 1,2,3,4-Tetrahydroisoquinolines derivatives as urotensin II receptor antagonists
    Patent number: 6815451
    Abstract: The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists especially urotensin II antagonists.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: November 9, 2004
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Jörg Velker, Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • 1 2 3 4 Tetrahydroisoquinolines derivatives as urotensin II receptor antagonists
    Publication number: 20040110744
    Abstract: The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists especially urotensin II antagonists.
    Type: Application
    Filed: September 15, 2003
    Publication date: June 10, 2004
    Inventors: Jorg Velker, Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller