Patents by Inventor Boris Mathys

Boris Mathys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridine derivatives
    Patent number: 7750161
    Abstract: The invention relates to novel pyridine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Grant
    Filed: September 21, 2004
    Date of Patent: July 6, 2010
    Inventors: Daniel Bur, Martine Clozel, Boris Mathys, Claus Mueller, Michael Scherz, Joerg Velker, Thomas Weller
  • Thiophene derivatives
    Patent number: 7750040
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: July 6, 2010
    Inventors: Martin Bolli, Daniel Bur, Martine Clozel, Walter Fischli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • Pyridin-3-yl derivatives as immunomodulating agents
    Publication number: 20100168005
    Abstract: The invention relates to pyridin-3-yl derivatives of Formula (I) wherein R1, R2, R3, R4, R5; R6 and A are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: September 6, 2007
    Publication date: July 1, 2010
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner
  • Hydrogenated benzo (C) thiophene derivatives as immunomodulators
    Patent number: 7723378
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds particularly as immunosuppressant agents.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: May 25, 2010
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jörg Velker, Thomas Weller
  • PHENYL DERIVATIVES AND THEIR USE AS IMMUNOMODULATORS
    Publication number: 20100087495
    Abstract: The invention relates to phenyl derivatives of formula (I), their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: July 10, 2007
    Publication date: April 8, 2010
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • AMINO-PYRIDINE DERIVATIVES AS S1P1 /EDG1 RECEPTOR AGONISTS
    Publication number: 20100087417
    Abstract: The invention relates to novel amino-pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: February 29, 2008
    Publication date: April 8, 2010
    Inventors: Martin Bolli, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • NOVEL THIOPHENE DERIVATIVES
    Publication number: 20100075946
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: June 20, 2006
    Publication date: March 25, 2010
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Jörg Velker
  • Pyridin-4-yl derivatives as immunomodulating agents
    Publication number: 20100063108
    Abstract: The invention relates to pyridine derivatives of Formula (I) wherein A, R1, R2, R3, R4, R5, and R6 are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: September 6, 2007
    Publication date: March 11, 2010
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • Thiophene derivatives as S1P1/EDGE1 receptor agonists
    Publication number: 20100048648
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: July 10, 2007
    Publication date: February 25, 2010
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • Thiazolidin-4-one derivatives
    Patent number: 7626037
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: December 1, 2009
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • NOVEL THIAZOLIDIN 4-ONE DERIVATIVES
    Publication number: 20090275625
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Application
    Filed: July 2, 2009
    Publication date: November 5, 2009
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • Thiophene derivatives as Sphingosine-1-phosphate-1 receptor agonists
    Patent number: 7605269
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: October 20, 2009
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jörg Velker, Thomas Weller
  • Novel Pyridine Derivatives
    Publication number: 20090005421
    Abstract: The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: January 23, 2007
    Publication date: January 1, 2009
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • Novel Thiophene Derivatives as Sphingosine-1-Phosphate-1 Receptor Agonists
    Publication number: 20080318955
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: March 20, 2006
    Publication date: December 25, 2008
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jorg Velker, Thomas Weller
  • Novel Thiophene Derivatives
    Publication number: 20080300294
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: November 22, 2006
    Publication date: December 4, 2008
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • NOVEL THIAZOLIDIN-4-ONE DERIVATIVES
    Publication number: 20080280962
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Application
    Filed: June 3, 2008
    Publication date: November 13, 2008
    Applicant: ACTELION PHARMACEUTICALS, LTD.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • Thiazolidin-4-one derivatives
    Patent number: 7435828
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4- one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: October 14, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • Novel Thiophene Derivatives as Spingosine-1-Phosphate-1 Receptor Agonists
    Publication number: 20080194670
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: March 20, 2006
    Publication date: August 14, 2008
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jorg Velker, Thomas Weller
  • Hydrogenated Benzo (C) Thiophene Derivatives as Immunomodulators
    Publication number: 20080176926
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: March 20, 2006
    Publication date: July 24, 2008
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jorg Velker, Thomas Weller
  • NOVEL THIAZOLIDIN-4-ONE DERIVATIVES
    Publication number: 20080146629
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Application
    Filed: February 5, 2008
    Publication date: June 19, 2008
    Applicant: ACTELION PHARMACEUTICALS, LTD.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler