Abstract: A gantry crane adapter for a two-post lift includes a pair of angle brackets, each of which has a first, horizontal leg and second, vertical leg. The first leg includes an aperture, and a short hook extends in parallel, spaced relation along an outer surface of the second leg. The hook of each bracket is received in the slot in a carriage in a respective post of the two-post lift to removably connect each bracket to the respective carriage, with the first, horizontal legs of the respective brackets projecting toward each other. A load bearing beam is positioned across the brackets such that an internally threaded boss at each end of the beam is received in an aperture in a respective bracket, and a bolt with a washer is threaded down into the boss, to support and retain the load bearing beam across the angle brackets.

Abstract: The disclosure relates to modified orthopoxvirus vectors, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified orthopoxvirus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences and safety. The viruses we have discovered are also amenable to large scale manufacturing protocols.

Abstract: A GUI is used to schedule a set of tasks for one or more robots to test samples using one or more instruments. A set of drivers are used to map instructions for the robots and instruments form a standardized format to a set of instrument/robot-specific formats. Using the standardized formats enables support for new types of robot and/or instrument to be easily added to the system. The robots and instruments generate test results from samples according to the instructions. Information about the testing may be stored in conjunction with user identifiers and other metadata to provide a verifiable audit trail across the instruments and robots.

Abstract: Methods, systems, and use cases for one-touch inline cryptographic data security are discussed, including an edge computing device with a network communications circuitry (NCC), an enhanced DMA engine coupled to a memory device and including a cryptographic engine, and processing circuitry configured to perform a secure exchange with a second edge computing device to negotiate a shared symmetric encryption key, based on a request for data. An inline encryption command for communication to the enhanced DMA engine is generated. The inline encryption command includes a first address associated with a storage location storing the data, a second address associated with a memory location in the memory device, and the shared symmetric encryption key. The data is retrieved from the storage location using the first address, the data is encrypted using the shared symmetric encryption key, and the encrypted data is stored in the memory location using the second address.

Abstract: Apparatus and methods for managing pain uses a multiplexed modulation/stimulation signal to provide pain relief during spinal cord stimulation or peripheral nerve stimulation.

Abstract: Vapor-permeable, substantially water-impermeable, corrosion-inhibiting composites are disclosed herein. For instance, disclosed herein are composites comprising a first layer comprising a first nonwoven; and a second layer adjacent to and mechanically integrated with the first layer, the second layer comprising a polymer having a melt flow index of about 10 g/10 mins to about 200 g/10 mins, and a corrosion inhibitor, wherein the composite has a moisture vapor transmission rate of from about 25 g/m2/day to about 1000 g/m2/day when measured at about 23° C. and about 50% relative humidity. Also disclosed herein are methods of making and using the same.

Abstract: A system for selecting a sensitivity level for adjusting an intensity setting for therapy provided to a patient includes one or more processors and one or more processors coupled to the memory. The one or more processors are configured to receive an indication of an input to adjust an intensity setting related to the therapy provided to the patient and determine a sensitivity level for adjustment of the intensity setting based on an efficacy of the therapy provided to the patient. The one or more processors are further configured to determine an updated intensity level for the intensity setting based on the sensitivity level and the input to adjust the intensity setting and output an instruction to cause a medical device to provide the therapy at the updated intensity level.

Abstract: Provided are compounds of Formula (I?) or (I) below, or pharmaceutically acceptable salts thereof, and methods for their use and production.

Abstract: The present disclosure is directed to a shipping container with a corrugated medium that lines an interior pocket of the shipping container as well devices and components (e.g., corrugating rollers, corrugating machines, scoring rollers, and scoring machines) that are utilized to manufacture the shipping containers. The corrugated medium has flutes that cushion, support, and protect a product that is shipped within the shipping container. The corrugated medium may include a first portion with first flutes and a second portion with second flutes that are offset relative to the first flutes. The offset first flutes and second flutes results in peaks of the first flutes nesting within valleys of the second flutes, and peaks of the second flutes nesting within valleys of the first flutes.

Abstract: The invention disclosed herein is directed to compounds of Formula I and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention also comprises pharmaceutical compositions comprising a therapeutically effective amount of compound of Formula I, or a pharmaceutically acceptable salt thereof. The invention disclosed herein is also directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention disclosed herein is further directed to methods of treating prostate, breast, colon, pancreatic, chronic lymphocytic leukemia, melanoma and other cancers comprising administration of a therapeutically effective amount of a selective PPAR? antagonist.

Abstract: Disclosed are compositions, methods and apparatus for diagnosing and/or monitoring a virus-associated systemic inflammation by measurement of a host immune response. The invention can be used for diagnosis including early diagnosis, monitoring, making treatment decisions, or management of subjects suspected of having systemic inflammation associated with an infection. More particularly, the present disclosure relates to peripheral blood RNA and protein biomarkers that are useful for specifically distinguishing between the host systemic immune response to viruses as compared to the host immune response to other causes of systemic inflammation.

Abstract: The present disclosure involves systems, software, and computer implemented methods for presenting information and/or services to a user. One example method includes establishing a user session between a computing device operated by an entity and a first user device operated by a customer of the entity. The first user device provides a first interface through which the customer participates in the user session. The method also includes determining, based at least on a complexity of first information to be provided to the customer, to change the first interface to a new interface. Further, the method includes selecting, based on the complexity of the first information, a new interface, where the new interface is provided by at least a second user device. Furthermore, the method includes implementing the new interface to facilitate for the customer to participate in the user session.

Abstract: Provided herein are systems, methods and computer readable media for classification of documents using a location hierarchy.

Abstract: The present disclosure relates to systems, methods, and computer-readable media for securely verifying an identity of a user of a client device based on a signal transmitted by the client device. For example, systems disclosed herein include registering a client device and facility device via a cloud computing system to enable the client device and facility device to securely communicate a signal via a wireless connection. The systems disclosed herein additionally include determining whether a trigger condition applies based on a position of the client device relative to the facility device. The systems disclosed herein further include maintaining and updating a subset of user verification information to include personal verification of a registered user of the client device. Using the subset of user verification information, a biometric scanning device may efficiently and accurately verify an identity of an individual associated with the client device.

Abstract: Various approaches for implementing platform resource management are described. In an edge computing system deployment, an edge computing device includes processing circuitry coupled to a memory. The processing circuitry is configured to obtain, from an orchestration provider, an SLO (or SLA) that defines usage of an accessible feature of the edge computing device by a container executing on a virtual machine within the edge computing system. A computation model is retrieved based on at least one key performance indicator (KPI) specified in the SLO. The defined usage of the accessible feature is mapped to a plurality of feature controls using the retrieved computation model. The plurality of feature controls is associated with platform resources of the edge computing device that are pre-allocated to the container. The usage of the platform resources allocated to the container is monitored using the plurality of feature controls.

Abstract: The disclosure relates to modified orthopoxvirus vectors, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified orthopoxvirus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences and safety. The viruses we have discovered are also amenable to large scale manufacturing protocols.

Abstract: Systems, methods, and apparatuses for generating and releasing iodine are described. Some embodiments may include a dressing member including a plurality of iodine-forming reagents and a water-swellable material. In some embodiments, the dressing member may include water-swellable fibers. The water-swellable fibers may each include a water-swellable material in which iodine-forming reagents are dispersed. As liquid comes into contact with and is absorbed by the water-swellable material, the iodine-forming reagents may come into contact with each other, causing an iodine-forming reaction to occur, producing iodine.

Abstract: A scrolling shifter assembly having a housing rotatably supporting a scrolling wheel having a knurled exterior edge accessible to a vehicle operator, the scrolling wheel also including an annular side detent profile. A magnet is positioned in proximity to a sensor mounted to a printed circuit board (PCBA) within the housing and displaces relative to the sensor in response to rotation of the scrolling wheel. A display component is mounted in proximity to the PCBA. At least one haptic biasing component including any of spring loaded pawl or wave spring is supported within the housing and biases against the detent profile such that, and upon the operator actuating the scrolling wheel, the pawl is caused to displace relative to the profile in order to incrementally rotate the wheel, the magnet rotating relative to the PCBA sensor to cause an associated processor to electronically instruct a shift change to an engine control unit.