Abstract: A hydraulic manifold assembly having a block including a plurality of fluid ports provided on a common surface of the block, and a set of hydraulic fittings. Each fitting is assigned to a prescribed one of the ports. Each fitting includes a hollow bolt insertable into the prescribed fluid port, and a banjo block having a first aperture for receiving the hollow bolt and a second aperture intersecting the first aperture. The second aperture provides an external fluid port for fluidly coupling a remote device. The plurality of banjo blocks includes at least one adjacent pair of banjo blocks that are unique from each other and have exterior shapes complementary to each other to control the relative orientation therebetween when coupled to the prescribed fluid ports. The exterior shapes of the adjacent banjo blocks cooperate to prevent misassembly.

Abstract: A containment case comprises a composite core, with an inner surface, and at least one ceramic layer integrated with the composite core. The at least one ceramic layer is bonded to the inner surface of the composite core with a resin. In another embodiment, a containment case comprises a composite core, with an inner surface, and a hybrid material comprising at least one ceramic material and at least one non-ceramic material. The hybrid material is disposed on the inner surface of the composite core. The hybrid material is bonded to the inner surface of the composite core with a resin. A method of fabricating a containment case includes the steps of disposing one or more layers of ceramic fabric on an inner surface of a composite core, infusing the composite core and the one or more layers of ceramic fabric with resin, and curing the resin.

Abstract: Systems and methods for lowering levels of carbon dioxide and other atmospheric pollutants are provided. Economically viable systems and processes capable of removing vast quantities of carbon dioxide and other atmospheric pollutants from gaseous waste streams and sequestering them in storage-stable forms are also discussed.

Abstract: Systems and methods for lowering levels of carbon dioxide and other atmospheric pollutants are provided. Economically viable systems and processes capable of removing vast quantities of carbon dioxide and other atmospheric pollutants from gaseous waste streams and sequestering them in storage-stable forms are also discussed.

Abstract: Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins.

Abstract: Provided herein are compounds, compositions and methods for treating disorders mediated by abnormal cellular proliferation and processes for identifying such compounds.

Abstract: Systems and methods are disclosed for generating a proton removing agent and an acidic solution in a low voltage electrochemical system and utilizing the proton removing agent to sequester carbon dioxide from a waste gas in a carbon dioxide sequestration system and utilizing the acidic solution to catalyze at least one step of a chemical syntheses in combination with a plant based material.

Abstract: Methods for making articles having a substantially cylindrical body including providing a substantially cylindrical tool, providing at least one ply of a material, the material being a weave fabric, a non-crimp fabric, or a combination thereof, wrapping the at least one ply of material about the tool to produce an article preform having a plurality of circumferential layers, applying a resin to the article preform, and curing the article preform to produce an article having a substantially cylindrical body.

Abstract: Methods for making a structure having an integral mounting flange involving providing a primary composite structure having a circumference, applying at least one circumferentially oriented core fiber about the circumference of the primary composite structure, applying at least one layer of attachment fibers to operably connect the core fiber to the primary composite structure about the circumference to obtain an integral mounting flange preform, and curing the mounting flange preform to obtain an integral mounting flange.

Abstract: Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of using such cells, and methods to identify compounds related to cell differentiation and development or to treat diseases, using such cells. A mouse model of acute myeloid leukemia (AML) and cells and methods related to such mouse model are also described.

Abstract: This invention generally relates to methods for the production of antibody producing cells and antibodies in protooncogene expressing animals. The invention also relates to methods for the efficient production of antibodies specific for antigens that are normally subject to immunological constraints such as self tolerance. The invention further relates to the production of antibody producing cells and antibodies without the need for the conventional fusing of antibody producing B cells with a myeloma fusion partner.

Abstract: Tethered flange corners including at least one ply of barrier fibers and at least one fiber tow wrapped about the barrier fibers. Also included are flanges having a tethered corner containing at least one ply of barrier fibers, at least one fiber tow wrapped about the barrier fibers, at least one ply of filler fibers applied over the fiber tow, and at least one ply of flange fibers applied over the filler fibers. Additionally included are articles incorporating a composite structure having a flange with a tethered corner containing at least one ply of barrier fibers and at least one fiber tow wrapped about the barrier fibers.

Abstract: Disclosed herein are methods of modulation of the viability of a cell. Further disclosed herein are methods of modulating an immune response. Further disclosed herein are methods of identifying agents capable of modulation of the viability of a cell or an immune response. Further disclosed herein are agents and compositions capable of modulation of the viability of a cell or an immune response.

Abstract: Provided herein are methods for preparing differentiated cells, and the cells prepared by such methods.

Abstract: Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins.

Abstract: A containment case comprises a composite core, with an inner surface, and at least one ceramic layer integrated with the composite core. The at least one ceramic layer is bonded to the inner surface of the composite core with a resin. In another embodiment, a containment case comprises a composite core, with an inner surface, and a hybrid material comprising at least one ceramic material and at least one non-ceramic material. The hybrid material is disposed on the inner surface of the composite core. The hybrid material is bonded to the inner surface of the composite core with a resin. A method of fabricating a containment case includes the steps of disposing one or more layers of ceramic fabric on an inner surface of a composite core, infusing the composite core and the one or more layers of ceramic fabric with resin, and curing the resin.

Abstract: Articles having substantially cylindrical bodies including a plurality of circumferential layers, each layer having at least one ply of material, the material comprising a weave fabric, a non-crimp fabric, or a combination thereof.

Abstract: Methods for making articles having a substantially cylindrical body including providing a substantially cylindrical tool, providing at least one ply of a material, the material being a weave fabric, a non-crimp fabric, or a combination thereof, wrapping the at least one ply of material about the tool to produce an article preform having a plurality of circumferential layers, applying a resin to the article preform, and curing the article preform to produce an article having a substantially cylindrical body.

Abstract: Methods for fabricating a composite structure with a flange having a tethered corner involving providing a composite structure forming tool including a first endplate and a second endplate and having a composite structure formed thereabout, applying at least one ply of barrier fibers about the composite structure adjacent to the first endplate of the composite structure forming tool, and wrapping at least one fiber tow about the barrier fibers.

Abstract: Tethered flange comers including at least one ply of barrier fibers and at least one fiber tow wrapped about the barrier fibers. Also included are flanges having a tethered corner containing at least one ply of barrier fibers, at least one fiber tow wrapped about the barrier fibers, at least one ply of filler fibers applied over the fiber tow, and at least one ply of flange fibers applied over the filler fibers. Additionally included are articles incorporating a composite structure having a flange with a tethered corner containing at least one ply of barrier fibers and at least one fiber tow wrapped about the barrier fibers.