Abstract: Systems, apparatuses, and methods for analyzing information about a user are presented which include obtaining at least one search result based on at least one search terms describing the user; presenting the at least one search result to the user; receiving an indication from the user of the desirability of a search result; and performing an action based on the desirability of the search result. Systems, apparatuses, and methods are also presented for determining a reputation score representing the reputation of a user which include collecting search results from data source, determining an effect on the reputation of the user of the search results from the data source, and calculating a reputation score for the user based on the determined effect on the reputation of the user from the search results from the data source.

Abstract: Described are techniques and mechanisms for enforcing trust between an application and a library loaded by the application. Very generally stated, the application declares one or more trusted code groups (“TCGs”) of which a library must be a member to be authorized for execution with the application. Libraries that are authorized to assert membership in one or more TCGs include a secure indicator of that membership. As the application executes and attempts to load a library, that libraries membership in a TCG authorized by the application is verified prior to loading the library.

Abstract: This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.

Abstract: This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.

Abstract: It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.

Abstract: The present invention relates to a method of detecting biological analytes comprising suspending a target analyte in a suspending solution containing polymeric particles marked with a probe, wherein the probe has an affinity for said target analyte; adding recognition unit-peroxidase conjugate marker to the suspending solution; forming a complex of the target analyte, the polymeric particles marked with a probe, and the recognition unit-peroxidase conjugate marker; contacting a gelatin surface with the suspending solution; adding developer to the suspending solution in contact with the gelatin surface in the presence of phenol to attach the complex to the gelatin surface; washing the gelatin surface; and detecting the complex attached to the gelatin surface.

Abstract: The present invention relates to a method of detecting nucleic acids comprising suspending at least one recognizable target nucleic acid in a suspending solution containing polymeric particles marked with a probe, wherein the probe has an affinity for the target nucleic acid, adding a recognition unit-peroxidase conjugate marker to the suspending solution, forming a complex of the polymeric particles marked with a probe, the target nucleic acid and the recognition unit-peroxidase conjugate marker, contacting the suspending solution with a gelatin surface, adding a developer to the suspending solution in contact with the gelatin surface in the presence of phenol to attach the complex to the gelatin surface, washing the gelatin surface, and detecting the complex attached to the gelatin surface.

Abstract: A system for saving application state history information, containing an historical snap-shot of dynamic application state information associated with execution of a first application on a computing device. The application state history information is saved for use in a subsequent re-launch of the first application.

Abstract: A system for processing user interface actions generated from a user interface device, including generating a freshness status for the user interface action. The freshness status indicates a freshness state associated with the user interface action. The freshness status is associated wit the user interface action.

Abstract: System for dynamic arbitration of a shared resource on a device. A method is provided for arbitrating the allocation of a device resource on a device. The method comprises receiving a request from a requesting application that requests allocation of the device resource, and determining that the device resource is owned by an owning application. The method also comprises associating owner information with requester information to form an arbitration request, wherein the owner information comprises information about the owning application and the requester information comprises information about the requesting application. The method also comprises arbitrating the arbitration request to produce an arbitration decision that indicates whether or not the device resource should be allocated to the requesting application, and allocating the device resource based on the arbitration decision.

Abstract: System for invoking a privileged function in a device. The system includes a method that allows an application to invoke a function on a device, wherein the device includes at least two operating modes comprising a privileged mode and a non-privileged mode, and the function executes in the privileged mode. The method includes receiving a request from the application to invoke the function and determining the operating mode of the application. The method also includes invoking the function using an interrupt, if the application is executing in the non-privileged mode, wherein the function is executed within the same task as the application. The method also includes invoking the function directly, if the application is executing in the privileged mode.

Abstract: Methods are provided for purification of Factor VIII polypeptides by affinity chromatography and ion exchange chromatography, in which the eluate from the affinity column is diluted with a solution comprising higher salt concentration, or lower non-polar agent concentration than that of the elution solution, prior to passing the diluted solution through the ion exchange column. The affinity matrix may comprise a monoclonal antibody or a peptide ligand. The methods result in improved purification without significant yield loss.

Abstract: A frequency offset estimator (400) and corresponding method (600) provides a frequency offset estimate (415) for an OFDM signal. The estimator comprises a data parser (403) coupled to an input signal (401) and arranged to select a group of symbols (305-311) or corresponding samples corresponding to predetermined symbols from the input signal and a processor (405) arranged to provide a correlation corresponding to the symbols, where the correlation corresponds to a frequency offset estimation for the input signal and is determined in a sequential fashion so that the correlation is provided concurrently with the last symbol or sample of the group of symbols to be selected.

Abstract: This invention relates to the application of hydroxyapatite chromatography to the purification of at least one antibody from a preparation containing high molecular weight aggregates. Further, this invention relates to an integration of ceramic hydroxyapatite chromatography into a combination chromatographic protocol for the removal of high molecular weight aggregates from an antibody preparation.

Abstract: System for dynamic registration of privileged mode hooks in a device. The system includes a method for dynamically registering a function in a device that includes at least two operating modes comprising a privileged mode and a non-privileged mode. The method comprises identifying an available slot in a data structure that maps identifiers to functions, and storing a pointer associated with the function in the slot. The method also comprises retrieving an identifier that is associated with the slot, and making the identifier accessible to non-privileged applications.

Abstract: System for providing transitions between operating modes of a device. The system includes a method for providing transitions between a privileged and a non-privileged operating mode. The method comprises executing an application in the non-privileged mode, generating an interrupt to request the services of a privileged function, and transitioning to the privileged mode to execute the privileged function, wherein the privileged function is executed as part of the same thread of execution as the application.

Abstract: System for selectively enabling operating modes of a device. The system includes a method for selectively enabling operating modes of a device during a device initialization, wherein the operating modes comprise a privileged mode and a non-privileged mode. The method includes determining during the device initialization whether the device is to operate in the privileged mode or in both the privileged and non-privileged modes, and enabling the privileged mode if it is determined that the device is to operate only in the privileged mode. The method also includes enabling both the privileged and the non-privileged modes if it is determined that the device is to operate in both the privileged and the non-privileged modes.

Abstract: A system, method and computer program for establishing communication between a peripheral device and programs resident on a wireless computer device. The device has a computer platform with a wireless communication portal and one or more resident programs, and the computer platform includes an operating system that manages wireless device resources and the interaction of the wireless device with other computer devices. When a peripheral device selectively communicates with the computer platform of the wireless device via a wired or wireless communication, the operating system of the wireless device identifies at least the type of peripheral device and links the peripheral device with one or more of the resident computer programs.

Abstract: An apparatus for treating a heart includes a housing member having a plurality of elongate channels defined therein and is movable between a first collapsed position and a second expanded position. A tissue attachment member is positioned in each channel. In one aspect, the apparatus is adapted for performing an anastomosis and includes a housing member having a plurality of elongate channels defined therein and which is movable between a fist collapsed position and a second expanded position. A surgical clip is positioned in each channel. A clip deployment mechanism projects the clips from their respective housings and a registration member approximates and aligns the first and second tubular structures. In a further aspect, helical barbs are movably affixed within sleeves formed on a sheetg of biocompatible material adapted for placement within a heart ventricle. Methods for treating a heart and reducing the volume of a heart ventricle are also provided.

Abstract: A plurality of pipe diffuser sections are arranged in a three to seven sided polygon, which allows a fluid to flow through distribution piping and the pipe sections and diffuse, through openings in the walls of the pipe diffuser sections, into a body of fluid contained in a tank.