Abstract: Provided herein are reagents, compositions, and therapies with which to treat Clostridium difficile infection and related disease conditions and pathologies, such as Clostridium difficile-associated diarrhea, resulting from infection by Clostridium difficile bacteria and the enterotoxins produced by these bacteria. In particular, antibodies or antigen-binding fragments thereof that bind specifically to toxin A and/or toxin B of C difficile and neutralize the activities of these toxins; compositions comprising such antibodies; and methods of using the antibodies and the compositions are provided.

Abstract: A dental illumination apparatus includes a lamp system mounted on a support structure. The lamp system includes a light source. A control system is provided for controlling the activation of the lamp system. A light guide shields soft tissues local to teeth of a subject from effects of ultraviolet radiation. The light guide includes a lamp attachment formation coupled to the lamp system, and a recording device in communication with the control system, the recording device including memory which stores the amount of time that the light source has been on since the beginning of a treatment procedure. A lip retractor, coupled to the light guide, is adapted to receive the lips of a patient.

Abstract: A method of delivering webpages to a browser includes delivering a first webpage using a streaming protocol that optimizes delivery of content of the first webpage where the first webpage includes information that may persist in a browser cache; delivering a second webpage without using the streaming protocol where the second webpage and the first webpage both reference a first resource; and forcing revalidation of the first resource stored on the browser cache.

Abstract: A method of delivering content of a webpage to a web browser on a device communicating with a network through a proxy server includes embedding a first nested browsing context in a parent browsing context of the web browser where the parent browsing context is associated with a first domain and the first nested browsing context is associated with a second domain; sending a request for content from the first nested browsing context to the second domain through the proxy server; and receiving at the first nested browsing context the content from the second domain.

Abstract: Provided herein are reagents, compositions, and therapies with which to treat Clostridium difficile infection and related disease conditions and pathologies, such as Clostridium difficile-associated diarrhea, resulting from infection by Clostridium difficile bacteria and the enterotoxins produced by these bacteria. In particular, antibodies or antigen-binding fragments thereof that bind specifically to toxin A and/or toxin B of C difficile and neutralize the activities of these toxins; compositions comprising such antibodies; and methods of using the antibodies and the compositions are provided.

Abstract: A method of delivering a webpage including dynamic content is disclosed. A request for the webpage directed to a third-party site is received. Likely components corresponding to the webpage is determined with a processor based at least in part on previous responses to similar requests. The determined likely components corresponding to the webpage are sent to a sender of the request. The webpage from the third-party site is received. The remaining components corresponding to the webpage are determined with the processor. The determined remaining components corresponding to the webpage are sent in response to the request.

Abstract: A dental illumination apparatus includes a lamp system mounted on a support structure. The lamp system includes a light source. A control system is provided for controlling the activation of the lamp system. A light guide shields soft tissues local to teeth of a subject from effects of ultraviolet radiation. The light guide includes a lamp attachment formation coupled to the lamp system, and a recording device in communication with the control system, the recording device including memory which stores the amount of time that the light source has been on since the beginning of a treatment procedure. A lip retractor, coupled to the light guide, is adapted to receive the lips of a patient.

Abstract: A reactor assembly includes a first block having an array of reactors defined therein and a second block having an array of openings defined within a surface of the second block. Each opening of he array of openings is substantially aligned with a corresponding opening of the array of reactors so that that each reactor is associated with at least one corresponding opening defined within the surface of the second block when the surface of the second block is placed on a surface of the first block. The first block is removably sealed against each surface defining the array of openings. A network of channels is defined within the second block. The network of channels is in fluid communication with a fluid source.

Abstract: A dental illumination system includes an adjustable self-supporting frame and a lamp head coupled to the frame. The lamp head includes a housing and a spacer having formations that is adapted to removably mechanically couple the lamp head to a reference device, again having formations, for facilitating illumination of a tooth by a light source contained within the lamp head. The spacer and lamp head may be formed integrally. If formed separately, both the lamp head and the spacer may include formations.

Abstract: Provided herein are reagents, compositions, and therapies with which to treat Clostridium difficile infection and related disease conditions and pathologies, such as Clostridium difficile-associated diarrhea, resulting from infection by Clostridium difficile bacteria and the enterotoxins produced by these bacteria. In particular, antibodies or antigen-binding fragments thereof that bind specifically to toxin A and/or toxin B of C difficile and neutralize the activities of these toxins; compositions comprising such antibodies; and methods of using the antibodies and the compositions are provided.

Abstract: The invention provides a system and method for integrating rental vehicle return with airline boarding pass generation. The system includes a rental identification tag located on a rental vehicle and a tag reader located at a rental vehicle return facility for reading and identifying the rental vehicle identification tag when the rental vehicle enters a range of the tag reader. The system additionally includes a database containing information linking a traveler to the rental identification tag and to airline reservation information of the traveler and a computing system communicating with the database and the tag reader to locate the airline reservation information of the traveler based on the identification provided by the tag reader. The system also includes a boarding pass generator for generating a boarding pass based on the airline reservation information upon receiving an instruction from the computing system.

Abstract: The present invention relates to a discrete optical correlation system. One embodiment of the present invention includes a portable electrical illumination system and an optically opaque hollow module, configured to releasably couple to the portable electrical illumination system in a manner such that when the portable electrical illumination system is activated, the system produces a discrete correlated or focused illumination output. The portable electrical illumination system further includes a light emitting diode, a power source, a switch, and a coupling mechanism. The optically opaque hollow module further includes at least two openings, a hollow internal region, an optically opaque outer surface, and a coupling mechanism disposed on at least one of the at least two openings. A fourth embodiment relates creating an adjustable aperture between two optically opaque sleeves sliding over an optically transparent module coupled to the portable electrical illumination system.

Abstract: The invention provides a system and method for integrating rental vehicle return with airline boarding pass generation. The system includes a rental identification tag located on a rental vehicle and a tag reader located at a rental vehicle return facility for reading and identifying the rental vehicle identification tag when the rental vehicle enters a range of the tag reader. The system additionally includes a database containing information linking a traveler to the rental identification tag and to airline reservation information of the traveler and a computing system communicating with the database and the tag reader to locate the airline reservation information of the traveler based on the identification provided by the tag reader. The system also includes a boarding pass generator for generating a boarding pass based on the airline reservation information upon receiving an instruction from the computing system.

Abstract: Via atomic cascade emission, an entangled pair of photons may be generated. A first one of the entangled pair may be ideal for long-distance communication. The other one may be suited for mapping to a long-lived atomic memory. Also, a deterministic single photon may be produced using a feedback system. If the feedback system indicates that an excitation exists in an atomic ensemble, then the atomic ensemble may be hit with a laser to produce the deterministic single photon. Furthermore, gas in the atomic ensemble may be subdivided into independent elements each of which may function as a memory element itself. In addition, dual species matter qubits may be entangled with light. A volume in an atomic ensemble may comprise a first isotope vapor storing a first state of a qubit. The volume may also comprise a second isotope vapor configured to store a second state of the qubit.

Abstract: A dental lamp boom hinge includes a pivot supporting a dental lamp head and a base supporting the pivot where the pivot may be rotated about a substantially vertical axis with respect to the base. The rotational movement between the pivot and the base is damped with a damping device. The damping device in one embodiment is adjustable to provide a variable level of damping.

Abstract: A dental illumination system includes an adjustable self-supporting frame and a lamp head coupled to the frame. The lamp head includes a housing and a spacer having formations that is adapted to removably mechanically couple the lamp head to a reference device, again having formations, for facilitating illumination of a tooth by a light source contained within the lamp head. The spacer and lamp head may be formed integrally. If formed separately, both the lamp head and the spacer may include formations.

Abstract: High throughput methods for screening genetic variants that are phenotypically distinguishable are provided. Methods for identifying “long-lived” genetic variants among a set of variants are also provided. Methods for identifying pharmaceutical compounds that can promote longevity in various subjects, including mammals, and that can delay the onset of various diseases associated with aging are also provided. Various vectors and host cells containing identified genes/gene products are useful for screening longevity-promoting compounds that can interact with life-span-regulating genes/gene products. Pharmaceutical compositions that can promote longevity are also provided.

Abstract: In one aspect, the present invention provides methods for determining whether a chemical agent modulates the biological activity of a GPR105 protein. The methods of this aspect of the invention include the steps of: (a) contacting a living cell, in vitro, with a chemical agent, wherein the living cell expresses a GPR105 protein having a biological activity; (b) determining whether the chemical agent modulates the biological activity of the GPR105 protein in the living cell; and (c) validating, in vivo, the modulating effect of the chemical agent on the biological activity of the GPR105 protein.

Abstract: A product design method includes accessing a defined product design structure. The product design structure includes a number of customer concerns, a number of physical properties associated with components of the product, and a number of relation models. Each customer concern is associated with at least one physical property via at least one mathematical relationship defined in at least one of the relation models. The method also includes receiving a value associated with one or more of the physical properties and calculating (using one or more of the relation models) the effect of the received value associated with the one or more physical properties on one or more of the customer concerns. Furthermore, the method includes displaying the calculated effect on the one or more customer concerns and receiving one or more adjustments of the value associated with one or more of the physical properties to create a desired effect on one or more of the customer concerns.

Abstract: A dental illumination system includes an adjustable self-supporting frame and a lamp head coupled to the frame. The lamp head includes a housing and a spacer having formations that is adapted to removably mechanically couple the lamp head to a reference device, again having formations, for facilitating illumination of a tooth by a light source contained within the lamp head. The spacer and lamp head may be formed integrally. If formed separately, both the lamp head and the spacer may include formations.