Patents by Inventor Brian Zambrowicz

Brian Zambrowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human proteases and polynucleotides encoding the same
    Patent number: 6777221
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: August 17, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, Erin Hilbun, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Novel human ion channel protein and polynucleotides encoding the same
    Publication number: 20040157259
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: March 18, 2004
    Publication date: August 12, 2004
    Inventors: Yi Hu, James Alvin Kieke, C. Alexander Turner, Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human ion channel protein and polynucleotides encoding the same
    Patent number: 6767736
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: July 27, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, James Alvin Kieke, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Novel human thrombospondin repeat proteins and polynucleotides encoding the same
    Publication number: 20040143113
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: January 20, 2004
    Publication date: July 22, 2004
    Inventors: Gregory Donoho, John Scoville, C. Alexander Turner, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Novel human proteases and polynucleotides encoding the same
    Publication number: 20040137502
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: January 28, 2004
    Publication date: July 15, 2004
    Inventors: Gregory Donoho, John Scoville, C. Alexander Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur T. Sands
  • Human kinase protein and polynucleotides encoding the same
    Patent number: 6746861
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: June 8, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, Erin Hilbun, C. Alexander Turner, Jr., Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human proteins and polynucleotides encoding the same
    Patent number: 6743907
    Abstract: Novel human CUB domain containing protein polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: June 1, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human proteases and polynucleotides encoding the same
    Patent number: 6743621
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: August 7, 2002
    Date of Patent: June 1, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, John Scoville, C. Alexander Turner, Jr., Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur T. Sands
  • Novel human membrane proteins
    Publication number: 20040077078
    Abstract: The nucleotide and amino acid sequences of several novel human G protein coupled receptors are described.
    Type: Application
    Filed: May 22, 2003
    Publication date: April 22, 2004
    Inventors: Frank Wattler, Gregory Donoho, C. Alexander Turner, Erin Hilbun, Michael Nehls, Brian Zambrowicz, Arthur T. Sands
  • Indexed library of cells containing genomic modifications and methods of making and utilizing the same
    Publication number: 20040072243
    Abstract: Methods and vectors (both DNA and retroviral) are provided for the construction of a Library of mutated cells. The Library will preferably contain mutations in essentially all genes present in the genome of the cells. The nature of the Library and the vectors allow for methods of screening for mutations in specific genes, and for gathering nucleotide sequence data from each mutated gene to provide a database of tagged gene sequences. Such a database provides a means to access the individual mutant cell clones contained in the Library. The invention includes the described Library, methods of making the same, and vectors used to construct the Library. Methods are also provided for accessing individual parts of the Library either by sequence or by pooling and screening. The invention also provides for the generation of non-human transgenic animals which are mutant for specific genes as isolated and generated from the cells of the Library.
    Type: Application
    Filed: February 4, 2003
    Publication date: April 15, 2004
    Applicant: Lexicon Genetics Incorporated
    Inventors: Arthur Sands, Glenn Friedrich, Brian Zambrowicz, Allan Bradley
  • Human thrombospondin repeat proteins and polynucleotides encoding the same
    Patent number: 6720412
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: February 15, 2001
    Date of Patent: April 13, 2004
    Assignee: Lexicon Genetics Corporation
    Inventors: Gregory Donoho, John Scoville, C. Alexander Turner, Jr., Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human kinase protein and polynucleotides encoding the same
    Patent number: 6720173
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: April 13, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Brian Mathur, C. Alexander Turner, Jr., Alejandro Abuin, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human kinase proteins and polynucleotides encoding the same
    Patent number: 6716616
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: April 6, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human calcium dependent proteases, polynucleotides encoding the same, and uses thereof
    Patent number: 6716614
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: July 23, 2002
    Date of Patent: April 6, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human transferase proteins and polynucleotides encoding the same
    Patent number: 6692947
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: February 17, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, C. Alexander Turner, Jr., Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur T. Sands
  • Novel human kinase proteins and polynucleotides encoding the same
    Publication number: 20040014112
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in theraapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: May 27, 2003
    Publication date: January 22, 2004
    Inventors: Gregory Donoho, John Scoville, C. Alexander Turner, Glenn Friedrich, Brian Zambrowicz, Alejandro Abuin, Arthur T. Sands
  • Novel human GABA receptor proteins and polynucleotides encoding the same
    Publication number: 20030229217
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: May 12, 2003
    Publication date: December 11, 2003
    Inventors: C. Alexander Turner, Brian Mathur, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Novel human proteases and polynucleotides encoding the same
    Publication number: 20030225258
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: April 17, 2003
    Publication date: December 4, 2003
    Inventors: Gregory Donoho, C. Alexander Turner, Glenn Friedrich, John Scoville, Brian Zambrowicz, Arthur T. Sands
  • Novel human 7TM proteins and polynucleotides encoding the same
    Publication number: 20030225246
    Abstract: The nucleotide and amino acid sequences of two novel human G protein coupled receptors are described.
    Type: Application
    Filed: March 17, 2003
    Publication date: December 4, 2003
    Inventors: Yi Hu, Michael B. Burnett, Brian Zambrowicz
  • Novel human transporter proteins and polynucleotides encoding the same
    Publication number: 20030220491
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: January 15, 2003
    Publication date: November 27, 2003
    Inventors: D. Wade Walke, Nathaniel L. Wilganowski, Yi Hu, James Alvin Kieke, Brian Zambrowicz, Jean-Pierre Revelli, C. Alexander Turner