Patents by Inventor Brian Zambrowicz

Brian Zambrowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel human enzymes and polynucleotides encoding the same
    Publication number: 20060063245
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: September 15, 2005
    Publication date: March 23, 2006
    Inventors: D. Walke, Nathaniel Wilganowski, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Novel mutated mammalian cells and animals
    Publication number: 20060031947
    Abstract: Novel mutated mammalian cells are provided that have been characterized by identifying the sequence of the genes that have been mutated. Preferably, novel mutated cells are murine ES cells that stably incorporate retroviral gene trap constructs in the specifically identified genes. The novel mutated cells and animals are useful in functional genomic analysis, and in the discovery and development of new therapeutic and diagnostics agents and methods.
    Type: Application
    Filed: December 23, 2004
    Publication date: February 9, 2006
    Inventors: Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Novel human GABA receptor proteins and polynucleotides encoding the same
    Publication number: 20060025581
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: July 25, 2005
    Publication date: February 2, 2006
    Inventors: C. Turner, Brian Mathur, Glenn Friedrich, Brian Zambrowicz, Arthur Sands
  • Human uncoupling proteins and polynucleotides encoding the same
    Patent number: 6987178
    Abstract: The present invention relates to methods and compositions for the treatment of biological disorders regulatable by the controlled expression or inhibition of the described uncoupling proteins (UCPs).
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: January 17, 2006
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur, Brian Zambrowicz, Arthur T. Sands
  • Novel human transferase proteins and polynucleotides encoding the same
    Publication number: 20050287568
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: May 20, 2005
    Publication date: December 29, 2005
    Inventors: Gregory Donobo, Erin Hilbun, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands, D. Walke, Nathaniel Wilganowski, Yi Hu, James Kieke, David Potter
  • Novel human membrane protein and polynucleotides encoding the same
    Publication number: 20050261488
    Abstract: The nucleotide and amino acid sequences of a novel human G protein-coupled receptor (NGPCR) is disclosed. The NGPCR is somewhat similar to human latrophilin, lectomedin, and serpentine, proteins, among others.
    Type: Application
    Filed: March 31, 2005
    Publication date: November 24, 2005
    Inventors: D. Walke, Nathaniel Wilganowski, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Noved human proteases and polynucleotides encoding the same
    Publication number: 20050222401
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: January 10, 2005
    Publication date: October 6, 2005
    Inventors: Gregory Donoho, John Scoville, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Novel human proteases and polynucleotides encoding the same
    Publication number: 20050214783
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: July 12, 2004
    Publication date: September 29, 2005
    Inventors: D. Walke, C. Turner, Alejandro Abuin, Glenn Friedrich, Brian Zambrowicz, Arthur Sands
  • Novel human 7TM proteins and polynucleotides encoding the same
    Publication number: 20050215776
    Abstract: The nucleotide and amino acid sequences of two novel human G protein coupled receptors are described.
    Type: Application
    Filed: November 16, 2004
    Publication date: September 29, 2005
    Inventors: Yi Hu, Michael Burnett, Brian Zambrowicz
  • Novel human phosphatases and polynucleotides encoding the same
    Publication number: 20050208571
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: May 12, 2005
    Publication date: September 22, 2005
    Inventors: D. Walke, John Scoville, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • NOVEL HUMAN CARBOXYPEPTIDASES AND POLYNUCLEOTIDES ENCODING THE SAME
    Publication number: 20050191641
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: June 21, 2004
    Publication date: September 1, 2005
    Inventors: Gregory Donoho, C. Turner, Michael Nebls, Glenn Friedrich, Brian Zambrowicz, Arthur Sands
  • Novel mutated mammalian cells and animals
    Publication number: 20050186677
    Abstract: Novel mutated mammalian cells are provided that have been characterized by identifying the sequence of the genes that have been mutated. Preferably, novel mutated cells are murine ES cells that stably incorporate retroviral gene trap constructs in the specifically identified genes. The novel mutated cells and animals are useful in functional genomic analysis, and in the discovery and development of new therapeutic and diagnostics agents and methods.
    Type: Application
    Filed: October 13, 2004
    Publication date: August 25, 2005
    Inventors: Glenn Friedrich, Brian Zambrowicz, Arthur Sands
  • Novel human transporter proteins and polynucleotides encoding the same
    Publication number: 20050181397
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: December 30, 2004
    Publication date: August 18, 2005
    Inventors: Gregory Donoho, John Scoville, Brian Zambrowicz, Emily Cullinan, James Kieke, Yi Hu, C. Turner, D. Walke
  • Novel human ATPase proteins and polynucleotides encoding the same
    Publication number: 20050182248
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: January 3, 2005
    Publication date: August 18, 2005
    Inventors: Gregory Donoho, C. Turner, Erin Hilbun, Michael Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur Sands
  • NOVEL HUMAN UNCOUPLING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME
    Publication number: 20050181500
    Abstract: The present invention relates to methods and compositions for the treatment of biological disorders regulatable by the controlled expression or inhibition of the described NUCPs.
    Type: Application
    Filed: June 7, 2002
    Publication date: August 18, 2005
    Inventors: C. Turney, Brian Mathur, Brian Zambrowicz, Arthur Sands
  • Human transferase proteins and polynucleotides encoding the same
    Patent number: 6929937
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: August 16, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur T. Sands, D. Wade Walke, Nathaniel L. Wilganowski
  • Novel human notch ligand proteins and polynucleotides encoding the same
    Publication number: 20050170389
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: December 27, 2004
    Publication date: August 4, 2005
    Inventors: C. Turner, Michael Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur Sands
  • Novel human kinase protein and polynucleotides encoding the same
    Publication number: 20050170364
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: April 21, 2004
    Publication date: August 4, 2005
    Inventors: Gregory Donoho, Erin Hilbun, C. Turner, Glenn Friedrich, Brian Zambrowicz, Arthur Sands
  • Novel human proteins and polynucleotides encoding the same
    Publication number: 20050170384
    Abstract: Novel human amino acid sequences are reported and nucleotide sequences encoding the same.
    Type: Application
    Filed: November 29, 2004
    Publication date: August 4, 2005
    Inventors: C. Turner, Gregory Donoho, Michael Nehls, Erin Hilbun, Brian Zambrowicz, Arthur Sands
  • Novel human proteases and polynucleotides encoding the same
    Publication number: 20050170395
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: December 30, 2004
    Publication date: August 4, 2005
    Inventors: Gregory Donoho, C. Turner, Glenn Friedrich, John Scoville, Brian Zambrowicz, Arthur Sands