Abstract: A control rod assembly having a connecting rod, a spider, a plurality of control rods, a coupling sleeve secured to the connecting rod and including a body portion defining at least one cam pin, and a barrel cam defining a cam track, the barrel cam being rotatably secured to the spider. The cam track includes a first camming surface and a second camming surface that are configured so that the barrel cam rotates in a first direction as the at least one cam pin slides along the first and second camming surfaces. The barrel cam rod is rotatable between a first position in which the spider is connected to the connecting rod and a second position in which the spider is disconnected from the connecting rod.

Abstract: A control rod drive mechanism having a torque tube, a control rod assembly including a connecting rod disposed within the torque tube and including an annular collar defining a key slot, an elongated key that is slidably receivable within the key slot, a lock cam assembly rotatably secured to a top end of the connecting rod and including a locking cam, and a holdout collar disposed non-rotatably within the torque tube, the holdout collar including a locking recess with an entry slot, wherein in a first axial position the lock cam assembly is rotatable with respect to the torque tube, and a second axial position the lock cam assembly is non-rotatable with respect to the torque tube.

Abstract: Described are recombinant nucleic acid molecules for increased expression of Cas9 in human liver. In some embodiments, the recombinant nucleic acid molecules are provided in compositions and methods for gene editing, specifically using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR).

Abstract: A support system and method to support structures in a substrate such as the ground. The system generally comprises a tubular hollow body with a conical head, and a number of smaller hollow tubes positioned inside. Each of the smaller tubes having a bend and an opening adapted to communicate with a corresponding opening in the hollow body head. In use, the assembly is driven into the substrate to the desired depth, and rods are driven down each of the smaller tubes so that they at least partially extend out from the head and into the surrounding substrate. The support system may also include a screw structure at the head to aid in driving the support system into the ground, and guards to protect the smaller tubes from damage during installation.

Abstract: A process for synthesizing and separating secretory IgA from a mixture of IgA monmer and IgA dimer is provided. The process includes covalently binding affinity tagged or epitope tagged recombinant secretory component to the IgA dimer in the mixture and binding the affinity tagged or an epitope tagged secretory IgA to immobilized moieties on the solid phase support resin to which the affinity tag or epitope tag binds and then eluting the affinity tagged or an epitope tagged secretory IgA with release buffer. A process for synthesizing and separating secretory IgM from a mixture of IgM and other plasma proteins is also provided. The process includes covalently binding affinity tagged or an epitope tagged recombinant secretory component to the IgM in the mixture and binding the affinity tagged or an epitope tagged secretory IgM to immobilized moieties on the solid phase support resin and then eluting the peptide tagged secretory IgM with a release buffer.

Abstract: Aspects of this disclosure concern controllers and control methods for applying a drive voltage to bus bars of optically switchable devices such as electrochromic devices. Such devices are often provided on windows such as architectural glass. In certain embodiments, the applied drive voltage is controlled in a manner that efficiently drives an optical transition over the entire surface of the electrochromic device. The drive voltage is controlled to account for differences in effective voltage experienced in regions between the bus bars and regions proximate the bus bars. Regions near the bus bars experience the highest effective voltage. In some cases, feedback may be used to monitor an optical transition. In these or other cases, a group of optically switchable devices may transition together over a particular duration to achieve approximately uniform tint states over time during the transition.

Abstract: A stabilized toilet seat and toilet bowl that operates to prevent the toilet seat, when placed in a parallel orientation relative to the rim of a toilet bowl, from moving laterally or diagonally. The stabilized toilet seat and toilet bowl includes an interlocking system integral with both the toilet seat and the toilet bowl which automatically engages whenever the toilet seat is hinged into the parallel orientation without placing any restriction on the toilet seat's hinging movement into or out of the parallel orientation. A locking protrusion integral with the toilet seat and a locking slot integral with the toilet bowl may form the interlocking system.

Abstract: Aspects of this disclosure concern controllers and control methods for applying a drive voltage to bus bars of optically switchable devices such as electrochromic devices. Such devices are often provided on windows such as architectural glass. In certain embodiments, the applied drive voltage is controlled in a manner that efficiently drives an optical transition over the entire surface of the electrochromic device. The drive voltage is controlled to account for differences in effective voltage experienced in regions between the bus bars and regions proximate the bus bars. Regions near the bus bars experience the highest effective voltage.

Abstract: Disclosed are methods of promoting wound healing in a patient in need thereof comprising administering to the patient a composition comprising a neonatal fibrin scaffold. Further disclosed are in vitro methods for evaluating a target composition on human wound healing comprising a neonatal porcine plasma scaffold with the target composition and evaluating scaffold properties of the plasma sample.

Abstract: A system and method for reducing a vapor temperature in a packed distillation column. Liquid is collected from a packed section of the packed distillation column in a liquid collector disposed below the packed section. A super-heated vapor is distributed from a vapor feed disposed below the packed section such that the super-heated vapor contacts the liquid of the liquid collector and reduces a temperature of the super-heated vapor.

Abstract: A system and method of delivering a package to a residence having an address and a locker with a lock is disclosed. The method comprises the steps of, remotely selecting an item from a menu of items provided by a vendor and requesting the item be delivered to the residence, providing the vendor delivery information including the address and the combination code to the lock, shipping the package to the residence, reviewing the combination code associated with the package, opening the locker by manipulating the proper combination on the lock, placing the package in the locker; and closing door of the locker. The locker has an outer frame and door that cooperate to allow any liquid to drain out from the front of the locker and outside the residence and a combination lock that allows for the combination to be easily changed by the resident.

Abstract: An appliance includes a system on chip (SOC) and converter. The appliance accepts A/V data (e.g., HDMI®, SDI®, IP) from external sources, encodes A/V data using an encoder of the SOC and performs additional services via other computational components of the SOC. The SOC may be a mobile SOC. The appliance may operate as an edge appliance, edge encoder, or edge-based origin-server, for instance at an edge endpoint of a mesh network, allowing many-to-many distribution of A/V data, performing computationally efficient A/V encoding, while also making available additional computational resources (e.g., cycles of CPUs, GPUs, DSPs, AI/ML NPUs) to provide other services at the edge in addition to efficient A/V encoding.

Abstract: A method and system for managing payment transactions for a merchant using a computing device coupled to a memory device is described. Each transaction is initiated by a consumer using a payment card. The method includes receiving a registration request from a candidate merchant for enrollment within a manager module wherein the registration request includes registration data associated with the candidate merchant, executing a primary approval process using at least some of the registration data, and transmitting an account request message requesting an opening of a merchant account for the candidate merchant with an acquiring bank upon approval. The method further includes receiving, in real-time, merchant account data associated with the candidate merchant from the acquiring bank upon approval by a secondary approval process wherein the candidate merchant becomes a registered merchant upon the secondary approval.

Abstract: This disclosure provides systems, methods, and apparatus for controlling transitions in an optically switchable device. In one aspect, a controller for a tintable window may include a processor, an input for receiving output signals from sensors, and instructions for causing the processor to determine a level of tint of the tintable window, and an output for controlling the level of tint in the tintable window. The instructions may include a relationship between the received output signals and the level of tint, with the relationship employing output signals from an exterior photosensor, an interior photosensor, an occupancy sensor, an exterior temperature sensor, and a transmissivity sensor. In some instances, the controller may receive output signals over a network and/or be interfaced with a network, and in some instances, the controller may be a standalone controller that is not interfaced with a network.

Abstract: Disclosed are compositions comprising a nucleic acid sequence conjugated to one or more MGS peptides. Disclosed are methods of modifying gene expression of a gene of interest comprising administering to a cell a composition comprising a nucleic acid sequence conjugated to one or more MGS peptides, wherein the nucleic acid sequence binds to the RNA transcribed from the gene of interest, the gene of interest or a sequence upstream of the gene of interest. Disclosed are methods of targeting a gene of interest in an intracellular target comprising administering to a cell a composition comprising a nucleic acid sequence conjugated to one or more MGS peptides, wherein the MGS peptide targets the intracellular target, wherein the nucleic acid sequence binds to the RNA transcribed from the gene interest in an intracellular target.

Abstract: A system for sensing and responding to detected activity or an event in a region is provided. The system may comprise: a modular edge computing platform configured to provide a predetermined functionality for a particular application, the modular edge computing platform is configured to process sensor data to generate processed data, and transmit the processed data; and a remote entity that comprises (i) a cloud analytic configured to receive the processed data from the modular edge computing platform and analyze the processed data, and (ii) a cloud user interface module configured to provide a graphical user interface on a user device, the graphical user interface displays one or more results generated by the cloud analytic upon analyzing the processed data.

Abstract: Provided herein are compositions and methods for promoting hematopoietic cell cytotoxicity.

Abstract: A vehicle wheel alignment system has a plurality of cameras, each camera for viewing a respective target disposed at a respective wheel of the vehicle and capturing image data of the target as the wheel and target are continuously rotated a number of degrees of rotation without a pause. The image data is used to calculate a minimum number of poses of the target of at least one pose for every five degrees of rotation as the wheel and target are continuously rotated the number of degrees of rotation without a pause. At least one of the cameras comprises a data processor for performing the steps of preprocessing the image data, and calculating an alignment parameter for the vehicle based on the preprocessed image data.

Abstract: Onboard EC window controllers are described. The controllers are configured in close proximity to the EC window, for example, within the IGU. The controller may be part of a window assembly, which includes an IGU having one or more EC panes, and thus does not have to be matched with the EC window, and installed, in the field. The window controllers described herein have a number of advantages because they are matched to the IGU containing one or more EC devices and their proximity to the EC panes of the window overcomes a number of problems associated with conventional controller configurations. Also described are self-meshing networks for electrochromic windows.

Abstract: Described herein are compositions and methods of using placental stem cell recruiting factors, more specifically, isolated placental stem cell recruiting factors. In one embodiment, isolated placental stem cell recruiting factors are delivered to a site such as a diseased or injured organ and/or body part in an amount sufficient to recruit stem cells to the site.