Patents by Inventor C. Carlson

C. Carlson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline Form Of Nicotinamide Riboside
    Publication number: 20170210774
    Abstract: Provided are crystalline forms of nicotinamide riboside, including a Form I of nicotinamide riboside chloride according to formula (I). Also disclosed are pharmaceutical compositions comprising the crystalline Form I of nicotinamide riboside chloride, and methods of producing such pharmaceutical compositions. In other aspects, the present disclosure pertains to methods comprising administering to a subject the crystalline Form I of nicotinamide riboside chloride. The present disclosure also provides methods of preparing the crystalline Form I of nicotinamide riboside chloride. Also provided are a crystalline Form I of nicotinamide riboside chloride that is prepared according to any of the disclosed methods for preparing the crystalline Form I.
    Type: Application
    Filed: July 24, 2015
    Publication date: July 27, 2017
    Inventors: Erik C. Carlson, Michael C. Standen, Westin M. Morrill
  • COMPOSITIONS AND METHODS FOR VISUALIZATION OF THE VITREOUS
    Publication number: 20170202981
    Abstract: The invention provides compositions for rendering a vitreous cavity visible during a surgical procedure to alleviate a structural disorder caused by the vitreous in an eye, and methods of using the compositions. The compositions are vitreous delineating agents that comprise a hyaluronan binding peptide linked to an optically detectable moiety. Such compositions can be in a formulation that may be a solution, a suspension, or an emulsion, and would be injected into the vitreous shortly prior to use. The composition may additionally contain a therapeutic agent, a diagnostic agent, or a chemosensing material, in use, the composition marks or delineates the vitreous by binding preferentially to the hyaluronan that permeates the vitreous humor and binding little or not at all to surrounding tissues such as the retina.
    Type: Application
    Filed: June 24, 2015
    Publication date: July 20, 2017
    Applicant: Novartis AG
    Inventors: Joy GHOSH, Thaddeus Peter DRYJA, Michael ROGUSKA, Eric C. CARLSON
  • Efficient elimination of access to data on a writable storage media
    Patent number: 9588705
    Abstract: A computer program product for eliminating access to data within a writable storage media cartridge includes a computer readable medium having program instructions embodied therewith. The program instructions are executable by a processing circuit to cause the processing circuit to determine whether a first portion of data on the writable storage media cartridge is encrypted, and determine whether key shredding is enabled. In response to determining that key shredding is not enabled, the processing circuit causes performance of a long erase on at least the encrypted first portion of data, and causes shredding of an encryption key related to said encrypted first portion of data.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: March 7, 2017
    Assignee: International Business Machines Corporation
    Inventors: Wayne C. Carlson, Cheryl M. Friauf, Gregory T. Kishi, Duke A. Lee, Jonathan W. Peake
  • Polyconjugates for Delivery of RNAi triggers to Tumor Cells In Vivo
    Publication number: 20170022497
    Abstract: The present invention is directed compositions for delivery of RNA interference (RNAi) triggers to integrin positive tumor cells in vivo. The compositions comprise RGD ligand-targeted amphipathic membrane active polyamines reversibly modified with enzyme cleavable dipeptide-amidobenzyl-carbonate masking agents. Modification masks membrane activity of the polymer while reversibility provides physiological responsiveness. The reversibly modified polyamines (dynamic polyconjugate or conjugate) are further covalently linked to an RNAi trigger.
    Type: Application
    Filed: September 28, 2016
    Publication date: January 26, 2017
    Inventors: David B. Rozema, So Wong, Weijun Cheng, Aaron M. Almeida, Andrei V. Blokhin, Jeffrey C. Carlson
  • REDIRECTION IN A NEUTRAL-HOST NETWORK
    Publication number: 20170006513
    Abstract: A method for redirecting a user equipment (UE) from a first network to a second network is described. The method includes determining, at a wireless access point of the first network, information for the UE about one or more mobile network operator (MNO) networks. The method also includes selecting the second network for redirection from among the one or more MNO networks based on the determined information. The method further includes sending the UE a redirection message that redirects the UE from the first network to the second network.
    Type: Application
    Filed: July 2, 2015
    Publication date: January 5, 2017
    Inventors: Jangwon Lee, Nam Soo Park, Rajat Prakash, Neil C. Carlson
  • Biologically Cleavable Tetrapeptide Linking Agents
    Publication number: 20160347793
    Abstract: Tetrapeptide linkers for reversibly linking a first compound to a amine-containing second compound are described. Compounds containing the tetrapeptide linkers and methods of using the tetrapeptide linkers are also described.
    Type: Application
    Filed: May 27, 2016
    Publication date: December 1, 2016
    Inventors: Jeffrey C. Carlson, Andrei V. Blokhin
  • Compositions and Methods for Inhibiting Gene Expression of Hif2alpha
    Publication number: 20160348107
    Abstract: RNA interference (RNAi) triggers and RNAi trigger conjugates for inhibiting the expression of Hif2? (EPAS1) gene are described. Pharmaceutical compositions comprising one or more Hif2? RNAi triggers optionally with one or more additional therapeutics are also described. Delivery of the described Hif2? RNAi triggers to tumor cells in vivo provides for inhibition of Hif2? gene expression and treatment of cancer.
    Type: Application
    Filed: May 27, 2016
    Publication date: December 1, 2016
    Inventors: So Wong, David L. Lewis, David B. Rozema, Darren H. Wakefield, Steven B. Kanner, Weijun Cheng, Lauren J. Almeida, Andrei V. Blokhin, Jeffrey C. Carlson, Anthony L. Nicholas, Aaron Almeida, Jonathan D. Benson, Justin Woods
  • Polyconjugates for delivery of RNAi triggers to tumor cells in vivo
    Patent number: 9487556
    Abstract: The present invention is directed compositions for delivery of RNA interference (RNAi) triggers to integrin positive tumor cells in vivo. The compositions comprise RGD ligand-targeted amphipathic membrane active polyamines reversibly modified with enzyme cleavable dipeptide-amidobenzyl-carbonate masking agents. Modification masks membrane activity of the polymer while reversibility provides physiological responsiveness. The reversibly modified polyamines (dynamic polyconjugate or conjugate) are further covalently linked to an RNAi trigger.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: November 8, 2016
    Assignee: Arrowhead Pharmaceuticals, Inc.
    Inventors: Weijun Cheng, So Wong, Aaron M. Almeida, David B. Rozema, Andrei V. Blokhin, Jeffrey C. Carlson
  • Disubstituted maleic anhydrides with altered kinetics of ring closure
    Patent number: 9481661
    Abstract: We describe anhydride compounds suitable for physiologically labile modification of amine-containing molecules. The described anhydrides form reversible linkages having desirable kinetics for in vivo delivery of biologically active molecules. Also described are endosomolytic polymers formed by modification of membrane active polyamines with the described anhydrides.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: November 1, 2016
    Assignee: Arrowhead Madison, Inc.
    Inventors: Andrei V Blokhin, David B Rozema, Jonathan D Benson, Jeffrey C Carlson
  • Disubstituted Maleic Anhydrides with Altered Kinetics of Ring Closure
    Publication number: 20160272605
    Abstract: We describe anhydride compounds suitable for physiologically labile modification of amine-containing molecules. The described anhydrides form reversible linkages having desirable kinetics for in vivo delivery of biologically active molecules. Also described are endosomolytic polymers formed by modification of membrane active polyamines with the described anhydrides.
    Type: Application
    Filed: May 27, 2016
    Publication date: September 22, 2016
    Inventors: Andrei V. Blokhin, David B. Rozema, Jonathan D. Benson, Jeffrey C. Carlson
  • Nanoscale structures on optical fiber for surface enhanced Raman scattering and methods related thereto
    Patent number: 9395304
    Abstract: A nanoscale structure fabricated on a planar end facet of an optic fiber is described, to enable detection of molecules by surface-enhanced Raman scattering. The nanoscale structure may comprise an array of nanopillars. The nanoscale structure may also comprise a non periodic, or random, surface-relief structure. The nanoscale structure may be coated in a metal, comprising, for example, silver, gold, aluminum, iridium, platinum, palladium, copper, or a combination of the same. The nanoscale structure may be fabricated on a planar end facet of an optical fiber by interference lithography.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: July 19, 2016
    Assignees: Lawrence Livermore National Security, LLC, The Regents of The University of California
    Inventors: Xuan Yang, Tiziana C. Bond, Jerald Britten, Thomas C. Carlson, Nazar Ileri, Cindy Larson, Claire Gu
  • EFFICIENT ELIMINATION OF ACCESS TO DATA ON A WRITABLE STORAGE MEDIA
    Publication number: 20160196081
    Abstract: A computer program product for eliminating access to data within a writable storage media cartridge includes a computer readable medium having program instructions embodied therewith. The program instructions are executable by a processing circuit to cause the processing circuit to determine whether a first portion of data on the writable storage media cartridge is encrypted, and determine whether key shredding is enabled. In response to determining that key shredding is not enabled, the processing circuit causes performance of a long erase on at least the encrypted first portion of data, and causes shredding of an encryption key related to said encrypted first portion of data.
    Type: Application
    Filed: March 11, 2016
    Publication date: July 7, 2016
    Inventors: Wayne C. Carlson, Cheryl M. Friauf, Gregory T. Kishi, Duke A. Lee, Jonathan W. Peake
  • Solid-phase supports and uses thereof
    Patent number: 9376385
    Abstract: The present disclosure relates to solid-phase azide supports, methods for making solid-state azide supports, and methods for capturing alkynes using the same. The present disclosure also relates to kits for solid-phase azide supports.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: June 28, 2016
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Erin C. Carlson, Darci Trader, Ashley Sidebottom
  • TACTILE GUIDANCE ARRANGEMENT FOR VEHICLES
    Publication number: 20160174454
    Abstract: Embodiments include a tactile guidance system and various mechanisms for orienting and mounting the tactile guidance system on motorized vehicles such as agricultural spray vehicles. For example, a rod-shaped tactile guidance detector is positioned protruding out sideways from the inner side of each of the front wheels of a self-propelled sprayer vehicle or a tractor. The guidance system is used to detect the location of objects including crops and plants and determine a path of travel.
    Type: Application
    Filed: December 14, 2015
    Publication date: June 23, 2016
    Inventors: Austin H. Phan, Bin Shi, William A. Brett, Brandon C. Carlson, Tyler D. Schleicher
  • MEDIUM WITH A PLANT NON-METABOLIZABLE SUGAR FOR IMPROVING SEED GERMINATION
    Publication number: 20160081336
    Abstract: What is described is a nutritive media for a manufactured seed comprising a plant non-metabolizable sugar and a manufactured seed comprising plant non-metabolizable sugar in its nutritive medium
    Type: Application
    Filed: September 11, 2015
    Publication date: March 24, 2016
    Applicant: WEYERHAEUSER NR COMPANY
    Inventors: Jeffrey E. Hartle, Craig N. Cootsona, William C. Carlson, Katie A. Brinkerhoff, James A. Grob
  • SYSTEM FOR FACILITATING FLUID MOVEMENT IN CLOSED MOLDS
    Publication number: 20160046041
    Abstract: A vacuum bagging system may include a layer assembly defining a fluid flow channel. The layer assembly may include a contact layer mounted to a composite part positionable within an outer mold line (OML) tool. The contact layer may have a contact layer width defined by opposing contact layer side edges. The layer assembly may further include an inner layer mounted to the contact layer and having inner layer side edges located between the contact layer side edges. The fluid flow channel may extend along at least a portion of the composite part to at least one part end. The vacuum bagging system may include an internal vacuum bag positionable against the inner layer. An inner mold line (IML) tool may support the internal vacuum bag. The contact layer width may be less than an IML tool width.
    Type: Application
    Filed: October 29, 2015
    Publication date: February 18, 2016
    Inventors: Brett I. Lyons, Lisa C. Carlson, Stanley W. Stawski, Robert B. Miller, Matt Wallen, Jens Rossfeldt
  • SEGMENTED BOOM SYSTEM FOR WORK VEHICLE
    Publication number: 20160037764
    Abstract: Embodiments of a boom system for a work vehicle has a first boom member with a plurality of first boom segments aligned lengthwise to extend along a first boom dimension and a second boom member with a plurality of second boom segments aligned lengthwise to extend in the first boom dimension and spaced from the first boom member in a second boom dimension. The boom system also has a union spanning the second boom dimension to couple the first boom member to the second boom member and having a first coupling segment joining consecutive first boom sections together and a second coupling segment joining consecutive second boom sections together.
    Type: Application
    Filed: August 4, 2015
    Publication date: February 11, 2016
    Inventors: Andrew E. DePriest, Richard J. Chowaniec, Jr., Gregory E. Peterson, Gregory S. McCunn, Jonathan J. Nelson, Sankaran Subramaniam, Nathan Tortorella, Garry E. Baxter, Brandon C. Carlson, Kent A. Klemme, Dolly Y. Wu
  • FOLDING LIGHTWEIGHT SPRAYER BOOM SYSTEM
    Publication number: 20160038961
    Abstract: An example embodiment includes an agricultural sprayer having a boom that supports the fluid distribution pipes and spray nozzles. The boom is sectioned and folds in such a way to comply with transport dimension requirements or to facilitate storage. The spray nozzles are alternatively mounted underneath the boom or behind the boom in a way to avoid damage if the boom encounters obstacles; the mounting configurations do not hamper the boom folding for transport.
    Type: Application
    Filed: July 22, 2015
    Publication date: February 11, 2016
    Inventors: Brandon C. Carlson, Patrick J. Fisher, Kent A. Klemme, Ryan S. Ullmann, Garry E. Baxter, Jonathan D. Ackermann
  • NANOSCALE STRUCTURES ON OPTICAL FIBER FOR SURFACE ENHANCED RAMAN SCATTERING AND METHODS RELATED THERETO
    Publication number: 20150369744
    Abstract: A nanoscale structure fabricated on a planar end facet of an optic fiber is described, to enable detection of molecules by surface-enhanced Raman scattering. The nanoscale structure may comprise an array of nanopillars. The nanoscale structure may also comprise a non periodic, or random, surface-relief structure. The nanoscale structure may be coated in a metal, comprising, for example, silver, gold, aluminum, iridium, platinum, palladium, copper, or a combination of the same. The nanoscale structure may be fabricated on a planar end facet of an optical fiber by interference lithography.
    Type: Application
    Filed: May 23, 2013
    Publication date: December 24, 2015
    Inventors: Xuan YANG, Tiziana C. BOND, Jerald BRITTEN, Thomas C. CARLSON, Nazar ILERI, Cindy LARSON, Claire GU
  • System and method for facilitating fluid movement in close-molded composite parts
    Patent number: 9199419
    Abstract: A vacuum bagging system may include a layer assembly defining a fluid flow channel. The layer assembly may include a contact layer mounted to a composite part positionable within an outer mold line (OML) tool. The contact layer may have a contact layer width defined by opposing contact layer side edges. The layer assembly may further include an inner layer mounted to the contact layer and having inner layer side edges located between the contact layer side edges. The fluid flow channel may extend along at least a portion of the composite part to at least one part end. The vacuum bagging system may include an internal vacuum bag positionable against the inner layer. An inner mold line (IML) tool may support the internal vacuum bag. The contact layer width may be less than an IML tool width.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: December 1, 2015
    Assignee: The Boeing Company
    Inventors: Brett I. Lyons, Lisa C. Carlson, Stanley W. Stawski, Robert B. Miller, Matt Wallen, Jens Rossfeldt