Abstract: A manufactured seed is provided. The manufactured seed includes a seed shell housing a nutritive media and a restraint disposed within the seed shell. The restraint includes a cavity. The manufactured seed also includes an embryo disposed within the cavity and a fill material disposed within the cavity. The manufactured further includes a seal disposed on the seed shell to seal the embryo within the seed shell.

Abstract: A plastic window frame trim is for installation of a window in a corrugated metal building wall having a cut opening with a top edge, bottom edge, and side edges, each of the edges being backed by framing members. The window frame trim includes: a frame header J-channel with a flange; a frame footer J-channel with a flange; a pair of nailing fins; and fasteners. The trim header J-channel, footer J-channel, and nailing fins are attached to the window frame. The window frame is lifted so frame header J-channel flange slides between the top edge of the metal building wall and a framing member at the top of the cut opening. The window is lowered so footer J-channel flange slides between the bottom edge of the metal building wall and a framing member at the bottom of the cut opening so that window frame rest on the window sill. Fasteners attach the window frame to the framing members through the metal building wall. Trim caps snap over the nailing fins to finish the trimmed window.

Abstract: A plastic window frame trim is for installation of a window in a corrugated metal building wall having a cut opening with a top edge, bottom edge, and side edges, each of the edges being backed by framing members, the window having an accessory groove. The window frame trim includes: a frame header J-channel with a flange; a frame footer J-channel with a flange; a pair of nailing fins; and fasteners. The trim header J-channel, footer J-channel, and nailing fins are attached to the window at the accessory groove on the window frame. The window frame is lifted so frame header J-channel flange slides between the top edge of the metal building wall and a framing member at the top of the cut opening. The window is lowered so footer J-channel flange slides between the bottom edge of the metal building wall and a framing member at the bottom of the cut opening so that window frame rest on the window sill. Fasteners attach the window frame to the framing members through the metal building wall.

Abstract: A rail line sensing and safety system adapted to reliably sense the presence, and optionally the direction and speed, of vehicles traveling on a rail line, and when a vehicle is sensed, to indicate whether a safety device, such as crossing gates, lights, bells, etc., should be activated. The system comprises at least one detection module typically mounted on a rail, at least one remote module typically located near a detection module, and at least one control module typically located near a safety device. In operation, a detection module senses a vehicle traveling on a rail line and sends signals to a remote module. The remote module then processes signals received from the detection module and transmits signals to the control module. The control module then directs, either directly or indirectly as a backup or supplement to an existing sensing and safety system, whether a safety device should be activated.

Abstract: The present disclosure includes a manufactured seed comprising a seed shell and a restraint disposed within the seed shell. The seed shell is a structure having an open end and a closed end. The restraint comprises a parabolic cavity. A seal assembly is disposed on the open end of the seed shell in a configuration effective to seal the seed shell.

Abstract: We describe anhydride compounds suitable for physiologically labile modification of amine-containing molecules. The described anhydrides form reversible linkages having desirable kinetics for in vivo delivery of biologically active molecules. Also described are endosomolytic polymers formed by modification of membrane active polyamines with the described anhydrides.

Abstract: A cathodic member for electrochemical cells used in hypochlorite production comprises a zirconium plate coated with a zirconium oxide layer, which is particularly suitable for minimising the decomposition of the hypochlorite product while ensuring a prolonged lifetime. The coated zirconium plate can be used as the cathodic plate in a monopolar cell, or can be welded to a titanium plate for use in a bipolar configuration.

Abstract: A system is provided for improved steam generation. The system includes at least two steam systems, wherein a wet steam output from a first steam system is passed through a first separator. The first separator configured to separate dry steam from condensate, and a piping connection is configured to blend the condensate with a boiler feed water stream at the inlet of a second steam system.

Abstract: A steam system is provided that includes a steam generator including boiler tubes that are modified to form a number of intermediate take-offs for removing water and steam from the boiler tubes. A number of intermediate separators are provided to separate the water and steam at each of the intermediate take-offs. Intermediate couplings are used to inject the water back into the boiler tubes downstream of each of the plurality of intermediate take-offs.

Abstract: A container mounted on the top step of a stepladder has a bottom wall joined to upright walls providing a chamber for holding tools, paint cans, parts and supplies. A ledge joined to an upright wall has holes and a slot to retain additional tools. Releasable fasteners secure the bottom wall to the top step of a stepladder.

Abstract: The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted melittin delivery peptides. Delivery peptides provide membrane penetration function for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness to the delivery peptides.

Abstract: The present invention relates to ophthalmic compositions comprising inhibitors of spleen tyrosine kinase (syk). The compositions are particularly well suited for the treatment of ophthalmic infection such as fungal keratitis. The compositions optionally comprise an antiinfective compound such as an antibacterial or antifungal compound. The present invention also relates to methods for treating fungal keratitis using compositions comprising syk inhibitors.

Abstract: The present technology provides a rail crossing remote diagnostics system. The rail crossing remote diagnostics system includes a rail crossing station monitor installed in a bungalow at a rail crossing station. The station monitor has a communication module, such as a wireless transceiver, a connection to the ethernet, a cellular transceiver, a telephone connection, or a modem. The rail crossing remote diagnostics system also includes one or more diagnostic sensors installed at the rail crossing station. The diagnostic sensors are adapted to communicate with the station monitor. The station monitor automatically monitors at least one device installed at the rail crossing station and generates rail crossing diagnostics reports. The present technology also provides a rail crossing diagnostics network that includes a network hub and one or more rail crossing remote diagnostics systems. Certain embodiments also provide methods for automatically monitoring the operation of a rail crossing station.

Abstract: The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted melittin delivery peptides. Delivery peptides provide membrane penetration function for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness to the delivery peptides.

Abstract: Manufactured seeds are disclosed that comprise a unit of totipotent plant tissue and a nutritive medium. The nutritive medium can contain a number of different components selected from the following: a gel solute, charcoal, a carbon source, urea, KNO3, NH4NO3, CuCl2, CuSO4, KI, KH2PO4, CaCl2, MgSO4, Na2EDTA, FeSO4, ferric citrate, MnSO4, MnCl2, H3BO3, ZnSO4, CoCl2, Na2MoO4, (NH4)2MoO4, thiamine, riboflavin, pyridoxine, HCl, Ca-pantothenate, nicotinic acid, biotin, folic acid, and myo-inositol. The nutritive medium can also include any of various protein amino acids, any of various polyamines, any of various oxygen-absorbing compounds, any of various non-protein amino acids, and/or a smoke suspension.

Abstract: The present invention is directed compositions for delivery of RNA interference (RNAi) polynucleotides to cells in vivo. The compositions comprise amphipathic membrane active polyamines reversibly modified with enzyme cleavable dipeptide-amidobenzyl-carbonate masking agents. Modification masks membrane activity of the polymer while reversibility provides physiological responsiveness. The reversibly modified polyamines (dynamic polyconjugate or DPC) are further covalently linked to an RNAi polynucleotide or co-administered with a targeted RNAi polynucleotide-targeting molecule conjugate.

Abstract: Systems, methods, routines and/or techniques for a crossing gate tip sensor are described. According to one or more embodiments of the present disclosure, a crossing gate tip sensor may be attached to or incorporated into a gate arm of a crossing gate. The crossing gate tip sensor may accurately detect the orientation (among other things) of the gate arm. In some embodiments, a crossing gate tip sensor may include a tilt sensor that includes one or more accelerometers. In some embodiments, a crossing gate tip sensor may include a microcontroller and/or a wireless communication unit.

Abstract: The invention provides methods for improving germination of manufactured seeds. The manufactured seed of the invention comprises a seed coat, nutritive media comprising an adsorbent material in a concentration from about 30 g/L to about 100 g/L, and a shoot restraint comprising a cavity. The manufactured seed further comprises a plant embryo. The adsorbent material may be nutrient-treated or non-nutrient-treated charcoal. The manufactured seed may optionally contain an adsorbent material in the cavity of the shoot restraint.

Abstract: The present disclosure includes a shoot restraint for use with manufactured seeds comprising. In some embodiments, the shoot restraint includes a substantially porous material having a top surface and a bottom surface. The substantially porous material is formed to define a substantially cylindrical upper portion having an upper diameter; and a substantially cylindrical lower portion having a lower diameter. The upper diameter is larger than the lower diameter. A parabolic cavity extends from the top surface to the bottom surface through the upper portion and at least partially into the lower portion.