Abstract: A system for communicating between blockchains on heterogeneous blockchain networks. The system can include a sending blockchain configured to transmit a first message via a sending blockchain protocol, wherein the sending blockchain forms a part of a sending blockchain network. The system can include a sending adapter node configured to receive the first message from the sending blockchain and translate the first message from the sending blockchain protocol to an adapter protocol. The system can include a receiving adapter node configured to receive the first message from the sending adapter node and translate the first message from the adapter protocol to a receiving blockchain protocol. The system can include a receiving blockchain configured to receive the first message from the receiving adapter node, and validate the first message, wherein the receiving blockchain forms a part of a receiving blockchain network.

Abstract: Described herein are database systems including one or more remote analytical instruments operably connected to one or more servers. The instruments can transmit rich data to the servers, and the one or more servers can compile a database of the rich data. One or more processors associated with the servers can be configured to execute a data analytics program on the database to identify a stochastic phenomenon or to process the data and present in real-time at a location of the one or more instruments comparison information about the instruments.

Abstract: The present disclosure relates to guidewire devices having shapeable tips and effective torquability. A guidewire device includes a core having a proximal section and a tapered distal section. A tube structure is coupled to the core such that the tapered distal section extends into the tube structure. The tube structure includes a plurality of bypass cuts formed tangentially within the tube structure to increase the flexibility of the tube structure and to reduce the tendency of resilient forces from the tube structure to disrupt a shaped distal tip of the guidewire device.

Abstract: A thermostatic valve assembly for an internal combustion engine cooling system. The thermostatic valve assembly including a valve housing and a plunger assembly. The valve housing includes a chamber, an inlet port, a radiator output port, and a bypass output port. The bypass output port including a flow opening. The plunger assembly being slideably secured within the chamber and moving between a first position to close the flow opening and a second position to open the flow opening. The plunger assembly comprises a body and at least one seal configured to seal the flow opening when in the first position.

Abstract: Techniques are provided herein to form semiconductor devices that include a gate cut formed after the formation of source/drain contacts. In an example, a semiconductor device includes a gate structure around or otherwise on a semiconductor region that extends from a source region to a drain region. Conductive contacts formed over the source and drain regions along a source/drain trench. The gate structure may be interrupted with a dielectric gate cut that further extends past the gate trench and into the source/drain trench where it can cut into one or more of the contacts. The contacts are formed before the gate cut to ensure complete fill of conductive material when forming the contacts. Accordingly, a liner structure on the conductive contacts is also broken by the intrusion of the gate cut and does not extend further up or down the sidewalls of the gate cut.

Abstract: Techniques are provided to form semiconductor devices that include one or more gate cuts having a layer of polymer material at edges of the gate cut. The polymer layer may be provided as a byproduct of the etching process used to form the gate cut recess through the gate structure, and can protect any exposed portions of the source or drain regions from certain subsequent processes. The gate structure may be interrupted between two transistors with a gate cut that extends through an entire thickness of the gate structure and includes a dielectric material to electrically isolate the portions of the gate structure on either side of the gate cut. The edges of the gate cut may be lined with a polymer layer that is also on any exposed portions of the source or drain regions that were exposed during the etching process used to form the gate cut recess.

Abstract: An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images.

Abstract: Rifle scopes with a locking feature including a body having an internal movable optical adjustor adapted to shift an image generated by the riflescope, a knob connected to the body for rotation about a knob axis and operably connected to the optical adjustor to position the optical adjustor based on a rotational position of the knob, an indicator skirt rotatably engaged to the body and threadedly engaged to the knob, the indicator skirt being operable to move axially with respect to the knob such that the axial position of the indicator skirt is based on the rotational position of the knob, and the knob including a knob stop surface and the indicator skirt including a skirt stop surface, wherein the knob stop surface and the skirt stop surface are configured to positively contact each other to establish a limit of rotational travel of the knob.

Abstract: Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a medical device includes an occluder portion and an anchor portion. The occluder portion includes a hub that defines an axis, the occluder portion extending between a proximal end coupled to the hub and a distal end defining an occluder eyelet adjacent thereto. The anchor portion extends between a first end and a second end, the first end coupled to an anchor hub and the second end defining an anchor eyelet adjacent thereto and hingeably coupled to the occluder eyelet. With this arrangement, the anchor hub is moveable along the axis to move the anchor portion between a retracted position and a deployed position upon the occluder portion being in an expanded position.

Abstract: A variable dose dispensing system may include a processor and memory. The processor secures a first container including a first dosage form of medication in a first location and a second container including a second dosage form of the medication in a second location within an automated dispensing device. The processor also receives a selection identifying an order for the medication, the order including at least a maximum amount to administer and determines that the first dosage form and the second dosage form are sufficient to provide the maximum amount. The processor also selects the first dosage form as preferable over the second dosage form based on one or more determined characteristics of the first dosage form and of the second dosage form and activates the automated dispensing device to permit access to the first location.

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: A method for moderation in a permissioned blockchain using a hash-oriented scheme includes: storing a blockchain including a most recent block; receiving transaction data values; receiving a first reference value and a second reference value; generating a first hash value by hashing the first reference value; generating a block proof including the first hash value, a second hash value, a third reference value, and a block value; verifying a block header of the most recent block using the block proof; receiving a new block value; generating a new block header including the first reference value, the second reference value, a fourth reference value, and the new block value; generating a new block for the blockchain including the new block header and the transaction data values; and transmitting the new block to one or more additional nodes associated with the blockchain.

Abstract: A paintbrush guard a hollow body sized to fit over a felt of a paintbrush, a pair of opposing side shields and end shields extending from the body, the side shields having a plurality of interlocking tabs which can be used to lock the shields in an open bell shaped position or a closed position for cutting in a painted surface. The paintbrush guard may also be equipped with a downward facing hook extending from an end shield to hold the guard and paintbrush on the side of a paint container. Further the paintbrush guard maybe equipped with a comb on the side of the guard for use in cleaning a paintbrush.

Abstract: A method of one aspect may include receiving a rotate instruction. The rotate instruction may indicate a source operand and a rotate amount. A result may be stored in a destination operand indicated by the rotate instruction. The result may have the source operand rotated by the rotate amount. Execution of the rotate instruction may complete without reading a carry flag.

Abstract: A system for enabling communication between blockchains on heterogeneous blockchain networks. The system can include a sending blockchain network comprised of a sending blockchain that includes a plurality of blocks, each block including a block header and one or more transaction values associated with an identification request transmitted by the sending blockchain. The system can include a directory service node configured to receive the identification request from the sending blockchain, and identify a receiving blockchain, which forms part of a receiving blockchain network. The system can include an identity service node configured to receive a trust request from the directory service node to determine whether a valid trust certificate is available for the receiving blockchain, and enable communication between the sending blockchain and the receiving blockchain, when the valid trust certificate is determined to be available.

Abstract: Rifle scopes with a locking feature including a body having an internal movable optical adjustor adapted to shift an image generated by the riflescope, a knob connected to the body for rotation about a knob axis and operably connected to the optical adjustor to position the optical adjustor based on a rotational position of the knob, an indicator skirt rotatably engaged to the body and threadedly engaged to the knob, the indicator skirt being operable to move axially with respect to the knob such that the axial position of the indicator skirt is based on the rotational position of the knob, and the knob including a knob stop surface and the indicator skirt including a skirt stop surface, wherein the knob stop surface and the skirt stop surface are configured to positively contact each other to establish a limit of rotational travel of the knob.

Abstract: Integrated power modules according to the present technology may include a printed circuit board characterized by a first surface and a second surface. The integrated power modules may include one or more surface-mounted components coupled with the first surface of the printed circuit board. The integrated power modules may include a heat-transfer substrate. The integrated power modules may include one or more gallium nitride transistors coupled between and soldered to each of the second surface of the printed circuit board and the heat-transfer substrate. The integrated power modules may include one or more spacers coupled between and soldered to each of the printed circuit board and the heat-transfer substrate.

Abstract: A method for verification of a data value via a Merkle root includes: storing, in a memory of a processing server, a Merkle root; receiving at least a data value, a nonce, and a plurality of hash path values; generating a combined value by combining the data value and the nonce; generating a first hash value via application of a hashing algorithm to the combined value; generating a subsequent hash value via application of the hashing algorithm to a combination of the first hash value and a first of the plurality of hash path values; repeating generation of the subsequent hash value using a combination of the next hash path value of the plurality of hash path values and the most recent subsequent hash value; and verifying the data value based on a comparison of the Merkle root and the last generated subsequent hash value.

Abstract: The invention provides compositions and methods useful for mobilizing populations of hematopoietic stem and progenitor cells within a donor, as well as for determining whether samples of mobilized cells are suitable for release for ex vivo expansion and/or therapeutic use. In accordance with the compositions and methods described herein, mobilized hematopoietic stem and progenitor cells can be withdrawn from a donor and administered to a patient for the treatment of various stem cell disorders, including hematological, among others.

Abstract: A method for maintaining a consistent blockchain ledger for storing commitments across multiple separate blockchains includes: storing a blockchain comprised of a plurality of blocks, each block including at least a block header and one or more blockchain data values; receiving a base commitment from a first node, where the first node is included in a first blockchain network; generating a first new block including at least a first block header and the received base commitment; storing the first new block in the blockchain; receiving a state commitment from an additional node included in each of at least two additional blockchain networks; generating an additional new block including at least an additional block header and each received state commitment; and storing the additional new block in the blockchain.