Abstract: This present disclosure relates to a designed material surface mimicking properties of an extracellular matrix or matrisome, as a means for modulating cell adhesion, spreading, proliferation, differentiation, or reprogramming; and for controllable, directional cell adhesion, spreading, proliferation, differentiation, or reprogramming. In particular, this present disclosure relates to a designed material surface mimicking properties of large polysaccharides for modulating cell adhesion, proliferation, differentiation, or reprogramming of a cell, and to materials for scaffolding cell growth. Processes and composition matters are within the scope of this patent application.

Abstract: A device to measure the voltage at a test point, also referred to as a test point voltage sensor, comprises a housing formed from a first material and a second material, wherein the first material comprises an insulating material and the second material comprises a conductive or semiconductive material. The housing includes an opening configured to cover a test point of a cable accessory. The device further includes a pressure pad, disposed in the housing, having a conductive mating surface configured to contact a test point of the basic insulation plug or end plug. The device further includes a low side capacitor embedded in the housing and electrically coupled to the conductive mating surface. The device further includes a signal wire electrically coupled to the low side capacitor.

Abstract: Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a delivery system for use in occluding an opening in the tissue of a body includes an actuation assembly operatively coupled to a medical device including an anchor portion and an occluder portion. The actuation assembly is configured to move the anchor portion between a deployed state and retracted state while the occluder portion maintains a deployed state. With this arrangement, the deployed occluder portion can be visualized via imaging at a preferred position prior to deploying the anchor portion of the medical device.

Abstract: A method and apparatus for a locking system for a downhole tool. The locking system includes a first portion having a plurality of displaceable members, a second portion disposed around the first portion; a locked position wherein axial movement between the members is prevented; and an unlocked position wherein axial movement between the members is permitted.

Abstract: An approach is provided for deterring a tampering of content. Content is signed by using an asymmetric key cryptography. The signed content is stored in a distributed ledger which is accessible to a plurality of subscribers of the distributed ledger. The signing of the content using the asymmetric key cryptography together with the storing of the signed content in the distributed ledger provide a non-repudiable identification of an owner of the content and a non-repudiable proof of an ownership of the content.

Abstract: Rifle scopes with zero locks or stops have a body having an internal movable optical adjustor adapted to shift an image generated by the riflescope, a knob connected to the body for rotation about a knob axis and operably connected to the optical adjustor to position the optical adjustor based on a rotational position of the knob, an indicator skirt rotatably engaged to the body and threadedly engaged to the knob, the indicator skirt being operable to move axially with respect to the knob such that the axial position of the indicator skirt is based on the rotational position of the knob, and the knob including a knob stop surface and the indicator skirt including a skirt stop surface, wherein the knob stop surface and the skirt stop surface are configured to positively contact each other to establish a limit of rotational travel of the knob.

Abstract: A caul for debulking a composite part broadly includes opposing first and second surfaces, a plurality of through-holes, and a coating. The first surface may have a curvature complementary to a shape of the composite part. The through-holes pass through the caul from the first surface to the second surface. The coating may be a chemically inert material to ensure the caul does not affect the composite part. The caul is configured to be positioned against the composite part for debulking. The caul may be made out of silicone rubber or any other suitable material and may be reusable.

Abstract: A method for recovery of missing or extra data using a bloom filter includes: storing a plurality of transaction messages, each including a transaction value; generating a bloom filter of the transaction messages, the bloom filter being generated using a number of hash rounds and with a size at least double the number of transaction messages; generating a recover message including the number of transaction messages, the number of hash rounds, the size, and the generated bloom filter; transmitting the recover message to a consensus node; receiving a response message from the consensus node, the response message including at least one additional transaction message; and inserting the at least one additional transaction message into the plurality of transaction messages.

Abstract: A method for providing consent for provisioning data in an opaque blockchain, includes: receiving, by a receiver of a processing server, a consent request for data associated with the processing server stored on a blockchain, the consent request including at least two digital signatures, where a first digital signature is generated by a regulating entity and a second digital signature is generated by a moderating entity in the blockchain network; validating, by a processing device of the processing server, the first digital signature and the second digital signature; digitally signing, by the processing device of the processing server, the received consent request using a private key of a first cryptographic key pair; and transmitting, by a transmitter of the processing server, the digitally signed consent request to the regulating entity.

Abstract: A diamondoid fuel comprising a cage structure including 10, 14, 18, or 22 carbons. The diamondoid fuel also includes one of one to four cyclopropyl groups bonded to the cage structure or two to four functional groups bonded to the cage structure where the functional groups are an alkyl group, an allyl group, a cyclopropyl group, or combinations thereof. Additionally, at least one functional group is an allyl group and at least one functional group is a cyclopropyl group.

Abstract: The present invention generally relates to a method for creating a chemically structured surface with structural elements as small as 1 nm, on a material that does not itself display a high degree of ordering, using thin molecular layers that minimize the material added through the coating. In particular, the present invention discloses a method for assembling a chemical pattern on a surface, comprising pattern elements with scales that can be as small as 1 nm, and then transferring that pattern to another substrate, on which the pattern would not form natively. In the described method, the patterned monolayer is comprised of polymerizable amphiphiles such as diyne phospholipids or diynoic acids, which are transferred from the ordering substrate using a transferring material such as poly(dimethylsiloxane).

Abstract: Described herein are database systems including one or more remote analytical instruments operably connected to one or more servers. The instruments can transmit rich data to the servers, and the one or more servers can compile a database of the rich data. One or more processors associated with the servers can be configured to execute a data analytics program on the database to identify a stochastic phenomenon or to process the data and present in real-time at a location of the one or more instruments comparison information about the instruments.

Abstract: Novel cell penetrating agents for intracellular delivery of desired cargo, including proteins. Use of cell penetrating agents to deliver cargos to the interior of cells and cellular compartments and organelles is transformative for diagnostic, therapeutic, and research processes.

Abstract: A method for making thermosetting polyimides from resveratrol including converting resveratrol to trisaniline, reacting trisaniline with one or more dianhydride and thermosetting endcap to form amic acid, thermally imidizing amic acid to form polyimide oligomer, and cross-linking polyimide oligomer with heat and pressure to generate polyimide thermoset.

Abstract: A computer-implemented method for migrating a monolithic legacy software system to a well-defined modular target software architecture includes selecting a method, based on predefined patterns, for transforming the software legacy software system; creating an abstract syntax tree from the legacy software system's source code; from the abstract syntax tree, determining a flow of the source code and any coding violations and coding smells in the legacy software system's source code; using the flow and the coding violations, identifying architecture issues in the legacy software system; scheduling tasks for transforming the legacy software system into the target software architecture; automatically generating new source code according to the target software architecture; and automatically and autonomously refactoring the new source code.

Abstract: A computer-implemented method according to one embodiment includes performing a first process for each chunk of data of each file of a snapshot of a file system. The first process includes reading a given chunk of data of a given file of a first snapshot of the file system, and reading shadow records of a shadow file of the first snapshot. The given chunk of data is compared with the shadow records for determining whether a coherent state exists between the given chunk of data and one or more of the shadow records that were recorded in a snapshot creation window. In response to determining that no coherent state exists, an indication is recorded that the given chunk of data is corrupt. In response to determining that a coherent state exist, an indication is recorded that the given chunk of data is accurate.

Abstract: A computer-implemented method, system and computer program product for improving query searches. After receiving a query from a user to conduct a content search, the query is analyzed for its semantic meaning and a categorized group of query tags and content tags in the central repository that is most semantically similar in meaning to the meaning of the query is identified. Furthermore, the content tags and query tags in the user's repository are analyzed to determine the interests of the user. The query may then be augmented to include one or more other terms of interest from the identified categorized group of query tags and content tags in the central repository that match the determined interests of the user within a threshold degree of relatedness, where these other terms of interest correspond to the content tags and query tags of the identified categorized group based on their assigned weight.

Abstract: A method for generation of blocks for a partitioned blockchain includes: storing blocks comprising a partitioned blockchain, wherein each block includes a header and transaction entries; receiving transaction data entries for each of a plurality of subnets; generating a hash value of the header included in the most recently added block; generating a new block header, the new block header including the generated hash value, a timestamp, and a sequence of pairs including a pair for each of the plurality of subnets, each pair including a subnet identifier associated with the respective subnet and a merkle root of each of the transaction data entries received for the respective subnet; generating a new block, the new block including the generated new block header and the transaction data entries for each of the plurality of subnets; and transmitting the new block to a plurality of nodes associated with the partitioned blockchain.

Abstract: Several embodiments are set forth of devices, systems and methods for modifying an atrial appendage such as a left atrial appendage (LAA). In one embodiment, a medical device includes a frame member and a tissue growth member. The frame member includes a unitary, seamless central portion having a plurality of struts defining a multi-cellular structure and an anchoring system, the plurality of struts extending between and configured to self-expand and directly bias the anchor system to anchor the frame member at least partially within the LAA. With this arrangement, the tissue growth member is attached to the frame member to occlude the LAA.

Abstract: A method and system for representing scalar digital assets using hash chains may include a processor which may receive a data request for one or more units of a scalar digital asset from a computing device. The processor may identify the scalar digital asset requested by the computing device and the one or more units of the scalar digital asset. The processor may verify the computing device has access to the scalar digital asset. The processor may generate a hash chain of the one or more units of the scalar digital asset and transmit a data response message containing the hash chain of the one or more units of the scalar digital asset to the computing device.