Abstract: A hosted web-accessible system, computer program and methods are provided for generating comprehensive vehicle trim and detailed equipment information for clients, including providing comparative estimation based on underlying information regarding a particular vehicle. Comprehensive original vehicle data is obtained from vehicle manufacturers via a vehicle source interface, the data including a unique vehicle identifier for each of one or more vehicles associated with the respective source. A vehicle information request with a vehicle identifier is received from a client, and comprehensive original vehicle data is identified based on the unique identifier and the identifier from the client request. A client response interface displays vehicle data from the identified set of comprehensive original vehicle data. Vehicle valuation may be obtained from third party evaluators according to the vehicle request and based on the original vehicle data.

Abstract: Ultrasonic surgical instruments including a handle housing, a switch frame, and a switch assembly are disclosed. The switch assembly may include a first switch arrangement movably supported on a distal portion of the handle housing and selectively movable relative to a first switch contact supported by the switch frame. The switch assembly may further include a second switch arrangement including a right switch button movably supported on a right side of the handle housing and selectively movable relative to a right switch contact supported by the switch frame, and a left switch button movably supported on a left side of the handle housing and selectively movable relative to a left switch contact supported by the switch frame. The first and second switch arrangements may be configured to be selectively actuatable by a single hand supporting the handle housing.

Abstract: Apparatuses and methods for delivering a fluid, including a viscous fluid. These apparatuses may include a fluid reservoir, two or more piston chambers, a manifold, a delivery port, and a drive assembly and may be configured to inject either a predetermined amount of fluid or a continuous stream of fluid. These apparatuses may also be configured to switch between filling, injection and aspiration modes. These apparatuses may generally be hand-held and lightweight and may provide a significant mechanical advantage to the user.

Abstract: Medicaments for use in treating T-cell acute lymphoblastic leukemia, acute lymphoblastic leukemia, acute myelogenous leukemia, chronic myelogenous leukemia, breast cancer, ovarian cancer, melanoma, lung cancer, pancreatic cancer, glioblastoma, sarcoma, desmoid tumors, adenoid cystic carcinoma, colorectal cancer, head and neck cancer, cervical cancer, prostate cancer, liver cancer, or skin cancer in a patient comprising combination therapy with 4,4,4-trifluoro-N-[(1S)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]butanamide, or a pharmaceutically acceptable salt or hydrate thereof, and 8-[5-(1-hydroxy-1-methylethyl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one, or a pharmaceutically acceptable salt thereof.

Abstract: An agility course for use with an animal can include an obstacle, and a sensor configured to detect when the animal has traversed the obstacle. A method of training an animal can include positioning an obstacle unit and a dispenser unit so that a wireless signal can be transmitted from the obstacle unit to the dispenser unit, and transmitting the wireless signal in response to the animal traversing an obstacle of the obstacle unit.

Abstract: An optical obturator apparatus includes an obturator sleeve defining a longitudinal axis and having a longitudinal bore for receiving surgical instrumentation and a transparent window mounted to the obturator sleeve and being dimensioned and configured to pass through tissue. The transparent window is mounted for movement between a first position in general alignment with the longitudinal axis of the obturator sleeve and a second position radially displaced from the longitudinal axis to thereby expose the longitudinal bore of the obturator sleeve to permit passage of the surgical instrumentation. The transparent window may include a cutting blade, or alternatively two cutting blades, adapted to penetrate tissue.

Abstract: An electrically insulating gas composition comprises C3F7CN, in an amount between 22% and 70% by volume and one or more inert gas selected from the list consisting of nitrogen, carbon dioxide (CO2), air and argon.

Abstract: A timed or remotely operated wildlife feeder which delivers feed such as whole fruit and nuts by emptying feed storage containers into a chute to deliver feed using potential energy and gravity instead of kinetically broadcasting the feed.

Abstract: A variety of active cover plate configurations with prongs configured to contact side screw terminals of electrical receptacles are described.

Abstract: Techniques have been developed to facilitate the livestreaming of group audiovisual performances. Audiovisual performances including vocal music are captured and coordinated with performances of other users in ways that can create compelling user and listener experiences. For example, in some cases or embodiments, duets with a host performer may be supported in a sing-with-the-artist style audiovisual livestream in which aspiring vocalists request or queue particular songs for a live radio show entertainment format. The developed techniques provide a communications latency-tolerant mechanism for synchronizing vocal performances captured at geographically-separated devices (e.g., at globally-distributed, but network-connected mobile phones or tablets or at audiovisual capture devices geographically separated from a live studio).

Abstract: The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes.

Abstract: Devices, systems, and methods for explosion resistance include an analysis compartment isolated from a control compartment. A feed-through extends between the analysis compartment and the control compartment for extension of cabling therethrough, the feed-through hermetically sealed to block against flow of fluids between the analysis and control compartments.

Abstract: User interface techniques provide user vocalists with mechanisms for seeding subsequent performances by other users (e.g., joiners). A seed may be a full-length seed spanning much or all of a pre-existing audio (or audiovisual) work and mixing, to seed further contributions of one or more joiners, a user's captured media content for at least some portions of the audio (or audiovisual) work. A short seed may span less than all (and in some cases, much less than all) of the audio (or audiovisual) work. For example, a verse, chorus, refrain, hook or other limited “chunk” of an audio (or audiovisual) work may constitute a seed. A seeding user's call invites other users to join the full-length or short-form seed by singing along, singing a particular vocal part or musical section, singing harmony or other duet part, rapping, talking, clapping, recording video, adding a video clip from camera roll, etc.

Abstract: Techniques have been developed to facilitate the livestreaming of group audiovisual performances. Audiovisual performances including vocal music are captured and coordinated with performances of other users in ways that can create compelling user and listener experiences. For example, in some cases or embodiments, duets with a host performer may be supported in a sing-with-the-artist style audiovisual livestream in which aspiring vocalists request or queue particular songs for a live radio show entertainment format. The developed techniques provide a communications latency-tolerant mechanism for synchronizing vocal performances captured at geographically-separated devices (e.g., at globally-distributed, but network-connected mobile phones or tablets or at audiovisual capture devices geographically separated from a live studio).

Abstract: Techniques have been developed to facilitate (1) the capture and pitch correction of vocal performances on handheld or other portable computing devices and (2) the mixing of such pitch-corrected vocal performances with backing tracks for audible rendering on targets that include such portable computing devices and as well as desktops, workstations, gaming stations, even telephony targets. Implementations of the described techniques employ signal processing techniques and allocations of system functionality that are suitable given the generally limited capabilities of such handheld or portable computing devices and that facilitate efficient encoding and communication of the pitch-corrected vocal performances (or precursors or derivatives thereof) via wireless and/or wired bandwidth-limited networks for rendering on portable computing devices or other targets.

Abstract: A seal assembly including a septum seal, a lower seal support, an upper seal support and a return spring is disclosed. The septum seal includes an orifice and a plurality of apertures. The lower seal support includes an engagement surface configured to engage a portion of the septum seal. The upper seal support includes a plurality of fingers, wherein each of the plurality of fingers is configured to extend through a corresponding aperture of the septum seal. The return spring includes a collar portion and a plurality of spokes extending radially outward from the collar portion. At least a portion of the return spring may be sandwiched between the lower seal support and the upper seal support. The plurality of spokes is configured to bias the seal assembly toward a radial center of a housing.

Abstract: Devices, systems, and methods for explosion resistance include an analysis compartment isolated from a control compartment. A feed-through extends between the analysis compartment and the control compartment for extension of cabling therethrough, the feed-through hermetically sealed to block against flow of fluids between the analysis and control compartments.

Abstract: Devices, systems, and methods for explosion resistance include an explosion-resistant enclosure and a lid assembly. The lid assembly includes a lid for enclosing an opening of the explosion-resistant enclosure, and a graphical display assembly for presenting visual information regarding the analysis equipment.

Abstract: A micro-turbine core fabricated as a single part using 3D additive manufacturing (AM) to simultaneously form sequential layers of at least two static components from any of the following static components: central bearing support structure, outer casing, combustor complete, nozzle guide vanes (NGVs), diffuser, diffuser outer casing, fuel manifold, fuel injector(s), igniter mounting boss, oil manifold, oil distribution lines, or turbine outer casing. The single part does not require fastening hardware, welding, and/or bonding processes to create the single part.

Abstract: Disclosed herein are methods, formulations, and kits for treating coronavirus infections, including Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infections and SARS-CoV-2 infections. Further disclosed are stop-gap methods for controlling the spread of coronavirus infections and the emergence of drug resistant strains of coronavirus.