Abstract: A microfluidic device includes a particle sorting region having a first, second and third microfluidic channels, a first array of islands separating the first microfluidic channel from the second microfluidic channel, and a second array of islands separating the first microfluidic channel from the third microfluidic channel, in which the island arrays and the microfluidic channels are arranged so that a first fluid is extracted from the first microfluidic channel into the second microfluidic channel and a second fluid is extracted from the third microfluidic channel into the first microfluidic channel, and so that particles are transferred from the first fluid sample into the second fluid sample within the first microfluidic channel.

Abstract: Systems and methods for continuous injection of fluid, in some examples these apparatuses may include a manifold, a pair of reciprocating pistons, and an actuation control that may apply both suction (aspiration) and injection of fluid as part of the same actuation. The systems and methods may be configured to simplify the operation of a continuous fluid injection system, including one that aspirated prior, to injection to confirm the absence/presence of blood.

Abstract: A vertical panel door stacking system for a door having panels with end caps coupled thereto. The end caps include a body portion, a cam lever to rotate around an axis to generate a lift force to lift and separate an adjacent pair of panels of the panels of the door, a first track wheel, a second track wheel, and a third track wheel. The track wheels interact with a track system to guide movement of the door panels between a closed position and an open position.

Abstract: The disclosure relates to modulating pyruvate kinase and provides novel chemical compounds useful as activators of PKR, as well as various uses of these compounds. PKR activating compounds are useful in the treatment of diseases and disorders associated with PKR and/or PKM2, such as pyruvate kinase deficiency (PKD), sickle cell disease (SCD), and thalassemia.

Abstract: A digital display of an active window is provided. An application, separate from the application providing the digital display, is capable of identifying an artifact in the active window of the digital display without a priori knowledge or an application programming interface to the application providing the digital display. The artifacts may be alpha-numeric artifacts or non-alpha-numeric artifacts. The active window may be examined in multiple dimensions including 2 dimensions, 3 dimensions or more. Alpha-numeric artifacts, once identified, are pre-processed to remove anti-aliasing to allow for processor optical recognition.

Abstract: In example implementations, a horizontal door guide for a vertically stacking door is provided. The horizontal door guide includes a first track and a second track to vertically stack panels of a door along a horizontal line, a drive shaft coupled to a bottom most panel to lift the door vertically, a Geneva drive shaft coupled to the drive shaft, and a lifting cam coupled to the Geneva drive shaft, wherein the lifting cam comprises a rotating lever to separate and lift adjacent panels of the door as the door is opened in a vertical direction by the drive shaft and to push panels into the first track and the second track.

Abstract: Described herein are devices and methods for pumping blood in a patient in need of circulatory assistance or a replacement heart. Instead of providing a temporary solution for these patients, the devices may be permanently implanted. The devices linearly reciprocate a shuttle within a housing to move blood into and out of the housing, and rotate the shuttle to selectively direct the movement of blood into and out of a plurality of ports in the housing.

Abstract: Disclosed herein is a web user experience improvement for digital magazines. A digital magazine viewing platform is integrated with a digital magazine publishing platform including features that leverage the integration including user interface arrangement based on viewing habits and ripped content that is insertable into draft digital magazine documents. In some embodiments, a machine learning model categorizes magazine styles and present publishing features based on those magazines viewed or subscribed to by a given user.

Abstract: An under hood storage system of a vehicle includes an under hood storage compartment located in an under hood area of a vehicle, and a hood assembly that, when in a closed position closes the under hood storage compartment. The hood assembly includes an under hood panel having a first portion formed from a first material, and a second portion surrounding the first portion defining an outer perimeter of the under hood panel. The second portion is formed from a second material softer than the first material. One or more attachment features secure the under hood panel to the hood assembly. The under hood panel interacts with the under hood storage compartment to close the under hood storage compartment.

Abstract: Processes for producing n-heptane from a mixture of 1-hexene and 1-octene in the presence of a suitable isomerization-metathesis catalyst followed by a hydrogenation step are disclosed. Integrated manufacturing systems for producing n-heptane with minimal waste also are disclosed.

Abstract: A variety of active cover plate configurations with prongs configured to contact side screw terminals of electrical receptacles are described.

Abstract: At least one server comprising at least one processor coupled to at least one memory storing instructions. The server can receive a first signal from a first monitored system comprising an internal combustion engine and a first sensor, the first signal associated with a first occurrence of an internal combustion engine event, a second occurrence of the internal combustion engine event, and first measurement data of the first sensor. The server can determine a first measurement from the first measurement data. The server can determine a second measurement from the first measurement data. The server can determine a measurement deviation between the first measurement and the second measurement. The server can compare the measurement deviation to a stored measurement threshold. The server can determine a first exhibited useful life of the first sensor based on the measurement deviation and at least one of the first measurement or the second measurement.

Abstract: A system for physical rehabilitation is disclosed. The system comprises a plurality of motors configured to be coupled to a ceiling, and a plurality of cable portions. Each cable portion is connected at a first end to a motor, among the plurality of motors, and connected at a second end to a connector element for attaching to a patient. The system also comprises a controller in operative communication with the plurality of motors to move the connector element in relation to a staircase. The controller is configured to adjust one or both of position and speed of the connector element based on tracked kinematics of the patient as the patient moves along the staircase.

Abstract: In example implementations, a track system of a vertically stacking door includes a vertical track, a track coupling coupled to the vertical track, a first curved track portion coupled to the track coupling, a second curved track portion coupled to the track coupling, and a ramp coupled to the vertical track. The ramp interacts with a cam lever to separate adjacent panels of the vertically stacking door.

Abstract: System (100) for accommodating mobile devices used for video teleconferencing, the system including a loudspeaker (120), a controller (190), and an elevated support (140) for the mobile device. The controller communicates with the mobile device and controls the loudspeaker to provide an audio interface with the mobile device.

Abstract: Methods and apparatus to estimate census-level audience sizes and duration data across dimensions and/or demographics are disclosed. An example apparatus includes constraint equation control circuitry to select at least one constraint equation corresponding to one or more events, the one or more events corresponding to first audience members and second audience members, the first audience members to include the second audience members, constraint parameter estimation circuitry to solve the at least one constraint equation to determine one or more constraint parameter values, the one or more constraint parameter values corresponding to the one or more events, and output generation circuitry to determine, based on one or more intermediate equations and the one or more constraint parameter values, an event audience size and an event duration corresponding to (a) the first audience members and (b) a combination of the one or more events and one or more demographics.

Abstract: A variety of active units that sense environmental variables and take various actions are described. In one embodiment, an active unit includes at least one sensor to detect a change in an environmental variable and generate a sensor signal and an action module configured to influence the environmental. The active unit may also include a communication module and a processor module configured to accept the sensor signal and determine if the environmental variable exceeds a threshold and to instruct the action module not to take action to influence the environmental variable, and instruct the communication module to transmit a signal to other active units that the environmental variable has exceeded the threshold.

Abstract: A digital display of an active window is provided. An application, separate from the application providing the digital display, is capable of identifying an artifact in the active window of the digital display without a priori knowledge or an application programming interface to the application providing the digital display. The artifacts may be alpha-numeric artifacts or non-alpha-numeric artifacts. The active window may be examined in multiple dimensions including 2 dimensions, 3 dimensions or more. Alpha-numeric artifacts, once identified, are pre-processed to remove anti-aliasing to allow for processor optical recognition.

Abstract: A ventilation system for a space includes an air supply partition configured to cause filtered air to flow into an area of the space, and an air exhaust partition in spaced-apart relationship with the air supply partition and configured to cause air to be drawn in and filtered from the area. The air supply partition and the air exhaust partition create a “push-pull” air flow across the area. A ventilation partition includes air inlets in a first portion of the housing, air outlets in a second portion of the housing, a filter, and a fan configured to draw air in through the air inlets, through the filter, and out through the air outlets. The partition is a portable, free-standing structure configured to be supported by a surface, such as a floor of a room in which the partition is located.

Abstract: Disclosed herein is a web user experience improvement for digital magazines. A digital magazine viewing platform is integrated with a digital magazine publishing platform including features that leverage the integration including automated generation of digital magazine documents from a set of input images and search engine crawlable magazine presentation pages, a machine learning model categorizes magazine styles and present publishing features based on those magazines viewed or subscribed to by a given user.