Patents by Inventor Carl A. Brooks

Carl A. Brooks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10968209
    Abstract: The present invention relates to a novel compound useful as a TRPV4 antagonist, specifically the compound 1-(((5S,7R)-3-(5-cyclopropylpyrazin-2-yl)-7-hydroxy-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl)methyl)-1H-benzo[d]imidazole-6-carbonitrile, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compound.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: April 6, 2021
    Inventors: Patrick Stoy, Carl A. Brooks, Guosen Ye
  • Publication number: 20210093794
    Abstract: A power injector system having a power injector for enabling delivery of fluid in an injection procedure to be performed on a patient may include one or more processors; a first user interface; and a second user interface. The first user interface and the second user interface may be configured to accept a plurality of user inputs associated with control of a plurality of operations of the power injector system and display information associated with the plurality of operations. One of the first user interface and the second user interface may be proximate to the power injector and the other may be remote from the power injector. The one or more processors may be programmed and/or configured to independently control the first user interface and the second user interface based on a first user input and a next user input received from the first user interface and/or the second user interface.
    Type: Application
    Filed: April 9, 2019
    Publication date: April 1, 2021
    Inventors: JOHN VOLKAR, COREY KEMPER, SOMESHWAR MUKHERJEE, SAMANTHA PARKER, CARL BENSON, JAMES HOON YOO, LEONA MULCAHY, MICHAEL BROOKS, RICHARD SOKOLOV, BENJAMIN JAMES CULLEN, ALISON RUTH VON MOGER
  • Publication number: 20200308160
    Abstract: The present invention relates to a novel compound useful as a TRPV4 antagonist, specifically the compound 1-(((5S,7R)-3-(5-cyclopropylpyrazin-2-yl)-7-hydroxy-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl)methyl)-1H-benzo[d]imidazole-6-carbonitrile, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compound.
    Type: Application
    Filed: May 18, 2017
    Publication date: October 1, 2020
    Inventors: Patrick STOY, Carl A. BROOKS, Guosen YE
  • Publication number: 20200261411
    Abstract: The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
    Type: Application
    Filed: February 21, 2020
    Publication date: August 20, 2020
    Inventors: Edward J. BRNARDIC, Carl A. BROOKS, Brian Griffin LAWHORN, Guosen YE, Linda S. BARTON, Brian W. BUDZIK, Jay M. MATTHEWS, John Jeffrey McATEE, Jaclyn R. PATTERSON, Joseph E. PERO, Robert SANCHEZ, Matthew Robert SENDER, Lamont Roscoe TERRELL, David J. BEHM, James V. THOMAS
  • Patent number: 10590077
    Abstract: The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: March 17, 2020
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Edward J. Brnardic, Carl A. Brooks, Brian W. Budzik, Brian Griffin Lawhorn, Jay M. Matthews, John Jeffrey McAtee, Joseph E. Pero, David J. Behm
  • Patent number: 10588891
    Abstract: The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: March 17, 2020
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Edward J. Brnardic, Carl A. Brooks, Brian Griffin Lawhorn, Guosen Ye, Linda S. Barton, Brian W. Budzik, Jay M. Matthews, John Jeffrey McAtee, Jaclyn R. Patterson, Joseph E. Pero, Robert Sanchez, Matthew Robert Sender, Lamont Roscoe Terrell, David J. Behm, James V. Thomas
  • Publication number: 20200031846
    Abstract: The present invention relates to a compound which is (R)-3-(1,4-dimethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((R)-2-ethyl-2,3-dihydropyrido[2,3-f][1,4]oxazepin-4(5H)-yl)methyl)-4-methylphenyl)propanoic acid (I), or a pharmaceutically acceptable salt thereof, in particular, the meglumine salt thereof, a pharmaceutical composition containing the compound and its use as an NRF2 activator.
    Type: Application
    Filed: December 11, 2017
    Publication date: January 30, 2020
    Inventors: Carl A. BROOKS, Jay M. MATTHEWS
  • Publication number: 20190216774
    Abstract: The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
    Type: Application
    Filed: September 20, 2017
    Publication date: July 18, 2019
    Inventors: Edward J. BRNARDIC, Carl A. BROOKS, Brian Griffin LAWHORN, Guosen YE, Lisa S. BARTON, Brian W. BUDZIK, Jay M. MATTHEWS, John Jeffrey McATEE, Jacyln R. PATTERSON, Joseph E. PERO, Robert SANCHEZ, Matthew Robert SENDER, Lamont Roscoe TERRELL, David J. BEHM, James V. THOMAS
  • Publication number: 20190202784
    Abstract: The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
    Type: Application
    Filed: September 20, 2017
    Publication date: July 4, 2019
    Inventors: Edward J. BRNARDIC, Carl A. BROOKS, Brian W. BUDZIK, Brian Griffin LAWHORN, Jay M. MATTHEWS, John Jeffrey McATEE, Joseh E. PERO, David J. BEHM
  • Patent number: 9487507
    Abstract: The present invention relates to spirocarbamate analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: November 8, 2016
    Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
    Inventors: Carl Brooks, Mui Cheung, Hilary Schenck Eidam, Krista B. Goodman, Marlys Hammond, Mark A. Hilfiker, Jaclyn R. Patterson, Patrick Stoy, Guosen Ye
  • Patent number: 9454619
    Abstract: A user interface for a device comprises a plurality of layers. The content for the user interface is associated with one of the plurality of layers.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: September 27, 2016
    Assignee: QUALCOMM Incorporated
    Inventors: Stefan Geoffrey Butlin, Nicholas Holder Clarey, Nicholas Carl Brook
  • Patent number: 9206936
    Abstract: Disclosed herein is a high compression pipe clamp which in one embodiment has an inner housing and an outer housing. The hollow rigid inner housing may have a first end, an outer diameter, and a first strap bracket. The hollow rigid outer housing may have a first end, and inner diameter and a second strap bracket wherein the inner diameter of the outer housing is larger than the outer diameter of the inner housing to fit thereover. A tensioning device such as for example threaded rod is also disclosed, the threaded rod passing through the inner housing and outer housing and a threaded nut engaging the threads on the threaded rod.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: December 8, 2015
    Inventors: Carl Brooks, Larry Mehlenbacher
  • Patent number: 9187464
    Abstract: The present invention relates to spirocarbamate compounds of Formula (I) in which R1, (R2)Y, R3, R4, X and A have the meanings given in the specification. The invention further provides pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and relates to their use of these compounds as TRPV4 antagonists in treating or preventing conditions associated with TRPV4 imbalance.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: November 17, 2015
    Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
    Inventors: Carl Brooks, Mui Cheung, Hilary Schenck Eidam, Krista B. Goodman, Marlys Hammond, Mark A. Hilfiker, Tram H. Hoang, Jaclyn R. Patterson, Patrick Stoy, Guosen Ye
  • Publication number: 20150013816
    Abstract: Disclosed herein is a high compression pipe clamp which in one embodiment has an inner housing and an outer housing. The hollow rigid inner housing may have a first end, an outer diameter, and a first strap bracket. The hollow rigid outer housing may have a first end, and inner diameter and a second strap bracket wherein the inner diameter of the outer housing is larger than the outer diameter of the inner housing to fit thereover. A tensioning device such as for example threaded rod is also disclosed, the threaded rod passing through the inner housing and outer housing and a threaded nut engaging the threads on the threaded rod.
    Type: Application
    Filed: September 16, 2014
    Publication date: January 15, 2015
    Inventors: Carl Brooks, Larry Mehlenbacher
  • Patent number: 8927585
    Abstract: The present invention relates to spirocarbamate analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: January 6, 2015
    Assignee: GlaxoSmithKline Intellectual Property (NO.2) Limited
    Inventors: Carl Brooks, Mui Cheung, Krista B. Goodman, Marlys Hammond
  • Publication number: 20140282624
    Abstract: The present invention is directed to a method, system, and article of manufacture of a processing pipeline with caching at one or more internal stages for altering processing steps, useful for handling responsive inspection and analysis of high energy security images. A set of particular steps useful for data, image, and X-ray analysis are presented. Several nonlinear processing pipeline architectures comprised of particular useful arrangements of processing steps and features are described: an architecture for conducting radiographic image inspections, an architecture for inspecting/analyzing multiple related imaging modalities (such as X-ray digital radiography (DR) and material discrimination (MD)) in a unified manner, and an architecture for reconstructing computed tomography (CT) X-ray images. In addition, graphical user interface (GUI) facets are described which map to pipeline parameters to control the processing steps and arrangements responsively and intuitively.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 18, 2014
    Applicant: Varian Medical Systems, Inc.
    Inventors: Kevin Matthew HOLT, Alan Carl BROOKS, Stephen John HOELZER, Robert C. GEMPERLINE
  • Patent number: 8833399
    Abstract: Disclosed herein is a high compression pipe clamp which in one embodiment has a hollow rigid inner housing and a hollow rigid outer housing. The hollow rigid inner housing may have a first end, an outer diameter, and a first strap bracket. The hollow rigid outer housing may have a first end, and inner diameter and a second strap bracket wherein the inner diameter of the outer housing is larger than the outer diameter of the inner housing to fit thereover. A threaded rod is also disclosed, the threaded rod passing through the inner housing and outer housing and a threaded nut engaging the threads on the threaded rod.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: September 16, 2014
    Inventors: Carl Brooks, Larry Mehlenbacher
  • Publication number: 20140135369
    Abstract: The present invention relates to spirocarbamate analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
    Type: Application
    Filed: June 15, 2012
    Publication date: May 15, 2014
    Applicant: GlaxoSmith Kline,LLC
    Inventors: Carl Brooks, Mui Cheung, Krista B. Goodman, Marlys Hammond
  • Publication number: 20140121206
    Abstract: The present invention relates to spirocarbamate compounds of Formula (I) in which R1, (R2)Y, R3, R4, X and A have the meanings given in the specification. The invention further provides pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and relates to their use of these compounds as TRPV4 antagonists in treating or preventing conditions associated with TRPV4 imbalance.
    Type: Application
    Filed: June 15, 2012
    Publication date: May 1, 2014
    Applicant: GlaxoSmithKliine, LLC
    Inventors: Carl Brooks, Mui Cheung, Hilary Schenck Eidam, Krista B. Goodman, Marlys Hammond, Mark A. Hilfiker, Tram H. Hoang, Jaclyn R. Patterson, Patrick Stoy, Guosen Ye
  • Publication number: 20140113916
    Abstract: The present invention relates to spirocarbamate analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
    Type: Application
    Filed: June 15, 2012
    Publication date: April 24, 2014
    Applicant: GlaxoSmithKLine, LLC
    Inventors: Carl Brooks, Mui Cheung, Hilary Schenck Eidam, Krista B. Goodman, Marlys Hammond, Mark A. Hilfiker, Jaclyn R. Patterson, Patrick Stoy, Guosen Ye