Patents by Inventor Carlo M. Croce

Carlo M. Croce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-16b
    Publication number: 20120058913
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-181b
    Publication number: 20120058911
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD FOR DIAGNOSING ACUTE LYMPHOMIC LEUKEMIA (ALL) USING MIR-125b
    Publication number: 20120058910
    Abstract: Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
    Type: Application
    Filed: October 17, 2011
    Publication date: March 8, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Carlo M. Croce
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-10a
    Publication number: 20120058915
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 15, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-203
    Publication number: 20120058914
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 15, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING let-7g
    Publication number: 20120058912
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD FOR DIAGNOSING ACUTE LYMPHOMIC LEUKEMIA (ALL) USING MIR-146a
    Publication number: 20120046194
    Abstract: Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
    Type: Application
    Filed: October 17, 2011
    Publication date: February 23, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Carlo M. Croce
  • METHOD FOR DIAGNOSING ACUTE LYMPHOMIC LEUKEMIA (ALL) USING MIR-221
    Publication number: 20120046192
    Abstract: Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
    Type: Application
    Filed: October 17, 2011
    Publication date: February 23, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Carlo M. Croce
  • METHOD FOR DIAGNOSING ACUTE LYMPHOMIC LEUKEMIA (ALL) USING MIR-222
    Publication number: 20120046193
    Abstract: Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
    Type: Application
    Filed: October 17, 2011
    Publication date: February 23, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Carlo M. Croce
  • MiR-182-, miR-191, miR-199a-BASED METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE MYELOID LEUKEMIA (AML)
    Publication number: 20120028832
    Abstract: The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML).
    Type: Application
    Filed: October 7, 2011
    Publication date: February 2, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Carlo M. Croce
  • MicroRNAs in Never-Smokers and Related Materials and Methods
    Publication number: 20120027753
    Abstract: The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of lung cancer in never-smokers. The invention also provides methods of identifying anti-lung cancer agents.
    Type: Application
    Filed: February 24, 2010
    Publication date: February 2, 2012
    Applicants: THE OHIO STATE UNIVERSITY, Department of Health and Human Sevices
    Inventors: Carlo M. Croce, Curtis C. Harris, Masahiro Seike, Izumi Horikawa
  • MiR-25-BASED METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE MYELOID LEUKEMIA (AML)
    Publication number: 20120028833
    Abstract: The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML). The invention also provides methods of identifying anti-AML agents.
    Type: Application
    Filed: October 7, 2011
    Publication date: February 2, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Carlo M. Croce
  • MiR-29-BASED METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE MYELOID LEUKEMIA (AML)
    Publication number: 20120028831
    Abstract: The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML). The invention also provides methods of identifying anti-AML agents.
    Type: Application
    Filed: October 7, 2011
    Publication date: February 2, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Carlo M. Croce
  • Methods for Identifying Fragile Histidine Triad (FHIT) Interaction and Uses Thereof
    Publication number: 20120010092
    Abstract: Provided herein are methods and compositions for the diagnosis, prognosis and treatment of a cancer associated disorder using the Fhit gene.
    Type: Application
    Filed: October 27, 2008
    Publication date: January 12, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Francesco Trapasso
  • Method of diagnosing poor survival prognosis colon cancer using microRNA-21
    Patent number: 8084199
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: December 27, 2011
    Assignees: The Ohio State University Research Foundation, The United States of America as represented by the Department of Health and Human Services, National Institutes of Health, Office of Technology Transfer
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • Tc11 as a Transcriptional Regulator
    Publication number: 20110311555
    Abstract: Methods and compositions for the diagnosis, prognosis and/or treatment of B cell chronic lymphocytic leukemia associated diseases are disclosed.
    Type: Application
    Filed: November 19, 2009
    Publication date: December 22, 2011
    Applicant: THE OHIO STATE UNIVERSITY
    Inventors: Carlo M. Croce, Yuri Pekarsky
  • Leukemia diagnostic methods
    Patent number: 8071292
    Abstract: The present invention provides methods and compositions for the diagnosis, prognosis and treatment of chronic lymphocytic leukemia (CLL). The invention also provides methods of identifying anti-CLL agents.
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: December 6, 2011
    Assignee: The Ohio State University Research Foundation
    Inventor: Carlo M. Croce
  • MICRORNA FINGERPRINTS DURING HUMAN MEGAKARYOCYTOPOIESIS
    Publication number: 20110287970
    Abstract: The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of cancer and myeloproliferative disorders. The invention also provides methods of identifying anti-cancer agents.
    Type: Application
    Filed: June 27, 2011
    Publication date: November 24, 2011
    Inventors: Carlo M. Croce, Ramiro Garzon, George A. Calin
  • MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Ovarian Cancer Using a Real-Time PCR Platform
    Publication number: 20110275534
    Abstract: Methods and compositions for the diagnosis, prognosis and/or treatment of ovarian cancer are disclosed.
    Type: Application
    Filed: March 25, 2009
    Publication date: November 10, 2011
    Applicant: THE OHIO STATE UNIVERSITY
    Inventors: David E. Cohn, Kimberly Resnick, Hansjuerg Alder, Carlo M. Croce
  • Oncogenic ALL-1 fusion proteins for targeting Drosha-mediated microRNA processing
    Patent number: 8053186
    Abstract: Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: November 8, 2011
    Assignee: The Ohio State University Research Foundation
    Inventor: Carlo M. Croce