Abstract: The present invention relates to growth hormone conjugates comprising a bile acid residue, said conjugation may occur through wt or mutant amino acid residues. The growth hormone polypeptide may be wt human growth hormone or a growth hormone variant.

Abstract: A method for detecting the surface character of objects in road traffic or of persons, especially pedestrians, vehicles, obstacles and the like, in which signals are emitted from a vehicle that are reflected by a person or an object, and in which the reflected signals are received and evaluated in the vehicle, wherein the emitted signals are transmit pulses whose echo pulses are received, and based on the signal characteristics of the echo pulses, the surface character is inferred, and from that, it is inferred whether a person or an object is positioned in front of the vehicle.

Abstract: The present invention relates to modified therapeutic proteins, such as e.g. coagula-tion factors. In particular, the present invention relates to conjugated Factor VIII molecules such as e.g. FVII, FVIII, or FIX comprising a hydrophobic side group.

Abstract: The present invention relates to conjugated Factor VIII variants. The present invention in particular relates to conjugated FVIII variants comprising different polymeric groups as well as use thereof.

Abstract: The invention relates to growth hormone compounds with a protracted profile. The effect is obtained by linking an albumin binding residue via a hydrophilic spacer to growth hormone variants. Further described are methods of preparing and using such compounds. These growth hormone compounds are based on there altered profile considered particular useful in therapy.

Abstract: The present invention relates to polypeptide compound optimized for subcutaneous administration, exemplified by growth hormone conjugates having a linker providing non-covalent binding to albumin.

Abstract: The invention described herein relates to novel molecules and polypeptides comprising at least one amino acid sequence having significant identity with (homology to) human Factor VIII or biologically active portion(s) thereof, related molecules (such as nucleic acids encoding such polypeptides), compositions (such as pharmaceutical formulations) comprising such polypeptides, and methods of making and using such polypeptides.

Abstract: A rubber continuous annular baler press belt is made of at least one of rubber and rubber-like materials. The press belt includes an embedded core of a reinforcing fabric and has at least two individual superimposed fabric layers (6, 7, 8). The ends of each fabric layer mutually abut and do not overlap each other at the abutment location. The abutment locations (11, 13, 15) are arranged over the periphery of the press belt so as to be offset from each other.

Abstract: In order to enhance a safety system, in particular an accident avoidance system for a means of transportation, in particular a motor vehicle, having at least one steering system and at least one brake system in such a way that an avoidance maneuver initiated by the operator of the means of transportation when approaching an obstacle is supported with respect to both the device and the method, thus preventing an accident through collision, the evaluation unit determines at least one driving variation, in particular at least one avoidance trajectory and/or at least one automatic emergency braking action from the data and information and when or after the operator of the means of transportation initiates a driving maneuver, in particular an avoidance maneuver or an emergency braking maneuver, the safety system, in particular the evaluation unit specifies, supports and/or suggests this driving maneuver in an optimized form, in particular in the form of an optimal avoidance trajectory or in the form of an automati

Abstract: The invention concerns a preparation comprising a plurality of Factor VII polypeptides or Factor VII-related polypeptides, wherein the polypeptides comprise asparagine-linked and/or serine-linked oligosaccharide chains, and wherein at least one oligosaccharide group is covalently attached to at least one polymeric group.

Abstract: The invention relates to conjugated proteins, in particular but not exclusively, blood coagulation factors, to processes for preparing said conjugates, to pharmaceutical compositions comprising said conjugates and to the use of the conjugates in therapy, in particular but not exclusively, for the treatment of diseases alleviated by blood coagulation factors such as the prophylactic treatment of hemophilia.

Abstract: The invention relates to an activation system (1) for a robotic vehicle (2), comprising at least one external camera (8) configured for generating image data of a work area (3) and of at least one robotic vehicle (2), and comprising at least one external logic unit (10) configured for determining the position of the at least one robotic vehicle (2) based on the image data generated by the camera (8), and comprising an external transmission unit (15, 20) configured for transmitting driving instructions, and comprising a receiving unit (16, 21) configured for receiving the driving instructions, and further comprising a controller (18) for activating drive means of at least one robotic vehicle (2) based on the driving instructions.

Abstract: Method of conjugating glycoproteins by means of chemical modification is provided as well as new modified glycoproteins.

Abstract: This invention relates to novel compounds, methods for selective chemical conjugation of protractor molecules and the use thereof for diagnostic and/or therapeutic purposes.

Abstract: The invention provides synthesis and application of new structural well defined branched polymers as protraction agents for peptide and protein.

Abstract: The invention concerns a preparation comprising a plurality of Factor VII polypeptides or Factor VII-related polypeptides, wherein the polypeptides comprise asparagine-linked and/or serine-linked oligosaccharide chains, and wherein at least one oligosaccharide group is covalently attached to at least one polymeric group.

Abstract: A method for detecting the surface character of objects in road traffic or of persons, especially pedestrians, vehicles, obstacles and the like, in which signals are emitted from a vehicle that are reflected by a person or an object, and in which the reflected signals are received and evaluated in the vehicle, wherein the emitted signals are transmit pulses whose echo pulses are received, and based on the signal characteristics of the echo pulses, the surface character is inferred, and from that, it is inferred whether a person or an object is positioned in front of the vehicle.

Abstract: A novel class of compounds, which act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor the compounds may be suitable for the treatment and/or prevention of any glucagon-mediated conditions and diseases such as hyperglycemia, Type 1 diabetes, Type 2 diabetes and obesity.

Abstract: Insulin conjugated with structurally well defined, bifurcated and trifurcated polymers can be use by pulmonary delivery for systemic absorption through the lungs to reduce or eliminate the need for administering other insulins by injection.

Abstract: The invention provides compounds of formula (I) for use as GLP-1 receptor agonists.