Patents by Inventor Ce Shi

Ce Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220064710
    Abstract: The present disclosure includes compounds, compositions, and methods for nucleic acid amplification reactions. In particular, the present disclosure provides compounds, compositions, and methods for viability PCR (vPCR) applications, in which the compounds that selectively bind to nucleic acids from non-viable cells.
    Type: Application
    Filed: September 1, 2021
    Publication date: March 3, 2022
    Inventors: Ce SHI, Nathan FEIRER, Michael SCURRIA, Subhanjan MONDAL, Said GOUELI, Thomas KIRKLAND, James J. CALI, Poncho MEISENHEIMER
  • Patent number: 11261478
    Abstract: Provided herein are inhibitor-resistant luciferase mutants, and methods of use thereof. In particular, luciferase mutants are provided that are thermal stable and exhibit improved stability in the presence of luciferin break-down products, such as dehydroluciferin. Further provided are assay systems comprising inhibitor-resistant luciferase mutants and amino acid sequences of the inhibitor-resistant luciferase mutants.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: March 1, 2022
    Assignee: Promega Corporation
    Inventors: Ce Shi, Thomas Kirkland, Poncho Meisenheimer, Lance P. Encell, Mary Hall
  • Patent number: 11136615
    Abstract: Disclosed herein are compositions and methods for stabilizing a benzothiazole luciferin analog such as D-luciferin and 6-amino-D-luciferin. The compositions may include the benzothiazole luciferin analog, a thionucleobase compound of formula (I), and a liquid medium, in which the thionucleobase is present in an amount effective to stabilize the luminogenic composition against decomposition. The methods provided herein may stabilize the benzothiazole luciferin analog against decomposition by contacting the benzothiazole luciferin analog with an effective amount of the thionucleobase compound in the presence of a liquid medium. Also provided herein is a kit containing the composition.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: October 5, 2021
    Assignee: PROMEGA CORPORATION
    Inventors: Ce Shi, Mary P. Hall, Thomas A. Kirkland, Lance P. Encell, Poncho Meisenheimer, Wenhui Zhou
  • Patent number: 10977533
    Abstract: A vehicle windshield with a two-dimensional code includes a first glass, a second glass and an intermediate film provided between the first glass and the second glass. The first glass includes a first surface facing the exterior of a vehicle and a second surface adhered to the intermediate film, while the second glass includes a third surface adhered to the intermediate film and a fourth surface facing the interior of the vehicle. Black enamel paint is printed on the second surface and/or the fourth surface. The second surface or the fourth surface is provided with a two-dimensional code printed with enamel paint at a position corresponding to the black enamel paint. The two-dimensional code contains unique information of the glass and/or the vehicle.
    Type: Grant
    Filed: December 25, 2018
    Date of Patent: April 13, 2021
    Assignee: SAINT-GOBAIN GLASS FRANCE
    Inventors: Ce Shi, Huanhuan Wu
  • Publication number: 20210088783
    Abstract: A laminated glass for implementing HUD function, the laminated glass including an outer glass layer; an inner glass layer; a PVB film located between the outer glass layer and the inner glass layer; wherein the PVB film is of a uniform thickness, the laminated glass further includes a reflection film.
    Type: Application
    Filed: March 27, 2018
    Publication date: March 25, 2021
    Inventors: Ce SHI, Yunxin GU, Chong ZHOU
  • Publication number: 20210080470
    Abstract: Provided herein are systems and methods for characterizing target/ligand engagement. In particular, luciferase-labeled polypeptide targets are used to detect or quantify target/ligand engagement (e.g., within a cell or cell lysate).
    Type: Application
    Filed: November 25, 2020
    Publication date: March 18, 2021
    Inventors: Melanie Dart, Lance P. Encell, Thomas Kirkland, Thomas Machleidt, Matthew Robers, Brock F. Binkowski, Keith Wood, Ce Shi
  • Patent number: 10928400
    Abstract: Provided herein are systems and methods for characterizing target/ligand engagement. In particular, luciferase-labeled polypeptide targets are used to detect or quantify target/ligand engagement (e.g., within a cell or cell lysate).
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: February 23, 2021
    Assignee: Promega Corporation
    Inventors: Melanie Dart, Lance P. Encell, Thomas Kirkland, Thomas Machleidt, Matthew Robers, Brock F. Binkowski, Keith Wood, Ce Shi
  • Publication number: 20210040058
    Abstract: Provided herein are surfactant compounds that can be used to aid in preparation of protein samples for analysis, for example by mass spectrometry.
    Type: Application
    Filed: August 6, 2020
    Publication date: February 11, 2021
    Inventors: Joel Walker, Sergei Saveliev, Zhiyang Zeng, Robert Kargbo, Hui Wang, Sergiy Levin, Valerie Ressler, Jun Zhang, Ce Shi, Harry Tetsuo Uyeda, Jean Osterman, Min Zhou, Prabin Rai, Wenhui Zhou
  • Patent number: 10913972
    Abstract: Described are luciferin analogues, methods for making the analogues, kits including the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: February 9, 2021
    Assignee: Promega Corporation
    Inventors: Lance P. Encell, Mary P. Hall, Michael Killoran, Thomas A. Kirkland, Poncho Meisenheimer, Ce Shi
  • Publication number: 20200354265
    Abstract: A thermal insulating glass includes a glass substrate and a thermal insulating layer. The thermal insulating layer includes composite tungsten oxide and a binder. The composite tungsten oxide is represented by formula (1): MxWO3?yAy (1), where M is an alkali metal element or an alkaline earth metal element, W is tungsten, O is oxygen, A is a halogen element, and 0?x?1 and 0?y?0.5. And the binder includes one or more of the following components: silicon dioxide, titanium dioxide, and aluminium oxide. The thermal insulating glass can prevent the occurrence of obscuration. The thermal insulating has infrared reflectivity, high strength and good wear resistance, and can effectively resist high temperature and strong oxidation environment.
    Type: Application
    Filed: December 25, 2018
    Publication date: November 12, 2020
    Inventors: Yunxin GU, Ce SHI, Chong ZHOU
  • Publication number: 20200257948
    Abstract: A vehicle windshield with a two-dimensional code includes a first glass, a second glass and an intermediate film provided between the first glass and the second glass. The first glass includes a first surface facing the exterior of a vehicle and a second surface adhered to the intermediate film, while the second glass includes a third surface adhered to the intermediate film and a fourth surface facing the interior of the vehicle. Black enamel paint is printed on the second surface and/or the fourth surface. The second surface or the fourth surface is provided with a two-dimensional code printed with enamel paint at a position corresponding to the black enamel paint. The two-dimensional code contains unique information of the glass and/or the vehicle.
    Type: Application
    Filed: December 25, 2018
    Publication date: August 13, 2020
    Inventors: Ce SHI, Huanhuan WU
  • Publication number: 20200246895
    Abstract: A resistive soldering system, includes a first electrode; a second electrode; a support cylinder; a resistive soldering joint which is adapted to raise or lower the first electrode, the second electrode and the support cylinder; and a power supply unit which is connected with the first and second electrodes and adapted to supply power and a heating current to the first and second electrodes.
    Type: Application
    Filed: April 22, 2020
    Publication date: August 6, 2020
    Inventors: Ce SHI, Shengwen YU, Huanhuan WU
  • Publication number: 20200174012
    Abstract: Provided herein are systems and methods for characterizing target/ligand engagement. In particular, luciferase-labeled polypeptide targets are used to detect or quantify target/ligand engagement (e.g., within a cell or cell lysate).
    Type: Application
    Filed: February 11, 2020
    Publication date: June 4, 2020
    Inventors: Melanie Dart, Lance P. Encell, Thomas Kirkland, Thomas Machleidt, Matthew Robers, Brock F. Binkowski, Keith Wood, Ce Shi
  • Patent number: 10668549
    Abstract: A resistive soldering method, assembly of antenna and glass, and resistive soldering system are provided. The method includes providing glass and an antenna component including a base structure and a cylindrical structure having a hole on a front surface of the base structure; forming solder on a surface to be soldered of the glass or a surface to be soldered of the base structure; resistive soldering the surfaces to be soldered of the glass and the base structure to melt the solder, wherein during the resistive soldering process, first and second electrodes are used to apply pressure and heating current to edge portion on the front surface of the base structure, and a support cylinder is inserted into the hole and applies to the antenna component a pressure for attaching the antenna component to the glass.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: June 2, 2020
    Assignee: SAINT-GOBAIN GLASS FRANCE
    Inventors: Ce Shi, Shengwen Yu, Huanhuan Wu
  • Patent number: 10654204
    Abstract: A method for forming an encapsulation assembly, and a vehicle window are provided. The method includes: providing a reinforcement component; forming a primer layer covering a surface of the reinforcement component; performing a heating treatment on the reinforcement component after the primer layer is formed, to elevate a temperature of the reinforcement component; and injecting a gasket material in a mold onto the surface of the reinforcement component with elevated temperature to form a gasket. The vehicle window includes a glass; and the encapsulation assembly formed by the above method. The gasket may bind with the primer layer more closely. That is to say, binding force between the reinforcement component and the gasket may be increased. In this way, the gasket may not easily detach from the reinforcement component.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: May 19, 2020
    Assignee: SAINT-GOBAIN GLASS FRANCE
    Inventors: Yang Sun, Ce Shi, Xiaohui Guo
  • Publication number: 20200071682
    Abstract: Provided herein are enhanced luciferase enzymes for use with thermostable luciferin analogs for bioluminescent assays. In particular, the present disclosure provides compositions, assays, and methods for performing a bioluminescent assay using enhanced, high-activity luciferase enzymes compatible with thermostable luciferins, such as 5,5-disubstituted luciferin analogs.
    Type: Application
    Filed: June 5, 2019
    Publication date: March 5, 2020
    Inventors: Michael Killoran, Ce Shi, Mary Hall, Lance P. Encell, Thomas Kirkland
  • Patent number: 10571471
    Abstract: Provided herein are systems and methods for characterizing target/ligand engagement. In particular, luciferase-labeled polypeptide targets are used to detect or quantify target/ligand engagement (e.g., within a cell or cell lysate).
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: February 25, 2020
    Assignee: Promega Corporation
    Inventors: Melanie Dart, Lance P. Encell, Thomas Kirkland, Thomas Machleidt, Matthew Robers, Brock F. Binkowski, Keith Wood, Ce Shi
  • Publication number: 20190338340
    Abstract: Described are luciferin analogues, methods for making the analogues, kits including the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.
    Type: Application
    Filed: July 19, 2019
    Publication date: November 7, 2019
    Inventors: Lance P. Encell, Mary P. Hall, Michael Killoran, Thomas A. Kirkland, Poncho Meisenheimer, Ce Shi
  • Publication number: 20190309342
    Abstract: Provided herein are inhibitor-resistant luciferase mutants, and methods of use thereof. In particular, luciferase mutants are provided that are thermal stable and exhibit improved stability in the presence of luciferin break-down products, such as dehydroluciferin. Further provided are assay systems comprising inhibitor-resistant luciferase mutants and amino acid sequences of the inhibitor-resistant luciferase mutants.
    Type: Application
    Filed: October 13, 2017
    Publication date: October 10, 2019
    Inventors: Ce Shi, Thomas Kirkland, Poncho Meisenheimer, Lance P. Encell, Mary Hall
  • Publication number: 20190283162
    Abstract: A resistive soldering method, assembly of antenna and glass, and resistive soldering system are provided. The method includes providing glass and an antenna component including a base structure and a cylindrical structure having a hole on a front surface of the base structure; forming solder on a surface to be soldered of the glass or a surface to be soldered of the base structure; resistive soldering the surfaces to be soldered of the glass and the base structure to melt the solder, wherein during the resistive soldering process, first and second electrodes are used to apply pressure and heating current to edge portion on the front surface of the base structure, and a support cylinder is inserted into the hole and applies to the antenna component a pressure for attaching the antenna component to the glass.
    Type: Application
    Filed: May 4, 2017
    Publication date: September 19, 2019
    Inventors: Ce SHI, Shengwen YU, Huanhuan WU