Patents by Inventor Chang Xu

Chang Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7001908
    Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: February 21, 2006
    Assignees: Avera Pharmaceuticals, Inc., Eli Lilly and Company
    Inventors: Alexander Glenn Godfrey, Daniel Timothy Kohlman, John Cunningham O'Toole, Yao-Chang Xu, Tony Yantao Zhang
  • Publication number: 20060026628
    Abstract: A method and apparatus inserts virtual advertisements or other virtual contents into a sequence of frames of a video presentation by performing real-time content-based video frame processing to identify suitable locations in the video for implantation. Such locations correspond to both the temporal segments within the video presentation and the regions within an image frame that are commonly considered to be of lesser relevance to the viewers of the video presentation. This invention presents a method and apparatus that allows a non-intrusive means to incorporate additional virtual content into a video presentation, facilitating an additional channel of communications to enhance greater video interactivity.
    Type: Application
    Filed: July 29, 2005
    Publication date: February 2, 2006
    Inventors: Kong Wah Wan, Chang Xu, Joo Lim, Xin Yu
  • Publication number: 20060009464
    Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
    Type: Application
    Filed: September 13, 2005
    Publication date: January 12, 2006
    Inventors: Alexander Godfrey, Daniel Kohlman, John O'Toole, Yao-Chang Xu, Tony Zhang, Jeffrey McKelvy
  • Publication number: 20050282817
    Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
    Type: Application
    Filed: July 19, 2005
    Publication date: December 22, 2005
    Inventors: Alexander Godfrey, Daniel Kohlman, John O'Toole, Yao-Chang Xu, Tony Zhang
  • Publication number: 20050278605
    Abstract: An encoder system for encoding a signal according to any number of FEC and/or channel codes comprises a shift register, an array of MOD/XOR stages, and a generator matrix stage for controlling the connections between the shift register and the MOD/XOR stages and altering these connections according to a coding format selected by an encoder selection stage. There is also disclosed a decoder system for decoding a signal encoded according to a number of FEC and/or channel codes comprising a decoding stage, and a generator matrix stage for configuring the decoding stage to a decoding code format to be applied an incoming encoded signal. A decoder selection stage is coupled to the generator matrix stage and selects the decoding code format to be used in the decoding process. The decoder selection stage instructs the generator matrix stage to configure the decoding stage according to the selected decoding code format. There is also disclosed a method for encoding and decoding.
    Type: Application
    Filed: May 19, 2005
    Publication date: December 15, 2005
    Inventors: Chang Xu, Masayuki Tomisawa
  • Publication number: 20050238121
    Abstract: A system and method for determining a modulation angle of an information bit in a modulated complex signal comprise, in a first stage, determining the inphase component I and the quadrature component Q of the information bit in the modulated complex signal. A division stage determines an absolute ratio of the quadrature component Q to the inphase component I and a second stage determines from the polarity of the inphase and quadrature components the quadrant in which the modulation angle lies. A third stage determines the arctangent of the absolute ratio x of the quadrature component Q to the inphase component I of the transmitted information bit in the modulated signal. A fourth stage determines the modulation angle from the polarity of the inphase and quadrature components and the arctangent of the absolute ratio of the quadrature component Q to the inphase component I of the transmitted information bit in the modulated signal.
    Type: Application
    Filed: March 24, 2005
    Publication date: October 27, 2005
    Inventors: Chang Xu, Masayuki Tomisawa
  • Publication number: 20050222206
    Abstract: The present invention relates to compounds of formula I: or pharmaceutically acceptable acid addition salts thereof, where; R1 is C1-C6 alkyl, substituted C1-C6 alkyl, C3-C7 cycloalkyl, substituted C3-C7 cycloalkyl, C3-C7 cycloalkyl-C1-C3 alkyl, substituted C3-C7 cycloalkyl-C1-C3 alkyl, phenyl, substituted phenyl, heterocycle, or substituted heterocycle; R2 is hydrogen, C1-C3 alkyl, C3-C6 cycloalkyl-C1-C3 alkyl, or a group of formula II R3 is hydrogen or C1-C3 alkyl; R4 is hydrogen, halo, or C1-C3 alkyl; R5 is hydrogen or C1-C3 alkyl; R6 is hydrogen or C1-C6 alkyl; and n is an integer from 1 to 6 inclusively. The compounds of the present invention are useful for activating 5-HT1F receptors, inhibiting neuronal protein extravasation, and for the treatment or prevention of migraine in a mammal. The present invention also relates to a process for the synthesis of intermediates in the synthesis of compounds of Formula I.
    Type: Application
    Filed: March 27, 2003
    Publication date: October 6, 2005
    Inventors: Michael Cohen, Daniel Kohlman, Sidney Liang, Vincent Mancuso, Yao-Chang Xu, Bai-Ping Ying, DeAnna Zacherl, Deyi Zhang, Frantz Victor
  • Publication number: 20050207276
    Abstract: An egg beater includes a seat, and a stirring net mounted on the seat and including a plurality of primary stirring strips and a plurality of secondary stirring strips. Each of the primary stirring strips has a surface formed with a helical groove. Thus, the air is introduced into the dough rapidly and largely by guide of the helical grooves of the primary stirring strips during rotation of the stirring net, so that the air input introduced into the dough is greatly enhanced, thereby decreasing the stirring time of the egg beater.
    Type: Application
    Filed: March 22, 2004
    Publication date: September 22, 2005
    Inventors: Shun-Xing Xu, Yu-Chang Xu, Yu-Ting Xu
  • Patent number: 6946579
    Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: September 20, 2005
    Assignee: Eli Lilly and Company
    Inventors: Alexander Glenn Godfrey, Daniel Timothy Kohlman, John Cunningham O'Toole, Yao-Chang Xu, Tony Yantao Zhang
  • Publication number: 20050190827
    Abstract: A modulation/demodulation apparatus for the encoding and decoding of data, for example in a Bluetooth/WLAN/PHS multi-mode system based on software defined radio comprises an encoding system to encode data according to a plurality of modulation schemes and a decoding system to decode according to the plurality of modulation schemes the encoded data from the encoding system. The encoding system comprises a number of encoding look-up tables which include encoding data for encoding data according to the plurality of modulation schemes, the encoding data for a plurality of the modulation schemes being identical. Similarly, the decoding system comprises a number of decoding look-up tables for decoding the encoded data received from the encoding system. The decoding look-up tables comprise decoding data for decoding data according to the plurality of modulation schemes, the decoding data for a plurality of the modulation schemes being identical. Also disclosed is a method for encoding/decoding data.
    Type: Application
    Filed: February 25, 2005
    Publication date: September 1, 2005
    Inventors: Chang Xu, Masayuki Tomisawa
  • Patent number: 6881733
    Abstract: The present invention provides serotonergic benzofurans of Formula (I): where A, R, R1, R2, R3, and R4 are as described in the specification.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: April 19, 2005
    Assignee: Eli Lilly and Company
    Inventors: Karin Briner, Joseph Paul Burkhart, Timothy Paul Burkholder, Brian Eugene Cunningham, Matthew Joseph Fisher, William Harlan Gritton, Cynthia Darshini Jesudason, Shawn Christopher Miller, Jeffrey Thomas Mullaney, Matthew Robert Reinhard, Roger Ryan Rothhaar, Freddie Craig Stevens, Leonard Larry Winneroski, Yanping Xu, Yao-Chang Xu
  • Patent number: 6828332
    Abstract: The present invention provides compounds of formula (I) and a method of inhibiting the reuptake of serotonin and antagonizing the serotonin receptor which comprises administering to a subject in need of such treatment an effective amount of a compound of formula (I).
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: December 7, 2004
    Assignee: Eli Lilly and Company
    Inventors: Daniel Timothy Kohlman, Sidney Xi Liang, Yao-Chang Xu
  • Publication number: 20040049083
    Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
    Type: Application
    Filed: July 2, 2003
    Publication date: March 11, 2004
    Inventors: Alexander Glenn Godfrey, Daniel Timothy Kohlman, John Cunningham O'Toole, Yao-Chang Xu, Tony Yantao Zhang
  • Publication number: 20040044009
    Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
    Type: Application
    Filed: April 16, 2003
    Publication date: March 4, 2004
    Inventors: Alexander Glenn Godfrey, Daniel Timothy Kohlman, John Cunningham O'Toole, Yao-Chang Xu, Tony Yantao Zhang
  • Patent number: 6664274
    Abstract: The present invention provides compounds of formula I and a method of inhibiting the reuptake of serotonin, antagonizing the 5-HT1A receptor and antagonizing the 5-HT2A receptor which comprises administering to a subject in need of such treatment an effective amount of a compound of formula I.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: December 16, 2003
    Assignee: Eli Lilly and Company
    Inventors: Sidney Xi Liang, Yao-Chang Xu
  • Patent number: 6660859
    Abstract: Described herein is a series of aryl piperazine compounds of the formula: wherein Ar′ is a mono or bicyclic aryl or heteroaryl radical substituted with one to three substituents selected from the group consisting of hydrogen, (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)alkylthio, (C2-C6)alkenyl, (C2-C6)alkynyl, (C1-C6)alkylhalo, (C3-C5)cycloalkyl, (C3-C8)cycloalkenyl or halo; R1 is hydrogen, (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)alkylthio; R2 is phenyl, naphthyl or (C3-C12)cycloalkyl substituted with one or two substituents selected from the group consisting of hydrogen (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)alkylthio, (C2-C6)alkenyl, (C2-C6)alkynyl, (C1-C6)alkylhalo, (C3-C8)cycloalkyl, (C3-C8)cycloalkenyl or halo; R3 is selected from the group consisting of hydrogen (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)alkylthio, (C2-C6)alkenyl, (C2-C6)alkynyl, (C1-C6)alkylhalo, (C3-C5)cycloalkyl, (C3-C8)cycloalkenyl or halo; X is —(C═O)—, —CHOH— or —CH2—; or a pharmac
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: December 9, 2003
    Assignee: Eli Lilly and Company
    Inventors: Daniel Timothy Kohlman, Yao-Chang Xu
  • Patent number: 6645967
    Abstract: Described herein is a method for potentiating the action of a serotonin reuptake inhibitor in increasing the availability of serotonin, norepinephrin and dopamine in the brain, by administering to a patient an effective amount of a compound of the formula wherein Ar′ is a mono or bicyclic aryl or heteroaryl radical substituted with one to three substituents selected from the group consisting of hydrogen, (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)alkylthio, (C2-C6)alkenyl, (C2-C6)alkynyl, (C1-C6)alkylhalo, (C3-C8)cycloalkyl, (C3-C8)cycloalkenyl or halo; R1 is hydrogen, (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)alkylthio; R2 is phenyl, naphthyl or (C3-C12)cycloalkyl substituted with one or two substituents selected from the group consisting of hydrogen (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)alkylthio, (C2-C6)alkenyl, (C2-C6)alkynyl, (C1-C6)alkylhalo, (C3-C8)cycloalkyl, (C3-C8)cycloalkenyl or halo; R3 is selected from the group consisting of hydrogen (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)alkylthio, (C
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: November 11, 2003
    Assignee: Eli Lilly and Company
    Inventors: Daniel Timothy Kohlman, Yao-Chang Xu
  • Patent number: 6608079
    Abstract: The present invention relates to a compound of formula (I), or a pharmaceutical acid addition salt thereof, which are useful for activating 5-HT1F receptors and inhibiting neuronal protein extravasation in a mammal.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: August 19, 2003
    Assignee: Eli Lilly and Company
    Inventors: John Mehnert Schaus, Yao-Chang Xu
  • Publication number: 20030088424
    Abstract: A method is provided of restricted substance management and recycling in a manufacturing environment. The method includes the steps of inputting restricted substances and recycle content data of parts supplied by a supplier for a vehicle into a computer system of a vehicle manufacturer. The method also includes the steps of reviewing the inputted data and determining parts with banned or recycled content or substances over predetermined thresholds. The method further includes the steps of reporting the determined parts to the supplier and vehicle manufacture.
    Type: Application
    Filed: November 5, 2001
    Publication date: May 8, 2003
    Inventors: Bernd Gottselig, Bing Chang Xu, Frank Kovacic, Holly Zhang, John Lincoln Nelson, Pratapa Srikiran, Richard J. Gilbert
  • Patent number: D511071
    Type: Grant
    Filed: March 22, 2004
    Date of Patent: November 1, 2005
    Inventors: Shun-Xing Xu, Yu-Chang Xu, Yu-Ting Xu