Patents by Inventor Changjun Yu

Changjun Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12497293
    Abstract: Disclosed is a system and method for preparing hydrogen chloride and ammonia gas by using ammonium chloride. The system includes a decomposition reactor and at least one regeneration reactor, or includes a reactor that may serve as the decomposition reactor and the regeneration reactor; ammonium chloride in particle form is continuously added to the decomposition reactor via a solid particle feed apparatus, and reacts with molten-state ammonium hydrogen sulfate to generate hydrogen chloride gas and an intermediate material; the intermediate material is discharged to the regeneration reactor, and heated therein to decompose into ammonium hydrogen sulfate and ammonia gas; and the ammonium hydrogen sulfate is returned to the decomposition reactor for recycling.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: December 16, 2025
    Assignee: YUANCHU TECHNOLOGY (BEIJING) CO., LTD.
    Inventors: Changjun Yu, Qi Wang
  • Publication number: 20250332114
    Abstract: The invention provides compositions comprising a single protein having one or more molecules of a pharmaceutical agent tightly bound therein. The compositions are useful to decrease the toxicity and/or to widen the therapeutic window of the pharmaceutical agent. The invention also provides methods for preparing such a composition.
    Type: Application
    Filed: April 29, 2025
    Publication date: October 30, 2025
    Applicant: Sunstate Biosciences, LLC
    Inventor: Changjun Yu
  • Patent number: 12398044
    Abstract: Disclosed is a method for preparing ammonia gas through a reaction between an ammonium salt and a silicate. An aqueous solution of the ammonium salt in the form of atomized droplets is contacted with a silicate at a high temperature for a reaction to generate ammonia gas and a solid substance. The silicate can be solid particles, and forms a bed. The generated ammonia gas is collected, the solid substance is extracted, part of the same solid substance is mixed with a fresh silicate solid particle, and the mixture continuously reacts with the atomized droplets of the aqueous solution of the ammonium salt.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: August 26, 2025
    Assignee: YUANCHU TECHNOLOGY (BEIJING) CO., LTD.
    Inventors: Changjun Yu, Qi Wang
  • Patent number: 12391562
    Abstract: Disclosed are a preparation device and a preparation method of ammonia gas. The preparation device, prepares ammonia gas by reacting ammonium chloride with a particulate inorganic salt, includes one fluidized bed reactor with at least two fluidization chambers, in which one is a preheating chamber configured to preheat the particulate inorganic salt, and the other is a reaction chamber inside provided with at least one atomizing nozzle, the particulate inorganic salt forming a fluidized bed layer and reacting with an aqueous solution of ammonium chloride in the reaction chamber to generate the ammonia gas. The particulate inorganic salt can be sequentially flowed through a plurality of preheating chambers and reaction chambers under an impetus of a density difference of the particulate bed layers, finally achieving the required conversion rate.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: August 19, 2025
    Assignee: YUANCHU TECHNOLOGY (BEIJING) CO., LTD.
    Inventors: Qi Wang, Changjun Yu
  • Patent number: 12357679
    Abstract: A non-covalent complex of an albumin molecule and a hydrophobic ligand, compositions containing the same, and methods of use thereof are provided. The present complex may find use in delivering the hydrophobic ligand to microorganisms that have albumin-binding outer surfaces, such as a cell wall.
    Type: Grant
    Filed: May 4, 2023
    Date of Patent: July 15, 2025
    Assignee: Spectral Platforms, Inc.
    Inventors: Ravi Verma, Changjun Yu
  • Patent number: 12311058
    Abstract: The invention provides compositions comprising a single protein having one or more molecules of a pharmaceutical agent tightly bound therein. The compositions are useful to decrease the toxicity and/or to widen the therapeutic window of the pharmaceutical agent. The invention also provides methods for preparing such a composition.
    Type: Grant
    Filed: March 30, 2023
    Date of Patent: May 27, 2025
    Assignee: SUNSTATE BIOSCIENCES, LLC
    Inventor: Changjun Yu
  • Publication number: 20240287140
    Abstract: The invention provides compositions comprising a single protein having one or more biopolymers or modified biopolymers for therapeutics and diagnostics tightly bound therein. The compositions are useful to enhance efficacy and water solution of biopolymers, decrease their toxicity and/or to widen therapeutic window of the biopolymers. The invention also provides methods for preparing such compositions.
    Type: Application
    Filed: January 17, 2024
    Publication date: August 29, 2024
    Applicant: Sunstate Biosciences, LLC
    Inventor: Changjun Yu
  • Patent number: 12011702
    Abstract: Provided is a system and a method for preparing ultrafine silica by leaching silicate ore using hydrogen chloride gas, comprising an ore raw material feeding device, an ejector, a stirring tank and a liquid-solid separation device. A circulated material outlet of a stirred tank is connected with a liquid inlet of an ejector through a circulation pipe; a liquid outlet of the ejector is connected with a circulated material inlet of the stirred tank; a material outlet of a raw ore feeding apparatus is connected with the circulation pipe; and the circulated material outlet of the stirred tank is connected with a solid-liquid separation apparatus. Based on the system and method in the present disclosure, an industrially feasible solution for preparing silica by continuously leaching a silicate ore is provided. The dissolution efficiency of ores and the utilization of hydrochloric acid are greatly increased.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: June 18, 2024
    Assignee: YUANCHU TECHNOLOGY (BEIJING) CO., LTD.
    Inventors: Changjun Yu, Qi Wang
  • Publication number: 20240075107
    Abstract: A non-covalent complex of an albumin molecule and a hydrophobic ligand, compositions containing the same, and methods of use thereof are provided. The present complex may find use in delivering the hydrophobic ligand to microorganisms that have albumin-binding outer surfaces, such as a cell wall.
    Type: Application
    Filed: May 4, 2023
    Publication date: March 7, 2024
    Inventors: Ravi Verma, Changjun Yu
  • Publication number: 20240016948
    Abstract: The invention provides compositions comprising a single protein having one or more molecules of a pharmaceutical agent tightly bound therein. The compositions are useful to decrease the toxicity and/or to widen the therapeutic window of the pharmaceutical agent. The invention also provides methods for preparing such a composition.
    Type: Application
    Filed: March 30, 2023
    Publication date: January 18, 2024
    Applicant: Sunstate Biosciences, LLC
    Inventor: Changjun Yu
  • Patent number: 11696957
    Abstract: The invention provides compositions comprising a single protein having one or more molecules of a pharmaceutical agent tightly bound therein. The compositions are useful to decrease the toxicity and/or to widen the therapeutic window of the pharmaceutical agent. The invention also provides methods for preparing such a composition.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: July 11, 2023
    Assignee: Sunstate Biosciences, LLC
    Inventor: Changjun Yu
  • Publication number: 20220234905
    Abstract: Disclosed is a method for preparing ammonia gas through a reaction between an ammonium salt and a silicate. An aqueous solution of the ammonium salt in the form of atomized droplets is contacted with a silicate at a high temperature for a reaction to generate ammonia gas and a solid substance. The silicate can be solid particles, and forms a bed. The generated ammonia gas is collected, the solid substance is extracted, part of the same solid substance is mixed with a fresh silicate solid particle, and the mixture continuously reacts with the atomized droplets of the aqueous solution of the ammonium salt.
    Type: Application
    Filed: August 12, 2019
    Publication date: July 28, 2022
    Inventors: Changjun Yu, Qi Wang
  • Publication number: 20220204352
    Abstract: Provided is a system and a method for preparing ultrafine silica by leaching silicate ore using hydrogen chloride gas, comprising an ore raw material feeding device, an ejector, a stirring tank and a liquid-solid separation device. A circulated material outlet of a stirred tank is connected with a liquid inlet of an ejector through a circulation pipe; a liquid outlet of the ejector is connected with a circulated material inlet of the stirred tank; a material outlet of a raw ore feeding apparatus is connected with the circulation pipe; and the circulated material outlet of the stirred tank is connected with a solid-liquid separation apparatus. Based on the system and method in the present disclosure, an industrially feasible solution for preparing silica by continuously leaching a silicate ore is provided. The dissolution efficiency of ores and the utilization of hydrochloric acid are greatly increased.
    Type: Application
    Filed: August 12, 2019
    Publication date: June 30, 2022
    Inventors: Changjun Yu, Qi Wang
  • Publication number: 20220113256
    Abstract: Methods and systems for Resonant Raman spectroscopy are provided. Methods according to certain embodiments include irradiating a sample with a monochromatic light source at a first irradiation intensity and a second irradiation intensity, determining the intensity of one or more of the Resonant Raman scattering and fluorescence scattering at the first irradiation intensity and second irradiation intensity, calculating a rate of change of one or more of the intensity of Resonant Raman scattering and fluorescence in response to the change in irradiation intensity from the first irradiation intensity to the second irradiation intensity and comparing one or more of the rate of change in the intensity of Resonant Raman scattering and the rate of change in the intensity of fluorescence scattering with the rate of change in the irradiation intensity by the monochromatic light source to determine the Resonant Raman response of the sample.
    Type: Application
    Filed: July 21, 2021
    Publication date: April 14, 2022
    Inventors: Ravi Verma, Changjun Yu
  • Publication number: 20220098048
    Abstract: Disclosed are a preparation device and a preparation method of ammonia gas. The preparation device, prepares ammonia gas by reacting ammonium chloride with a particulate inorganic salt, includes one fluidized bed reactor with at least two fluidization chambers, in which one is a preheating chamber configured to preheat the particulate inorganic salt, and the other is a reaction chamber inside provided with at least one atomizing nozzle, the particulate inorganic salt forming a fluidized bed layer and reacting with an aqueous solution of ammonium chloride in the reaction chamber to generate the ammonia gas. The particulate inorganic salt can be sequentially flowed through a plurality of preheating chambers and reaction chambers under an impetus of a density difference of the particulate bed layers, finally achieving the required conversion rate.
    Type: Application
    Filed: August 12, 2019
    Publication date: March 31, 2022
    Inventors: Qi Wang, Changjun Yu
  • Publication number: 20220024762
    Abstract: Disclosed is a system and method for preparing hydrogen chloride and ammonia gas by using ammonium chloride. The system includes a decomposition reactor and at least one regeneration reactor, or includes a reactor that may serve as the decomposition reactor and the regeneration reactor; ammonium chloride in particle form is continuously added to the decomposition reactor via a solid particle feed apparatus, and reacts with molten-state ammonium hydrogen sulfate to generate hydrogen chloride gas and an intermediate material; the intermediate material is discharged to the regeneration reactor, and heated therein to decompose into ammonium hydrogen sulfate and ammonia gas; and the ammonium hydrogen sulfate is returned to the decomposition reactor for recycling.
    Type: Application
    Filed: August 12, 2019
    Publication date: January 27, 2022
    Inventors: Changjun Yu, Qi Wang
  • Publication number: 20210290734
    Abstract: A non-covalent complex of an albumin molecule and a hydrophobic ligand, compositions containing the same, and methods of use thereof are provided. The present complex may find use in delivering the hydrophobic ligand to microorganisms that have albumin-binding outer surfaces, such as a cell wall.
    Type: Application
    Filed: January 21, 2021
    Publication date: September 23, 2021
    Inventors: Ravi Verma, Changjun Yu
  • Patent number: 11105747
    Abstract: Methods and systems for Resonant Raman spectroscopy are provided. Methods according to certain embodiments include irradiating a sample with a monochromatic light source at a first irradiation intensity and a second irradiation intensity, determining the intensity of one or more of the Resonant Raman scattering and fluorescence scattering at the first irradiation intensity and second irradiation intensity, calculating a rate of change of one or more of the intensity of Resonant Raman scattering and fluorescence in response to the change in irradiation intensity from the first irradiation intensity to the second irradiation intensity and comparing one or more of the rate of change in the intensity of Resonant Raman scattering and the rate of change in the intensity of fluorescence scattering with the rate of change in the irradiation intensity by the monochromatic light source to determine the Resonant Raman response of the sample.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: August 31, 2021
    Assignee: Spectral Platforms, Inc.
    Inventors: Ravi Verma, Changjun Yu
  • Patent number: 10940183
    Abstract: A non-covalent complex of an albumin molecule and a hydrophobic ligand, compositions containing the same, and methods of use thereof are provided. The present complex may find use in delivering the hydrophobic ligand to microorganisms that have albumin-binding outer surfaces, such as a cell wall.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: March 9, 2021
    Assignee: Spectral Platforms, Inc.
    Inventors: Ravi Verma, Changjun Yu
  • Publication number: 20200121804
    Abstract: The invention provides compositions comprising a single protein having one or more molecules of a pharmaceutical agent tightly bound therein. The compositions are useful to decrease the toxicity and/or to widen the therapeutic window of the pharmaceutical agent. The invention also provides methods for preparing such a composition.
    Type: Application
    Filed: October 14, 2019
    Publication date: April 23, 2020
    Applicant: Sunstate Biosciences, LLC
    Inventor: Changjun Yu