Patents by Inventor Changjun Yu

Changjun Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9874542
    Abstract: The invention relates to the use of signal processing methods in order to achieve higher signal to noise ratios, to increase the detection limits of target analytes. These techniques include the monitoring of the output signal at higher harmonic frequencies.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: January 23, 2018
    Assignee: CLINICAL MICRO SENSORS, INC.
    Inventors: Robert M. Umek, Gary Blackburn, Bruce D. Irvine, Robert Terbrueggen, Changjun Yu, Jost G. Vielmetter
  • Patent number: 9815712
    Abstract: A resin is provided for selectively binding to perchloride and related anions (e.g., TcO4?, ReO4? and I?) in aqueous solution. The resin may take the form of microparticles or beads. The beads are prepared by cross-linking macromolecules such as hyperbranched PEI, and quaternizing the amines with hydrocarbon substituents.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: November 14, 2017
    Assignees: California Institute of Technology, AquaNano LLC
    Inventors: Mamadou S. Diallo, Changjun Yu, Dennis P. Chen
  • Publication number: 20170182458
    Abstract: The present invention relates to an apparatus for absorbing and mineralizing carbon dioxide comprising a reactor and a three-phase separator, in which said reactor comprises a tower body and a draft tube disposed inside the tower body, a liquid inlet pipe and a gas intake pipe being disposed on the tower body, the outlet ends of the liquid inlet pipe and the gas intake pipe both being located inside the draft tube; and the three-phase separator is disposed at the upper end of the reactor, and a method therefor.
    Type: Application
    Filed: September 26, 2016
    Publication date: June 29, 2017
    Inventors: Guoqiang Jiang, Jiantao Zhang, Changjun Yu, Haichuan Ding
  • Publication number: 20160324933
    Abstract: A non-covalent complex of an albumin molecule and a hydrophobic ligand, compositions containing the same, and methods of use thereof are provided. The present complex may find use in delivering the hydrophobic ligand to microorganisms that have albumin-binding outer surfaces, such as a cell wall.
    Type: Application
    Filed: May 6, 2016
    Publication date: November 10, 2016
    Inventors: Ravi Verma, Changjun Yu
  • Publication number: 20150126391
    Abstract: The invention relates to the use of signal processing methods in order to achieve higher signal to noise ratios, to increase the detection limits of target analytes. These techniques include the monitoring of the output signal at higher harmonic frequencies.
    Type: Application
    Filed: October 14, 2014
    Publication date: May 7, 2015
    Applicant: GenMark Diagnostics Inc.
    Inventors: Robert M. UMEK, Gary Blackburn, Bruce D. Irvine, Robert Terbrueggen, Changjun Yu, Jost G. Vielmetter
  • Publication number: 20150076072
    Abstract: The present disclosure is directed to polymeric beads, methods of making the beads, and methods of using the beads as high-capacity anion exchange materials. In particular, the disclosure provides polymeric beads comprising a cross-linked polyamine and having a crush strength of about 250 g/bead or more. Preferably, the beads are substantially spherical. Also disclosed are polymeric beads comprising a cross-linked polyamine that has a substantial number of both strong base sites and weak base sites. Methods of using the polymeric beads in various industrial applications, such as groundwater remediation, radio waste management, municipal wastewater management, demineralization, toxin removal, mining, food refinery, research, agriculture, and the like, are also disclosed herein.
    Type: Application
    Filed: September 17, 2014
    Publication date: March 19, 2015
    Inventors: Han-Ting Chang, Mamadou Samba Diallo, Daniel Sanchez, Changjun Yu
  • Publication number: 20140158630
    Abstract: A resin is provided for selectively binding to perchloride and related anions (e.g., TcO4?, ReO4? and I?) in aqueous solution. The resin may take the form of microparticles or beads. The beads are prepared by cross-linking macromolecules such as hyperbranched PEI, and quaternizing the amines with hydrocarbon substituents.
    Type: Application
    Filed: May 21, 2013
    Publication date: June 12, 2014
    Inventors: Mamadou S. Diallo, Changjun Yu, Dennis P. Chen
  • Patent number: 8658702
    Abstract: Novel macromolecules for filtering contaminants from water and non-aqueous solutions. Molecules such as polyethyleneimine (PEI) may be functionalized, cross-linked, and/or quaternized to improve their binding capacity or selectivity with particular water contaminants such as bromide, nitrate, and sulfate. The macromolecules may be either recyclable or non-recyclable, and may be recovered or separated from water using means such as ultrafiltration, flocculation, or immobilization on a substrate.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: February 25, 2014
    Inventors: Mamadou Diallo, Changjun Yu
  • Publication number: 20130118986
    Abstract: A resin is provided for selectively binding to certain anions in aqueous solution. The beads are prepared by cross-linking macromolecules such as hyperbranched PEI, and functionalizing with groups containing vicinal diol moieties.
    Type: Application
    Filed: January 4, 2013
    Publication date: May 16, 2013
    Inventors: Mamadou S. Diallo, Changjun Yu, Himanshu Mishra
  • Patent number: 8298521
    Abstract: The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruch's membrane that enables improved diffusional transport between the choroid and retina. The individual is administered an inactivated diffusion-enhancing molecule that becomes associated with the membrane, which is then precisely exposed to an activating energy source, such as light or ultrasound.
    Type: Grant
    Filed: May 23, 2008
    Date of Patent: October 30, 2012
    Assignees: The Regents of the University of California, California Institute of Technology
    Inventors: Daniel M. Schwartz, Scott Fraser, Robert H. Grubbs, Justin P. Gallivan, Changjun Yu
  • Patent number: 8241842
    Abstract: The present invention relates generally to the field of magnetic resonance imaging and, more particularly, to devices and methods used in the observation of the diffusion of molecules across a permeable membrane using magnetic resonance techniques. A typical embodiment of the invention is a method of observing the diffusion of a molecule in a container having a permeable membrane that is disposed between a first solution and a second solution in the container, by using magnetic resonance imaging to obtain an image of the diffusion of the molecule in the first solution across the membrane in to the second solution.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: August 14, 2012
    Assignee: California Institute of Technology
    Inventors: Julian Michael Tyszka, Changjun Yu, Daniel Schwartz, Ilene Sugino, Scott E. Fraser
  • Publication number: 20110315636
    Abstract: Novel macromolecules for filtering contaminants from water and non-aqueous solutions. Molecules such as polyethyleneimine (PEI) may be functionalized, cross-linked, and/or quaternized to improve their binding capacity or selectivity with particular water contaminants such as bromide, nitrate, and sulfate. The macromolecules may be either recyclable or non-recyclable, and may be recovered or separated from water using means such as ultrafiltration, flocculation, or immobilization on a substrate.
    Type: Application
    Filed: December 17, 2010
    Publication date: December 29, 2011
    Applicant: California Institute of Technology
    Inventors: Mamadou Diallo, Changjun Yu
  • Patent number: 7935481
    Abstract: The present invention is directed to methods and compositions for the use of self-assembled monolayers to electronically detect nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs).
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: May 3, 2011
    Assignee: Osmetech Technology Inc.
    Inventors: Robert M. Umek, Gary Blackburn, Bruce D. Irvine, Robert H. Terbrueggen, Changjun Yu, Jost G. Vielmetter
  • Publication number: 20080286255
    Abstract: The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruch's membrane that enables improved diffusional transport between the choroid and retina. The individual is administered an inactivated diffusion-enhancing molecule that becomes associated with the membrane, which is then precisely exposed to an activating energy source, such as light or ultrasound.
    Type: Application
    Filed: May 23, 2008
    Publication date: November 20, 2008
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: DANIEL M. SCHWARTZ, Scott Fraser, Robert H. Grubbs, Justin P. Gallivan, Changjun Yu
  • Patent number: 7384749
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: June 10, 2008
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon F. Kayyem, Stephen D. O'Connor, Michael Gozin, Changjun Yu, Thomas J. Meade
  • Patent number: 7381533
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: June 3, 2008
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon F. Kayyem, Stephen D. O'Connor, Michael Gozin, Changjun Yu, Thomas J. Meade
  • Patent number: 7381404
    Abstract: The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruch's membrane that enables improved diffusional transport between the choroid and retina. The individual is administered an inactivated diffusion-enhancing molecule that becomes associated with the membrane, which is then precisely exposed to an activating energy source, such as light or ultrasound.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: June 3, 2008
    Assignees: The Regents of the University of California, California Institute of Technology
    Inventors: Daniel M. Schwartz, Scott Fraser, Robert H. Grubbs, Justin P. Gallivan, Changjun Yu
  • Patent number: 7125668
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: October 24, 2006
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon Faiz Kayyem, Stephen D. O'Connor, Michael Gozin, Changjun Yu
  • Publication number: 20060211016
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Application
    Filed: January 30, 2006
    Publication date: September 21, 2006
    Inventors: Jon Kayyem, Stephen O'Connor, Michael Gozin, Changjun Yu, Thomas Meade
  • Patent number: 7045285
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: May 16, 2006
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon F. Kayyem, Stephen D. O'Connor, Michael Gozin, Changjun Yu, Thomas J. Meade