Abstract: Several embodiments provided for relate to methods of using of anti-CD19 CAR expressing immune cells in immunotherapy. Provided for herein in several embodiments are immune cell-based (e.g., natural killer (NK) cell) compositions comprising CD19-directed chimeric antigen receptors. In some, embodiments the anti-CD19 binder portion of the CAR is humanized. In several embodiments, the humanized anti-CD19 CAR expressing cells exhibit enhanced expression of the CAR as well as enhanced cytotoxicity and/or persistence.

Abstract: An online monitoring device of 3D printing equipment includes a signal collection module, a signal processing module, a feature extraction module, a monitoring module and a knowledge base module. A vibration signal of a preset component of the 3D printing equipment is collected by a vibration sensor. The collected vibration signal of each preset component is converted from an analog signal to a digital signal and the spectrum characteristics are extracted. Based on the spectrum characteristics of each preset component, the operation state type of the preset component is obtained by a comparative analysis model. The knowledge base module is configured to store newly added samples and initial samples of the 3D printing equipment. The initial samples include spectrum characteristic information and corresponding fault category of known faults, and the newly added samples include spectrum characteristic information and corresponding fault category of new faults.

Abstract: This application relates to an overload and unbalanced load detecting system for a railway and a detecting method. This system includes at least one steel rail. A rail web of each steel rail is provided with two sampling points at two sides between every two adjacent rail sleepers, respectively, and the two sampling points on one side are symmetrically disposed about the steel rail with respect to the two sampling points on the other side. A fiber-optic sensitive element used for continuously measuring a load when a train passes through the two sampling points is obliquely fixed at each sampling point, and two fiber-optic sensitive elements on the same side of each steel rail are disposed at an angle of 90° with each other.

Abstract: The present disclosure provides an anode electrode slurry suspending agent, an anode electrode plate and an energy storage device, the anode electrode slurry suspending agent has a structural formula composed of a main chain containing carbon and a side chain, the side chain comprises a first side chain R1 and a second side chain R2; the first side chain R1 contains —R11—CONH2, the second side chain R2 contains —(C?O)OR21 or —O(C?O)R22, the anode electrode slurry suspending agent can significantly improve coating speed of the anode electrode slurry and can ensure that there is no drying-cracking phenomenon of the anode electrode film at the same time, thereby improving productivity and quality rate of coating process of the anode electrode plate and in turn significantly improving production capacity of the energy storage device.

Abstract: An additive manufacturing apparatus utilizing combined electron beam selective melting and electron beam cutting. One electron beam emitting, focusing, and scanning device (6) is capable of emitting electron beams (67, 68) in three modes of heating, selective melting, and electron beam cutting. The electron beam in the heating mode is emitted to scan and preheat a powder bed (7). The electron beam (67) in the selective melting mode is emitted to scan and melt powder (71) in a section outline to form a section layer of a component. The electron beam (68) in the electron beam cutting mode is emitted to perform one or more cutting scans on inner and outer outlines (74, 75) of a section of the component to obtain accurate and smooth inner and outer outlines of the section. The heating, melting deposition, and outline cutting processes are repeated to obtain a required three-dimensional physical component.

Abstract: The present invention relates to a battery, comprising a positive electrode plate, a separator and a negative electrode plate, wherein the positive electrode plate comprises a positive electrode current collector and at least two layers of positive active materials on at least one surface of the positive electrode current collector in which the underlying positive active material layer in contact with the positive electrode current collector comprises a first positive active material, a first polymer material, and a first conductive material and in which the upper positive active material layer comprises a second positive active material, a second polymer material, and a second conductive material and the first polymer material comprises an oil-dispersible polymer material having a solubility in NMP at 130° C. for 5 minutes, which is 30% or less of the solubility of PVDF under the same conditions. The battery exhibits good safety performance and improved electrical performance.

Abstract: The present invention relates to a positive electrode plate and an electrochemical device. The positive electrode plate includes a current collector, a positive active material layer, and a binding layer disposed between the current collector and the positive active material layer, the binding layer comprising a polymer material, a conductive material, and an inorganic filler, wherein the polymer material comprises a binding layer matrix and the binding layer matrix is an oil-dispersible polymer material having a solubility in NMP at 130 ° C. for 5 minutes, which is 30% or less of the solubility of PVDF under the same conditions. The positive electrode plate can improve the safety performance of the electrochemical device (for example, a capacitor, a primary battery, a secondary battery, or the like) under abnormal conditions such as nailing penetration.

Abstract: Several embodiments disclosed herein relate to the compositions comprising engineered Natural Killer (NK) cells that express a chimeric receptor, the chimeric receptor imparting to the NK cells an enhanced ability to target specific cells, such as cancerous cells or those affected by an infectious disease. Several embodiments relate to NK cells that target cells expressing natural ligands of NKG2D, where the NK cells comprise transmembrane and/or signaling domains that lead to cytotoxic and/or cytolytic effects when the NK cells bind a target cell. Uses of NK cell compositions to treat diseases are also provided for in several embodiments.

Abstract: A hydraulic ship lift, including: a mechanical synchronizing system; a stabilizing and equalizing hydraulic driving system; and a self-feedback stabilizing system. The stabilizing and equalizing hydraulic driving system includes first resistance equalizing members arranged at corners of branch water pipes or/and second resistance equalizing members arranged at bifurcated pipes, circular forced ventilating mechanisms arranged at front of water delivery valves of a water delivery main pipe, and pressure-stabilizing and vibration-reducing boxes arranged behind the water delivery valves. The self-feedback stabilizing system includes a plurality of guide wheels; each guide wheel of the self-feedback stabilizing system is fixed on a ship reception chamber through a supporting mechanism.

Abstract: The present disclosure relates to a method and system for determining a final location associated with a service requester. The method includes obtaining, by at least one computer server of an online transportation service platform, an initial location associated with a service requester; comparing, by the at least one computer server, the initial location with a plurality of candidate locations in a database to generate at least one match result; and determining, by the at least one computer server, a final location based on the at least one match result, wherein the final location is associated with the initial location.

Abstract: A vision-aided inertial navigation system (VINS) comprises an image source for producing image data along a trajectory. The VINS further comprises an inertial measurement unit (IMU) configured to produce IMU data indicative of motion of the VINS and an odometry unit configured to produce odometry data. The VINS further comprises a processor configured to compute, based on the image data, the IMU data, and the odometry data, state estimates for a position and orientation of the VINS for poses of the VINS along the trajectory. The processor maintains a state vector having states for a position and orientation of the VINS and positions within the environment for observed features for a sliding window of poses. The processor applies a sliding window filter to compute, based on the odometry data, constraints between the poses within the sliding window and compute, based on the constraints, the state estimates.

Abstract: The present disclosure relates to a method and system for determining a final location associated with a service requester. The method includes obtaining, by at least one computer server of an online transportation service platform, an initial location associated with a service requester; comparing, by the at least one computer server, the initial location with a plurality of candidate locations in a database to generate at least one match result; and determining, by the at least one computer server, a final location based on the at least one match result, wherein the final location is associated with the initial location.

Abstract: An optical fiber detection device with a steel rail as an elastomer and a railway overload and unbalanced load detection system. The optical fiber detection device includes a shear force detection device, the shear force detection device includes an optical fiber sensitive element which is fixed on a neutral axis of the steel rail through low-energy spot welding.

Abstract: A directed data plan service-launching system includes an intelligent communication terminal, a virtual operator directed data plan system, a virtual operator billing system and an application background server, wherein the intelligent communication terminal calculates and stores mobile network data usage, and periodically uploads the same to the virtual operator directed data plan system with a certain time period, the virtual operator directed data plan system performs bill integration on data of the data usage to form and send a directed data plan bill to the virtual operator billing system, and the virtual operator billing system performs a charge deduction or billing with a specific price on the directed data plan bill; a primary operator billing system performing a charge deduction or billing with a specific price on the directed data plan bill; and an application background service system providing a background service to an application client side.

Abstract: A method includes: receiving, with a computing platform, respective trajectory data and map data independently generated by each of a plurality of vision-aided inertial navigation devices (VINS devices) traversing an environment, wherein the trajectory data specifies poses along a path through the environment for the respective VINS device and the map data specifies positions of observed features within the environment as determined by an estimator executed by the respective VINS device; determining, with the computing platform and based on the respective trajectory data and map data from each of the VINS devices, estimates for relative poses within the environment by determining transformations that geometrically relate the trajectory data and the map data between one or more pairs of the VINS devices; and generating, with the computing platform and based on the transformations, a composite map specifying positions within the environment for the features observed by the VINS devices.

Abstract: The present disclosure relates to vehicle traction apparatus and radiation imaging check systems. One illustrative implementation may comprise two parallel tracks, two sets of traction mechanisms and a driving unit, wherein the tracks are disposed on a ground. The two sets of traction mechanisms may be respectively disposed on the two tracks. Further, the driving unit may be adapted for driving the two sets of traction mechanisms to synchronously move along the two tracks. In some embodiments, each of the two sets of traction mechanisms includes a body, a cantilever, a lifting driving mechanism and a wheel supporting assembly, and may include features such as the body being mounted on the track, the cantilever being disposed parallel to a direction of the tracks, and/or both ends of the cantilever being respectively connected with the lifting driving mechanism and the wheel supporting assembly.

Abstract: A directed data plan service-launching system includes an intelligent communication terminal, a virtual operator directed data plan system, a virtual operator billing system and an application background server, wherein the intelligent communication terminal calculates and stores mobile network data usage, and periodically uploads the same to the virtual operator directed data plan system with a certain time period, the virtual operator directed data plan system performs bill integration on data of the data usage to form and send a directed data plan bill to the virtual operator billing system, and the virtual operator billing system performs a charge deduction or billing with a specific price on the directed data plan bill; a primary operator billing system performing a charge deduction or billing with a specific price on the directed data plan bill; and an application background service system providing a background service to an application client side.

Abstract: A system is provided for supporting cash currency exchange. The system included a server, a first client requesting cash-currency-exchange service, and at least one second client providing the cash-currency-exchange service. The first client sends an exchange-service request of cash currency to the server. The server receives the exchange-service request, obtains the at least one second client, and pushes an exchange-service item corresponding to the exchange-service request to the at least one second client. The second client receives the exchange-service item, and sends a confirmation response to the server. The server pushes information about the at least one second client sending the confirmation response to the first client; and the first client displays the obtained information about the second client, determines a second client as a target client, and triggers an eWallet of the first client to transfer a specified amount to an eWallet of the target client.

Abstract: Vision-aided inertial navigation techniques are described. In one example, a vision-aided inertial navigation system (VINS) comprises an image source to produce image data at a first set of time instances along a trajectory within a three-dimensional (3D) environment, wherein the image data captures features within the 3D environment at each of the first time instances. An inertial measurement unit (IMU) to produce IMU data for the VINS along the trajectory at a second set of time instances that is misaligned with the first set of time instances, wherein the IMU data indicates a motion of the VINS along the trajectory. A processing unit comprising an estimator that processes the IMU data and the image data to compute state estimates for 3D poses of the IMU at each of the first set of time instances and 3D poses of the image source at each of the second set of time instances along the trajectory.

Abstract: The present disclosure provides an anode electrode slurry suspending agent, an anode electrode plate and an energy storage device, the anode electrode slurry suspending agent has a structural formula composed of a main chain containing carbon and a side chain, the side chain comprises a first side chain R1 and a second side chain R2; the first side chain R1 contains —R11—CONH2, the second side chain R2 contains —(C?O)OR21 or —O(C?O)R22, the anode electrode slurry suspending agent can significantly improve coating speed of the anode electrode slurry and can ensure that there is no drying-cracking phenomenon of the anode electrode film at the same time, thereby improving productivity and quality rate of coating process of the anode electrode plate and in turn significantly improving production capacity of the energy storage device.