Abstract: A basal hub for attaching to an infusion base is disclosed. The hub includes a fluid reservoir and pressure actuating device. A septum portion of the reservoir is configured to be opened by a flow cannula that is in fluid communication with an infusion cannula of the infusion base, when the basal hub is attached to the infusion base. The pressure actuating device applies pressure to the fluid reservoir, such that when the septum portion of the fluid reservoir is pierced by the by the flow cannula, liquid stored in the fluid reservoir is released from the fluid reservoir into the infusion cannula of the infusion base via the flow cannula. The basal hub is configured to deliver a basal dose of insulin during periods of inactivity, such as during sleep time.

Abstract: An approach combining immune-based therapies with focused radiation, including stereotactic radiation, to treat cancers is disclosed. The use of focused radiation primes the immune system in a similar manner to vaccines to augment immune-based therapies and can counteract the suppressive effects of a tumor. The combination of focused radiation and immune-based therapies, including administration of at least one immunotherapeutic agent, improves survival compared to each therapy alone and can, in some cases, lead to a durable cure. Accordingly, focused radiation can be an adjuvant for immune-based therapies for treating cancers.

Abstract: A removable mold apparatus that forms a portion of the inner surface contour of an elongated hollow over molded polymeric solar collector distribution manifold and its preferred method of leveraged use that integrates select raw material components and process methods to enhance both manufacturing efficiency and hermetic enjoinment durability, most especially when over molding onto connectively spaced tube absorber constructions.

Abstract: The invention provides provides immunogenic compositions comprising neoplastic cells expressing a cytokine (GM-CSF) formulated with at least one TLR agonist and methods of using the composition to induce or enhance an immune response.

Abstract: A basal hub for attaching to an infusion base is disclosed. The hub includes a fluid reservoir and pressure actuating device. A septum portion of the reservoir is configured to be opened by a flow cannula that is in fluid communication with an infusion cannula of the infusion base, when the basal hub is attached to the infusion base. The pressure actuating device applies pressure to the fluid reservoir, such that when the septum portion of the fluid reservoir is pierced by the by the flow cannula, liquid stored in the fluid reservoir is released from the fluid reservoir into the infusion cannula of the infusion base via the flow cannula. The basal hub is configured to deliver a basal dose of insulin during periods of inactivity, such as during sleep time.

Abstract: Compositions and methods for mass spectroscopy are disclosed. The compositions and methods relate to the analysis of proteins and other biopolymers using mass spectroscopy, particularly matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF MS).

Abstract: An accessory gear box driveshaft in a turbojet engine with intermediate casing, designed to be mounted in a radial arm of the intermediate casing is disclosed. The shaft is mechanically connected, at a first end, to a an engine shaft of the turbojet engine, and is mechanically connected, at a second end, to a gear box. The shaft includes a bevel gear between the two ends, to provide mechanical transmission to an additional accessory. This shaft is notable in that, together with the gear, it is contained in a case forming an oil circuit sealed against the arm. The accessory includes a drive shaft collaborating with the gear of the transmission shaft and forming a modular assembly therewith.

Abstract: This invention is a stand or chock used to park the heaviest of motorcycles. It is extremely easy to enter and exit the chock/stand even when not fixed or bolted to the floor. The smallest of operators will appreciate the ease, safety, and control during the removal of the motorcycle from the chock accomplished with a very light push of a pedal or use of the linear actuators. Commercial establishments such as a motorcycle dealers with many and varying sized motorcycles will like the fact that this motorcycle chock needs no adjustment one size fits all. Because it is so easy to eject the motorcycle from the stand an automatic locking and disconnect system is provided to prevent accidental removal.

Abstract: The invention generally features compositions and methods for modulating an immune response. In particular embodiments, such compositions and methods modulate regulatory T cell suppressive activity.

Abstract: Sifting apparatus, for sifting solid particles from a gaseous or liquid fluid, having a rotating conical filter and fan blade assembly connected to the filter exterior, both rotated together by a motor/pulley assembly, the fan blades slanted in a direction opposite the rotation direction, so that air is drawn through the filter from its interior to its exterior, having an inlet for admission of air only at the narrow end of the filter, and having a receptacle for collection of the particles at the broad end of the filter. Applications include cleaning of particle contaminants from air; cleaning beach sand by sifting out broken glass, sea weed or other debris; extraction of mineral particles from water slurry; collection of soil samples picked up by an air stream; lawn maintenance collection of weeds, leaves and burrs; biohazard removal operations; and an alternative to auger food particle transport in food processing.

Abstract: An aqueous fluid having a viscosity greater than the viscosity of water is contacted with a water soluble material for a time and at a temperature sufficient to reduce the viscosity of the aqueous fluid to a value which is less than about 10 percent of the initial viscosity of the aqueous fluid. The water soluble material is an alkali metal peroxide or a combination of an alkali metal peroxide and a transition metal-containing compound.

Abstract: Sifting apparatus, for sifting solid particles from a gaseous or liquid fluid, having a rotating conical filter and fan blade assembly connected to the filter exterior, both rotated together by a motor/pulley assembly, the fan blades slanted in a direction opposite the rotation direction, so that air is drawn through the filter from its interior to its exterior, having an inlet for admission of air only at the narrow end of the filter, and having a receptacle for collection of the particles at the broad end of the filter. Applications include cleaning of particle contaminants from air; cleaning beach sand by sifting out broken glass, sea weed or other debris; extraction of mineral particles from water slurry; collection of soil samples picked up by an air stream; lawn maintenance collection of weeds, leaves and burrs; biohazard removal operations; and an alternative to auger food particle transport in food processing.

Abstract: Described are uses of A2a adenosine receptor antagonists and agonists to provide long term modulation of immune responses. A2a receptor antagonists in particular are provided to enhance immune responses by reducing T-cell mediated tolerance to antigenic stimuli and agonists are provided to enhance effectiveness of immunosuppressive agents. The application provides methods of treatment and prevention based on the long term effects of the compounds on T cell responses.

Abstract: Sifting apparatus, for sifting solid particles from a gaseous or liquid fluid, having a rotating conical filter and fan blade assembly connected to the filter exterior, both rotated together by a motor/pulley assembly, the fan blades slanted in a direction opposite the rotation direction, so that air is drawn through the filter from its interior to its exterior, having an inlet for admission of air only at the narrow end of the filter, and having a receptacle for collection of the particles at the broad end of the filter. Applications include cleaning of particle contaminants from air; cleaning beach sand by sifting out broken glass, sea weed or other debris; extraction of mineral particles from water slurry; collection of soil samples picked up by an air stream; lawn maintenance collection of weeds, leaves and burrs; biohazard removal operations; and an alternative to auger food particle transport in food processing.

Abstract: The bypass turbomachine comprises, between a primary flowpath (2) and a secondary flowpath (3), a structural intermediate casing (14). A bleed passage (29) allows the diversion of a portion of the gas stream toward the secondary flowpath (3), downstream of support arms (18) situated at the periphery of the intermediate casing. A bleed opening (28) emerges upstream of the support arms (18). A slide valve (22) slides between three positions, namely a closed position in which the slide valve (22) completely blocks off the bleed passage and opening, an intermediate position in which the bleed opening (28) emerging upstream of the support arms (18) is blocked off, while the bleed passage (29) for diverting a portion of the gas stream downstream of the support arms (18) is open, and an open position in which the bleed opening (28) emerging upstream of the support arms (18) and the bleed passage (29) emerging downstream of the support arms are both open.

Abstract: Compositions and methods for mass spectroscopy are disclosed. The compositions and methods relate to the analysis of proteins and other biopolymers using mass spectroscopy, particularly matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF MS).

Abstract: We demonstrate herein that neuritin controls the homeostasis of regulatory T cells in an antigen dependent manner. Based on this discovery, we describe herein the application of neuritin as a therapeutic agent to manipulate antigen specific regulatory T cells in various disease settings is described. Thus manipulation of Treg cells and DCs through neuritin can be used to enhance immunotherapy of autoimmune diseases, cancer and infectious diseases, as well as enhance lymphocyte engraftment in settings of donor lymphocyte infusion, bone marrow transplant, as well as other types of transplants, and adoptive transfer.

Abstract: The present invention relates to a structural or non-structural turbojet engine fan casing connecting arm that also acts as a flow straightener downstream of the fan rotor. Its distinctive feature is that it is constructed to form an acoustic attenuator. In particular, it comprises a closed cavity and perforations on one of the faces so as to form a Helmholtz resonator. The arm forms part of the intermediate casing.

Abstract: The invention relates to a twin spool turbine engine comprising a high-pressure rotor and a low-pressure rotor, at least one accessory gearbox, a drive means, driving coaxial transmission shafts that transmit movement to the accessory gearbox, characterized in that the drive means comprises a high-pressure drive pinion secured to the high-pressure rotor near its upstream end, a low-pressure drive pinion secured to the low-pressure rotor upstream of the high-pressure rotor, and a power take-off module in direct mesh with the drive pinions, driving the transmission shafts. By virtue of the invention, the transmission shafts run coaxial with one another and therefore pass through a single arm. The use of a power take-off module simplifies the mechanism. The turbine engine is simpler to assemble.

Abstract: An arrangement of bearing supports for a rotating shaft mounted on bearings connected to an engine stator structure by bearing supports of which at least one is made up of N>1 elements effectively acting in parallel to simultaneously connect the bearing to the structure, of which N?1 of the N elements form this connection by fusible links, is made up of a first bearing supported by a first bearing support and a second bearing supported by a second bearing support, that of the two bearing supports which makes up the N>1 elements being the second bearing support.