Abstract: Techniques for detecting copy number variations (CNVs) in a genetic sequence, diagnosing disorders caused by CNVs, and treating disorders caused by CNVs are presented. The techniques include using a processor to perform steps of: scanning the genetic sequence to identify genetic regions corresponding to at least one autosomal chromosome, dividing the genetic sequence into bins, calculating a CNV status for each bin of the plurality of bins, and filtering the CNV statuses to identify at least one CNV in the genetic sequence.

Abstract: According to some embodiments, a vibration-isolating system comprises a case, one or more environmental buffers, a platform suspended within the case by a plurality of wire rope isolators, a crumple zone beneath the platform and configured with one or more shock-absorbing structures, and a container assembly configured on the platform. The container assembly is operable to protect a payload comprising a flexible panel. The container assembly comprises a back panel positioned behind the flexible panel and offset by a first substantially airtight compartment, a front panel positioned in front of the flexible panel and offset by a second substantially airtight compartment, and a stiffener panel positioned in front of the front panel and offset by a third substantially airtight compartment.

Abstract: The blade support apparatus involves storing and transporting helicopter blades until the blades are needed for reassembly to the helicopter. The blade support apparatus comprises a lid, a container, a root attachment, and a plurality of attachment bars. One end of the helicopter blade is the root. The blade root is secured to the root plug. A multiplicity of supports secure the container to a transport. The height and angle of each blade in the container can be adjusted, enabling them to conform to the blade curvature which spirals from the blade root to the tip of the blade. Height adjustment to a helicopter blade is achieved by a plurality of contoured pads mounted in the container at varying points along the helicopter blade. Angle adjustment is achieved by a plurality of pivot supports mounted in the container at varying points along the helicopter blade.

Abstract: A method and apparatus of limiting power of a boiling water nuclear reactor system includes a reactor pressure vessel, a reactor core disposed in the reactor pressure vessel, a core shroud surrounding the reactor core, a downcomer region disposed between an inner surface of the reactor pressure vessel and the core shroud, a steam line connected to an upper end of the reactor pressure vessel and a condenser system that receives steam from the reactor pressure vessel. A portion of the condenser system condensate is returned to the reactor pressure vessel of the boiling water reactor inside the core barrel above the core rather than into the downcomer. Returning the condensate in this way increases the effectiveness of an isolation condenser system or if the condensate is a portion of the feedwater from the main condenser it provides an effective means to regulate core flow and core power.

Abstract: Techniques provided herein relate to electronic authentication on public systems. A backend system receives at least one electronic data action request from a publicly available client system that is shared amongst a plurality of users. At least a portion of the primary authentication information is received from a secondary device separate from the publicly available client system. The electronic data action request is authenticated by determining if the primary authentication information matches expected primary authentication information that is expected to complete the electronic data action request. Performance of the electronic data action request is facilitated when the primary authentication information matches the expected primary authentication information.

Abstract: Remote deposit of checks can be facilitated by a financial institution. A customer's general purpose computer and image capture device may be leveraged to capture an image of a check and deliver the image to financial institution electronics. Additional data for the transaction may be collected as necessary. The transaction can be automatically accomplished utilizing the images and data thus acquired.

Abstract: Provided herein, in some embodiments, are methods, compositions, and kits for treating lapatinib-resistant gastric cancer.

Abstract: Redundant heating systems include a plurality of heating circuits to heat a region. Heating circuits include a temperature sensor to sense a temperature of the region, a heating element, a temperature controller to provide power to the heating element based on the sensed temperature of the region, and a latching thermostat in series with the heating element. The latching thermostat consumes power supplied by the temperature controller to the heating element in response to a temperature of the latching thermostat reaching an open latch threshold temperature.

Abstract: A method and apparatus of limiting power of a boiling water nuclear reactor system includes a reactor pressure vessel, a reactor core disposed in the reactor pressure vessel, a core shroud surrounding the reactor core, a downcomer region disposed between an inner surface of the reactor pressure vessel and the core shroud, a steam line connected to an upper end of the reactor pressure vessel and a condenser system that receives steam from the reactor pressure vessel. A portion of the condenser system condensate is returned to the reactor pressure vessel of the boiling water reactor inside the core barrel above the core rather than into the downcomer. Returning the condensate in this way increases the effectiveness of an isolation condenser system or if the condensate is a portion of the feedwater from the main condenser it provides an effective means to regulate core flow and core power.

Abstract: A method of assessing chemical products includes: receiving input data including identification of a chemical substance at a processing device; evaluating a regulatory impact of the chemical substance based on at least one of global regulation data, regional regulation data and jurisdiction-specific regulation data, and outputting a regulatory impact assessment; evaluating potential hazards posed by the chemical substance based on available data related to characteristics of the chemical substance by comparing the characteristics to a plurality of criteria including environmental criteria, toxicity criteria related to effects on human health, and physical criteria related to hazards encountered during material transportation and handling, and outputting a chemical hazard assessment; and generating a chemical assessment report indicating potential impact due to use of the chemical substance, the chemical assessment report indicating chemical assessment results that include the regulatory impact assessment and

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium for receiving an indication of damage to a building from a sensor network associated with the building, where the sensor network is responsive to damage to the building. Determining a location and an extent of the damage to the building based on the indication of damage. Automatically coordinating a repair for the damage in response to determining the location and the extent of the damage.

Abstract: The blade support apparatus relates to capturing and stabilizing airfoils such as helicopter blades to enable ground transport without requiring removal of airfoils or blades with the blade support apparatus and blades in a protective container. The blade support apparatus captures and stabilizes helicopter blades utilizing a support frame with vertical and radial adjustable supports. These supports have contoured padded cradles and means of adjusting the height and angle of the cradles to match the profile being captured. The blade support apparatus enables loading, transport, and unloading of the airfoils for transport in a separate blade container which may either be stand alone or attaches to a helicopter transport apparatus. An alternate embodiment utilizes a support frame which is vertically and radially adjustable. Within the support frame are the same contoured padded swivel cradles which also adjust to the height and angle of the profile being captured.

Abstract: Techniques provided herein relate to registering secondary authentication information with a blockchain. A block chain is stored, having primary authentication information, secondary authentication information, or both that is used in authenticating one or more electronic data action requests provided by a client system to a backend system. The client system, a secondary device, or both registers the secondary device with blockchain node, such that secondary device data is stored as the primary authentication information, the secondary authentication information, or both in the blockchain node.

Abstract: A digital camera processing system with software to manage taking photos with a digital camera. Camera software controls the digital camera. A downloaded software component controls the digital camera software and causes a handheld mobile device to perform operations. The operations may include instructing a user to have the digital camera take photos of a check; displaying an instruction on a display of the handheld mobile device to assist the user in having the digital camera take the photos; or assisting the user as to an orientation for taking the photos with the digital camera. The digital camera processing system may generate a log file including a bi-tonal image formatted as a TIFF image.

Abstract: A pill packet dosage tracking and gating device is provided. The device includes a container, a gate, and a controller. The container includes a reservoir configured to hold a stream of pill packets and an extraction channel configured to guide the passage of the stream of pill packets from the reservoir out of the container. The gate is disposed in the extraction channel and is configured to vertically transition from a closed position blocking extraction of a pill packet of the stream of pill packets and an open position allowing extraction of a pill packet. The controller is configured to monitor the extraction of pill packets and control the transition of the gate from the closed position to the open position.

Abstract: The present innovation pertains to providing an electronic representation of an official document, such as proof of insurance, to an electronic handheld devices: The handheld electronic device may utilize a Web browser to access the representation of the official document, or may request a copy through e-mail, and the representation of the official document may be digitally signed for enhanced proof of authenticity.

Abstract: Disclosed herein are a system, method, and computer-readable medium with instructions for recommending a service provider based on a user's approximate current location. The service provider may be recommended for a service that is verified under a user's insurance policy and is also within proximity to the user's approximate current location. The user's approximate current location may be determined by location-based technology. The entity that receives and/or recommends the service provider may initiate a request for the service from the service provider. Further embodiments are related to routing a call to provide information to the user that is responsive to the user's location-relevant request. For example, systems, such as an automotive telematics system, may request information and be routed to the appropriate division of a user's insurance provider such that the automotive telematics system can provide services to the user that are user-specific (e.g., covered by the user's insurance policy).

Abstract: A system includes a monitoring device coupled to a vehicle. The monitoring device includes a communication interface and one or more processors coupled to the communication interface. The one or more processors receive, via the communication interface, sensor information relating to operating the vehicle. The one or more processors also receive, via the communication interface, contextual information based at least in part on the sensor information relating to operating the vehicle. The one or more processors further generate a risk factor relating to operating the vehicle based at least in part on the sensor information and the contextual information.

Abstract: An integrated circuit, comprising a transistor-based cell comprising a set of fin field effect transistors (Fin FETs) chained together in a first direction, wherein the set of Fin FETs include fins extending longitudinally along the first direction and equally-spaced apart in a second direction orthogonal to the first direction by a fin pitch, and a set of polysilicon gates extending longitudinally along the second direction and equally-spaced apart in the first direction by a poly pitch, wherein a first dimension of the transistor-based cell along the first direction is substantially a first integer multiplied by the poly pitch, and wherein a second dimension of the transistor-based cell along the second direction is substantially a second integer multiplied by the fin pitch. The integrated circuit may include other non-transistor-based cells (e.g., passive cells), such as thin-film resistor or capacitor cells, which are arranged in a two-dimensional array with the transistor-based cell.

Abstract: A security gate actuator includes a main ball screw, a main ball nut, and a drive shaft stage. The main ball screw may further include a circular channel disposed on an outer surface of the main ball screw and at least one drive ball disposed in the circular channel. The main ball nut may be disposed on the main threads of the main ball screw and configured to translate rotational motion of the main ball screw to linear motion of the main ball nut. The drive shaft stage may include a drive shaft end and a drive shaft tube attached to the drive shaft end, the drive shaft end coupled to the main ball nut. The drive ball may push against the drive shaft tube to translate the rotational motion of the main ball screw to rotational motion of the drive shaft tube.