Patents by Inventor Charles S. Zuker

Charles S. Zuker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REGULATION OF IMMUNE RESPONSES THROUGH SELECTIVE NEURAL ACTIVATION
    Publication number: 20240075168
    Abstract: Disclosed herein are methods for regulating an immune response using selective activation of neurons in the caudal nucleus of the solitary tract.
    Type: Application
    Filed: November 9, 2023
    Publication date: March 7, 2024
    Inventors: Charles S. Zuker, Hao Jin
  • NUCLEIC ACIDS ENCODING A G-PROTEIN COUPLED RECEPTOR INVOLVED IN SENSORY TRANSDUCTION
    Publication number: 20190018001
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.
    Type: Application
    Filed: July 20, 2018
    Publication date: January 17, 2019
    Inventors: Charles S. Zuker, Jon Elliot Adler, Juergen Lindemeier
  • G-protein coupled receptor polypeptides involved in sensory transduction
    Patent number: 10031129
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: July 24, 2018
    Assignee: The Regents of the University of California
    Inventors: Charles S. Zuker, Jon Elliot Adler, Juergen Lindemeier
  • METHOD FOR IDENTIFYING COMPOUNDS THAT MODULATE A T2R TASTE RECEPTOR
    Publication number: 20180128842
    Abstract: The invention provides nucleic acid and amino acid sequences for a novel family of taste transduction G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste transduction G-protein coupled receptors.
    Type: Application
    Filed: October 17, 2017
    Publication date: May 10, 2018
    Inventors: Charles S. Zuker, Jon E. Adler, Nick Ryba, Ken Mueller, Mark Hoon
  • Mammalian sweet and amino acid heterodimeric taste receptors comprising T1R3 and T1R1
    Patent number: 9347935
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet or amino acid taste receptors comprising T1R3 and T1R1, two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: May 24, 2016
    Assignees: The Regents of the University of California, The United States of America as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Charles S. Zuker, Jayaram Chandrashekar, Greg Nelson, Yifeng Zhang, Nicholas J. P. Ryba, Mark A. Hoon
  • NUCLEIC ACIDS ENCODING A G-PROTEIN COUPLED RECEPTOR INVOLVED IN SENSORY TRANSDUCTION
    Publication number: 20140065643
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.
    Type: Application
    Filed: September 24, 2013
    Publication date: March 6, 2014
    Applicant: The Regents of the University of California
    Inventors: Charles S. Zuker, Jon Elliot Adler, Juergen Lindemeier
  • Mammalian Sweet and Amino Acid Heterodimeric Taste Receptors Comprising T1R3 and T1R1
    Publication number: 20140024043
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet or amino acid taste receptors comprising T1R3 and T1R1, two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
    Type: Application
    Filed: May 28, 2013
    Publication date: January 23, 2014
    Applicant: The Regents of the University of California
    Inventors: Charles S. Zuker, Jayaram Chandrashekar, Greg Nelson, Yifeng Zhang, Nicholas J. P. Ryba, Mark A. Hoon
  • Methods for identifying compounds which modulate T2R bitter taste receptors
    Patent number: 8580527
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste cell specific G-protein coupled receptors.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: November 12, 2013
    Assignee: The Regents of the University of California
    Inventors: Charles S. Zuker, Jon E. Adler, Mark Hoon, Nick Ryba, Ken Mueller
  • Methods for identifying compounds that modulate sensory signaling through the taste cell specific G-protein coupled receptor GPCR-B4
    Patent number: 8568990
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: October 29, 2013
    Assignee: The Regents of the University of California
    Inventors: Charles S. Zuker, Jon Elliot Adler, Juergen Lindemeier
  • Mammalian sweet and amino acid heterodimeric taste receptors comprising T1R3 and T1R1
    Patent number: 8470970
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet or amino acid taste receptors comprising T1R3 and T1R1, two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
    Type: Grant
    Filed: November 11, 2010
    Date of Patent: June 25, 2013
    Assignees: The Regents of the University of California, The Government of the United States of America
    Inventors: Charles S. Zuker, Jayaram Chandrashekar, Greg Nelson, Yifeng Zhang, Nicholas J. P. Ryba, Mark A. Hoon
  • Mammalian sweet taste receptors
    Patent number: 8198048
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: June 12, 2012
    Assignees: The Regents of the University of California, The United States of America as represented by the Department of Health and Human Services
    Inventors: Charles S. Zuker, Nicholas J. P. Ryba, Gregory A. Nelson, Mark A. Hoon, Jayaram Chandrashekar, Yifeng Zhang
  • NUCLEIC ACIDS ENCODING A G-PROTEIN COUPLED RECEPTOR INVOLVED IN SENSORY TRANSDUCTION
    Publication number: 20120142029
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.
    Type: Application
    Filed: November 4, 2011
    Publication date: June 7, 2012
    Applicant: The Regents of the University of California
    Inventors: Charles S. Zuker, Jon E. Adler, Juergen Lindemeier
  • NUCLEIC ACIDS ENCODING T2R, A NOVEL FAMILY OF TASTE RECEPTORS
    Publication number: 20120135447
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste cell specific G-protein coupled receptors.
    Type: Application
    Filed: October 11, 2011
    Publication date: May 31, 2012
    Applicants: The Govt. of the U.S.A. as represented by the Secretary of the Dept. of Health & Human Services, The Regents of the University of California
    Inventors: Charles S. Zuker, Jon Elliot Adler, Mark Hoon, Nick Ryba, Ken Mueller
  • T2R, A NOVEL FAMILY OF TASTE RECEPTORS
    Publication number: 20120009598
    Abstract: The invention provides nucleic acid and amino acid sequences for a novel family of taste transduction G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste transduction G-protein coupled receptors.
    Type: Application
    Filed: December 13, 2010
    Publication date: January 12, 2012
    Applicant: The Regents of the University of California
    Inventors: Charles S. Zuker, Jon E. Adler, Nick Ryba, Ken Mueller, Mark Hoon
  • Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
    Patent number: 8071743
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: December 6, 2011
    Assignee: The Regents of the University of California
    Inventors: Charles S. Zuker, Jon Elliot Adler, Juergen Lindemeier
  • Mammalian Sweet Taste Receptors
    Publication number: 20110244514
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
    Type: Application
    Filed: March 10, 2010
    Publication date: October 6, 2011
    Inventors: Charles S. Zuker, Nicholas J.P. Ryba, Gregory A. Nelson, Mark A. Hoon, Jayaram Chandrashekar, Yifeng Zhang
  • Mammalian sweet taste receptors
    Patent number: 7977060
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: July 12, 2011
    Assignees: Regents of the University of California, The United States of America as represented by NIH
    Inventors: Charles S. Zuker, Nicholas J. P. Ryba, Gregory A. Nelson, Mark A. Hoon, Jayaram Chandrashekar, Yifeng Zhang
  • Mammalian Sweet and Amino Acid Heterodimeric Taste Receptors Comprising T1R3 and T1R1
    Publication number: 20110151483
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet or amino acid taste receptors comprising T1R3 and T1R1, two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
    Type: Application
    Filed: November 11, 2010
    Publication date: June 23, 2011
    Inventors: Charles S. Zuker, Jayaram Chandrashekar, Greg Nelson, Yifeng Zhang, Nicholas J. P. Ryba, Mark A. Hoon
  • Mammalian T1R3 sweet taste receptors
    Patent number: 7939279
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors, the receptors comprising consisting of a monomer or homodimer of a T1R3 G-protein coupled receptor polypeptide, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
    Type: Grant
    Filed: October 23, 2008
    Date of Patent: May 10, 2011
    Assignees: The Regents of the University of California, The Department of Health and Human Services
    Inventors: Charles S Zuker, Nicholas J. P. Ryba, Isolde Erlenbach, Grace Q Zhao
  • Methods for identifying modulators of SF taste receptor signaling
    Patent number: 7888045
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste cell specific G-protein coupled receptors.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: February 15, 2011
    Assignee: The Regents of the University of California
    Inventors: Charles S. Zuker, Jon Adler, Nick Ryba, Ken Mueller, Mark Hoon