Abstract: A control method of an aerial vehicle. The aerial vehicle includes a gimbal carrying an image acquisition device. The method includes obtaining a preliminary-flight trajectory of the aerial vehicle and control information of the gimbal that are set by a user, automatically controlling the aerial vehicle to move according to the preliminary-flight trajectory, and automatically controlling the gimbal and the image acquisition device to photograph a target object according to the control information of the gimbal.

Abstract: The present invention features methods and compositions for the intranasal, sublingual, and subcutaneous administration of bumetanide for the treatment of subjects suffering from edema refractory to oral diuretics.

Abstract: Provided is a color conversion substrate. The color conversion substrate includes: a base substrate; a reflective isolation portion on a side of the base substrate, a plurality of pixel apertures being defined in the reflective isolation portion, wherein the plurality of pixel apertures include a plurality of first-type pixel apertures arranged in arrays and a plurality of second-type pixel apertures arranged in arrays, and a plurality of lines of the first-type pixel apertures and a plurality of lines of the second-type pixel apertures are alternately arranged; and a color conversion layer, including a first color conversion pattern, a second color conversion pattern, and a transmission pattern, wherein the first color conversion pattern and the transmission pattern are disposed in different first-type pixel apertures, and the second color conversion pattern is disposed in the plurality of second-type pixel apertures.

Abstract: An organic light emitting diode display panel, a manufacturing method thereof and a display device are provided, the organic light emitting diode display panel includes: a pixel defining layer, which includes a first opening, a second opening and a pixel defining structure between the first opening and the second opening, the first opening is provided with a light emitting layer and a first electrode which are stacked, the second opening is not provided with the light emitting layer; a first lateral edge of the pixel defining structure adjacent to the first opening forms a first included angle with a plane parallel to a main surface of the base substrate, and a second lateral edge of the pixel defining structure adjacent to the second opening forms a second included angle with a plane parallel to the base substrate, the first included angle is smaller than the second included angle.

Abstract: The present invention provides a lipid nanoparticle comprising a fentanyl hapten, and a T helper peptide and/or an adjuvant, wherein the fentanyl hapten is conjugated to the outer surface of the lipid nanoparticle, and wherein the T helper peptide and/or the adjuvant is/are encapsulated within the lipid nanoparticle. The invention further provides a pharmaceutical composition comprising the lipid nanoparticle and uses thereof for inducing an immune response against fentanyl and the prevention or treatment of a fentanyl abuse disorder or a fentanyl addiction or a fentanyl overdose in a subject. Further provided herein is a method for preparing the lipid nanoparticle of the invention.

Abstract: Provided is a corn detasseling inspection robot and a method for performing detasseling by using the same. The corn detasseling inspection robot includes a control terminal, a moving device and a detasseling device; wherein the control terminal includes a detection module, a detasseling control module and a tassel recognition module; the detection module is configured for acquiring an image of a corn plant; the tassel recognition module is configured for judging whether there is a corn tassel on the corn plant based on the image of the corn plant, and determining a position of a root of the corn tassel based on a detasseling operation point prediction model in the case where there is the corn tassel on the corn plant; and the detasseling control module is configured for controlling the moving device and using the detasseling device to perform detasseling based on the position of the root.

Abstract: A drug conjugate includes a structure shown by the following formula: Z-(linker-[R]m)n. In the formula, Z is a drug compound, R is a sugar, and m and n are independently an integer from 1 to 6. The drug compound Z is a hepatitis virus targeting drug, a hepatitis B virus (HBV) drug, an inhibitor of apoptosis protein (IAP) antagonist, a multidrug resistance (MDR) inhibitor, or analogues, precursors, prodrugs, derivatives thereof.

Abstract: A method for screening tobacco resistance against root-knot nematode based on intensive seedling production is provided. The method has two biological properties: inducing and stimulating the hatching of nematode eggs by host root exudates, and easily infecting the root cap elongation zone by hatched second-instar larvae. The second-instar larvae hatched by the root-knot nematode eggs are continuously inoculated. After that, under cultivating the infected tobacco seedlings in shallow water infiltrating and humidifying substrate, the created temperature, humidity and air permeability conditions are suitable for disease induction. After disease investigation, disease index is calculated, and the resistance of tested cultivars is evaluated according to the disease index. The method features simple operation, high selection efficiency, and high accuracy and reproducibility.

Abstract: The present invention provides an anti-B7H4 antibody-drug conjugate specifically binding to B7H4, and a composition comprising same, wherein the structure of the anti-B7H4 antibody-drug conjugate is shown as formula (I-1). The present invention further provides a method and use of the antibody-drug conjugate provided herein. The anti-B7H4 antibody-drug conjugate of the present invention has better inhibitory activity against tumor cell proliferation in vitro and a better tumor inhibition effect in vivo.

Abstract: The present disclosure provides a locking base assembly. The locking base assembly includes: a base plate for placing an object thereon; and a locking mechanism mounted on the base plate for locking and unlocking the object. The locking mechanism includes: at least one releasing operation element capable of sliding between a locking position and an unlocking position with respect to the base plate; and at least one locking element is slidably disposed on the base plate. The locking element is capable of locking the object when the releasing operation element is in the locking position. The locking element moves along with movement of the releasing operation element to unlock (i.e., release) the object when the releasing operation element is operated to move from the locking position to the unlocking position. The present disclosure also provides a wheeled carrying apparatus including the locking base assembly.

Abstract: The present invention relates to an antibody-drug conjugate and an application thereof, and specifically provides the antibody-drug conjugate, a pharmaceutically acceptable salt and solvate thereof, or a solvate of the salt. The antibody-drug conjugate has the structure represented by formula I, wherein Ab is an anti-Claudin 18.2 antibody. The antibody-drug conjugate of the present invention has good tumor cell growth inhibition activity in vivo and in vitro, low toxicity, and good application prospects.

Abstract: A method of sampling a target tissue in an animal body, comprising the steps of inserting a endoscope-needle system into the animal body, guiding the endoscope-needle system along a path toward the target tissue using a Doppler-based optical coherence tomography (OCT) system coupled with machine-learning-based computer-aided diagnosis (ML-CAD), wherein the Doppler-based OCT system coupled with ML-CAD enables the identification of blood vessels along the path in advance of the needle tip of the endoscope-needle system thereby substantially avoiding damage to the blood vessels along the path as the needle tip of the endoscope-needle system is guided into the target tissue, after the needle tip is guided into the target tissue, and removing a tissue sample from the target tissue.

Abstract: A reversibly adhesive film, comprising: at least two hydroxyl-bearing polymer chains being crosslinked by one or more boronic ester bonds, the film having accessible hydroxyl groups at a surface of the film. An reversible adhesive, comprising: a first film layer, the first film layer comprising at least two first hydroxyl-bearing polymer chains crosslinked by first crosslinks that comprise one or more boronic ester bonds; and a second film layer, the first second layer comprising at least two second hydroxyl-bearing polymer chains crosslinked by second crosslinks that comprise one or more boronic ester bonds, wherein (1) the first hydroxyl-bearing polymer chains differ from the second hydroxyl-bearing polymer chains in one or more of composition and concentration, or (2) the boronic ester bonds are present in the first film layer at a different density than the boronic ester bonds in the second film layer, or (3) both (1) and (2).

Abstract: A cleaning system and a cleaning method are provided. The cleaning system includes a main body, an air suctioning device, a light source, an optical sensor, a memory and a processing unit. The air suctioning device includes an air flow passage and a fan-motor assembly that is disposed in the air flow passage and generates a suction force to suction outside air through the air flow passage. The light source emit light to the air flow passage. The optical sensor captures a plurality of successive image frames from the air flow passage. The processing unit is configured to: obtain first and second image frames from the successive image frames; compare the first image frame with the second image frame to identify dust particles; obtain a particle feature of the dust particles; and determine a current cleanness condition according to the particle feature.

Abstract: Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.

Abstract: A method and system for extracting a target signal based on maximum correlated kurtosis deconvolution are provided, which relate to a field of signal processing. The method includes: obtaining a microwave signal of a brain of a subject to be tested; filtering the microwave signal by using maximum correlated kurtosis deconvolution to obtain a filtered signal; performing mode decomposition on the filtered signal by using a complete ensemble empirical mode decomposition with adaptive noise to obtain a target response signal; and performing image reconstruction on the target response signal by using a delay sum beamforming to obtain a target bleeding image.

Abstract: Disclosed is an acylated insulin, a pharmaceutical formulation thereof, a pharmaceutical composition thereof with a long-acting GLP-1 compound, and a medical use of the acylated insulin, the pharmaceutical formulation and the pharmaceutical composition. Compared with insulin degludec or other insulin derivatives, the acylated insulin has an unexpected, significantly increased drug effect, a longer duration of action, a longer in vivo half-life, an excellent bioavailability, as well as better physical and chemical stabilities.

Abstract: A blood physiological parameter sensing device includes a housing, a flow channel structure, a control unit and a sensing unit. The flow channel structure is disposed in the housing and forms a channel for a liquid to be measured to pass. The control unit is disposed in the housing. The sensing unit is disposed in the housing, is electrically connected to the control unit, and has a sensing end. The sensing end passes through the flow channel structure, is configured in the channel, and has an electrochemical sensing material. The electrochemical sensing material is used to exchange electrons with the blood physiological parameter in the liquid to be measured to produce redox reactions to generate current or voltage change parameters. The sensing unit transmits the current or voltage change parameters to the control unit, which obtains a blood physiological parameter concentration value to achieve instantaneous and continuous monitor the patients.

Abstract: An intelligent separation method of peanut kernel and red coat, feeding peanuts to be removed red coats into a device for a gas explosion of the red coats of the peanuts, to complete a preliminary separation of kernels and the red coats of the peanuts; feeding the primarily separated kernels and peanut red coats of the peanuts into the drying device to fully separate the red coats from the kernels; delivering the fully separated peanut kernels and red coats of the peanuts into a negative pressure adsorption device to collect respectively the fully separated kernels and red coats of the peanuts with different densities and qualities by a negative pressure adsorption mode, finally obtaining the kernels of the peanuts without the red coats, and the red coats of the peanuts respectively.

Abstract: A method for measuring periodontal disease and treating diseases associated therewith includes: obtaining B-mode ultrasound images of a dentition and periodontium of a patient; identifying gingival margin (GM), alveolar bone crest (ABC), cementoenamel junction (CEJ), periodontal ligament (PDL), and gingival edge (GE) biomarkers on the B-mode ultrasound images, the GE biomarker being a part of periodontal soft tissue most distal from a tooth surface; evaluating a metric associated with periodontal disease using one or more of the GM, ABC, CEJ, PDL and GE biomarkers and based at least in part on the evaluating, performing an act that implements and/or adjusts a therapeutic treatment of a periodontal disease.