Abstract: The present disclosure discloses a use of a drug combination containing an anti-CD20 antibody drug conjugate (ADC) in the preparation of a drug for treating Non-Hodgkin Lymphoma (NHL). The drug combination includes the anti-CD20 ADC and at least one therapeutic agent. The drug combination therapy has better efficacy than the existing clinical first-line standard therapy. Additionally, it offers several advantages, including fewer types of drugs, shorter infusion time, lower safety risks, and better economic accessibility.

Abstract: The present disclosure relates, in part, to risankizumab compositions having a reduced level of hitchhiker protein PLA2, Poloxamer 188, and/or decreased immunogenicity.

Abstract: The present disclosure relates to a non-destructive in-situ measurement device and method based on Raman analysis. The device comprises: a laser light source that emits a laser beam; a focusing component that focuses the laser beam above a movable sample stage, with the focal plane of the focusing component positioned at an initial position. During measurement, the focal plane is controlled to move from the initial position to the surface, side, or bottom of the structure under test. The movable sample stage holds the sample to be measured and can move in a plane perpendicular and/or parallel to the optical axis. The axis of the structure under test is parallel to the optical axis and located within the laser beam's focal region. A detection module collects specific Raman scattering signals returned from the sample under test, and the structure's planar and three-dimensional parameters are determined based on the collected results.

Abstract: The present invention discloses a safe and efficient method for hypoxia-induced adipogenic differentiation of cells and use thereof, belonging to the technical field of cell culture. The method involves expanding cells to a certain number in a reactor in a suspension environment, and inducing adipogenic differentiation of the cells in suspension by reducing a dissolved oxygen level to hypoxia. The method induces adipogenic differentiation of cells solely through physical factors. Compared to traditional chemical induction adipogenic differentiation methods, no exogenous reagents are introduced during a differentiation process, and food safety is ensured. By using the method, cell adipogenic differentiation can be completed in 4-6 days, and expansion and adipogenic differentiation of cells can be completed in about 10 days, thus accelerating differentiation.

Abstract: Some embodiments of the present disclosure relate to material handling equipment, a controller and a pose detection method. The material handling equipment includes a controller, and the controller is configured to execute a program instruction to implement the following actions: acquiring a point cloud of a detection object provided with one or more reflective components; extracting, from the point cloud of the detection object, point clouds corresponding to the one or more reflective components; determining a target plane region according to the point clouds corresponding to the one or more reflective components; and determining a pose of the detection object according to a pose of the target plane region. Compared with the prior art, the material handling equipment, the controller and the pose detection method provided by some embodiments of the present disclosure improve the universality, accuracy and efficiency of the detection object recognition in warehouse logistics.

Abstract: A cross arm assembly includes: at least one insulator, an end of the at least one insulator being configured to be connected with a tower body of a transmission tower, forming a low-voltage end of the cross arm assembly, and another end of the at least one insulator being configured as an end of the cross arm assembly for hanging a conductor, forming a high-voltage end of the cross arm assembly; and a high-voltage end fitting, comprising a fixing portion, the high-voltage end fitting being configured to be connected with the other end of the at least one insulator and hang at least one conductor.

Abstract: Embodiments of this application provide a photographing method and an electronic device. The electronic device may recognize a capturing intention of a user, decide, based on a time of manual capture, a manually-captured highlight frame from image frames obtained within a short time before manual capture and image frames obtained within a short time after manual capture, for example, decide a manually-captured highlight frame from image frames obtained within 1 second before manual capture and image frames obtained within 5 seconds after manual capture. In addition, the electronic device may further search for an automatically-captured highlight frame based on a time of enabling auto capture. In this way, while an automatically-captured highlight photo is generated and a user triggers manual capture, the electronic device may store both the automatically-captured highlight photo and the manually-captured highlight.

Abstract: The present disclosure discloses a use of anti-CD20 ADC in the preparation of a drug for treating NHL, and the drug has excellent clinical efficacy and safety in treating a R/R NHL patient after receiving at least two standard treatments.

Abstract: Disclosed in the present invention are a polypeptide and a polypeptide composition specifically binding to a SARS-CoV-2 spike protein, and preparation methods and the uses thereof. By means of binding to S1 protein, the polypeptide and the polypeptide composition can block the binding of SARS-CoV-2 virus to a key target protein angiotensin-converting enzyme 2 (ACE2) protein on the surface of a host cell thereof, thereby providing a feasible targeting drug for the treatment of Coronavirus disease 2019.

Abstract: A metal-containing photoresist film may be deposited on a semiconductor substrate. Unintended metal-containing material may form on internal surfaces of a process chamber during deposition, bevel and backside cleaning, exposure, baking, development, etch, or other photolithography operations. A dry chamber clean may remove the unintended metal-containing material in multiple thermal steps. The dry chamber clean may remove some of the unintended metal-containing material by exposure to an etch gas such as a halide-containing gas. The remainder of the unintended metal-containing material may be removed by cycling between exposure to a modifying gas such as air and exposure to an etch gas.

Abstract: An embodiment of the present disclosure provides a plugin adding method and apparatus, an electronic device, and a storage medium. The method comprises: presenting a target page, wherein at least one plugin adding area is provided in the target page; receiving a plugin adding operation acting on the plugin adding area, and presenting a plugin editing area corresponding to the plugin adding operation; and receiving a plugin editing operation acting on the plugin editing area, generating a target plugin based on edited plugin information, and adding the target plugin to the plugin adding area.

Abstract: A method includes acquiring a to-be-used execution project flow, where the to-be-used execution project flow includes multiple to-be-used flow nodes; in response to detecting that an operation on at least one to-be-used flow node is a preset operation, updating the to-be-used execution project flow, and in response to detecting that a target control is triggered, using the updated to-be-used execution project flow as a target execution project flow.

Abstract: A battery transportation protection device. The battery transportation protection device includes a case, where the case includes a case cover and a case body. The case body has a first opening, and the case cover covers the first opening to define, together with the case body, a first accommodation cavity for accommodating a battery. A pressure relief channel is formed inside the case cover, and the pressure relief channel is in communication with the first accommodation cavity and configured to discharge gas from the first accommodation cavity.

Abstract: Provided are a copper-doped silicon carbide composite, a preparation method and use thereof. The preparation method for the copper-doped silicon carbide composite includes subjecting a silicon- and carbon-containing precursor to arc plasma pyrolysis to obtain the copper-doped silicon carbide composite, where the silicon-and carbon-containing precursor includes an organochlorosilane; and a material of an anode used for the arc plasma pyrolysis includes copper.

Abstract: A secondary battery includes a packaging bag, an electrode assembly, a first tab, a first insulation tape, and a second insulation tape. The electrode assembly is accommodated in the packaging bag. The first tab is electrically connected to the electrode assembly and protrudes from the packaging bag along a first direction. The electrode assembly assumes a jelly-roll structure and includes a first end surface, a first side surface, a first curved surface, and a second side surface. The first side surface, the first curved surface, and the second side surface are disposed around a periphery of the first end surface. The first insulation tape includes a tape body and a first protruding portion. The tape body is bonded to the first side surface, the first curved surface, and the second side surface separately. The first protruding portion exceeds a negative electrode plate of the electrode assembly along the first direction.

Abstract: A recommendation system implements a linkage (connectivity) score learning algorithm for user-item interaction bipartite graphs that is combined with a lightweight iterative degree update process in the bipartite graph where the degrees used in the scoring formula are updated several times to exploit local graph structures without any node (user/item) modeling. In the linkage score learning algorithm, for user u1 and item i2, the predicted linkage score between them is the sum over all sub-scores of each 3-step linkage path between u1 and i2. The linkage score learning algorithm pre-defines 6 learnable candidate parameter values, selects the best combination of parameters, and predicts a set of linkage scores that can be used for recommendation systems. The linkage score learning algorithm addresses the problem of link prediction by predicting new links in a graph that do not already exist in training data.

Abstract: The embodiment of the disclosure provides a liquid cooling cabinet bearing apparatus comprising: a rack comprising a plurality of vertical support structures and at least one layer of mounting bases supported by the vertical support structures, each layer of mounting bases comprise a plurality of mounting bases for bearing corresponding liquid cooling cabinet respectively, and at least part of the vertical support structures is provided with a pipeline arrangement channel; a cooling water supply pipe comprising a water supply horizontal pipe, at least one water supply longitudinal pipe and a water supply branch pipe; a cooling water return pipe, comprising a water return horizontal pipe, at least one water return longitudinal pipe and a water return branch pipe, and an electrical line disposed outside the pipeline arrangement channel and adapted to be electrically connected to the corresponding liquid cooling cabinet.

Abstract: A positive electrode sheet in the secondary battery includes a positive electrode current collector, a positive electrode active material layer, and a positive electrode tab, where the positive electrode active material layer is disposed on at least one surface of the positive electrode current collector. The positive electrode active material layer is provided with a first groove exposing the positive electrode current collector. The positive electrode tab is disposed in the first groove and connected to the positive electrode current collector. An insulating tape is provided on each of a surface of the positive electrode tab and a region, corresponding to the first groove, of a surface of the positive electrode sheet away from the positive electrode tab. A melting point of the insulating tape is 250° C. to 450° C. An electrolyte includes carbonate and carboxylate.