Patents by Inventor Chitra Subramanian

Chitra Subramanian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11891378
    Abstract: The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: February 6, 2024
    Assignees: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., COA THERAPEUTICS, INC.
    Inventors: Richard E. Lee, Rajendra P. Tangallapally, Charles O. Rock, Suzanne Jackowski, Anne V. Edwards, Mi Kyung Yun, Chitra Subramanian, Robert Zamboni, T. Jagadeeswar Reddy
  • Publication number: 20230321092
    Abstract: The present disclosure relates to methods of treating a coenzyme A reduction, elevation, sequestration, toxicity, or redistribution (CASTOR) disease such as, for example, defects in fatty acid oxidation enzymes, methylmalonic acidemia, glutaric acidemia, propionic academia, and HMG-CoA lyase, via small molecule modulators of CoA levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 6, 2022
    Publication date: October 12, 2023
    Inventors: Suzanne JACKOWSKI, Charles O. ROCK, Richard E. LEE, Lalit Kumar SHARMA, Mi Kyung YUN, Chitra SUBRAMANIAN, Rajendra P. TANGALLAPALLY, Anne V. EDWARDS, Robert ZAMBONI, T. Jagadeeswar REDDY, Jiuyu LIU
  • Patent number: 11547709
    Abstract: The present disclosure relates to methods of treating a coenzyme A reduction, elevation, sequestration, toxicity, or redistribution (CASTOR) disease such as, for example, defects in fatty acid oxidation enzymes, methylmalonic acidemia, glutaric acidemia, propionic academia, and HMG-CoA lyase, via small molecule modulators of CoA levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: January 10, 2023
    Assignees: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., COA THERAPEUTICS, INC.
    Inventors: Suzanne Jackowski, Charles O. Rock, Richard E. Lee, Lalit Kumar Sharma, Mi Kyung Yun, Chitra Subramanian, Rajendra P. Tangallapally, Anne V. Edwards, Robert Zamboni, T. Jagadeeswar Reddy, Jiuyu Liu
  • Publication number: 20220185796
    Abstract: The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: March 26, 2020
    Publication date: June 16, 2022
    Inventors: Ragendra P. Tangallapally, Richard E. Lee, Anne V. Edwards, Charles O. Rock, Suzanne Jackowski, Mi Kyung Yun, Chitra Subramanian
  • Publication number: 20220157657
    Abstract: Embodiments of the invention include a method of singulating IC chips from a wafer. The method can include receiving the wafer having a substrate formed under active layers. The wafer includes a chip that includes a first portion of the active layers and a first portion of the substrate. A separation trench is formed by using an etch operation to remove a first segment of the active layers and a first segment of the substrate that are beneath a first separation channel of the wafer. The separation trench separates the first portion of the active layers from a remaining portion of the active layers; and separates the first portion of the substrate from a remaining portion of the substrate. The first IC chip is seperated from the wafer by removing a first section of the remaining portion of the substrate that is underneath the first portion of the substrate.
    Type: Application
    Filed: November 13, 2020
    Publication date: May 19, 2022
    Inventors: Cyril Cabral, JR., Frank Robert Libsch, Chitra Subramanian, Peter Jerome Sorce, Paul Alfred Lauro, John M. Papalia
  • Patent number: 11313826
    Abstract: An integrated chemical sensor device includes a chemical sensor comprising at least one transistor and having an external sensing surface electrically coupled to a node of the at least one transistor. There is an initialization circuit connected to the base of the at least one transistor configured to set an operating point for the at least one transistor. There is a temperature sensor control circuit coupled to the chemical sensor circuit. The temperature sensor includes a temperature sensor, an analog-to-digital (A/D) converter coupled to the temperature sensor, and a proportional-to-absolute-temperature (PTAT) circuit configured to generate a PTAT reference voltage for temperature compensation. The temperature sensor control circuit is configured to compensate for a change in temperature of the at least one transistor.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: April 26, 2022
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Chitra Subramanian, Sufi Zafar
  • Patent number: 11190362
    Abstract: Devices, computer-implemented methods, and systems that can facilitate radio frequency identification components are provided. According to an embodiment, a device can comprise a memory that can be coupled to an integrated circuit device that can have a processor and an accelerator component that can execute a cryptographic module. The device can further comprise a radio frequency identification device that can be coupled to the integrated circuit device that can communicate with a radio frequency identification reader device based on the cryptographic module.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: November 30, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Chitra Subramanian, Seiji Munetoh, Frank Robert Libsch, Daniel Joseph Friedman, Ghavam G. Shahidi, Arun Paidimarri
  • Publication number: 20210246113
    Abstract: The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 14, 2020
    Publication date: August 12, 2021
    Inventors: Lalit Kumar SHARMA, Richard E. LEE, Charles O. ROCK, Suzanne JACKOWSKI, Mi Kyung YUN, Chitra SUBRAMANIAN, Jiuyu LIU
  • Patent number: 11074968
    Abstract: A system and method for storing data that includes at least one memory device having a plurality of memory cells for storing data; and a memory control circuit that manages the read current and read pulse width applied to the memory cells, wherein the at least one memory device has a read current circuit configured to utilize adjustments to at least one of the read current or the read pulse width applied to the memory cells. In response to a request to read a group of the memory cells, the memory control circuit in an example, in response to determining that a comparative temperature value exceeds a first threshold, is configured to perform at least one of reducing the read current and/or increasing the read pulse width to be applied to the group of memory devices to be read.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: July 27, 2021
    Assignee: International Business Machines Corporation
    Inventors: Saravanan Sethuraman, Karthick Rajamani, Venkata K. Tavva, Hillery Hunter, Chitra Subramanian
  • Publication number: 20210158866
    Abstract: A system and method for storing data that includes at least one memory device having a plurality of memory cells for storing data; and a memory control circuit that manages the read current and read pulse width applied to the memory cells, wherein the at least one memory device has a read current circuit configured to utilize adjustments to at least one of the read current or the read pulse width applied to the memory cells. In response to a request to read a group of the memory cells, the memory control circuit in an example, in response to determining that a comparative temperature value exceeds a first threshold, is configured to perform at least one of reducing the read current and/or increasing the read pulse width to be applied to the group of memory devices to be read.
    Type: Application
    Filed: November 22, 2019
    Publication date: May 27, 2021
    Inventors: Saravanan Sethuraman, Karthick Rajamani, Venkata K. Tavva, Hillery Hunter, Chitra Subramanian
  • Publication number: 20210061788
    Abstract: The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 26, 2018
    Publication date: March 4, 2021
    Inventors: Richard E. LEE, Rajendra P. TANGALLAPALLY, Charles O. ROCK, Suzanne JACKOWSKI, Anne V. EDWARDS, Mi Kyung YUN, Chitra SUBRAMANIAN, Robert ZAMBONI, T. Jagadeeswar REDDY
  • Publication number: 20210023081
    Abstract: The present disclosure relates to methods of treating a coenzyme A reduction, elevation, sequestration, toxicity, or redistribution (CASTOR) disease such as, for example, defects in fatty acid oxidation enzymes, methylmalonic acidemia, glutaric acidemia, propionic academia, and HMG-CoA lyase, via small molecule modulators of CoA levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 26, 2018
    Publication date: January 28, 2021
    Inventors: Suzanne JACKOWSKI, Charles O. ROCK, Richard E. LEE, Lalit Kumar SHARMA, Mi Kyung YUN, Chitra SUBRAMANIAN, Rajendra P. TANGALLAPALLY, Anne V. EDWARDS, Robert ZAMBONI, T. Jagadeeswar REDDY, Jiuyu LIU
  • Patent number: 10899734
    Abstract: The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: January 26, 2021
    Assignee: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
    Inventors: Lalit Kumar Sharma, Richard E. Lee, Charles O. Rock, Suzanne Jackowski, Mi Kyung Yun, Chitra Subramanian, Jiuyu Liu
  • Patent number: 10884918
    Abstract: A semiconductor structure includes a first processor on a first die of a substrate. There is a second processor on a second die of the substrate. There is a one-time programmable (OTP) memory programming circuit, outside of the first and second die, and shared by the first and second processors. Each of the first and second processors include a one-time programmable (OTP) memory. The OTP memory programming circuit is configured to program each OTP memory.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: January 5, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Chitra Subramanian, Seiji Munetoh, Ghavam Shahidi
  • Publication number: 20200340942
    Abstract: An integrated chemical sensor device includes a chemical sensor comprising at least one transistor and having an external sensing surface electrically coupled to a node of the at least one transistor. There is an initialization circuit connected to the base of the at least one transistor configured to set an operating point for the at least one transistor. There is a temperature sensor control circuit coupled to the chemical sensor circuit. The temperature sensor includes a temperature sensor, an analog-to-digital (A/D) converter coupled to the temperature sensor, and a proportional-to-absolute-temperature (PTAT) circuit configured to generate a PTAT reference voltage for temperature compensation. The temperature sensor control circuit is configured to compensate for a change in temperature of the at least one transistor.
    Type: Application
    Filed: April 24, 2019
    Publication date: October 29, 2020
    Inventors: Chitra Subramanian, Sufi Zafar
  • Publication number: 20200242022
    Abstract: A semiconductor structure includes a first processor on a first die of a substrate. There is a second processor on a second die of the substrate. There is a one-time programmable (OTP) memory programming circuit, outside of the first and second die, and shared by the first and second processors. Each of the first and second processors include a one-time programmable (OTP) memory. The OTP memory programming circuit is configured to program each OTP memory.
    Type: Application
    Filed: January 28, 2019
    Publication date: July 30, 2020
    Inventors: Chitra Subramanian, Seiji Munetoh, Ghavam Shahidi
  • Publication number: 20200220736
    Abstract: Devices, computer-implemented methods, and systems that can facilitate radio frequency identification components are provided. According to an embodiment, a device can comprise a memory that can be coupled to an integrated circuit device that can have a processor and an accelerator component that can execute a cryptographic module. The device can further comprise a radio frequency identification device that can be coupled to the integrated circuit device that can communicate with a radio frequency identification reader device based on the cryptographic module.
    Type: Application
    Filed: January 3, 2019
    Publication date: July 9, 2020
    Inventors: Chitra Subramanian, Seiji Munetoh, Frank Robert Libsch, Daniel Joseph Friedman, Ghavam G. Shahidi, Arun Paidimarri
  • Patent number: 10679912
    Abstract: A chip intermediate body includes a semiconductor region including plural chip areas. The chip areas respectively are cut out as semiconductor chips. A cut region is provided along edges of the chip areas, the cut region being cut to cut out the semiconductor chips. A contact region is provided opposite to the chip areas across the cut region, the contact region being configured to be contacted by a probe of a test unit to test the chip areas, and electric wiring is provided continuously with the cut region to connect the chip areas and the contact region.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: June 9, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Akihiro Horibe, Yasuteru Kohda, Seiji Munetoh, Chitra Subramanian, Kuniaki Sueoka
  • Patent number: 10475497
    Abstract: Precharging circuits and techniques are presented for use with magnetic memory devices in order to speed up access to the memory cells for reading and writing. Including precharging in the sense amplifiers used to access the memory cells enables self-referenced read operations to be completed more quickly than is possible without precharging. Similarly, precharging can also be used in conjunction with write-back operations in order to allow the data state stored by magnetic tunnel junctions included in the memory cells to be changed more rapidly.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: November 12, 2019
    Assignee: Everspin Technologies, Inc.
    Inventors: Syed M. Alam, Chitra Subramanian
  • Publication number: 20190300499
    Abstract: The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: June 23, 2017
    Publication date: October 3, 2019
    Applicant: St. Jude Children's Research Hospital
    Inventors: Lalit Kumar Sharma, Richard E. Lee, Charles O. Rock, Suzanne Jackowski, Mi Kyung Yun, Chitra Subramanian, Jiuyu Liu