Patents by Inventor Chong Han

Chong Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10457648
    Abstract: The present disclosure relates to processes for preparing (cyclopentyl[d]pyrimidin-4-yl)piperazine compounds, and more particularly relates to processes for preparing (R)-4-(5-methyl-7-oxo-6,7-dihydro-5H-cyclopenta[d] pyrimidin-4-yl)piperazine and N-protected derivatives thereof, which may be used as an intermediate in the synthesis of Ipatasertib (i.e., (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)-propan-1-one). The present disclosure additionally relates to various compounds that are intermediates employed in these processes.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: October 29, 2019
    Assignees: GENENTECH INC., F. HOFFMANN-LA ROCHE AG
    Inventors: Francis Gosselin, Chong Han, Hans Iding, Reinhard Reents, Scott Savage, Beat Wirz
  • Publication number: 20190292201
    Abstract: Methods of making benzoxazepin oxazolidinone compounds as well as synthetic intermediates are described, including compound 18, having the structure:
    Type: Application
    Filed: June 14, 2019
    Publication date: September 26, 2019
    Applicant: Genentech, Inc.
    Inventors: Francis GOSSELIN, Chong HAN, Theresa CRAVILLION, Sean M. KELLY, Scott SAVAGE
  • Patent number: 10381293
    Abstract: An integrated circuit (IC) package includes a first leadframe having a top surface and a bottom surface. An IC die has an active side coupled to the first leadframe bottom surface and has a back side. A second leadframe has a top surface and a bottom surface. The back side of said IC chip is coupled to the top surface of the second leadframe.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: August 13, 2019
    Assignee: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Lee Han Meng@Eugene Lee, Chong Han Lim, You Chye How
  • Patent number: 10329616
    Abstract: The present disclosure relates to a primer set for preparation of a library used for next generation sequencing (NGS), and a method and a kit for making an NGS library using the same. The method for making the next generation sequencing (NGS) library using the primer set according to the present disclosure is able to simply analyze large amounts of samples as compared to the existing method for making a library, which is effectively usable for analysis of target DNA sequences or for database construction, in large amounts of samples.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: June 25, 2019
    Assignee: REPUBLIC OF KOREA (NATIONAL FORENSIC SERVICE DIRECTOR, MINISTRY OF PUBLIC ADMINISTRATION & SECURITY)
    Inventors: Yang-Han Lee, Chong Min Chung, Min-Hee Kim, Eu-Ree An, Min Young Lee
  • Patent number: 10329288
    Abstract: The invention provides processes of preparation thereof useful in the preparation of compounds that can be used as CHK1 inhibitors.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: June 25, 2019
    Assignees: Genentech, Inc., Array BioPharma Inc.
    Inventors: Chong Han, Keena Green, Francis Gosselin, Michelangelo Scalone, Paul J. Nichols, Weidong Liu, Keith L. Spencer, Zackary D. Crane, Peter J. Stengel, Sagar Shakya
  • Patent number: 10332509
    Abstract: Embodiments of end-to-end deep learning systems and methods are disclosed to recognize speech of vastly different languages, such as English or Mandarin Chinese. In embodiments, the entire pipelines of hand-engineered components are replaced with neural networks, and the end-to-end learning allows handling a diverse variety of speech including noisy environments, accents, and different languages. Using a trained embodiment and an embodiment of a batch dispatch technique with GPUs in a data center, an end-to-end deep learning system can be inexpensively deployed in an online setting, delivering low latency when serving users at scale.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: June 25, 2019
    Assignee: Baidu USA, LLC
    Inventors: Bryan Catanzaro, Jingdong Chen, Mike Chrzanowski, Erich Elsen, Jesse Engel, Christopher Fougner, Xu Han, Awni Hannun, Ryan Prenger, Sanjeev Satheesh, Shubhabrata Sengupta, Dani Yogatama, Chong Wang, Jun Zhan, Zhenyao Zhu, Dario Amodei
  • Patent number: 10321426
    Abstract: An apparatus and method for detecting synchronization and signals using block data processing in a receiving system are provided. To process an input signal, a cumulative matrix is obtained from an input vector signal for each frame generated from the signal. A primary eigenvector is extracted from the cumulative matrix, and the maximum value of a correlation vector is calculated from the extracted primary eigenvector. A time delay is detected by comparing the calculated maximum value of the correlation vector with a first threshold value, and a delay correlation vector is calculated from the detected time delay. Finally, synchronization and signals are detected by comparing the calculated delay correlation vector with a second threshold value.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: June 11, 2019
    Assignees: Samsung Electronics Co., Ltd., Electronics and Telecommunications Research Institute
    Inventors: Chang Wahn Yu, Youn Ok Park, Chong Hyun Lee, Jun-Woo Kim, Seungjae Bahng, Byung-Han Ryu, Jung Pil Choi, Young Jo Bang
  • Patent number: 10319374
    Abstract: Embodiments of end-to-end deep learning systems and methods are disclosed to recognize speech of vastly different languages, such as English or Mandarin Chinese. In embodiments, the entire pipelines of hand-engineered components are replaced with neural networks, and the end-to-end learning allows handling a diverse variety of speech including noisy environments, accents, and different languages. Using a trained embodiment and an embodiment of a batch dispatch technique with GPUs in a data center, an end-to-end deep learning system can be inexpensively deployed in an online setting, delivering low latency when serving users at scale.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: June 11, 2019
    Assignee: Baidu USA, LLC
    Inventors: Bryan Catanzaro, Jingdong Chen, Mike Chrzanowski, Erich Elsen, Jesse Engel, Christopher Fougner, Xu Han, Awni Hannun, Ryan Prenger, Sanjeev Satheesh, Shubhabrata Sengupta, Dani Yogatama, Chong Wang, Jun Zhan, Zhenyao Zhu, Dario Amodei
  • Publication number: 20180339997
    Abstract: The present invention relates to crystalline polymorph forms of (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide (GDC-0077), having the structure, Formula I: or stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, and processes of preparing the polymorph forms.
    Type: Application
    Filed: April 26, 2018
    Publication date: November 29, 2018
    Applicant: Genentech, Inc.
    Inventors: Paroma Chakravarty, Chong Han, Sean M. Kelly, Karthik Nagapudi, Scott Savage
  • Publication number: 20180258054
    Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
    Type: Application
    Filed: October 12, 2017
    Publication date: September 13, 2018
    Applicants: Array BioPharma Inc., Genentech, Inc.
    Inventors: David Askin, Chong Han, Jonathan W. Lane, Travis Remarchuk, Sagar Shakya, C. Gregory Sowell, Keith L. Spencer, Peter J. Stengel
  • Patent number: 9975856
    Abstract: Processes are described for the preparation of estrogen receptor modulating compound, (E)-3-(4-((E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl)phenyl)acrylic acid I: and salts thereof, and intermediates useful for the preparation of I.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: May 22, 2018
    Assignee: Genentech, inc.
    Inventors: Stephan Bachmann, Serena Maria Fantasia, Francis Gosselin, Chong Han, Stefan Hildbrand, Theresa Humphries, Christian Jenny, Ngiap-Kie Lim, Andrew McClory, Christian Moessner, Pankaj Rege, Scott Savage, Haiming Zhang
  • Patent number: 9969735
    Abstract: Processes are described for the preparation of tricyclic lactam compound of Formula (I), having the structure and intermediates useful for the preparation of (I).
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: May 15, 2018
    Assignee: GENENTECH, INC.
    Inventors: Ngiap-Kie Lim, Haiming Zhang, Chong Han
  • Patent number: 9906934
    Abstract: The present invention provides a smart meter including a wireless-communication chip, a wired-communication chip and a microprocessor. The microprocessor receives a data transmission request and determines whether the data type of the data transmission request is mobile data, meter information, or emergency meter information. According to the data type, the microprocessor will select either the wireless-communication chip or the wired-communication chip to transmit the data which corresponds to the data transmission request.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: February 27, 2018
    Assignee: WISTRON NEWEB CORP.
    Inventors: Cheng-Kun Lo, Chong-Han Lai, Chien-Cheng Kuo
  • Publication number: 20170313704
    Abstract: Processes are described for the preparation of tricyclic lactam compound of Formula (I), having the structure and intermediates useful for the preparation of (I).
    Type: Application
    Filed: July 18, 2017
    Publication date: November 2, 2017
    Applicant: Genentech, Inc.
    Inventors: Ngiap-Kie Lim, Haiming Zhang, Chong Han
  • Patent number: 9790190
    Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: October 17, 2017
    Assignees: Array BioPharma Inc., Genentech, Inc.
    Inventors: David Askin, Chong Han, Jonathan W. Lane, Travis Remarchuk, Sagar Shakya, C. Gregory Sowell, Keith L. Spencer, Peter J. Stengel
  • Publication number: 20170277231
    Abstract: A removable storage cartridge system may include a linear push-push mechanism comprising a carriage having a lock bar and a lock bar spring, and an enclosure having a mounting bracket having a lock guide. The lock guide is configured to interact with the lock bar and spring such that, in response to a first pushing force, reception of the carriage into the mounting bracket positions the carriage into a locked position within the enclosure and, in response to a second pushing force, the carriage is released from the locked position and ejected from the system.
    Type: Application
    Filed: March 22, 2016
    Publication date: September 28, 2017
    Inventors: John L. Harting, Thomas F. Meehan, Herman Chong-Han Yang
  • Patent number: 9772662
    Abstract: A removable storage cartridge system may include a linear push-push mechanism comprising a carriage having a lock bar and a lock bar spring, and an enclosure having a mounting bracket having a lock guide. The lock guide is configured to interact with the lock bar and spring such that, in response to a first pushing force, reception of the carriage into the mounting bracket positions the carriage into a locked position within the enclosure and, in response to a second pushing force, the carriage is released from the locked position and ejected from the system.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: September 26, 2017
    Assignee: Western Digital Technologies, Inc.
    Inventors: John L. Harting, Thomas F. Meehan, Herman Chong-Han Yang
  • Publication number: 20170247338
    Abstract: The present disclosure relates to processes for preparing (cyclopentyl[d]pyrimidin-4-yl)piperazine compounds, and more particularly relates to processes for preparing (R)-4-(5-methyl-7-oxo-6,7-dihydro-5H-cyclopenta[d] pyrimidin-4-yl)piperazine and N-protected derivatives thereof, which may be used as an intermediate in the synthesis of Ipatasertib (i.e., (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)-propan-1-one). The present disclosure additionally relates to various compounds that are intermediates employed in these processes.
    Type: Application
    Filed: September 25, 2015
    Publication date: August 31, 2017
    Inventors: Francis Gosselin, Chong Han, Hans Iding, Reinhard Reents, Scott Savage, Beat Wirz
  • Publication number: 20170247337
    Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
    Type: Application
    Filed: May 11, 2017
    Publication date: August 31, 2017
    Applicants: Array BioPharma Inc., Genentech, Inc.
    Inventors: David Askin, Chong Han, Jonathan W. Lane, Travis Remarchuk, Sagar Shakya, C. Gregory Sowell, Keith L. Spencer, Peter J. Stengel
  • Publication number: 20170213781
    Abstract: An integrated circuit (IC) package includes a first leadframe having a top surface and a bottom surface. An IC die has an active side coupled to the first leadframe bottom surface and has a back side. A second leadframe has a top surface and a bottom surface. The back side of said IC chip is coupled to the top surface of the second leadframe.
    Type: Application
    Filed: January 21, 2016
    Publication date: July 27, 2017
    Inventors: Lee Han Meng@Eugene Lee, Chong Han Lim, You Chye How