Patents by Inventor Chong Hui

Chong Hui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20210155603
    Abstract: Provided are compounds useful for treating of cancer and methods for treating of cancer, comprising administering to a subject in need thereof a compound described therein.
    Type: Application
    Filed: June 29, 2020
    Publication date: May 27, 2021
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
    Publication number: 20200397768
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Application
    Filed: September 4, 2020
    Publication date: December 24, 2020
    Inventor: Chong-Hui Gu
  • Pharmaceutical compositions of therapeutically active compounds
    Patent number: 10799490
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: October 13, 2020
    Assignee: Agios Pharmaceuticals, Inc.
    Inventor: Chong-Hui Gu
  • Therapeutically active compounds and their methods of use
    Patent number: 10730854
    Abstract: Provided are compounds useful for treating of cancer and methods for treating of cancer, comprising administering to a subject in need thereof a compound described therein.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: August 4, 2020
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
    Publication number: 20190336487
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Application
    Filed: July 2, 2019
    Publication date: November 7, 2019
    Inventor: Chong-Hui Gu
  • Pharmaceutical compositions of therapeutically active compounds
    Patent number: 10449184
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: October 22, 2019
    Assignee: Agios Pharmaceuticals, Inc.
    Inventor: Chong-Hui Gu
  • PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF
    Publication number: 20190274959
    Abstract: The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.
    Type: Application
    Filed: March 12, 2019
    Publication date: September 12, 2019
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Eleni DOKOU, Shahla JAMZAD, John P. CAESAR, JR., Majed FAWAZ, Laura DAS, Chong-Hui GU, Patricia Nell HURTER, Meghna Jai ISRANI, Meghan M. JOHNSTON, Dragutin KNEZIC, Andrew G. KUZMISSION, HongRen WANG
  • Pharmaceutical composition and administrations thereof
    Patent number: 10272046
    Abstract: The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: April 30, 2019
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Eleni Dokou, Shahla Jamzad, John P. Caesar, Jr., Majed Fawaz, Laura Das, Chong-Hui Gu, Patricia Nell Hurter, Meghna Jai Israni, Meghan M. Johnston, Dragutin Knezic, Andrew G. Kuzmission, HongRen Wang
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20180370951
    Abstract: Provided are compounds useful for treating of cancer and methods for treating of cancer, comprising administering to a subject in need thereof a compound described therein.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 27, 2018
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
    Publication number: 20180325880
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Application
    Filed: April 10, 2018
    Publication date: November 15, 2018
    Inventor: Chong-Hui Gu
  • Therapeutically active compounds and their methods of use
    Patent number: 10093654
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: October 9, 2018
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • Alignment device and manufacturing method for polymer stabilized vertical alignment liquid crystal panel
    Patent number: 9995968
    Abstract: A manufacturing method for a polymer stabilized vertical alignment (PS-VA) liquid crystal panel includes: forming a first substrate of PS-VA liquid crystal panel, the first substrate including a common electrode; forming a second substrate of the PS-VA liquid crystal panel, the second substrate including a pixel electrode; forming a liquid crystal layer between the first and second substrates, the liquid crystal layer containing negative liquid crystal molecules and ultraviolet-curable resin; applying an electrical voltage that exceeds a rotation threshold of the liquid crystal layer to the common electrode and the pixel electrode; and reciprocally moving an ultraviolet light source, which is composed of at least two ultraviolet light sources that are distributed parallel to each other in a first direction and respectively extend in a second direction, in such a direction as to have accumulation of ultraviolet light received by the ultraviolet-curable resin of the liquid crystal layer homogenized.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: June 12, 2018
    Assignee: SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.
    Inventor: Chong-Hui Yin
  • Pharmaceutical compositions of therapeutically active compounds
    Patent number: 9968595
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: May 15, 2018
    Assignee: AGIOS PHARMACEUTICALS, INC.
    Inventor: Chong-Hui Gu
  • TABLET COMPOSITIONS
    Publication number: 20180064715
    Abstract: Provided herein is a tablet comprising 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 6, 2017
    Publication date: March 8, 2018
    Inventors: Sreenivas S. Bhat, Scott Burnside, Darshan Parikh, Chong-Hui Gu, Syed Altaf
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20170305885
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein.
    Type: Application
    Filed: July 13, 2017
    Publication date: October 26, 2017
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • Therapeutically active compounds and their methods of use
    Patent number: 9738625
    Abstract: Provided are isocitrate dehydrogenase 2 (IDH2) inhibitor compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein. Also provided are polymorphic forms of the IDH2 inhibitor compounds characterized by X Ray powder diffraction patterns, having improved physicochemical properties that influence in vivo dissolution rate for formulation purposes.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: August 22, 2017
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • ALIGNMENT DEVICE AND MANUFACTURING METHOD FOR POLYMER STABILIZED VERTICAL ALIGNMENT LIQUID CRYSTAL PANEL
    Publication number: 20170160595
    Abstract: A manufacturing method for a polymer stabilized vertical alignment (PS-VA) liquid crystal panel includes: forming a first substrate of PS-VA liquid crystal panel, the first substrate including a common electrode; forming a second substrate of the PS-VA liquid crystal panel, the second substrate including a pixel electrode; forming a liquid crystal layer between the first and second substrates, the liquid crystal layer containing negative liquid crystal molecules and ultraviolet-curable resin; applying an electrical voltage that exceeds a rotation threshold of the liquid crystal layer to the common electrode and the pixel electrode; and reciprocally moving an ultraviolet light source, which is composed of at least two ultraviolet light sources that are distributed parallel to each other in a first direction and respectively extend in a second direction, in such a direction as to have accumulation of ultraviolet light received by the ultraviolet-curable resin of the liquid crystal layer homogenized.
    Type: Application
    Filed: February 15, 2017
    Publication date: June 8, 2017
    Inventor: CHONG-HUI YIN
  • PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF
    Publication number: 20170100340
    Abstract: The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.
    Type: Application
    Filed: June 13, 2016
    Publication date: April 13, 2017
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Eleni DOKOU, Shahla JAMZAD, John P. CAESAR, JR., Majed FAWAZ, Laura DAS, Chong-Hui GU, Patricia Nell HURTER, Meghna Jai ISRANI, Meghan M. JOHNSTON, Dragutin KNEZIC, Andrew G. KUZMISSION, HongRen WANG
  • PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
    Publication number: 20170014396
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Application
    Filed: March 13, 2015
    Publication date: January 19, 2017
    Applicant: AGIOS PHARMACEUTICALS, INC
    Inventor: Chong-Hui Gu
  • PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
    Publication number: 20170007661
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Application
    Filed: March 13, 2015
    Publication date: January 12, 2017
    Inventor: Chong-Hui Gu