Abstract: A chunk format for a large-scale, high data throughput router includes a preamble that allows each individual chunk to have clock and data recovery performed before the chunk data is retrieved. The format includes a chunk header that contains information specific to the entire chunk. A chunk according to the present format can contain multiple packet segments, with each segment having its own packet header for packet-specific information. The format provides for a scrambler seed which allows scrambling the data to achieve a favorable zero and one balance as well as minimal run lengths. There can be a random choice of available scrambler seeds for any particular chunk to avoid malicious forcing of zero and one patterns or run lengths of bit zeroes and ones. There are a chunk cyclical redundancy check (CRC) as well as forward error correction (FEC) bytes to detect and/or correct any errors and also to insure a high degree of data and control integrity.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinase of the following structural formula: The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

Abstract: The present invention provides a marking system adapted for coating a surface of a substrate in which a drying agent is used. According to a first aspect of the invention, a binder layer, such as paint, is applied to the surface. A drying agent is dispensed into the spray of a binder and becomes incorporated with the binder on the substrate surface. The incorporation of the drying agent into the binder prior to application on the surface provides improved mixing of the drying agent and binder and improved performance. According to a second aspect of the invention, a combination of optical elements and a drying agent are stored in a common hopper and are dispensed into the spray of the binder and become incorporated with the binder on the substrate surface. The mixture of optical elements and drying agent prevents coagulation of the drying agent and the resulting clogging of the dispenser.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

Abstract: A chunk format for a large-scale, high data throughput router includes a preamble that allows each individual chunk to have clock and data recovery performed before the chunk data is retrieved. The format includes a chunk header that contains information specific to the entire chunk. A chunk according to the present format can contain multiple packet segments, with each segment having its own packet header for packet-specific information. The format provides for a scrambler seed which allows scrambling the data to achieve a favorable zero and one balance as well as minimal run lengths. There are forward error correction (FEC) bytes as well as a chunk cyclical redundancy check (CRC) to detect and/or correct any errors and also to insure a high degree of data and control integrity. Advantageously, a framing symbol inserted into the chunk format itself allows the receiving circuitry to identify or locate a particular chunk format.

Abstract: A patient interface device adapted to provide an interface between a cornea and a surgical laser system. A frame has an applanation end and an attachment end which is adapted to couple to the surgical laser system. A skirt is affixed to the applanation end of the frame and is adapted to seal against the anterior surface of the cornea to form a chamber. A lens is disposed near the applanation end of the frame and is supported by a flexible support which affixes the lens to the frame.

Abstract: A container for carrying and pouring flowable materials having a bucket portion with a side portion, a closed bottom portion and an upper rim area at least partially defining an open top; a handle attached near or on the upper rim area; at least three gripping surfaces located in the closed bottom portion of the bucket portion to permit multiple means of gripping the container. A method for dispensing flowable materials having the steps of gripping a handle rotatably affixed to a container having material therein with a first hand, wherein at least a portion of the handle is located above a discharge opening of the container; gripping a gripping surface located about the middle of the bottom of the container with a second hand; and tipping the container to discharge material from within the container using the first hand and the handle as a pivot point while lifting the bottom of the container with the second hand gripping the gripping surface.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.