Abstract: The invention relates to a method for operating a transversal guidance system of a motor vehicle through two independent channels to perform automatic transversal guidance interventions. Through the first channel, transversal interventions are performed via a first transversal guidance actuator controlled by means of a driver-operated steering handle. Through the second channel, a vehicle system sets a target roll angle, and a second transversal guidance actuator is controlled by a transversal guidance system that performs a transversal guidance intervention based on the roll angle. The vehicle system displays the roll angle as a notification to the driver of the transversal guidance intervention. The invention also relates to a motor vehicle configured to perform the method.

Abstract: A housing for a high-frequency chip in a radar device for level measurement is provided, including a high-frequency chip having a high-frequency terminal and a supply terminal; horizontal metal layers; vertical metal connecting lines; and an external supply terminal configured to connect the chip to a circuit board of the device, the chip being attached to one of the horizontal metal layers in an electrically conductive manner, and being embedded in a polymer compound, which is located between the horizontal metal layers, the supply terminal being connected to the external supply terminal via at least one of the horizontal metal layers and via at least one of the vertical metal connecting lines, and the high-frequency terminal being connected to an antenna configured to decouple and receive radar waves, via at least one of the horizontal metal layers and/or via at least one of the vertical metal connections.

Abstract: The present disclosure relates to tumour therapy. In one aspect, the present disclosure relates to conjugates of an amatoxin and a target-binding moiety, e.g. an antibody, connected by certain linkages, which are useful in the treatment of cancer. In a further aspect the invention relates to pharmaceutical compositions comprising such conjugates.

Abstract: A level radar is switchable between pulsed and FMCW radar methods. For example, the radar device may include two separate front ends which can be activated selectively via a logic control system. Upon switching to the respective other measurement principle, the evaluation software is also adapted accordingly. In this way, it is possible to use advantageous properties of both measurement methods in a targeted manner.

Abstract: The invention relates to tumor therapy. In one aspect, the present invention relates to conjugates of an amatoxin and a target-binding moiety, e.g. an antibody, connected by certain linkages, which are useful in the treatment of cancer and other disorders and diseases. In a further aspect the invention relates to pharmaceutical compositions comprising such conjugates.

Abstract: The invention relates to conjugates comprising amatoxins and antibodies, in particular amatoxins linked to antibodies comprising specific cysteine residues.

Abstract: A radar fill level measurement device can be provided, which comprises a frequency synthesizer configured to generate an oscillator signal, a high-frequency signal generation module configured to generate a transmission signal based on the oscillator signal, and an energy-supply module configured to supply electrical energy to the frequency synthesizer and the high-frequency signal generation module. Associated methods and computer-accessible medium can also be provided. The frequency synthesizer can comprise a control device, a reference oscillator and a phase-locked loop. The phase-locked loop can comprise a phase-locked device and an oscillator. The phase-locked loop can be configured to adjust a frequency of the oscillator signal to a target value, and the phase-locked device can be configured to provide a control signal for the control device when the frequency of the oscillator signal has reached the target value.

Abstract: An exemplary fill level measurement device comprising a radar module can be provided, along with method, computer-executable instructions and computer-readable medium. The radar module can comprise a receiving channel for receiving a radar signal reflected by a filling medium. The fill level measurement device can also comprise a test module for testing the functionality of the receiving channel. The test module can comprise a test input (for feeding in a test signal having a test frequency, and a feeding-in apparatus configured to feed at least part of the test signal into the receiving channel. The feeding-in apparatus can be configured to superpose and/or combine the test signal with the radar signal reflected by the filling medium. The receiving channel of the radar module can further comprise a mixing device having an intermediate frequency output.

Abstract: A manual work station, in particular a manual work station for manufacturing and/or a manual work station for packaging, comprising a work area accessible to a worker, the manual work station having at least one robotic arm, the manual work station having a safety device, which is designed in such a way that the robotic arm cooperates in a contact-free manner with the worker in the work area. The invention furthermore relates to a control unit for controlling the sequencing of a manual work station.

Abstract: A fill level measuring device designed for the generation and emission of a transmission signal, wherein the transmission signal includes at least one frequency ramp. In order to determine the level of a filling material in a vessel, only frequencies within a fundamental frequency interval are used. In this case, the minimal frequency of the fundamental frequency interval is greater than the minimal frequency of the frequency ramp and/or the maximal frequency of the fundamental frequency interval is smaller than the maximal frequency of the frequency ramp. The approach provides a reduction of power peaks in the frequency spectrum of the mean power of fill level measuring devices, which peaks result from times in which the fill level measuring device emits a constant frequency before the beginning of or after a frequency ramp.

Abstract: The invention relates to novel methods for synthesizing a synthon for ?,?-dihydroxyisoleucine 1 (CAS No. 55399-94-5] as building block for the synthesis of amatoxins, and for novel methods for synthesizing amatoxins using such building block.

Abstract: A technique for generating a data set that geometrically defines a bone cut configuration for transverse maxillary distraction is using a computer-implemented method. An aspect of the technique comprises creating a numeric model of a maxilla based on patient-specific data of the maxilla. The numeric model is representative of mechanical properties of the maxilla. Based on the numeric model thus generated, one or more cut configurations for one or more bone cuts on at least one of a left hand side and a right hand side of the maxilla are determined. Each cut configuration has been determined to compensate for asymmetric mechanical properties of the maxilla. In a further step, a data set indicative of the one or more cut configurations thus determined is generated. The data set may be used to create a surgical template or jig, for computer-assisted surgery or a surgical navigation system.

Abstract: The present invention relates to the use of substantially linear polypropyleneimine as a hardener for epoxy resins, and also to a corresponding curable composition, to the curing thereof, and to the cured epoxy resin obtainable therefrom.

Abstract: Embodiments in accordance with the present invention provide for the use of polycycloolefins in electronic devices and more specifically to the use of such polycycloolefins as gate insulator layers used in the fabrication of electronic devices, the electronic devices that encompass such polycycloolefin gate insulator and processes for preparing such polycycloolefin gate insulator layers and electronic devices encompassing such layers.

Abstract: Embodiments in accordance with the present invention provide for the use of polycycloolefins in electronic devices and more specifically to the use of such polycycloolefins as interlayers applied to fluoropolymer layers used in the fabrication of electronic devices, the electronic devices that encompass such polycycloolefin interlayers and processes for preparing such polycycloolefin interlayers and electronic devices.

Abstract: The invention relates to novel methods for synthesizing a synthon for ?,?-dihydroxyisoleucine 1 (CAS No. 55399-94-5] as building block for the synthesis of amatoxins, and for novel methods for synthesizing amatoxins using such building block.

Abstract: The present invention relates to a process for preparing polyamines having a mean molecular weight of ?203 g/mol, in which the deviation from the mean molecular weight per ° C. of change in the reaction temperature is <19% of the mean molecular weight, by polycondensation of diamines in the liquid phase in the presence of heterogeneous catalysts based on transition metals of the eighth to eleventh transition groups of the Periodic Table of the Elements and hydrogen at temperatures of 100 to 250° C. and pressures in the range from 60 to 150 bar, to the polyamines obtainable by this process, and to the use of the polyamines.

Abstract: Embodiments in accordance with the present invention provide for the use of polycycloolefins in electronic devices and more specifically to the use of such polycycloolefins as interlayers applied to fluoropolymer layers used in the fabrication of electronic devices, the electronic devices that encompass such polycycloolefin interlayers and processes for preparing such polycycloolefin interlayers and electronic devices.

Abstract: A sensor module for integration within a seat assembly is provided. The sensor module comprises a temperature and/or humidity sensor (21) and a separate sensor support (51) for mechanically supporting said temperature and/or humidity sensor. The sensor support is configured to be arranged on or in a support layer below an air-permeable cover of the seat assembly.

Abstract: The present invention relates to a process for producing nylon-6,6 by a) providing a muconic acid starting material selected from muconic acid, esters of muconic acid, lactones of muconic acid and mixtures thereof, b) subjecting the muconic acid starting material provided in step a) at least to some extent to a reaction with hydrogen in the presence of at least one hydrogenation catalyst Hb) to give adipic acid, c1) subjecting the muconic acid starting material provided in step a) to some extent to a reaction with hydrogen in the presence of at least one hydrogenation catalyst Hc1) to give 1,6-hexanediol, or c2) subjecting the adipic acid obtained in step b) to some extent to a reaction with hydrogen in the presence of at least one hydrogenation catalyst Hc2) to give 1,6-hexanediol, d) subjecting the 1,6-hexanediol obtained in step c1) or c2) to amination in the presence of an amination catalyst to obtain hexamethylenediamine, e) subjecting the hexamethylenediamine obtained in step d) and at least a portion o