Abstract: Provided herein are anti-TREM1 antibodies and related methods of making and using anti-TREM1 antibodies. Also provided are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, e.g., cancer, comprising killing, disabling, or depleting non-stimulatory myeloid cells using an anti-TREM1 antibody or antigen binding fragment thereof.

Abstract: The present invention is directed to anti-PVRIG antibodies and methods of using same.

Abstract: The present invention is directed to triple combination therapies with anti-TIGIT antibodies, anti-PVRIG antibodies, and checkpoint inhibitors, including anti-PD-1 or anti-PD-L1 antibodies.

Abstract: The present invention is directed to triple combination therapies with anti-TIGIT antibodies, anti-PVRIG antibodies, and checkpoint inhibitors, including anti-PD-1 or anti-PD-L1 antibodies.

Abstract: A mobile device that includes a camera and an extended reality software application program is employed by a user in an operating environment, such as an industrial environment. The user aims the camera within the mobile device at optical data markers, such as QR codes, that are associated with machines in the environment. The mobile device acquires an image from the camera and decodes the optical data markers included in the acquired image. The mobile device queries the data intake and query system for the values of metrics for the machines associated with the decoded optical data markers. Upon receiving the metric values from the data intake and query system, the mobile device generates AR overlays and superimposes the AR overlays onto the acquired image. The mobile device displays the image with superimposed AR overlays on a display device.

Abstract: Provided herein are anti-TREM1 antibodies and related methods of making and using anti-TREM1 antibodies. Also provided are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, e.g., cancer, comprising killing, disabling, or depleting non-stimulatory myeloid cells using an anti-TREM1 antibody or antigen binding fragment thereof.

Abstract: Methods, systems, and media for providing dynamic media sessions with video stream transfer features are provided. In some embodiments, the methods include: receiving an indication that presentation of the video content item is to be transferred from the first display device to a different display device; in response to receiving the indication, determining whether the first display device supports transferring the presentation of the video content item and determining whether the different display device is capable of presenting the video content item; and transmitting an indication that presentation of the video content item is to be transferred from the first display device to the different display device, wherein the video content item is played back using the different display device from a playback position that is based on the playback state from the first display device.

Abstract: The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): or pharmaceutically acceptable salts thereof wherein R1, R2, R3, R4, R5, R6, R7, and R8, are as defined herein. The disclosure also relates to methods of making and using compounds of Formula (I) or pharmaceutically acceptable salts thereof.

Abstract: Microbolometer systems and methods are provided herein. For example, an infrared imaging device includes a substrate having contacts and a surface. The surface defines a plane. The infrared imaging device further includes a microbolometer array coupled to the substrate. Each microbolometer of the microbolometer array includes a second having a first dimension that extends in a first direction substantially parallel to the plane and a second dimension that extends in a second direction away from the plane. The first dimension is less than the second dimension. The segment includes a metal layer and a layer formed on a side of the metal layer.

Abstract: Anti-PVRIG and anti-TIGIT antibodies are provided.

Abstract: Provided herein are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, comprising disabling myeloid cells using an anti-Triggering Receptor Expressed on Myeloid Cells 1 (TREM1) antibody.

Abstract: A data processing system comprising a processor having a working memory and processing logic, a boot system configured to load one or more algorithms for initializing a basic input output system (BIOS) of the processor into the working memory and an error correction system configured to start a watchdog timer and to monitor initialization of the processor, the error correction system further configured to implement a corrective process if the watchdog timer times out prior to initialization of the BIOS of the processor.

Abstract: Mechanisms are provided for allowing a user to dynamically manage rich media content in an efficient and effective manner. Tiles including media content, personalized video selections, content pack upgrades, and promotions for featured content are presented to a user. Each tile may include calls to view, purchase, discuss, rate, review, or read about associated content. Tiles may be presented as still images, logos, text, or live video. Multiple tiles may be manipulated using keyboard, mouse, touchpad, and/or touchscreen movements, motions, and gestures. In particular examples, an overlay provided on top of a tile mechanism provides a user with additional navigation and management options.

Abstract: The present invention is directed to anti-PVRIG antibodies and methods of using same.

Abstract: Anti-PVRIG and anti-TIGIT antibodies are provided.

Abstract: Methods, systems, and devices for transitioning an information handling system (IHS) to a predetermined operating state is disclosed. During the transition, the IHS may obtain data from a variety of sources which may subject it to compromise. To reduce the likelihood that the IHS is compromised, the IHS may evaluate its environment and its own operation to determine its security state. Depending on its security state, the IHS may perform various actions to reduce the likelihood of it being compromised through its transition process.

Abstract: The present invention is directed to PVRIG polypeptides and their uses.

Abstract: The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): or pharmaceutically acceptable salts thereof wherein R, R1, R2, R3, R4, R5, R6, R7, and R8, are as defined herein. The disclosure also relates to methods of making and using compounds of Formula (I) or pharmaceutically acceptable salts thereof.

Abstract: A mobile device that includes a camera and an extended reality software application program is employed by a user in an operating environment, such as an industrial environment. One or more objects within a geofence may be identified. A device crosses within the geofence and acquires sensor data associated with an object within the geofence. The sensor data may include image data and/or audio data. The device or a server system may then determine an object identifier associated with the object based on a comparison of the sensor data with data associated with object identifiers corresponding to objects within the geofence. Based on the object identifier, data associated with the object are obtained. The data associated with the object may be presented via the device, such as an extended reality overlay over a view of the object in the device.

Abstract: The present disclosure is directed to systems and methods for securely reflecting data from a local datastore. In one example embodiment, a user may connect local datastores to edge nodes that may facilitate communication between a third-party data management hub and the local datastores. A user operating the third-party data management hub may request to read/write certain data at the local datastores (that the user owns). Data from the local datastore may be generated in response to the request. The responsive data may be transmitted over an encrypted data session to the data management hub, where the responsive data is reflected to the user on a user interface. The responsive data is stored in a volatile memory store and not moved from the persistent memory at the local datastore. Upon termination of the encrypted data session, the volatile memory store is erased to preserve the privacy/security of the underlying data.