Abstract: Disclosed herein are devices comprising one or more cantilevers comprising one or more neuromuscular junctions formed by a co-culture of myotubes and motoneurons. Disclosed herein are methods of using the disclosed devices comprising one or more cantilevers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: In an aspect, disclosed herein are physiological devices and systems, and components thereof, used to evaluate cardiac parameters and arrhythmogenic mechanisms. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Systems, methods, apparatuses, and software for computing systems are provided herein. In one example, a system includes a plurality of first modules each having a Peripheral Component Interconnect Express (PCIe) interface and a processor, and a plurality of second modules each having a PCIe interface. PCIe switch circuitry is coupled to the PCIe interfaces of the first modules and the PCIe interfaces of the second modules, wherein the PCIe switch circuitry is configured to establish logical isolation in the PCIe switch circuitry between one or more first modules and one or more second modules. At least one processor instantiates access to the one or more second modules for the one or more first modules over at least the logical isolation in the PCIe switch circuitry.

Abstract: Systems, methods, apparatuses, and software for data storage systems are provided herein. In one example, a data storage assembly is provided that includes a plurality of storage drives each comprising a PCIe host interface and solid state storage media. The data storage assembly includes a PCIe switch circuit coupled to the PCIe host interfaces of the storage drives and configured to receive storage operations issued by one or more host systems over a shared PCIe interface and transfer the storage operations for delivery to the storage drives over selected ones of the PCIe host interfaces. The data storage assembly includes a control processor configured to monitor usage statistics of the storage drives, and power control circuitry configured to selectively remove the power from ones of the storage drives based at least on the usage statistics of the storage drives.

Abstract: Polycrystalline diamond bodies having an annular region of diamond grains and a core region of diamond grains and methods of making the same are disclosed. In one embodiment, a polycrystalline diamond body (120) includes an annular region (142) of inter-bonded diamond grains having a first characteristic property and a core region (140) of inter-bonded diamond grains bonded to the annular region and having a second characteristic property that differs from the first characteristic property. The annular region decreases in thickness from a perimeter surface of the polycrystalline diamond body towards a centerline axis.

Abstract: Polycrystalline diamond bodies having an annular region of diamond grains and a core region of diamond grains and methods of making the same are disclosed. In one embodiment, a polycrystalline diamond body includes an annular region of inter-bonded diamond grains having a first characteristic property and a core region of inter-bonded diamond grains bonded to the annular region and having a second characteristic property that differs from the first characteristic property. The annular region decreases in thickness from a perimeter surface of the polycrystalline diamond body towards a centerline axis.

Abstract: Disclosed herein are microfluidic systems with recirculation of fluid and computer-implemented methods of calculating conditions within the microfluidic systems. The microfluidic systems include a computing device and a microfluidic device having first and second reservoirs, at least one chamber, and a fluid path connecting the first reservoir, the chamber, and the second reservoir. The methods for calculating conditions include receiving a first reservoir fluid volume, a second reservoir fluid volume, a first concentration, and a second concentration. The methods further include receiving a time-dependent imposed pressure difference between the first reservoir and the second reservoir, then determining a hydraulic pressure difference and an effective pressure difference. The effective pressure difference is used to account for reactions occurring within the microfluidic device and to determine the value of the condition within the microfluidic device.

Abstract: Systems and methods for health monitoring and upgrade of a distributed controller are provided. According to one embodiment of the disclosure, a method for health monitoring and upgrade of a distributed controller may commence with receiving, by a lower level controller from a high-level controller, high-level control references. The method may further include generating low-level control references for a hardware asset based at least in part on the high-level control references. The method may include monitoring the network connection and detecting an error in the network connection. In response to the detection of the error in the network connection, a control of the hardware asset may be transferred to the low-level controller. The method may further include determining that the network connection has been restored. In response to the determination that the network connection has been restored, the control of the hardware asset may be transferred to the high-level controller.

Abstract: A powered orthotic device includes a brace, a finger engagement member, a thumb engagement member, and a hand actuator. The powered orthotic device includes a locking mechanism affixed to the brace, and a finger carrier assembly with a finger carrier to engage the fingers of the wearer, as well as an affixment member configured to be removably attached to the locking mechanism. The wearer dons the orthotic device, without assistance from another, by placing the set of fingers into the finger carrier and using a free hand of the wearer to affix the affixment member to the locking mechanism.

Abstract: Polycrystalline diamond bodies having an annular region of diamond grains and a core region of diamond grains and methods of making the same are disclosed. In one embodiment, a polycrystalline diamond body (120) includes an annular region (142) of inter-bonded diamond grains having a first characteristic property and a core region (140) of inter-bonded diamond grains bonded to the annular region and having a second characteristic property that differs from the first characteristic property. The annular region decreases in thickness from a perimeter surface of the polycrystalline diamond body towards a centerline axis.

Abstract: Systems, methods, apparatuses, and software for data storage systems are provided herein. In one example, a data storage assembly is provided that includes a plurality of storage drives each comprising a PCIe host interface and solid state storage media. The data storage assembly includes a PCIe switch circuit coupled to the PCIe host interfaces of the storage drives and configured to receive storage operations issued by one or more host systems over a shared PCIe interface and transfer the storage operations for delivery to the storage drives over selected ones of the PCIe host interfaces. The data storage assembly includes a control processor configured to monitor usage statistics of the storage drives, and power control circuitry configured to selectively remove the power from ones of the storage drives based at least on the usage statistics of the storage drives.

Abstract: A system including a sump having an inner volume and a junction box coupled to the sump. The junction box has a body defining an inner volume, and also has a first inlet and a second inlet, wherein each inlet is in fluid communication with the inner volume of the body. The junction box further has a first outlet and a second outlet, wherein each outlet is in fluid communication with the inner volume of the body such that a first wire is positionable in the first inlet and the first outlet and a second wire is positioned in the second inlet and the second outlet.

Abstract: Polycrystalline diamond bodies having an annular region of diamond grains and a core region of diamond grains and methods of making the same are disclosed. In one embodiment, a polycrystalline diamond body includes an annular region of inter-bonded diamond grains having a first characteristic property and a core region of inter-bonded diamond grains bonded to the annular region and having a second characteristic property that differs from the first characteristic property. The annular region decreases in thickness from a perimeter surface of the polycrystalline diamond body towards a centerline axis.

Abstract: Systems, methods, apparatuses, and software for data storage systems are provided herein. In one example, a data storage apparatus is provided. The data storage apparatus includes a plurality of storage drives each comprising a drive Peripheral Component Interconnect Express (PCIe) interface. A PCIe switch circuit is coupled to the drive PCIe interfaces of the plurality of storage drives, and the PCIe switch comprises at least two host PCIe interfaces shared among the plurality of storage drives. The PCIe switch circuit is configured to receive storage operations transferred by more than one host system over the at least two host PCIe interfaces, and transfer the storage operations for delivery to selected ones of the plurality of storage drives.

Abstract: Systems, methods, apparatuses, and software for data storage systems are provided herein. In one example, a data storage assembly is provided that includes a plurality of storage drives each comprising a PCIe host interface and solid state storage media. The data storage assembly includes a PCIe switch circuit coupled to the PCIe host interfaces of the storage drives and configured to receive storage operations issued by one or more host systems over a shared PCIe interface and transfer the storage operations for delivery to the storage drives over selected ones of the PCIe host interfaces. The data storage assembly includes a control processor configured to monitor usage statistics of the storage drives, and power control circuitry configured to selectively remove the power from ones of the storage drives based at least on the usage statistics of the storage drives.

Abstract: Polycrystalline diamond bodies having an annular region of diamond grains and a core region of diamond grains and methods of making the same are disclosed. In one embodiment, a polycrystalline diamond body includes an annular region of inter-bonded diamond grains having a first characteristic property and a core region of inter-bonded diamond grains bonded to the annular region and having a second characteristic property that differs from the first characteristic property. The annular region decreases in thickness from a perimeter surface of the polycrystalline diamond body towards a centerline axis.

Abstract: Systems, methods, apparatuses, and software for data storage systems are provided herein. In one example, a data storage assembly is provided. The data storage assembly includes a plurality of storage drives each comprising a PCIe host interface and solid state storage media, with each of the storage drives configured to store and retrieve data responsive to storage operations received over an associated PCIe host interface. The data storage assembly includes a PCIe switch circuit coupled to the PCIe host interfaces of the storage drives and configured to receive the storage operations issued by a plurality of host systems over a shared PCIe interface and transfer the storage operations for delivery to the storage drives over selected ones of the PCIe host interfaces. The data storage assembly includes holdup circuitry configured to provide power to at least the storage drives after input power is lost to the data storage assembly.

Abstract: Cutting elements having accelerated leaching rates and methods of making the same are disclosed herein. In one embodiment, a method of forming a cutting element includes assembling a reaction cell having diamond particles, a non-catalyst material, a catalyst material, and a substrate within a refractory metal container, where the non-catalyst material is generally immiscible in the catalyst material at a sintering temperature and pressure. The method also includes subjecting the reaction cell and its contents to a high pressure high temperature sintering process to form a polycrystalline diamond body that is attached to the substrate. The method further includes contacting at least a portion of the polycrystalline diamond body with a leaching agent to remove catalyst material and non-catalyst material from the diamond body, where a leaching rate of the catalyst material and the non-catalyst material exceeds a conventional leaching rate profile by at least about 30%.

Abstract: A superabrasive material and method of making the superabrasive material are provided. The superabrasive material may comprise a superabrasive crystal having an irregular surface. The superabrasive material further comprises a plurality of structure defects within the superabrasive crystal. The plurality of structure defects may cause micro-chipping when used as grinding materials.