Patents by Inventor Chun-An Kung

Chun-An Kung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190210019
    Abstract: Systems and methods for using microfluidic devices to concentrate cells, to perform buffer changes, to sort cells based on size, and/or to isolate particular types of cells in a rapid manner, are presented. Cells flow into a matrix of posts, wherein the posts are distributed along diagonal lines in the chamber. The cells are deflected in a lateral manner, towards a side of a chamber and are collected upon exiting the chamber.
    Type: Application
    Filed: January 10, 2019
    Publication date: July 11, 2019
    Inventor: Yu-Chun KUNG
  • Patent number: 10252269
    Abstract: Methods and devices are provided for focusing and/or sorting activated T cells. The device comprises a microfluidic channel comprising a plurality of electrodes arranged to provide dielectrophoretic (DEP) forces that are perpendicular to forces from hydrodynamic flows along the channel. The device may be configured to apply voltages to a plurality of electrodes in a first upper region of the microfluidic channel to focus the cells into a single flow, and to apply different voltages to a plurality of electrodes in a second downstream region of the microfluidic channel to sort cells based on size. The output of the microfluidic channel may diverge into multiple channels, wherein cells of various sorted sizes are directed into the appropriate output channel.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: April 9, 2019
    Assignees: NANTBIO, INC., NANOCAV, LLC
    Inventors: Yu-Chun Kung, Ting-Hsiang Wu, Peter Sieling, Kayvan Niazi
  • Publication number: 20190060861
    Abstract: Methods and devices for the formation and/or merging of droplets in microfluidic systems are provided. In certain embodiments a microfluidic droplet merger component is provided that comprises a central channel comprising a plurality of elements disposed and spaced to create a plurality of lateral passages that drain a carrier fluid out of a fluid stream comprising droplets of a first fluid contained in the carrier fluid; and a deformable lateral membrane valve disposed to control the width of said center channel.
    Type: Application
    Filed: August 28, 2018
    Publication date: February 28, 2019
    Inventors: Yu-Chun Kung, Pei-Yu E. Chiou, Ting-Hsiang S. Wu, Yue Chen, Michael A. Teitell
  • Patent number: 10071359
    Abstract: Methods and devices for the formation and/or merging of droplets in microfluidic systems are provided. In certain embodiments a microfluidic droplet merger component is provided that comprises a central channel comprising a plurality of elements disposed and spaced to create a plurality of lateral passages that drain a carrier fluid out of a fluid stream comprising droplets of a first fluid contained in the carrier fluid; and a deformable lateral membrane valve disposed to control the width of said center channel.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 11, 2018
    Assignee: The Regents of the University of California
    Inventors: Yu-Chun Kung, Pei-Yu E. Chiou, Ting-Hsiang S. Wu, Yue Chen, Michael A. Teitell
  • Publication number: 20180141048
    Abstract: Methods and devices are provided for focusing and/or sorting activated T cells. The device comprises a microfluidic channel comprising a plurality of electrodes arranged to provide dielectrophoretic (DEP) forces that are perpendicular to forces from hydrodynamic flows along the channel. The device may be configured to apply voltages to a plurality of electrodes in a first upper region of the microfluidic channel to focus the cells into a single flow, and to apply different voltages to a plurality of electrodes in a second downstream region of the microfluidic channel to sort cells based on size. The output of the microfluidic channel may diverge into multiple channels, wherein cells of various sorted sizes are directed into the appropriate output channel.
    Type: Application
    Filed: November 17, 2017
    Publication date: May 24, 2018
    Inventors: Yu-Chun KUNG, Ting-Hsiang WU, Peter SIELING, Kayvan NIAZI
  • Publication number: 20180029044
    Abstract: A 3-dimensional PDMS cell sorter having multiple passages in a PDMS layer that follow the same path in a DEP separation region and that are in fluid communication with each other within that region. The passages may differ in width transverse to the flow direction within the passages. Flat plates may sandwich the PDMS layer; each plate may have a planar electrode used to generate a DEP field within a sample fluid flowed within the passages. The DEP field may concentrate target cells or particulates within one of the passages within the DEP separation region. The passages may diverge after the DEP-separation region, leaving one passage with a high concentration of target cells or particulates. Techniques for manufacturing such structures, as well as other micro-fluidic structures, are also provided.
    Type: Application
    Filed: September 25, 2017
    Publication date: February 1, 2018
    Inventors: Pei-Yu E. Chiou, Kuo-Wei Huang, Yu-Jui Fan, Yu-Chun Kung
  • Publication number: 20170291172
    Abstract: In various embodiments methods and devices are provided for focusing and/or sorting particles and/or cells in a microfluidic channel. In certain embodiments the device comprises a microfluidic channel comprising a plurality of electrodes disposed to provide dielectrophoretic (DEP) forces that are perpendicular to hydrodynamic flows along the channel; wherein said device is configured to apply voltages to said electrodes to provide an electric field minimum that is not centered in said microfluidic channel.
    Type: Application
    Filed: April 11, 2017
    Publication date: October 12, 2017
    Inventors: YU-CHUN KUNG, PEI-YU E. CHIOU
  • Patent number: 9770721
    Abstract: A 3-dimensional PDMS cell sorter having multiple passages in a PDMS layer that follow the same path in a DEP separation region and that are in fluid communication with each other within that region. The passages may differ in width transverse to the flow direction within the passages. Flat plates may sandwich the PDMS layer; each plate may have a planar electrode used to generate a DEP field within a sample fluid flowed within the passages. The DEP field may concentrate target cells or particulates within one of the passages within the DEP separation region. The passages may diverge after the DEP-separation region, leaving one passage with a high concentration of target cells or particulates. Techniques for manufacturing such structures, as well as other micro-fluidic structures, are also provided.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: September 26, 2017
    Assignee: The Regents of the University of California
    Inventors: Pei-yu E. Chiou, Kuo-wei Huang, Yu-jui Fan, Yu-chun Kung
  • Publication number: 20170234895
    Abstract: What is described is a kit for preparing a liquid thromboplastin reagent for a prothrombin time assay. The kit simplifies and minimizes reagent preparation time and is stable for 2-5 years.
    Type: Application
    Filed: February 10, 2017
    Publication date: August 17, 2017
    Inventors: Kevin M Cawthern, Ralph E. Bottenus, Chun Kung
  • Publication number: 20160363125
    Abstract: An outer rotor type fan structure includes a stator assembly, an outer rotor assembly, a front lateral shielding sheet and an impeller. The stator assembly includes a stator core and a plurality of coils. The outer rotor assembly corresponds to and covers the stator assembly. The outer rotor assembly includes a plurality of magnets and a rotor yoke. The plurality of magnets is disposed corresponding to the plurality of coils. The front lateral shielding sheet is a metallic sheet, the front lateral shielding sheet is disposed between the stator assembly and the outer rotor assembly, and the front lateral shielding sheet corresponds to and covers the plurality of coils. The impeller includes a plurality of blades. The rotor yoke drives the plurality of blades rotating. Thereby, the outer rotor type fan structure can be shielded and the fan can operate properly.
    Type: Application
    Filed: August 25, 2015
    Publication date: December 15, 2016
    Inventors: Han-En CHIEN, Hung-Chi CHEN, Meng-Yu CHEN, Che-Hung LIN, Chao-Chun KUNG
  • Publication number: 20160051958
    Abstract: Methods and devices for the formation and/or merging of droplets in microfluidic systems are provided. In certain embodiments a microfluidic droplet merger component is provided that comprises a central channel comprising a plurality of elements disposed and spaced to create a plurality of lateral passages that drain a carrier fluid out of a fluid stream comprising droplets of a first fluid contained in the carrier fluid; and a deformable lateral membrane valve disposed to control the width of said center channel.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 25, 2016
    Inventors: Yu-Chun KUNG, Pei-Yu E. CHIOU, Ting-Hsiang S. WU, Yue Chen, Michael A. Teitell
  • Publication number: 20150041325
    Abstract: A 3-dimensional PDMS cell sorter having multiple passages in a PDMS layer that follow the same path in a DEP separation region and that are in fluid communication with each other within that region. The passages may differ in width transverse to the flow direction within the passages. Flat plates may sandwich the PDMS layer; each plate may have a planar electrode used to generate a DEP field within a sample fluid flowed within the passages. The DEP field may concentrate target cells or particulates within one of the passages within the DEP separation region. The passages may diverge after the DEP-separation region, leaving one passage with a high concentration of target cells or particulates. Techniques for manufacturing such structures, as well as other micro-fluidic structures, are also provided.
    Type: Application
    Filed: March 27, 2013
    Publication date: February 12, 2015
    Inventors: Pei-yu E. Chiou, Kuo-wei Huang, Yu-jui Fan, Yu-chun Kung
  • Patent number: 7819696
    Abstract: A shielded connector (1) for electrically connecting a camera module to a printed circuit board at least comprises a metal housing (10) configured by a base and four sidewalls and a spring (20) against with the base of the housing. And one of the sidewall includes a fixed portion and a flexible portion. Said flexible portion defines a latchable portion against with the camera module, which extends from an adjacent sidewall to said sidewall towards the opposite sidewall to said adjacent sidewall. Therefore, the elastic of the flexible portion is improved and a better electrical connection is provided between the camera module and a circuit board.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: October 26, 2010
    Assignee: Hon Hai Precision Ind. Co., Ltd
    Inventor: Chun-Kung Wu
  • Patent number: 7723014
    Abstract: A method for photolithography in semiconductor manufacturing includes providing a substrate for a wafer and providing a mask for exposing the wafer. The wafer is exposed by utilizing a combination of high angle illumination and focus drift exposure methods.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: May 25, 2010
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Kuei Shun Chen, Chin-Hsiang Lin, Tsai-Cheng Gau, Chun-Kung Chen, Hsiao-Tzu Lu, Fu-Jye Liang
  • Patent number: 7699661
    Abstract: An electrical card connector for receiving a card comprises an insulating housing with a plurality of contacts, a cover, and a pivoting mechanism moveably connecting the cover and the housing. A pair pivoting portions is disposed on the opposite sides of a rear end of the cover, and a pair of mounting portions is disposed on an end of the housing corresponding to the pivoting portions. The connector further comprises an enforcing member having a pair of pivoting wings mounted to the mounting portions of the housing, and each pivoting wing has a pivoting hole for moveably connecting the pivoting portion of the cover. The pivoting wing of the enforcing member and the pivoting portion of the cover together form the pivoting mechanism.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: April 20, 2010
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventor: Chun-Kung Wu
  • Patent number: 7578677
    Abstract: A shielded shell (1) for interconnecting a camera module to a printed circuit board via a flexible printed circuit board comprises a base wall and a frond wall, a back wall, a left wall and a right wall cooperatively defining a receiving space. A plurality of spring fingers is integrally formed on one of the bottom wall and sidewalls. Therefore, the procedure is simply and a better electrical path is provided between the camera module and the printed circuit board.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: August 25, 2009
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventor: Chun-Kung Wu
  • Patent number: 7578688
    Abstract: An electrical connector for connecting a flexible printed circuit, comprising: a housing comprising a base portion and a mating portion extending forwardly from the base portion; a plurality of electrical contacts received in the housing; and an actuator pivotally mounted to the housing for rotating movement between an opened position and a closed position, the actuator comprising a flat member, a pair of supporting mechanism each integrally formed on opposite ends of the flat member, and an arrangement provided adjacent to the supporting mechanism limiting pivotal movement of the actuator when the actuator in the opened position.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: August 25, 2009
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventor: Chun-Kung Wu
  • Publication number: 20090180278
    Abstract: A safety helmet includes a helmet body, a solar panel on the surface of the helmet body, a headlight at the front side of the helmet body, a warning signal light at the rear side of the helmet body, a control circuit and a rechargeable battery on the inside of the helmet body, and a switch on the outside of the helmet body. When the switch is off, electric energy generated by the solar panel is stored in the rechargeable battery subject to the control of the control circuit; when the switch is on, the loop of the control circuit and the headlight and the warning signal light is closed, causing the headlight to emit light for illumination and the warning signal light to flash for giving a visual warning signal to vehicles from behind to assure safety when riding a bicycle or working at night.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 16, 2009
    Inventors: Chun Kung Cheng, Wen Tsung Kuo, Chang Fong Liou
  • Patent number: 7501226
    Abstract: An immersion lithography system is disclosed to comprise a fluid containing feature for providing an immersion fluid for performing immersion lithography on a wafer, and a seal ring covering a predetermined portion of a wafer edge for preventing the immersion fluid from leaking through the covered portion of the wafer edge while the fluid is used for the immersion lithography.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: March 10, 2009
    Assignee: Taiwan Semiconductor Manufacturing Co., Ltd.
    Inventors: Burn Jeng Lin, Tsai-Sheng Gau, Chun-Kung Chen, Ru-Gun Liu, Shing Shen Yu, Jen Chieh Shih
  • Patent number: D589885
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: April 7, 2009
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventor: Chun-Kung Wu