Publication number: 20230391811
Abstract: A compound comprising a first ligand LA of Formula I, where at least one RA or RB substituent has a structure according to Formula II, is provided. In Formula I and Formula II, moieties A, B, and C are independently rings or a fused-ring systems; each of X1, X2, Z1, Z2, X3, and Z4 is C or N; K a direct bond or selected from the group consisting of O, S, N(R?), P(R?), B(R?), C(R?)(R?), and Si(R?)(R?); L is a linker; n is 1, 2, or 3; each R, R?, R?, R?, RA, RB, RC, RL, and RL? is independently hydrogen or a General Substituent; and at least one R or R? is a fully or partially fluorinated alkyl group, a fully or partially fluorinated cycloalkyl group, a cyano group, a cyanoalkyl group, or a silyl group. Formulations, OLEDs, and consumer products containing the compound are also provided.
Type:
Application
Filed:
May 19, 2023
Publication date:
December 7, 2023
Applicant:
Universal Display Corporation
Inventors:
Zhiqiang JI, Derek Ian WOZNIAK, Chun LIN
Patent number: 11833223
Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to stage-specific embryonic antigen 4 (SSEA-4) are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as breast cancer, lung cancer, esophageal cancer, rectal cancer, biliary cancer, liver cancer, buccal cancer, gastric cancer, colon cancer, nasopharyngeal cancer, kidney cancer, prostate cancer, ovarian cancer, cervical cancer, endometrial cancer, pancreatic cancer, testicular cancer, bladder cancer, head and neck cancer, oral cancer, neuroendocrine cancer, adrenal cancer, thyroid cancer, bone cancer, skin cancer, basal cell carcinoma, squamous cell carcinoma, melanoma, and/or brain tumor.
Type:
Grant
Filed:
January 27, 2021
Date of Patent:
December 5, 2023
Assignee:
OBI PHARMA, INC.
Inventors:
Cheng-Der Tony Yu, Jiann-Shiun Lai, I-Ju Chen, Chiu-Chun Lin