Abstract: A method for fabricating semiconductor device is disclosed. The method includes the steps of: providing a substrate having a gate structure thereon; forming a first cap layer on a surface of the substrate and sidewall of the gate structure; forming a second cap layer on the first cap layer; forming a third cap layer on the second cap layer; performing an etching process to partially remove the third cap layer, the second cap layer, and the first cap layer to form a first spacer and a second spacer on the sidewall of the gate structure; and forming a contact etch stop layer (CESL) on the substrate to cover the second spacer, wherein the third cap layer and the CESL comprise same deposition condition.

Abstract: Provided is a semiconductor image sensor device that includes a non-scribe-line region and a scribe-line region. The image sensor device includes a first substrate portion disposed in the non-scribe-line region. The first substrate portion contains a doped radiation-sensing region. The image sensor device includes a second substrate portion disposed in the scribe-line region. The second substrate portion has the same material composition as the first substrate portion. Also provided is a method of fabricating an image sensor device. The method includes forming a plurality of radiation-sensing regions in a substrate. The radiation-sensing regions are formed in a non-scribe-line region of the image sensor device. The method includes forming an opening in a scribe-line region of the image sensor device by etching the substrate in the scribe-line region. A portion of the substrate remains in the scribe-line region after the etching. The method includes filling the opening with an organic material.

Abstract: A manufacturing method of a semiconductor device having metal gate includes providing a substrate having a first semiconductor device, a second semiconductor device, and a first insulating layer covering the first semiconductor device and the second semiconductor device formed thereon, performing an etching process to remove a portion of the first insulating layer to expose a portion of the first semiconductor device and the second semiconductor device, forming a second insulating layer covering the first semiconductor device and the second semiconductor device, performing a first planarization process to remove a portion of the second insulating layer, forming a first gate trench and a second gate trench respectively in the first semiconductor device and the second semiconductor device, and forming a first metal gate and a second metal gate respectively in the first gate trench and the second gate trench.

Abstract: A method for fabricating semiconductor device is disclosed. The method includes the steps of: providing a substrate having a gate structure thereon; forming a first cap layer on a surface of the substrate and sidewall of the gate structure; forming a second cap layer on the first cap layer; forming a third cap layer on the second cap layer; performing an etching process to partially remove the third cap layer, the second cap layer, and the first cap layer to form a first spacer and a second spacer on the sidewall of the gate structure; and forming a contact etch stop layer (CESL) on the substrate to cover the second spacer, wherein the third cap layer and the CESL comprise same deposition condition.

Abstract: A manufacturing method of a semiconductor device includes the following steps. First, a substrate is provided. At least one sacrificial gate structure is formed on the substrate, at least one diffusion region is formed in the substrate at each of two sides of the sacrificial gate structure, and a first inter-layer dielectric layer is formed to cover the diffusion region. A gate recess is then formed in the sacrificial gate structure. A first diffusion contact hole is then formed in the first inter-layer dielectric layer and at least partially exposes the diffusion region. A metal layer is subsequently formed in the gate recess and the first diffusion contact hole.

Abstract: The present invention discloses a pharmaceutical composition for inhibiting histone H4 and a manufacturing method thereof. The pharmaceutical composition comprises an anti-histone H4 antibody and a pharmaceutically acceptable excipient. The hair loss resulted from medications, including cancer drugs, can be reduced by using the pharmaceutical composition of the present invention, thereby resolving mental depression and promoting prognosis effects for patients.

Abstract: The present invention discloses a sensor chip for screening a topoisomerase inhibitor and a screening method thereof. The sensor chip comprises topoisomerase I and a biochip. The topoisomerase I is immobilized on the biochip, and the topoisomerase I has DNA catalytic activity. This provides a rapid screening method for topoisomerase I inhibitors.

Abstract: The present invention relates to a surface chemically modified organic high polymer nanometer powder and its preparation method. The phosphoric acid modified nanometer powdery material of the present invention is polyether polyurethane or polyester polyurethane nanometer powder. The surface of the powder has self-assembled phosphate groups. It is prepared by the following method: phosphate groups are introduced into polyether polyurethane or polyester polyurethane nanometer powder in a phosphoric acid buffer solution by means of physical adsorption. This method can improve the stability and dispersibility of the powder and change its physical, chemical and biological properties and hopefully will realize intensive and extensive application in biomedical field. The surface modified nanometer powder of the present invention is in a controllable size of 50 nm˜500 nm and its surface Zeta potential in physiological environment is negative.

Abstract: The invention relates to the compounds isolated from Evodia rutaecarpa (Juss.), in that has been demonstrated to inhibit topoisomerase I. Evodiamine, an alkaloidal compound is reported the topoisomerase I inhibitory activity. The effect of evodiamine acts by stabilizing the covalent complex between topoisomerase I and DNA, which results in a blockade of DNA replication and transcription.

Abstract: Binoculars having a center-focusing function and an individual-focusing comprise a telescopic base provided at an end thereof with a control sleeve which is connected to a left lens system in a left barrel and a right lens system in a right barrel through an adjusting portion disposed in the telescopic base. When a user pushes the control sleeve so that the control sleeve is forced to shift toward the adjusting portion, the user can rotate the control sleeve to simultaneously actuate the adjusting portion, so as to adjust focuses of the left and right lens systems. When the user pulls the control sleeve so that the control sleeve is forced to shift away from the adjusting portion, the user can rotate the control sleeve to simultaneously actuate the adjusting portion, so as to adjust a parallax between one and the other of the left and right lens systems.

Abstract: In a binocular telescope with an adjustable prism module, an eyepiece lens module, a prism module and an objective lens module are installed inside a telescope tube of the binocular telescope. The prism module includes a prism base, a first right-angle prism, a Porro prism, a second right-angle prism and a support base, and an exit surface of the first right-angle prism is connected with an incident surface of the Porro prism, and the second right-angle prism is set on the support base, and the incident surface of the second right-angle prism is attached to the Porro prism. The first and second right-angle prisms can be adjusted to change the angle of optical axes among the prism module, the eyepiece lens module and the objective lens module to prevent a distortion of the optical imaging.

Abstract: A waterproof zoom binocular telescope includes a left lens barrel, a right lens barrel, an ocular base disposed at an end of each lens barrel, and a synchronous belt sprocket disposed at the connecting position of the two ocular bases. Each ocular base includes an ocular module, and the two ocular modules separately include a zoom unit. Each zoom unit and the synchronous belt sprocket are connected with a synchronous belt to form a transmission chain structure. An eccentric cam is installed between two external common tangents of each ocular module and the synchronous belt sprocket for tightly pressing the two synchronous belts. If any one of the zoom units rotates, the transmission chain structure effectively drives the synchronous belt to rotate another zoom unit correspondingly.

Abstract: A light reflector is mounted to a personal item, such as shoe, clothes, and hats. The light reflector includes a light reflective base plate having a surface on which at least one light reflecting cone is formed for reflecting light incident onto the reflector. The light reflector has a light non-transmitting layer formed on a surface thereof except the portion where light transmits into the light reflector. The light non-transmitting layer prevents the reflected light from being randomly dispersed. The cones may be formed of a plurality of flat faces having different angular orientations whereby light is reflected in such a way to provide shining and glaring effect.

Abstract: A novel Ultra-trace Automatic Mercury Species Analyzer (AMSA) is a semi-automatic or automatic on-line dual-channel detection device. The principle of the methodology is on-line coupling of analytical stages (or set-ups) with cold vapor atomic detector using flow injection analysis technique. This analyzer can be fully automatic for fast and accurate monitoring Hg species of natural environmental samples in ultra-trace levels. Furthermore, the AMSA is well suitably used in laboratory or other field stations (e.g., shipboard uses etc.) It provides ease of operation, fast analysis, high analytical performance, and excellent data quality. There is no risk of contamination with ambient air and no need of ultra-clean class-100 room to obtain the high quality data on ultra-trace mercury species analyses (e.g., Hg0, Hg2+, monomethyl Hg, dimethyl Hg etc.) in natural environmental samples (e.g., air, water, sediment, soil, vegetation, bio-tissues and other sample types).

Abstract: A binocular is constructed to include a bridge, the bridge having two rows of knuckles aligned at two opposite lateral sides thereof, two bodies respectively pivoted to the bridge at two sides, the bodies each having a row of knuckles respectively coupled to the knuckles of the bridge, and two pivot bolts respectively fastened to the knuckles of the bridge and the knuckles of the bodies to couple the bodies to the bridge, for enabling the bodies to be turned relative to the bridge to the desired angle.

Abstract: A disc wheel cover comprising a side ring joiner and a disc wheel side ring having free ends joined by the joiner. The joiner has two pairs of holes having different depths for the ends of the side ring to be selectably inserted and retained therein so that the side ring diameter can be varied to match the wheel despite any small error in the wheel diameter.

Abstract: A portable camera support assembly having an adjustment block, a support piece, a shoulder rest, a camera mount, a lengthwise-extendible hand grip, a body rest, a mount adjustment knob and a torsional spring assembly. The support assembly fixes to a lower end of a camera using the camera mount. The shoulder rest and body rest are used to support and balance the camera at the shoulder and upper body of the user respectively. The adjustment block, hand grip and mount adjustment knob allow the user to position the camera in a wide range of orientations during use and also allow the support assembly to be folded up when not in use. Additionally, the hand grip and body rest can be removed and a retractable monopole fixed to the adjustment block for support of the camera remote from the user.