Abstract: Provided herein are methods for producing neuroectoderm and retinal progenitor cells from pluripotent stem cells, and compositions of retinal progenitor cells produced thereby.

Abstract: A double image projection lamp has a housing, a first and a second projecting assembly in the housing, a driver, a light shielding element, and a driven component. The second projecting assembly has a shell body pivotally connected to the housing, connected to the driver, and having a sliding groove between a projecting end of the shell body and a light emitting unit of the second projecting assembly. The light shielding element is disposed in the sliding groove. When the driver drives the shell body to pivot, the driven component is driven by the shell body and drives the light shielding element to move along the sliding groove so as to allow light emitted from the light emitting unit to be shielded by the shielding element or travel to the projecting end, which provides fade-in and fade-out visual effects when two projected images move relatively.

Abstract: The present disclosure relates to the preparation of synthetic cannabinoid derivatives of Formulae I and II, and compositions made therefrom.

Abstract: A vehicle charging system comprises at least one controller and at least one arm, each arm having a first end coupled to an actuator and a second end comprising a charging interface. The actuator is configured to articulate the arm into a charging position. The charging interface comprises at least one charging contact coupled to a power source and configured to engage and deliver power to a vehicle charging interface to charge at least one battery of a vehicle. The charging system can include a plurality of arms, each configured to charge a different vehicle. A method of charging one or more vehicles using the charging system is also provided.

Abstract: The present invention discloses a highly integrated R-wave triggered tumor therapy apparatus, and relates to the technical field of medical devices for ablation of tumors. The apparatus includes: a human body R-wave detection module for detecting a human body R-wave signal; a signal generator for obtaining a narrow pulse signal with nanometer width according to the human body R-wave signal; a primary matching circuit; and a high-frequency transformer; where the primary matching circuit is used for matching the narrow pulse signal with nanometer width to an input side of the high-frequency transformer, so that the high-frequency transformer outputs a high-voltage signal needed for treatment of human bodies.

Abstract: Methods and compositions relating to motor neurons derived from induced pluripotent stem cells of subjects having a neurodegenerative disease, where the motor neurons exhibit phenotypes characteristic of the neurodegenerative disease, are provided herein. In particular, the present invention provides methods for screening putative therapeutic agents and methods for diagnosing living subjects as having a neurodegenerative disease. In addition, the present invention provides therapeutic gene transfer methods for treating or preventing a neurodegenerative disease in a subject in need thereof.

Abstract: Control set optimization for a circuit design includes generating, by a processor, Observability Don't Care (ODC) expressions for registers of the circuit design. Redundant reset pins of the registers of the circuit design are determined by the processor by iteratively checking, on a per-cube and a per-literal basis for each ODC expression, whether a value of a literal causes the ODC expression to evaluate to 1. A modified version of the circuit design is generated by the processor by connecting one or more reset pins of the set of redundant reset pins to one or more constants.

Abstract: A transport vehicle, such as a vision guided vehicle, can comprise a drive portion constructed to facilitate movement of the transport vehicle and a load portion constructed to engage an object of interest. The load portion can comprise an object engagement apparatus and at least one sensor coupled to or disposed within a distal end of the object engagement apparatus, wherein the sensor can be at least a 2D sensor. The engagement apparatus can comprise forks, at least one fork having sensor coupled to or disposed within a fork tip. The 2D sensor can comprise a scanning LIDAR sensor arranged to collect information to identify a pickable pallet, for example.

Abstract: A vehicle charging system comprises at least one controller and at least one arm, each arm having a first end coupled to an actuator and a second end comprising a charging interface. The actuator is configured to articulate the arm into a charging position. The charging interface comprises at least one charging contact coupled to a power source and configured to engage and deliver power to a vehicle charging interface to charge at least one battery of a vehicle. The charging system can include a plurality of arms, each configured to charge a different vehicle. A method of charging one or more vehicles using the charging system is also provided.

Abstract: A chuck for gripping a workpiece includes: a chuck body; a jaw connected to the chuck body for constrained movement relative to the chuck body along a jaw path in jaw-closing and jaw-opening directions; an actuator body connected to the chuck body for constrained movement relative to the chuck body along an actuator path; and a slider body connected to the chuck body for constrained movement relative to the chuck body along a slider body path. The slider body is connected to the jaw for constrained movement relative to the jaw along a slider-body-to-jaw path. The slider body is connected to the actuator body for constrained movement relative to the actuator body along a slider-body-to-actuator-body path.

Abstract: The present disclosure provides an optimal current selection method for a hybrid parallel integrated power supply, including the following steps: selecting multiple power device combinations with different current ratios, the combinations being formed by silicon insulated-gate bipolar transistor (Si IGBT) and silicon carbide metal-oxide-semiconductor field-effect transistor (SiC MOSFET) devices; comparing cost and junction temperatures on the Si IGBT devices and the SiC MOSFET devices under the different current ratios; comparing efficiency of a hybrid parallel integrated power supply with the different current ratios under different SiC MOSFET switching frequencies; comparing electromagnetic interference (EMI) noise of the hybrid parallel integrated power supply; selecting an optimal current ratio for the hybrid parallel integrated power supply.

Abstract: Disclosed is a control method for a hybrid parallel integrated power supply. Under the condition of a 2:1 current ratio between a Si-based inverter and a SiC-based inverter, an optimal power ratio between the two inverters is obtained by reducing a power loss of a fundamental wave component on the Si-based inverter. Based on the fitting for effective values of a harmonic current on the Si-based inverter, an optimal switching frequency of the Si-based inverter and a relationship between a minimum harmonic-current conduction loss and a switching loss under the optimal switching frequency are obtained. Zero sequence components of the current are eliminated through rapid switching of the SiC-based inverter, to suppress harmonic waves.

Abstract: Disclosed are an actuator for hip replacement and a surgical system. The actuator for the hip replacement is configured to prepare a space for installing a prosthesis on a bone and implanting the prosthesis, which includes a first actuator and a second actuator. The first actuator is configured to connect a cutting tool to process an acetabulum and/or a medullary cavity, and the first actuator has a first connector and a second connector. The second actuator is configured to connect to the second connector of the first actuator during an operation of implantation of the prosthesis is performed, and connect the prosthesis and receive impact produced during installing the prosthesis. The actuator for the hip replacement is configured to be installed to a robotic arm via the first connector.

Abstract: A transport vehicle, such as a vision guided vehicle, can comprise a drive portion constructed to facilitate movement of the transport vehicle and a load portion constructed to engage an object of interest. The load portion can comprise an object engagement apparatus and at least one sensor coupled to or disposed within a distal end of the object engagement apparatus, wherein the sensor can be at least a 2D sensor. The engagement apparatus can comprise forks, at least one fork having sensor coupled to or disposed within a fork tip. The 2D sensor can comprise a scanning LIDAR sensor arranged to collect information to identify a pickable pallet, for example.

Abstract: A vehicle mountable system for deploying and retrieving traffic barriers to and from a plurality of locations on a road, the system comprising: a gantry frame assembly with one or more horizontal frame members adapted to be positioned on a tray of a vehicle, a first transfer assembly movably coupled with the gantry frame for transferring one or more traffic barriers positioned on the vehicle tray between a storage location on the tray of the vehicle and an intermediate holding location on a platform assembly located below the one or more horizontal frame members of gantry frame assembly, and a second transfer assembly for transfer of the barriers between the intermediate holding location on the platform and a deployment location on the road.

Abstract: The disclosure relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof wherein A, Ra to Rd, and R4 to R7, are as described herein, as well as compositions and methods of using such compounds.

Abstract: The disclosure relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof wherein A, Ra to Rd, and R4 to R7, are as described herein, as well as compositions and methods of using such compounds.

Abstract: A vehicle charging system comprises at least one controller and at least one arm, each arm having a first end coupled to an actuator and a second end comprising a charging interface. The actuator is configured to articulate the arm into a charging position. The charging interface comprises at least one charging contact coupled to a power source and configured to engage and deliver power to a vehicle charging interface to charge at least one battery of a vehicle. The charging system can include a plurality of arms, each configured to charge a different vehicle. A method of charging one or more vehicles using the charging system is also provided.

Abstract: Disclosed herein are impedance-based biosensor systems comprising an impedance-based biosensor having an electrode, a meter in electrical communication with the electrode, a processor in electrical communication with the impedance-based biosensor and the meter, and a memory storing instructions to be executed by the processor. The instructions can cause the impedance-based biosensor system to measure the impedance of the electrode, derive one or more electrical properties of the impedance-based biosensor from the impedance of the electrode, and calculate a viable cell count based on the one or more electrical properties.

Abstract: Implementing circuit designs in integrated circuit devices includes determining, using computer hardware, regular control sets, super control sets, and mega control sets for a circuit design. Control set optimization is performed on the circuit design. Performing control set optimization includes performing a clock-enable-only control set reduction for each super control set. Performing control set optimization includes performing a set/reset control set reduction and a clock-enable control set reduction for each mega control set. The circuit design is selectively modified by committing changes determined from the control set reductions to the circuit design on a per control set basis based on an improvement of a cost metric for each control set.