Abstract: Systems and methods are disclosed herein for monitoring health of each switch of a plurality of switches on a network by selectively mirroring packets transmitted by each switch of the plurality of switches. In some embodiments, control circuitry generates a plurality of mirroring parameters, each mirroring parameter comprising an instruction to mirror a respective type of packet. The control circuitry transmits the plurality of mirroring parameters to each switch of the plurality of switches on the network, and receives, from a switch, a packet that was mirrored by the switch according to a mirroring parameter of the plurality of mirroring parameters. The control circuitry determines the respective type of the packet, executes an analysis of contents of the packet based on the respective type of the packet, and determines a health of the switch based on results of the analysis.

Abstract: Methods and compositions relating to motor neurons derived from induced pluripotent stem cells of subjects having a neurodegenerative disease, where the motor neurons exhibit phenotypes characteristic of the neurodegenerative disease, are provided herein. In particular, the present invention provides methods for screening putative therapeutic agents and methods for diagnosing living subjects as having a neurodegenerative disease. In addition, the present invention provides therapeutic gene transfer methods for treating or preventing a neurodegenerative disease in a subject in need thereof.

Abstract: A wall lamp has a lamp housing having multiple decorative holes, a front decorative plate, an LED lighting assembly, and a rotating driver. The LED lighting assembly is disposed in the lamp housing and has multiple LED components. The rotating driver is mounted in the lamp housing and is connected to the LED lighting assembly. The LED lighting assembly driven by the rotating driver is rotated to change projecting positions of the LED components relative to the decorative holes of the lamp housing for generating a dynamic lighting effect that resembles peacock feather spreading and increasing dynamic variations of a decorative effect of the wall lamp.

Abstract: Systems and methods are disclosed herein for monitoring health of each switch of a plurality of switches on a network by selectively mirroring packets transmitted by each switch of the plurality of switches. In some embodiments, control circuitry generates a plurality of mirroring parameters, each mirroring parameter comprising an instruction to mirror a respective type of packet. The control circuitry transmits the plurality of mirroring parameters to each switch of the plurality of switches on the network, and receives, from a switch, a packet that was mirrored by the switch according to a mirroring parameter of the plurality of mirroring parameters. The control circuitry determines the respective type of the packet, executes an analysis of contents of the packet based on the respective type of the packet, and determines a health of the switch based on results of the analysis.

Abstract: A plug has a seat, a circuit board disposed in the seat, and a waterproof terminal connector disposed on the seat. The waterproof terminal connector has two terminals and a cover. Each one of the terminals has a tube portion, a division plate, and a connecting portion. The tube portion has a chamber formed in the tube portion. The division plate is formed in the tube portion for dividing the chamber of the tube portion into a first space and a second space. The connecting portion is formed on the tube portion. The cover is formed by an overmolding process, is connected to the two terminals and fills the second spaces of the two terminals. Water vapor can be stopped by the division plate for improving the waterproof effect of the plug.

Abstract: Provided herein are methods and compositions for inducing chemical senescence in neurons and methods of using chemically induced senescent neurons for modeling neurodegenerative disease and drug discovery. The methods include contacting human neurons with a culture medium comprising an inhibitor of DNA glycosylase 1, an autophagy inhibitor, and an HIV protease inhibitor to obtain an in vitro population of senescent neurons within about 4 days. When the neurons are obtained from a patient having a neurodegenerative disease, chemically induced senescent neurons obtained by these methods recapitulate cellular and subcellular phenotypes observed in individuals with the neurodegenerative disease.

Abstract: The present disclosure relates to the preparation of methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate (ITE) and related compounds with high yield, purity, and scalability. The processes apply the use of a Weinreb amide intermediate as a scaffold for the preparation of ITE and structural analogs.

Abstract: Systems and methods for culturing cells are disclosed. A system can comprise an auxetic scaffold substrate. The substrate can comprise scaffold units at least a portion of which comprise living cells. Scaffold units can be configured to transition between a contracted state and an expanded state. Units can comprise an interior void having a contracted volume in the contracted state and an expanded volume in the expanded state, in which the expanded volume is greater than the contracted volume. Units can be configured to pass a fluid into the interior void of the corresponding unit when the unit transitions from the contracted state to the expanded state. Units can be configured to pass the fluid out of the interior void of the corresponding unit when the unit transitions from the expanded state to the contracted state.

Abstract: A vehicle charging system comprises at least one controller and at least one arm, each arm having a first end coupled an actuator and a second end comprising a charging interface. The actuator is configured to articulate the arm into a charging position. The charging interface comprises at least one charging contact coupled to a power source and configured to engage and deliver power to a vehicle charging interface to charge at least one battery of a vehicle. The charging system can include a plurality of arms, each configured to charge a different vehicle. A method of charging one or more vehicles using the charging system is also provided.

Abstract: Methods and compositions for expanding dopaminergic neuron progenitor cells are described herein that include use of compositions and culture media that have at least the following components: an FGF, an agonist of SHH signaling, an agonist of canonical Wnt signaling, and Wnt-C59. The methods include contacting dopaminergic neuron progenitor cells with a culture medium comprising an FGF, an agonist of SHH signaling, an agonist of canonical Wnt signaling, and Wnt-C59, to generate an expanded dopaminergic neuron progenitor cell population.

Abstract: A plug has a seat, a circuit board disposed in the seat, and a waterproof terminal connector disposed on the seat. The waterproof terminal connector has two terminals and a cover. Each one of the terminals has a tube portion, a division plate, and a connecting portion. The tube portion has a chamber formed in the tube portion. The division plate is formed in the tube portion for dividing the chamber of the tube portion into a first space and a second space. The connecting portion is formed on the tube portion. The cover is formed by an overmolding process, is connected to the two terminals and fills the second spaces of the two terminals. Water vapor can be stopped the division plate for improving the waterproof effect of the plug.

Abstract: Methods and compositions relating to motor neurons derived from induced pluripotent stem cells of subjects having a neurodegenerative disease, where the motor neurons exhibit phenotypes characteristic of the neurodegenerative disease, are provided herein. In particular, the present invention provides methods for screening putative therapeutic agents and methods for diagnosing living subjects as having a neurodegenerative disease. In addition, the present invention provides therapeutic gene transfer methods for treating or preventing a neurodegenerative disease in a subject in need thereof.

Abstract: A flexible object has a flexible body being flexible and at least one decorative light attached to the flexible body and having a light strand and multiple threads. The light strand of each one of the at least one decorative light has a cord and multiple light emission diode units. The multiple light emission diode units are electrically connected to one another in series via the cord and are arranged along the cord. The multiple threads of each one of the at least one decorative light are sewed on the flexible body to fix the light strand of the decorative light to the flexible body. The multiple threads of each one of the at least one decorative light has a first thread wavily extending along and across the cord of the light strand of the decorative light.

Abstract: A decorative light can include: a housing defining an interior space and having an open front; a cover mounted to the open front of the housing, the cover including a beam-splitter light lens shade and a substantially planar lens portion disposed around the beam-splitter light lens shade; a motor located in the interior space of the housing, the motor including an output shaft; a first light module located in the interior space and including first light units disposed about the output shaft of the motor, where the output shaft is rotatable with respect to the first light units; a second light module located in the interior space and including second light units disposed about the output shaft of the motor, wherein the output shaft is rotatable with respect to the second light units; and a rotating lens module connected to the output shaft of the motor for rotation.

Abstract: A waterproof lamp decoration has a lamp unit having a waterproof illumination unit and a lamp cover detachably engaged with the waterproof illumination unit. The waterproof illumination unit has a transparent shell, an end cap, a lamp board, multiple conducting wires, and an encapsulating body. The lamp board is mounted in a chamber formed between the transparent shell and the end cap. The conducting wires are mounted through the end cap from the chamber. The encapsulating body joins and surrounds a connecting portion of the transparent shell, the end cap, and the conducting wires and seals gaps formed among them to seal the chamber, and to prevent moisture from entering the chamber, so as to ensure the waterproof effect of the waterproof illumination. The lamp cover is changeable to enhance variability of illumination and decorativeness of the waterproof lamp decoration.

Abstract: Examples described herein provide a method for optimizing a netlist for an integrated circuit device. The method generally includes receiving a netlist comprising a first lookup table, and upstream logic, wherein the upstream logic receives a plurality of input signals and comprises at least one output connected as at least one input to the first lookup table, wherein the first lookup table comprises an unused input and multiple outputs; mapping the plurality of input signals directly to the at least one input and the unused input of the first lookup table; validating the mapping by monitoring the multiple outputs of the first lookup table; and upon a successful validation, optimizing the netlist by removing the upstream logic and reconnecting the plurality of input signals to the at least one input and the unused input of the first lookup table.

Abstract: A rotary image projector includes a lamp shade, a power board, a driver, and a projection module. The power board is mounted to the lamp shade. The driver is disposed in the lamp shade and electrically connected to the power board. The projection module is driven to rotate by the driver and has a luminous element, a collective lens, and at least two projection assemblies. The luminous element is electrically connected to the power board. The collective lens is spaced apart from the luminous element. Each one of the at least two projection assemblies is disposed on one of two sides of the collective lens away from the luminous element and has a positioning sleeve, a film, and at least one imaging lens. The film is mounted to the positioning sleeve. The at least one imaging lens is mounted to the positioning sleeve.

Abstract: The present disclosure relates to the preparation of methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate (ITE) and related compounds with high yield, purity, and scalability. The processes apply the use of a Weinreb amide intermediate as a scaffold for the preparation of ITE and structural analogs.

Abstract: Provided herein are efficient, scalable methods for in vitro production of human retinal progenitor cells. In addition, provided herein are methods for isolating pure populations of in vitro produced human retinal progenitor cells as well as kits and compositions comprising such pure populations of human retinal progenitor cells.

Abstract: Systems and methods which provide a compact spectrometer using static Fourier transform interferometer (SFTI) cube configurations, such as are suitable for use with respect to mobile and portable electronic devices, are described. A SFTI cube of embodiments comprises a monolithic dual mirrored wedge beam splitter structure wherein mirrored wedge surfaces provide two reflective mirrors that are slightly tilted away from the orthogonal directions so that the resultant beams of light cross over one another and form an interference pattern. SFTI cube implementations of embodiments facilitate highly compact spectrometer configurations having a wide wavelength range, high resolution, high throughput, and low cost.