Abstract: A grooving insert includes a front surface and an opposite rear surface, a first side surface and an opposite second side surface, and a top surface and an opposite bottom surface. The top surface includes a top front portion and a top rear portion, the top front portion having a cutting edge arranged symmetrically relative to a first plane. The bottom surface is symmetrically arranged in relation to a second plane, the first plane and the second plane forming an angle (?) of 0.5-5.0° relative to each other.

Abstract: A grooving insert includes a front surface and an opposite rear surface, a first side surface and an opposite second side surface, and a top surface and an opposite bottom surface. The top surface includes a top front portion and a top rear portion, the top front portion having a cutting edge arranged symmetrically relative to a first plane. The bottom surface is symmetrically arranged in relation to a second plane, the first plane and the second plane forming an angle (?) of 0.5-5.0° relative to each other.

Abstract: The present invention relates to a process for purification of recombinant alpha-mannosidase, a process for production of alpha-mannosidase, a composition comprising alpha-mannosidase, use of the composition as a medicament, use as a medicament for the treatment of alpha-mannosidosis and a method of treating alpha-mannosidosis and/or alleviating the symptoms of alpha-mannosidosis.

Abstract: A technique for assigning spectral resources in a cellular network for wireless communications is described. The spectral resources are partly utilized by other applications. As to a method aspect of the technique, a controller (100) of the cellular network receives information (702) indicative of one or more geographical areas and restrictions within the one or more geographical areas (1002). The spectral resources are assigned based on the received information (702).

Abstract: The present invention relates to an animal model for infantile globoid cell leucodystrophy, and use of said animal model for screening and/or validation of agents which may be useful as a medicament for treatment of globoid cell leukodystrophy.

Abstract: The present invention pertains to a process for production of recombinant arylsulfatase A in a cell culture system, the process comprising culturing a mammalian cell capable of producing rASA in liquid medium in a system comprising one or more bio-reactors; and concentrating, purifying and formulating the rASA by a purification process comprising one or more steps of chromatography. Other aspects of the invention provides a pharmaceutical composition comprising rASA, which is efficiently endocytosed via the mannose-6-phosphate receptor pathway in vivo as well as a rhASA a medicament and use of a rhASA for the manufacture of a medicament for reducing the galactosyl sulphatide levels within target cells in the peripheral nervous system and/or within the central nervous system in a subject.

Abstract: The present invention relates to a process for purifying recombinant human Galactocerebroside ?-Galactosidase (rhGALC) from a cell culture, wherein a fraction of said cell culture comprising rhGALC is subjected to chromatography on three distinct resins.

Abstract: The present invention relates to a process for purification of recombinant alpha-mannosidase, a process for production of alpha-mannosidase, a composition comprising alpha-mannosidase, use of the composition as a medicament, use as a medicament for the treatment of alpha-mannosidosis and a method of treating alpha-mannosidosis and/or alleviating the symptoms of alpha-mannosidosis.

Abstract: The invention relates to a method in a reporting communications node (12, 14) for detecting usage of a resource within a radio access network. The reporting communication node (12, 14) is comprised within a radio communications network (1), in which radio communications network (1) a user equipment (12) is served. The reporting communications node monitors a performance measurement per user equipment of the user equipment (12), which performance measurement indicates usage of resources within a radio access network. The reporting communication node detects when the performance measurement per user equipment of the user equipment (12) goes beyond a threshold value over a preset period of time. In addition, the reporting communication node reports to a different communication node (14, 15) or within the communication node (12, 14), the performance measurement per user equipment when the performance measurement per user equipment goes beyond the threshold value.

Abstract: A parting tool for the chip removing machining of metal blanks includes a blade and a replaceable cutting insert mounted in a seat, which is delimited between a bottom support and an elastically resilient clamping finger. The cutting insert includes an upper side, in which there is included a front rake surface, as well as an application surface positioned behind the same and against which the clamping finger is pressed. In the clamping finger, a flushing channel is included to spray a cooling medium toward the rake surface. A front nose of the clamping finger facing a shoulder is formed between the rake surface and the application surface and has the purpose of protecting the nose from chips. The shoulder has two knobs mutually separated by a central notch, via which cooling medium can pass from the flushing channel toward the rake surface.

Abstract: A technique for assigning spectral resources in a cellular network for wireless communications is described. The spectral resources are partly utilized by other applications. As to a method aspect of the technique, a controller (100) of the cellular network receives information (702) indicative of one or more geographical areas and restrictions within the one or more geographical areas (1002). The spectral resources are assigned based on the received information (702).

Abstract: The present invention relates to a process for purification of recombinant alpha-mannosidase, a process for production of alpha-mannosidase, a composition comprising alpha-mannosidase, use of the composition as a medicament, use as a medicament for the treatment of alpha-mannosidosis and a method of treating alpha-mannosidosis and/or alleviating the symptoms of alpha-mannosidosis.

Abstract: The present invention relates to a process for purifying recombinant human Galactocerebroside ?-Galactosidase dase (rhGALC) from a cell culture, wherein a fraction of said cell culture comprising rhGALC is subjected to chromatography on three distinct resins.

Abstract: The present invention relates to an animal model for infantile globoid cell leucodystrophy, and use of said animal model for screening and/or validation of agents which may be useful as a medicament for treatment of globoid cell leukodystrophy.

Abstract: The present invention relates to a process for purification of recombinant alpha-mannosidase, a process for production of alpha-mannosidase, a composition comprising alpha-mannosidase, use of the composition as a medicament, use as a medicament for the treatment of alpha-mannosidosis and a method of treating alpha-mannosidosis and/or alleviating the symptoms of alpha-mannosidosis.

Abstract: A parting tool for the chip removing machining of metal blanks includes a blade and a replaceable cutting insert mounted in a seat, which is delimited between a bottom support and an elastically resilient clamping finger. The cutting insert includes an upper side, in which there is included a front rake surface, as well as an application surface positioned behind the same and against which the clamping finger is pressed. In the clamping finger, a flushing channel is included to spray a cooling medium toward the rake surface. A front nose of the clamping finger facing a shoulder is formed between the rake surface and the application surface and has the purpose of protecting the nose from chips. The shoulder has two knobs mutually separated by a central notch, via which cooling medium can pass from the flushing channel toward the rake surface.

Abstract: Method for retrieving data from an object database stored in a server (220) as a network (501) of objects (502) connected via links (503), said method including the steps of: storing (301) said object database in a server (220); forming (302) at a client (210) a request for a requested object (903) of a predetermined identity in said database and objects (904) connected to said requested object (903); transmitting (303) said request from said client (210) to said server (220) over a computer network (230); creating a data package containing said requested object (903) and objects connected to said requested object; and transmitting (306) said data package to said client. The invention furthermore relates to a system for retrieving data from an object database, a server, a computer program, a computer program product and a computer system.

Abstract: In a method and a device a detection mechanism enabling a cellular radio system to detect deployment of two or more radio base stations having a small coverage area close to each other and configured to use the same scrambling code is provided. The detected information can be used as a trigger to automatically reconfigure one of the radio base stations having a small coverage area.

Abstract: The present invention pertains to a process for production of recombinant arylsulfatase A in a cell culture system, the process comprising culturing a mammalian cell capable of producing rASA in liquid medium in a system comprising one or more bio-reactors; and concentrating, purifying and formulating the rASA by a purification process comprising one or more steps of chromatography. Other aspects of the invention provides a pharmaceutical composition comprising rASA, which is efficiently endocytosed via the mannose-6-phosphate receptor pathway in vivo as well as a rhASA a medicament and use of a rhASA for the manufacture of a medicament for reducing the galactosyl sulphatide levels within target cells in the peripheral nervous system and/or within the central nervous system in a subject.

Abstract: The present invention pertains to a process for production of recombinant arylsulfatase A in a cell culture system, the process comprising culturing a mammalian cell capable of producing rASA in liquid medium in a system comprising one or more bio-reactors; and concentrating, purifying and formulating the rASA by a purification process comprising one or more steps of chromatography. Other aspects of the invention provides a pharmaceutical composition comprising rASA, which is efficiently endocytosed via the mannose-6-phosphate receptor pathway in vivo as well as a rhASA a medicament and use of a rhASA for the manufacture of a medicament for reducing the galactosyl sulphatide levels within target cells in the peripheral nervous system and/or within the central nervous system in a subject.