Abstract: The present disclosure provides compounds for modulating calcitonin receptor and/or amylin receptor activity, as well as pharmaceutical compositions comprising the compounds disclosed herein. Also provided are methods for treating a calcitonin receptor and/or amylin receptor associated disease or disorder.

Abstract: The present disclosure provides compounds for modulating calcitonin receptor and/or amylin receptor activity, as well as pharmaceutical compositions comprising the compounds disclosed herein. Also provided are methods for treating a calcitonin receptor and/or amylin receptor associated disease or disorder.

Abstract: The present disclosure provides a data processing method, an outdoor unit (IDU), an indoor unit (ODU), and a computer-readable storage medium. The method performed by an IDU communicating with an ODU may include: receiving an operation status signal from a user-side device; generating a Subscriber Line Interface Circuit (SLIC) event message corresponding to the operation status signal according to the operation status signal; generating a first SLIC control flow according to the SLIC event message, where the first SLIC control flow carries first label information corresponding to the SLIC event message; and sending the first SLIC control flow to the ODU, where the first label information indicates the SLIC event message which is processible to a voice protocol stack.

Abstract: The subject matter described herein is directed to somatostatin receptor activating compounds, methods of making the compounds, pharmaceutical compositions, and their use in the treatment of diseases associated with somatostatin receptors.

Abstract: The present disclosure provides compounds for modulating calcitonin receptor and/or amylin receptor activity, as well as pharmaceutical compositions comprising the compounds disclosed herein. Also provided are methods for treating a calcitonin receptor and/or amylin receptor associated disease or disorder.

Abstract: A fudosteine nebulization inhalation solution composition and use thereof. The fudosteine nebulization inhalation solution consists of fudosteine, a pH-adjusting agent and water. The droplet particle size of the composition is as follows: the D90 particle size is 7.0-10.0 ?m, the D50 particle size is 2.8-4.5 ?m, and the Dio particle size is 0.5-1.5 ?m; and the percent deposition of the particles with the aerodynamic particle size of 1.4-5.4 ?m in the fudosteine inhalation solution is not less than 50%. In addition, further provided is a drug assembly for use in conjunction with the nebulization inhalation solution, comprising the inhalation composition, and a nebulizer and a nebulizing cup with specific parameters. The fudosteine nebulization inhalation solution composition and the assembly thereof have the advantages of a small effective dose, acting fast, high drug delivery efficiency, and the like, and are particularly effective in treating tracheal and main bronchial diseases.

Abstract: The present disclosure provides compounds for modulating calcitonin receptor and/or amylin receptor activity, as well as pharmaceutical compositions comprising the compounds disclosed herein. Also provided are methods for treating a calcitonin receptor and/or amylin receptor associated disease or disorder.

Abstract: This application pertains to antibodies or antigen binding fragments that specifically recognize Growth differentiation factor-15 (GDF15), and methods of manufacture and uses thereof.

Abstract: The present disclosure provides compounds for modulating calcitonin receptor and/or amylin receptor activity, as well as pharmaceutical compositions comprising the compounds disclosed herein. Also provided are methods for treating a calcitonin receptor and/or amylin receptor associated disease or disorder.

Abstract: The present disclosure provides a preparation and application of high-activity and high-safety Cardamine violifolia selenoprotein standard sample. The standard sample of the Cardamine violifolia selenoprotein prepared by the present disclosure has the advantages of extremely low heavy metal content, less ash, high protein content, high total selenium content, high organic selenium ratio of up to 99.9%, high biological activity, high safety and so on; the organic selenium is mainly in form of selenocysteine/selenocystine and accounts for more than 90% of the total selenium content, and is expected to make up for the shortage of selenoprotein standard samples on the market.

Abstract: The present disclosure provides a preparation and application of high-activity and high-safety Cardamine violifolia selenoprotein standard sample. The standard sample of the Cardamine violifolia selenoprotein prepared by the present disclosure has the advantages of extremely low heavy metal content, less ash, high protein content, high total selenium content, high organic selenium ratio of up to 99.9%, high biological activity, high safety and so on; the organic selenium is mainly in form of selenocysteine/selenocystine and accounts for more than 90% of the total selenium content, and is expected to make up for the shortage of selenoprotein standard samples on the market.

Abstract: A method for managing an ECU on a vehicle, and an ECU and a computer-readable storage medium are disclosed. The method may include: monitoring a working state of at least one ECU on a vehicle (S201); and in response to detecting an abnormal ECU in an abnormal working state, sending a control instruction to the abnormal ECU, where the control instruction is configured to trigger the abnormal ECU to execute a corresponding restore action (S202).

Abstract: Provided is an RNA, siRNA, shRNA or nucleic acid coding for shRNA, combination of RNAs, combination of siRNAs, combination of shRNAs, or combination of the nucleic acids coding for shRNAs targeting HIV. Also provided are an expression cassette, recombinant vector, recombinant virus particle, kit, cell or pharmaceutical composition comprising the above sequences or combinations and their use for preparing drugs for diagnosis, treatment and/or prevention of HIV infection or AIDS.

Abstract: The present disclosure provides compounds for modulating calcitonin receptor and/or amylin receptor activity, as well as pharmaceutical compositions comprising the compounds disclosed herein. Also provided are methods for treating a calcitonin receptor and/or amylin receptor associated disease or disorder.

Abstract: The present disclosure provides compounds for modulating calcitonin receptor and/or amylin receptor activity, as well as pharmaceutical compositions comprising the compounds disclosed herein. Also provided are methods for treating a calcitonin receptor and/or amylin receptor associated disease or disorder.

Abstract: The present disclosure provides a data processing method, an outdoor unit (IDU), an indoor unit (ODU), and a computer-readable storage medium. The method performed by an IDU communicating with an ODU may include: receiving an operation status signal from a user-side device; generating a Subscriber Line Interface Circuit (SLIC) event message corresponding to the operation status signal according to the operation status signal; generating a first SLIC control flow according to the SLIC event message, where the first SLIC control flow carries first label information corresponding to the SLIC event message; and sending the first SLIC control flow to the ODU, where the first label information indicates the SLIC event message which is processible to a voice protocol stack.

Abstract: A method for managing an ECU on a vehicle, and an ECU and a computer-readable storage medium are disclosed. The method may include: monitoring a working state of at least one ECU on a vehicle (S201); and in response to detecting an abnormal ECU in an abnormal working state, sending a control instruction to the abnormal ECU, where the control instruction is configured to trigger the abnormal ECU to execute a corresponding restore action (S202).

Abstract: Provided are antibodies including antigen-binding fragment thereof that specifically recognizing Nerve Growth Factor NGF). Also provided are methods of making and using these antibodies.

Abstract: Embodiments of the subject matter described herein relate to generating a decision tree based on data pre-statistics. A plurality of data samples for a node of the decision tree are obtained, and the plurality of data samples have corresponding feature values with respect to a first feature. A target range is determined from a plurality of predefined numerical ranges so that the number of feature values falling into the target range is greater than a predetermined threshold number. Then, the remaining of the feature values other than the feature values falling into the target range are assigned to the respective numerical ranges, and the feature values falling into all the numerical ranges are counted based on the assignment of the remaining of the feature values, for allocation of the plurality of data samples to child nodes of the node. Accordingly, the data processing efficiency is substantially improved.

Abstract: An ejector-based cryogenic refrigeration system for cold energy recovery includes a first cryogenic refrigeration loop connected by a helium compressor and a cryogenic refrigerator and a second cryogenic refrigeration loop connected by the helium compressor, a regenerator, an ejector, a cold head of the cryogenic refrigerator, an end to be cooled and a pressure regulating valve. The cryogenic refrigerator is separated from the end to be cooled. The cryogenic refrigerator and the cryogenic helium cooling loop share a helium compressor, which improves the utilization efficiency of the device and reduces the cost. The ejector allows a part of fluids to circulate in the cryogenic loop, so as to maintain a required cryogenic condition, recover the pressure of the fluids, reduce the gas flowing though the compressor loop, and thus reduce the power consumption of the compressor.